NEOGEN X SUR.MEDIC

NEOGEN X SUR.MEDIC DERMALOGY H2 DERMADECA SERUM SPRAY

Name: NEOGEN X SUR.MEDIC - DERMALOGY H2 DERMADECA SERUM SPRAY
Brand: NEOGEN X SUR.MEDIC

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Niacinamide, Madecassoside + 8 more

Works well

What the product description says

“Fine mist mechanism infused with Centella Asiatica and Allantoin delivers calming, hydrating, refining, and repairing benefits to the skin evenly across the skin.”

Source: Neogenlab

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": allantoin, glycerin.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.4–2.9%

MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.3%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.1–3.8%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1.9–2.4%

AllantoinKey active· HumectantEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~1.5–1.8%

Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1–1.2%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.55–0.85%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.25–0.5%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.2–0.35%

CyclohexasiloxaneEffect: Low, below effective doseA silicone that serves as an emollient. Helps create a nice non-greasy feels~0.25–0.5%

Anti-oxidation

Side benefit · Centella asiatica extract, Madecassoside + 4 more

Works well

This product contains antioxidants (madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - centella asiatica extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1–1.2%

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.3%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1.9–2.4%

Pelargonium graveolens flower oilEffect: LowAn essential oil. Can be irritating. Can become an allergen with oxidation~0.5–0.75%

Rose flower oilEffect: LowFlower oil that is used as a fragrance~0.4–0.6%

Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~1.5–1.8%

Anti-blemish

Side benefit · Niacinamide, Allantoin + 1 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

AllantoinEffect: LowHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~1.5–1.8%

Centella asiatica extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~1–1.2%

Evens skin tone

Side benefit · Niacinamide, Madecassoside + 1 more

Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~2.4–2.9%

MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.3%

Anti-aging

Side benefit · Niacinamide, Adenosine + 3 more

Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: centella asiatica extract, madecassoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~1.9–2.4%

MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.15–0.3%

Can it cause trouble?

Irritancy

9 strong irritants: Alcohol denat., Allium cepa bulb extract + 7 more — patch-test recommended

High risk

We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~8.2–10%est.

Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~1.5–1.8%est.

Allium cepa bulb extract—High~0.9–1.15%est.

Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.5–0.75%est.

Mentha piperita oilUsed as a fragrance and can be irritatingHigh~0.4–0.6%est.

Citrus aurantium dulcis oilUsed as a fragrance. It can be irritating and cause photosensitivityHigh~0.45–0.65%est.

Chamomilla recutita flower oilPlant oil that can have healing and anti-inflammatory properties. It contains volatile compouunds that are potential allergens and can be irritatingHigh~0.4–0.6%est.

Rose flower oilFlower oil that is used as a fragranceHigh~0.4–0.6%est.

Citrus aurantium bergamia fruit oilA plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivityHigh~0.3–0.55%est.

Lavandula hybrida oilPlant extract that can be irritating and is a known allergenHigh~0.25–0.5%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~1–1.2%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.55–0.85%est.

Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~0.25–0.45%est.

MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.15–0.3%est.

1,2-hexanediolA preservativeMedium~0.15–0.25%est.

EthylhexylglycerinA preservativeMedium~0.1–0.2%est.

Disodium edtaStabilizes the product formulationMedium~0.05–0.1%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

Alternatives

The closest match we found

Skin Republic Vitamin C 6% & Alpha Arbutin 1.5% Serum

Closest match80% match

View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Alcohol denat.~8.2–10%

Irritant · high

Irritation risk: High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.

Dipropylene glycol~4.4–5.3%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Glycerin~3.1–3.8%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Niacinamide~2.4–2.9%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-blemishMoisturizingAnti-agingReduces irritationReduces rednessAnti-inflammatoryAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Adenosine~1.9–2.4%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Allantoin~1.5–1.8%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Ascorbic acid~1.5–1.8%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-agingAnti-oxidation

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid

Centella asiatica extract~1–1.2%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryReduces irritationMoisturizingReduces rednessAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Allium cepa bulb extract~0.9–1.15%

Irritant · high

Irritation risk: High

More about Allium cepa bulb extract

Tuber magnatum extract~0.65–1%

Formula

Irritation risk: Low

More about Tuber magnatum extract

Olea europaea fruit oil~0.55–0.85%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Pelargonium graveolens flower oil~0.5–0.75%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil

Mentha piperita oil~0.4–0.6%

Irritant · high

Irritation risk: High

Used as a fragrance and can be irritating

More about Mentha piperita oil

Citrus aurantium dulcis oil~0.45–0.65%

Irritant · high

Irritation risk: High

Used as a fragrance. It can be irritating and cause photosensitivity

More about Citrus aurantium dulcis oil

Chamomilla recutita flower oil~0.4–0.6%

Irritant · high

Irritation risk: High

Plant oil that can have healing and anti-inflammatory properties. It contains volatile compouunds that are potential allergens and can be irritating

More about Chamomilla recutita flower oil

Rose flower oil~0.4–0.6%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Flower oil that is used as a fragrance

More about Rose flower oil

Citrus aurantium bergamia fruit oil~0.3–0.55%

Irritant · high

Irritation risk: High

A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity

More about Citrus aurantium bergamia fruit oil

Lavandula hybrida oil~0.25–0.5%

Irritant · high

Irritation risk: High

Plant extract that can be irritating and is a known allergen

More about Lavandula hybrida oil

Cyclopentasiloxane~0.25–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Cyclohexasiloxane~0.25–0.5%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

Peg-60 hydrogenated castor oil~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil

Butylene glycol~0.2–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Madecassoside~0.15–0.3%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside

1,2-hexanediol~0.15–0.25%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Ethylhexylglycerin~0.1–0.2%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Phenoxyethanol~0.1–0.25%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Disodium edta~0.05–0.1%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Ingredient list view

Water, Alcohol denat., Dipropylene glycol, Glycerin, Niacinamide, Adenosine, Allantoin, Ascorbic acid, Centella asiatica extract, Allium cepa bulb extract, Tuber magnatum extract, Olea europaea fruit oil, Pelargonium graveolens flower oil, Mentha piperita oil, Citrus aurantium dulcis oil, Chamomilla recutita flower oil, Rose flower oil, Citrus aurantium bergamia fruit oil, Lavandula hybrida oil, Cyclopentasiloxane, Cyclohexasiloxane, Peg-60 hydrogenated castor oil, Butylene glycol, Madecassoside, 1,2-hexanediol, Ethylhexylglycerin, Phenoxyethanol, Disodium edta

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	NEOGEN X SUR.MEDICDERMALOGY H2 DERMADECA SERUM SPRAYYOUR PRODUCT	Skin RepublicVitamin C 6% & Alpha Arbutin 1.5% Serum	Vitabrid13 YEARS YOUNGER WRINKLE SERUM PROFESSIONAL: REGULAR PRICE \| Vitabrid US	Some By MiGalactomyces Pure Vitamin C Glow Serum
Match	—	80%	78%	77%
Price	—	—	—	$14.20
Shared key ingredients	—	3 of 8	5 of 8	5 of 8
Key difference	—	Panthenol	Copper Tripeptide-1	Pitera
Irritancy	High	Medium	Medium	High
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Neogen - DERMALOGY H2 DERMADECA SERUM SPRAY" is effective for: Anti-inflammatory, Moisturizing, Anti-blemish, Evens skin tone and Anti-aging

Ingredient callouts

A good concentration of Niacinamide (2.40% - 2.90%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this product it is used for stabilizing other ingredients in the formulation. In this concentration (1.50% - 1.80%) it cannot have a noticeable benefit for the skin.
Adenosine 1.90% - 2.40%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.15% - 0.30% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
In addition, this product contains Allantoin (1.50% - 1.80%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.
Humectants (glycerin 3.10% - 3.80% and allantoin 1.50% - 1.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.