Neocutis BIO Cream Firm

Neocutis BIO Cream Firm

Efficacy100/100IrritancyMedium
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Works for

3 of 3 advertised claims delivered

Moisturizing
21 ingredients credited for this claim
Strong support
What the product description says
“A synergistic formulation to boost collagen, elastin, and hyaluronic acid for a more youthful appearance.”
Source: Lookfantastic US

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, caprylyl glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, borago officinalis seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ap, ceramide eop, ceramide ng, ceramide np, niacinamide, palmitoyl tripeptide-1 acetate, phytosphingosine, tetrapeptide-21

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.55%
Tetrapeptide-21HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2–2.5%
Borago officinalis seed oilKey active· EmollientEffect: HighA plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration~0.5–0.75%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Ceramide ngHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.6%
Palmitoyl tripeptide-1 acetateHeroEffect: High~0.5–0.7%
PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.25–0.5%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.5–0.75%
Ceramide apHeroEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%
Ceramide eopHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.35–0.65%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.7–1.05%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.35–0.6%
Decyl oleateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~3.1–3.8%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.35–0.65%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~3.5–4.3%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~4.5–5.5%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~1.8–2.1%
Argania spinosa kernel oilUnder-dosedEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.75–1.1%
Evens skin tone
1 ingredient credited for this claim
Strong support
What the product description says
“Preserve with Growth Factors Visible improvement in the look of fine lines and wrinkles; Improves skin tone and texture; Enhances the feel of skin smoothness Intensively revitalize with Proprietary Peptides Proprietary Peptides help skin look firmer and feel tighter; Supports collagen and elastin production Hydrate Increases skin hydration for enhanced skin smoothness and luminosity; Nourishing oils moisturize skin to promote a more refined tone and texture Replenish healing skin Helps support healing skin after cosmetic or dermatological treatments”
Source: Lookfantastic US

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Anti-aging
3 ingredients credited for this claim
Strong support
What the product description says
“A synergistic formulation to boost collagen, elastin, and hyaluronic acid for a more youthful appearance.”
Source: Lookfantastic US

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: palmitoyl tripeptide-1 acetate, tetrapeptide-21.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
Tetrapeptide-21Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Palmitoyl tripeptide-1 acetateKey activeEffect: Medium~0.5–0.7%
Anti-blemish
Not advertised by the brand · 2 ingredients credited for this claim
Good support

This product might be able to help reduce blemishes and clogged pores because it contains niacinamide.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%
PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.25–0.5%

Can it cause trouble?

Irritancy
13 flagged ingredients
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~2.3–2.8%est.
Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~1.3–1.5%est.
Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.75–1.1%est.
Sodium lauroyl lactylateHelps water and oil mix togetherMedium~0.5–0.75%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.4–0.6%est.
Potassium sorbateA preservativeMedium~0.3–0.6%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.35–0.65%est.
Ceteareth-12Helps water and oil mix togetherMedium~0.3–0.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.55%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.
EthylhexylglycerinA preservativeMedium~0.15–0.3%est.
BhtA preservativeMedium~0.05–0.15%est.
Disodium edtaStabilizes the product formulationMedium~0.05%est.
Comedogenic
3 ingredients rated 2 or more on the 0–5 pore-clogging scale
3 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Decyl oleateHelps soften the upper layer of the skin2/5~3.1–3.8%est.
Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~1.3–1.5%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.35–0.65%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Octyldodecanol~4.5–5.5%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Glyceryl stearate~3.5–4.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Decyl oleate~3.1–3.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Decyl oleate
Propylene glycol~2.3–2.8%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Glycerin~2–2.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Stearic acid~1.8–2.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Niacinamide~1.4–1.8%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationReduces rednessAntibacterialAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Ceteareth-20~1.3–1.5%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20
Argania spinosa extract~0.95–1.15%
Formula
Argania spinosa kernel oil~0.75–1.1%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil
Cetyl alcohol~0.7–1.05%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Cutaneous lysate~0.55–0.85%
Formula
Tetrapeptide-21~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tetrapeptide-21
Palmitoyl tripeptide-1 acetate~0.5–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Palmitoyl tripeptide-1 acetate
Sodium lauroyl lactylate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sodium lauroyl lactylate
Borago officinalis seed oil~0.5–0.75%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationMoisturizingAnti-oxidation

A plant oil that is effective in reducing irritation in skin, restore the barrier function and support its hydration

More about Borago officinalis seed oil
Dimethicone~0.5–0.75%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Citric acid~0.4–0.6%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Potassium sorbate~0.3–0.6%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Capryloyl carnosine~0.3–0.6%
Formula
Caprylyl glycol~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ceteareth-12~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteareth-12
Cetearyl alcohol~0.35–0.65%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Cetyl palmitate~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Ceramide ng~0.3–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ng
Myreth-3 myristate~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Myreth-3 myristate
Tocopheryl acetate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Carbomer~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Hexylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Ceramide np~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Ceramide ap~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ap
Phytosphingosine~0.25–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine
Cholesterol~0.25–0.5%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Xanthan gum~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ethylhexylglycerin~0.15–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ceramide eop~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces irritationMoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide eop
Sodium hydroxide~0.1–0.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Bht~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Disodium edta~0.05%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Phenoxyethanol~0.1–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Octyldodecanol, Glyceryl stearate, Decyl oleate, Propylene glycol, Glycerin, Stearic acid, Niacinamide, Ceteareth-20, Argania spinosa extract, Argania spinosa kernel oil, Cetyl alcohol, Cutaneous lysate, Tetrapeptide-21, Palmitoyl tripeptide-1 acetate, Sodium lauroyl lactylate, Borago officinalis seed oil, Dimethicone, Citric acid, Potassium sorbate, Capryloyl carnosine, Caprylyl glycol, Ceteareth-12, Cetearyl alcohol, Cetyl palmitate, Ceramide ng, Myreth-3 myristate, Tocopheryl acetate, Carbomer, Hexylene glycol, Ceramide np, Ceramide ap, Phytosphingosine, Cholesterol, Xanthan gum, Ethylhexylglycerin, Ceramide eop, Sodium hydroxide, Bht, Disodium edta, Phenoxyethanol

Compare prices

Retailers ranked by price — lowest first.

Lookfantastic US
$178.00
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Dermstore
$178.00
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Amazon USPrice as of 10/9/2026 21:20 GMT
$208.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NeocutisBIO Cream FirmYOUR PRODUCTCeraVePsoriasis Moisturizing CreamKey SoulcareSKIN TRANSFORMATION CREAM FRAGRANCE FREEe.l.f. CosmeticsPure Skin Moisturizer
Match—84%83%82%
Price$178.00—$34.00−$144.00$11.81−$166.19
Shared key ingredients—8 of 138 of 137 of 13
Key difference—Salicylic AcidBakuchiolSodium Hyaluronate
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"Neocutis - BIO Cream Firm" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Neocutis - BIO Cream Firm ticks this box. Humectants in this product (glycerin and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide eop, ceramide ng, ceramide np, phytosphingosine and borago officinalis seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • As a plus, this moisturizer also contains ceramides (ceramide eop 0.20% - 0.35%, phytosphingosine 0.25% - 0.50%, ceramide ap 0.25% - 0.45%, ceramide np 0.30% - 0.55% and ceramide ng 0.30% - 0.60%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • This moistruizer also contains peptides (palmitoyl tripeptide-1 acetate 0.50% - 0.70% and tetrapeptide-21 0.50% - 0.75%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 178.00$ up to 197.00$ in the United States and for 224.30CA$ in Canada.

For a detailed price comparison: click here.

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.