Natura Siberica Lab Biome Peptide Face Cream

Natura Siberica Lab Biome Peptide Face Cream

Efficacy87/100IrritancyHigh
Edit

Works for

2 of 2 advertised claims delivered

Moisturizing
12 ingredients credited for this claim
Strong support
What the product description says
“They increase skin's resistance to the effects of an urban lifestyle, improve skin's radiance and regeneration, while keeping it healthy and helping to keep it young and natural.It is complemented by SYN®-COLL peptide, which stimulates the synthesis of natural collagen in skin cells, helps smooth wrinkles to prolong skin's youthful appearance.Hyaluronic acid of high and low molecular weight, a powerful moisturizer that also prevents the appearance of wrinkles and fine lines.”
Source: Cocoon Center

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, lactobacillus ferment.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tripeptide-5

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~4.1–5%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%
Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~0.6–0.9%
Dipeptide diaminobutyroyl benzylamide diacetateHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.4–1.7%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.2–3.9%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.3–2.8%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.1–1.4%
Aloe barbadensis leaf juice· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~6.2–7.5%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1.6–1.9%
Anti-aging
4 ingredients credited for this claim
Moderate support
What the product description says
“They increase skin's resistance to the effects of an urban lifestyle, improve skin's radiance and regeneration, while keeping it healthy and helping to keep it young and natural.It is complemented by SYN®-COLL peptide, which stimulates the synthesis of natural collagen in skin cells, helps smooth wrinkles to prolong skin's youthful appearance.Hyaluronic acid of high and low molecular weight, a powerful moisturizer that also prevents the appearance of wrinkles and fine lines.”
Source: Cocoon Center

This product contains dipeptide diaminobutyroyl benzylamide diacetate, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Dipeptide diaminobutyroyl benzylamide diacetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2–2.4%
Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~6.2–7.5%

Can it cause trouble?

Irritancy
9 strong irritants: Salvia officinalis leaf extract, Origanum vulgare flower/leaf/stem extract + 7 more — patch-test recommended
High risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salvia officinalis leaf extractSage leaf extract. It can be irritatingHigh~0.45–0.7%est.
Thymus vulgaris extract—High~0.3–0.55%est.
Ocimum basilicum leaf extractUsed as a frangrance. Can be irritating. Might have some anti-bacterial propertiesHigh~0.25–0.5%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.2–0.35%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.
Ci 15985A colorantHigh~0.2–0.35%est.
Ci 19140A yellow dyeHigh~0.15–0.3%est.
GeraniolA fragrance. Can be irritatingHigh~0.1–0.25%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.1–0.2%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.1–0.15%est.
LinaloolA fragrance. Can be irritatingHigh~0.05–0.1%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~6.2–7.5%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.2–3.9%est.
Rubus idaeus fruit extractA fruit extract that might have some anti-oxidant properties but evidence of effectiveness in skin is lackingMedium~0.4–0.6%est.
Epilobium angustifolium extractA plant extract that might help neutralize free radicals and calm down irritation in skin. However, it can contain compounds that can be irritating themselvesMedium~0.25–0.45%est.
Sodium stearoyl glutamateHelps oil and water mix togetherMedium~0.3–0.55%est.
EthylhexylglycerinA preservativeMedium~0.2–0.4%est.
Potassium sorbateA preservativeMedium~0.2–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.35%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2–2.4%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.3–2.8%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Aloe barbadensis leaf juice~6.2–7.5%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces rednessReduces irritationAntibacterialAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Helianthus annuus seed oil~4.1–5%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Caprylic/capric triglyceride~3.2–3.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cetearyl alcohol~2.3–2.8%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butyrospermum parkii butter~2–2.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Glyceryl stearate citrate~1.6–1.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Glycerin~1.4–1.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Glyceryl stearate~1.1–1.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Maltodextrin~0.95–1.15%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Lactobacillus ferment~0.6–0.9%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-oxidationReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Palmitoyl tripeptide-5~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Rubus chamaemorus fruit extract~0.5–0.75%
Formula
Rubus idaeus fruit extract~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A fruit extract that might have some anti-oxidant properties but evidence of effectiveness in skin is lacking

More about Rubus idaeus fruit extract
Dipeptide diaminobutyroyl benzylamide diacetate~0.4–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Dipeptide diaminobutyroyl benzylamide diacetate
Salvia officinalis leaf extract~0.45–0.7%
Irritant · high
Irritation risk
High

Sage leaf extract. It can be irritating

More about Salvia officinalis leaf extract
Origanum vulgare flower/leaf/stem extract~0.35–0.65%
Irritant · high
Thymus vulgaris extract~0.3–0.55%
Irritant · high
Acetum~0.3–0.55%
Formula
Irritation risk
Low
More about Acetum
Boreale flower/leaf/stem extract
Not recognized
Ocimum basilicum leaf extract~0.25–0.5%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Used as a frangrance. Can be irritating. Might have some anti-bacterial properties

More about Ocimum basilicum leaf extract
Sus extract~0.25–0.45%
Formula
Irritation risk
Low
More about Sus extract
Epilobium angustifolium extract~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals and calm down irritation in skin. However, it can contain compounds that can be irritating themselves

More about Epilobium angustifolium extract
Sodium hyaluronate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Xanthan gum~0.25–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Sodium stearoyl glutamate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium stearoyl glutamate
Benzyl alcohol~0.2–0.35%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Ethylhexylglycerin~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Sodium benzoate~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Citric acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Sodium hydroxide~0.2–0.35%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Parfum~0.15–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ci 15985~0.2–0.35%
Irritant · high
Irritation risk
High

A colorant

More about Ci 15985
Ci 19140~0.15–0.3%
Irritant · high
Irritation risk
High

A yellow dye

More about Ci 19140
Geraniol~0.1–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Hexyl cinnamal~0.1–0.2%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Limonene~0.1–0.15%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Linalool~0.05–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Ingredient list view

Water, Aloe barbadensis leaf juice, Helianthus annuus seed oil, Caprylic/capric triglyceride, Cetearyl alcohol, Butyrospermum parkii butter, Glyceryl stearate citrate, Glycerin, Glyceryl stearate, Maltodextrin, Lactobacillus ferment, Palmitoyl tripeptide-5, Rubus chamaemorus fruit extract, Rubus idaeus fruit extract, Dipeptide diaminobutyroyl benzylamide diacetate, Salvia officinalis leaf extract, Origanum vulgare flower/leaf/stem extract, Thymus vulgaris extract, Acetum, Unknown, Ocimum basilicum leaf extract, Sus extract, Epilobium angustifolium extract, Sodium hyaluronate, Xanthan gum, Sodium stearoyl glutamate, Benzyl alcohol, Ethylhexylglycerin, Sodium benzoate, Potassium sorbate, Citric acid, Sodium hydroxide, Parfum, Ci 15985, Ci 19140, Geraniol, Hexyl cinnamal, Limonene, Linalool

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Cocoon Center
≈ $17.09
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Amazon UKPrice as of 10/3/2026 15:54 GMT
≈ $26.43
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Natura SibericaLab Biome Peptide Face CreamYOUR PRODUCTPacificaDreamy Youth Super Peptide CreamPeter Thomas RothFace Care Wrinkle Resist Eye CreamMEDI-PEELGold Age Tox H8 Cream
Match—61%60%59%
Price$17.09$16.53−$0.56$59.76+$42.67$20.25+$3.16
Shared key ingredients—5 of 85 of 86 of 8
Key difference—Isopropyl MyristateTripeptide-1Oligopeptide-1
Irritancy High Medium Medium High
Drying alcohol————
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Product summary

Judging from the ingredient list, "Natura Siberica - Lab Biome Peptide Face Cream" works well for improving skin hydration This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (glycerin, lactobacillus ferment, sodium hyaluronate and aloe barbadensis leaf juice) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Butyrospermum parkii butter, caprylic/capric triglyceride, helianthus annuus seed oil, cetearyl alcohol and glyceryl stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • This moisturizer also contains Peptides (dipeptide diaminobutyroyl benzylamide diacetate 0.40% - 0.60% and palmitoyl tripeptide-5 0.50% - 0.75%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Natura Siberica" is cruelty free and so is its parent company.

Price

The product retails for 12.93£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

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Natura Siberica Lab Biome Peptide Face Cream
Natura SibericaLab Biome Peptide Face Cream

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As an Amazon Associate, WIMJ earns from qualifying purchases.