NassifMD Dermaceuticals

NassifMD Dermaceuticals Age Defying Neck & Décolleté Serum

Name: NassifMD Dermaceuticals - Age Defying Neck & Décolleté Serum
Brand: NassifMD Dermaceuticals

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Niacinamide, Acetyl tetrapeptide-2 + 14 more

Works well

What the product description says

“A powerful serum formulated with Nassif MD’s proprietary Upfinity Peptide Complex TM specifically for the fragile neck and decollete area that is clinically proven to helps sagging skin appear firmer and more lifted helps skin tone look more even helps skin texture look and feel smoother and softer improves skin hydration reduces the appearance of lines & wrinkles helps skin appear more youthful and radiant”

Source: Nassif MD

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-2, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%

Acetyl tetrapeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~5.7–6.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.1%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~1.2–1.4%

PolymethylsilsesquioxaneKey activeEffect: HighA silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss~1–1.3%

Glyceryl glucosideKey active· HumectantEffect: HighCan help to restore skin barrier function and soften its upper layer~0.45–0.65%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.4–0.6%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.25–0.5%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.25–0.45%

Polysilicone-11Effect: LowA silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel~3.2–3.9%

Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~2.5–3%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.5–0.75%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.4–0.6%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.5%

Caprylic/capric triglycerideUnder-dosedA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.35–0.6%

Anti-aging

Niacinamide, Acetyl tetrapeptide-2 + 1 more

Works well

What the product description says

“Age Defying Neck & Décolleté Serum”

From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl tetrapeptide-2.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.4–1.8%

Acetyl tetrapeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%

Evens skin tone

Niacinamide

Works well

What the product description says

“A powerful serum formulated with Nassif MD’s proprietary Upfinity Peptide Complex TM specifically for the fragile neck and decollete area that is clinically proven to helps sagging skin appear firmer and more lifted helps skin tone look more even helps skin texture look and feel smoother and softer improves skin hydration reduces the appearance of lines & wrinkles helps skin appear more youthful and radiant”

Source: Nassif MD

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Anti-blemish

Not advertised by the brand · Niacinamide

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Can it cause trouble?

Irritancy

13 flagged ingredients — patch-test recommended

High risk

We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.25–0.45%est.

Citrus nobilis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.25–0.45%est.

Citrus paradisi peel oilUsed as a fragrance. Can be irritatingHigh~0.25–0.45%est.

Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.3–0.6%est.

AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.25–0.4%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.15–0.25%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.5–0.75%est.

EthylhexylglycerinA preservativeMedium~0.45–0.65%est.

Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.3–0.6%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.35–0.6%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.25–0.5%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.25–0.45%est.

Polysorbate 60Helps oil and water mix togetherMedium~0.2–0.4%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.25–0.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Dimethicone~5.7–6.9%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Hdi/ppg/polycaprolactone crosspolymer~4.5–5.4%

Formula

Irritation risk: Low

More about Hdi/ppg/polycaprolactone crosspolymer

Polysilicone-11~3.2–3.9%

Formula

Irritation risk: Low

Works for

MattifyingMoisturizing

A silicone that forms a light film on the skin surface helping to bind water and temporarily absorb oils creating a matt and powdery feel

More about Polysilicone-11

Isohexadecane~2.5–3%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane

Propanediol~2–2.4%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Glycerin~1.8–2.1%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Niacinamide~1.4–1.8%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Betaine~1.2–1.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Polymethylsilsesquioxane~1–1.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A silicone that improves product texture and helps dissolve other ingredients. Can form a non-greasy film on the skin to prevent moisture loss

More about Polymethylsilsesquioxane

Sodium mannose phosphate~0.65–1%

Formula

Irritation risk: Low

More about Sodium mannose phosphate

Mannose~0.55–0.85%

Formula

Irritation risk: Low

More about Mannose

Acetyl tetrapeptide-2~0.5–0.75%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl tetrapeptide-2

Caprylyl glycol~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Glyceryl glucoside~0.45–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

Can help to restore skin barrier function and soften its upper layer

More about Glyceryl glucoside

Phenoxyethanol~0.45–0.7%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Ethylhexylglycerin~0.45–0.65%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Sodium acrylates copolymer~0.3–0.6%

Irritant · medium

Irritation risk: Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer

Lecithin~0.4–0.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Squalane~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Polysorbate 20~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Caprylic/capric triglyceride~0.35–0.6%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Citrus aurantium dulcis peel oil~0.25–0.45%

Irritant · high

Irritation risk: High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil

Citrus nobilis peel oil~0.25–0.45%

Irritant · high

Irritation risk: High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus nobilis peel oil

Citrus paradisi peel oil~0.25–0.45%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Citrus paradisi peel oil

Silica~0.4–0.6%

Formula

Irritation risk: Low

Used to absorb oil and can temporarily mattify skin

More about Silica

Tocopherol~0.25–0.5%

Formula

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Glycine soja oil~0.25–0.5%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Hydroxyethylcellulose~0.25–0.5%

Formula

Irritation risk: Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose

Olea europaea fruit oil~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Decyl glucoside~0.3–0.6%

Irritant · high

Irritation risk: High

Works for

Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside

Sodium phytate~0.25–0.45%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Alcohol~0.25–0.4%

Irritant · high

Irritation risk: High

Works for

Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol

Mica~0.25–0.5%

Formula

Irritation risk: Low

Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light

More about Mica

Disodium phosphate~0.2–0.4%

Formula

Irritation risk: Low

Helps adjust the product pH and stabilize the formulation

More about Disodium phosphate

Sodium phosphate~0.2–0.4%

Formula

Irritation risk: Low

Helps stabilize the product formulation

More about Sodium phosphate

Polysorbate 60~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 60

Limonene~0.15–0.25%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Ci 77891~0.15–0.25%

Formula

Irritation risk: Low

More about Ci 77891

Titanium dioxide~0.15–0.3%

Formula

Irritation risk: Low

Works for

Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide

Ci 77891~0.1–0.2%

Formula

Irritation risk: Low

More about Ci 77891

Tin oxide~0.2–0.35%

Formula

Irritation risk: Low

A colorant that can add a pearl-like appearance to the formulation

More about Tin oxide

Ingredient list view

Water, Dimethicone, Hdi/ppg/polycaprolactone crosspolymer, Polysilicone-11, Isohexadecane, Propanediol, Glycerin, Niacinamide, Betaine, Polymethylsilsesquioxane, Sodium mannose phosphate, Mannose, Acetyl tetrapeptide-2, Caprylyl glycol, Glyceryl glucoside, Phenoxyethanol, Ethylhexylglycerin, Sodium acrylates copolymer, Lecithin, Squalane, Polysorbate 20, Caprylic/capric triglyceride, Citrus aurantium dulcis peel oil, Citrus nobilis peel oil, Citrus paradisi peel oil, Silica, Tocopherol, Glycine soja oil, Hydroxyethylcellulose, Olea europaea fruit oil, Decyl glucoside, Sodium phytate, Alcohol, Mica, Disodium phosphate, Sodium phosphate, Polysorbate 60, Limonene, Ci 77891, Titanium dioxide, Ci 77891, Tin oxide

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	NassifMD DermaceuticalsAge Defying Neck & Décolleté SerumYOUR PRODUCT	innisfreeGreen Tea PDRN™ Bounce Booster Eye & Lip Serum	mirenesseFast Fix Chin Tuck V Shape Lifting Serum	Marcelle2% Hyaluronic Acid + Probiotic Serum
Match	—	76%	76%	76%
Price	$60.00	$24.88−$35.12	—	$25.56−$34.44
Shared key ingredients	—	6 of 13	5 of 13	4 of 13
Key difference	—	Retinol	Acetyl Dipeptide-1 Cetyl Ester	Dimethiconol
Irritancy	High	Medium	Medium	Low
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"NassifMD Dermaceuticals - Age Defying Neck & Décolleté Serum" is effective for: Anti-blemish, Moisturizing, Anti-aging and Evens skin tone

Ingredient callouts

Peptides (acetyl tetrapeptide-2 0.50% - 0.75%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Humectants (glyceryl glucoside 0.45% - 0.65%, betaine 1.20% - 1.40% and glycerin 1.80% - 2.10%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.