Mesoestetic Stem Cell Nanofiller Lip Contour

Mesoestetic Stem Cell Nanofiller Lip Contour

Efficacy87/100IrritancyHigh
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Works for

2 of 2 advertised claims delivered

Moisturizing
14 ingredients credited for this claim
Strong support
What the product description says
“The solution is enriched with a healthy dose of Hyaluronic Acid, which delivers a plumping veil of moisture to the lips, whilst reducing the appearance of fine lines and creases around the mouth.”
Source: Lookfantastic Australia

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl pentapeptide-4, panthenol

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.7–8.2%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–0.85%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.75–1.15%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.2–0.35%
Malus domestica fruit extractKey activeEffect: HighHelps attract water to the upper layer of the skin~1.5–1.8%
Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.45–0.7%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.1–1.4%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~3.3–4%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~2.1–2.6%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.2–1.5%
Di-c12-13 alkyl malate· EmollientEffect: LowHelps soften the upper layer of the skin~0.65–0.95%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.4%
Anti-aging
2 ingredients credited for this claim
Moderate support
What the product description says
“MESOESTETIC STEM CELL NANOFILLER LIP CONTOUR CREAM 15mlThe first topical lip filler that uses plant Stem Cells and Hyaluronic Acid for the treatment of the delicate lip contour area.”
Source: Recreate Yourself

This product contains palmitoyl pentapeptide-4. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.4%
Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.45–0.7%

Can it cause trouble?

Irritancy
4 strong irritants: Retinyl palmitate, Parfum + 2 more — patch-test recommended
High risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.45–0.7%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.2–0.4%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.1–0.2%est.
MethylisothiazolinoneA preservative. Is a frequent allergenHigh~0.00075–0.0015%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.7–8.2%est.
Hydroxypropyl starch phosphateHelps oil and water mix together and used to stabilize product formulationsMedium~4–4.9%est.
Hydrogenated coco-glyceridesHelps oil and water mix together while creating a nice finish on the skinMedium~2.5–3%est.
Malus domestica fruit extractHelps attract water to the upper layer of the skinMedium~1.5–1.8%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.55–0.85%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.45–0.7%est.
Sodium metabisulfiteA preservativeMedium~0.1–0.2%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.1–1.4%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.7–8.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Hydroxypropyl starch phosphate~4–4.9%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together and used to stabilize product formulations

More about Hydroxypropyl starch phosphate
Cyclopentasiloxane~3.3–4%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Hydrogenated coco-glycerides~2.5–3%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together while creating a nice finish on the skin

More about Hydrogenated coco-glycerides
Isononyl isononanoate~2.1–2.6%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Glycerin~1.8–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Malus domestica fruit extract~1.5–1.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Helps attract water to the upper layer of the skin

More about Malus domestica fruit extract
Butylene glycol~1.2–1.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Cetearyl alcohol~1.1–1.4%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Glycerin~0.75–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Di-c12-13 alkyl malate~0.65–0.95%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Di-c12-13 alkyl malate
Cetearyl glucoside~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Dimethicone~0.55–0.85%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Panthenol~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Retinyl palmitate~0.45–0.7%
Under-dosedIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Tocopheryl acetate~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Carbomer~0.4–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Polysorbate 20~0.4–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sorbitan stearate~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Phenoxyethanol~0.3–0.55%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium metabisulfite~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sodium metabisulfite
Parfum~0.2–0.4%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Palmitoyl pentapeptide-4~0.25–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4
Xanthan gum~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Lecithin~0.25–0.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Helianthus annuus seed oil~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Rosmarinus officinalis leaf extract~0.1–0.2%
Irritant · high
Irritation risk
High
Works for
Anti-blemishAntibacterialAnti-oxidation

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Lactis proteinum~0.1–0.2%
Formula
Methylisothiazolinone~0.00075–0.0015%
Irritant · high
Irritation risk
High

A preservative. Is a frequent allergen

More about Methylisothiazolinone
Ingredient list view

Water, Caprylic/capric triglyceride, Hydroxypropyl starch phosphate, Cyclopentasiloxane, Hydrogenated coco-glycerides, Isononyl isononanoate, Glycerin, Malus domestica fruit extract, Butylene glycol, Cetearyl alcohol, Glycerin, Di-c12-13 alkyl malate, Cetearyl glucoside, Dimethicone, Panthenol, Retinyl palmitate, Tocopheryl acetate, Carbomer, Polysorbate 20, Sorbitan stearate, Phenoxyethanol, Sodium metabisulfite, Parfum, Disodium edta, Sodium hyaluronate, Palmitoyl pentapeptide-4, Xanthan gum, Lecithin, Helianthus annuus seed oil, Rosmarinus officinalis leaf extract, Lactis proteinum, Methylisothiazolinone

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Product summary

"Mesoestetic - Stem Cell Nanofiller Lip Contour" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Mesoestetic - Stem Cell Nanofiller Lip Contour ticks this box. Panthenol, glycerin, sodium hyaluronate and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (caprylic/capric triglyceride, dimethicone, helianthus annuus seed oil, cetearyl alcohol and cyclopentasiloxane) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • it includes a form of retinoids (vitamin A) - retinyl palmitate 0.45% - 0.70%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • We like that this moisturizer contains peptides (palmitoyl pentapeptide-4 0.25% - 0.40%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of it to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 121.40A$ up to 184.91A$ in Australia, for 101.65$ in the United States and from 60.00£ up to 64.99£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

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Mesoestetic Stem Cell Nanofiller Lip Contour
MesoesteticStem Cell Nanofiller Lip Contour

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