Mesoestetic Stem Cell Active Growth Factor

Mesoestetic Stem Cell Active Growth Factor

Efficacy62/100IrritancyHigh

Works for

Anti-aging
Retinyl palmitate, Palmitoyl oligopeptide + 2 more
May help
What the product description says
“Dexpanthenol stimulates activity in the fibroblast cells, boosting collagen and elastin production to firm the skin and target fine lines and wrinkles.”
Source: Face the future

This product contains palmitoyl oligopeptide, palmitoyl tetrapeptide-7, retinyl palmitate. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.5–0.8%
Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Anti-blemish
Retinyl palmitate, Rosmarinus officinalis leaf extract
Not delivered
What the product description says
“Suitable for daily use, the unique formula balances Plant Stem Cells and Epidermal Growth Factors, seeking to restructure skin from within the cell, stimulating skin’s natural repair function to minimise the appearance of blemishes, lines and imperfections.”
Source: Lookfantastic Australia

This product contains ingredients (retinyl palmitate) that could help reduce blemishes and clogged pores in theory, but there is not enough evidence that they actually work.

Retinyl palmitateEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.5–0.8%
Rosmarinus officinalis leaf extractUnder-dosedCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.3–0.55%
Moisturizing
Side benefit · Panthenol, Palmitoyl oligopeptide + 11 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, butylene glycol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: palmitoyl oligopeptide, palmitoyl tetrapeptide-7, panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.7–1.05%
Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.6–8%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~4.5–5.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.2–3.9%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.5–1.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.1–1.3%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.45–0.7%
Isononyl isononanoate· Emollient, OcclusiveEffect: LowForms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness~1.8–2.2%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.2–1.5%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.3–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Anti-oxidation
Side benefit · Dimethylmethoxy chromanol, Tocopheryl acetate + 2 more
Works well

This product contains antioxidants (dimethylmethoxy chromanol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Dimethylmethoxy chromanolKey activeEffect: HighCan help neutralize free radicals in skin~0.3–0.55%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.5–0.75%
Rosmarinus officinalis leaf extractEffect: Low, below effective doseCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating~0.3–0.55%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.45%
Evens skin tone
Side benefit · Retinyl palmitate
May help

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: retinyl palmitate.

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.5–0.8%

Can it cause trouble?

Irritancy
3 strong irritants: Retinyl palmitate, Rosmarinus officinalis leaf extract + 1 more — patch-test recommended
High risk
We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.5–0.8%est.
Rosmarinus officinalis leaf extractCan be helpful in reducing inflammation in skin, including inflamed acne. It can be irritatingHigh~0.3–0.55%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.25%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.6–8%est.
Hydroxypropyl starch phosphateHelps oil and water mix together and used to stabilize product formulationsMedium~2.4–3%est.
Hydrogenated coco-glyceridesHelps oil and water mix together while creating a nice finish on the skinMedium~2–2.5%est.
Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.6–0.9%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.5–0.75%est.
Disodium edtaStabilizes the product formulationMedium~0.35–0.65%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.5–1.9%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.6–8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cyclopentasiloxane~4.5–5.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Glycerin~3.2–3.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydroxypropyl starch phosphate~2.4–3%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together and used to stabilize product formulations

More about Hydroxypropyl starch phosphate
Hydrogenated coco-glycerides~2–2.5%
Irritant · medium
Irritation risk
Medium

Helps oil and water mix together while creating a nice finish on the skin

More about Hydrogenated coco-glycerides
Isononyl isononanoate~1.8–2.2%
Formula
Irritation risk
Low
Works for
Moisturizing

Forms a protective film on the surface of the skin to prevent moisture loss. Gives a velvety feel to products while reducing tackiness

More about Isononyl isononanoate
Cetearyl alcohol~1.5–1.9%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Butylene glycol~1.2–1.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Di-c12-12 alkyl malate
Not recognized
Dimethicone~1.1–1.3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Panthenol~0.7–1.05%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Cetearyl glucoside~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside
Retinyl palmitate~0.5–0.8%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Tocopheryl acetate~0.5–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Sorbitan stearate~0.45–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Malus domestica fruit cell culture extract~0.45–0.65%
Formula
Sodium metabisulfate
Not recognized
Helianthus annuus seed oil~0.45–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Disodium edta~0.35–0.65%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Rosmarinus officinalis leaf extract~0.3–0.55%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-blemishAnti-oxidationAntibacterial

Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating

More about Rosmarinus officinalis leaf extract
Dimethylmethoxy chromanol~0.3–0.55%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin

More about Dimethylmethoxy chromanol
Lactis proteinum~0.25–0.5%
Formula
Carbomer~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Xanthan gum~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Tocopherol~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Lecithin~0.3–0.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Palmitoyl oligopeptide~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide
Palmitoyl tetrapeptide-7~0.2–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Parfum~0.15–0.25%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Methylparaben~0.15–0.25%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Propylparaben~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Propylparaben
Ethylparaben~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Ethylparaben
Phenoxyethanol~0.1–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ingredient list view

Water, Caprylic/capric triglyceride, Cyclopentasiloxane, Glycerin, Hydroxypropyl starch phosphate, Hydrogenated coco-glycerides, Isononyl isononanoate, Cetearyl alcohol, Butylene glycol, Unknown, Dimethicone, Panthenol, Cetearyl glucoside, Retinyl palmitate, Tocopheryl acetate, Sorbitan stearate, Malus domestica fruit cell culture extract, Unknown, Helianthus annuus seed oil, Disodium edta, Rosmarinus officinalis leaf extract, Dimethylmethoxy chromanol, Lactis proteinum, Carbomer, Xanthan gum, Polysorbate 20, Tocopherol, Lecithin, Palmitoyl oligopeptide, Palmitoyl tetrapeptide-7, Parfum, Methylparaben, Propylparaben, Ethylparaben, Phenoxyethanol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MesoesteticStem Cell Active Growth FactorYOUR PRODUCTSkinMedicaTNS Ceramide Treatment CreamM-61Major Moisture!MEDI-PEELPeptide 9 Volume Tox Cream Pro
Match—61%58%58%
Price—$57.60—$26.33
Shared key ingredients—6 of 125 of 128 of 12
Key difference—Tetrahexyldecyl AscorbateAcetyl Tetrapeptide-11Acetyl Dipeptide-1 Cetyl Ester
Irritancy High Medium Medium Medium
Drying alcohol————
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Product summary

"Mesoestetic - Stem Cell Active Growth Factor" is effective for: Moisturizing

This product could be helpful for: Evens skin tone and Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • this product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.50% - 0.70%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • Peptides (palmitoyl tetrapeptide-7 0.20% - 0.40% and palmitoyl oligopeptide 0.30% - 0.55%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Panthenol (pro-vitamin B5) at about 0.60% - 0.85% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
  • Humectants (panthenol 0.60% - 0.85% and glycerin 3.20% - 3.90%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 72.99£ in the United Kingdom and for 140.00A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

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Mesoestetic Stem Cell Active Growth Factor
MesoesteticStem Cell Active Growth Factor

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