Meditopics

Meditopics Retinol Crème 1%

Name: Meditopics - Retinol Crème 1%
Brand: Meditopics

Efficacy100/100IrritancyHigh

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Works for

1 of 1 advertised claim delivered

Anti-aging

Retinol, Carnosine + 4 more

Strong evidence

What the product description says

“De combinatie van 0,5% retinol en 0,5% retinylpalmitaat bevordert de aanmaak van collageen en verfijnt de huidstructuur, waardoor de huid gladder en egaler oogt.”

Source: Huidpraktijk Shop

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine, hexanoyl dipeptide-3 norleucine acetate, retinyl palmitate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–0.85%

CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.25–0.5%

Hexanoyl dipeptide-3 norleucine acetateKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Retinyl palmitateKey activeEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.5–0.75%

NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.2–0.4%

Lactic acidUnder-dosedEffect: MediumAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.25–0.45%

Anti-oxidation

Not advertised by the brand · Carnosine, Retinol + 3 more

Strong evidence

This product contains antioxidants (carnosine, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.25–0.5%

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–0.85%

Calendula officinalis flower oilEffect: LowA plant oil that might have an antibacterial and some antioxidant effect. Is a common allergen and irritant~0.65–1%

Vitis vinifera seed oilEffect: LowA great emollient that can also have anti-oxidant properties~1.2–1.5%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.35–0.65%

Can it cause trouble?

Irritancy

5 strong irritants: Sodium anisate, Calendula officinalis flower oil + 3 more — patch-test recommended

High risk

We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Sodium anisateUsed as a fragranceHigh~1.6–2%est.

Calendula officinalis flower oilA plant oil that might have an antibacterial and some antioxidant effect. Is a common allergen and irritantHigh~0.65–1%est.

RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.55–0.85%est.

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.5–0.75%est.

Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~0.1–0.15%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.2–3.9%est.

Sodium levulinateA preservativeMedium~1.9–2.3%est.

Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~1.2–1.5%est.

Sodium stearoyl lactylateHelps oil and water mix togetherMedium~0.45–0.7%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.35–0.65%est.

Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.3–0.5%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.25–0.45%est.

EthylhexylglycerinA preservativeMedium~0.15–0.3%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.1%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.55–0.85%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glyceryl stearate citrate~5.4–6.6%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate

Glyceryl caprylate~3.5–4.3%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate

Caprylic/capric triglyceride~3.2–3.9%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Glycerin~2.4–3%

Formula

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Sodium levulinate~1.9–2.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sodium levulinate

Sodium anisate~1.6–2%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Sodium anisate

Glycerin~1.5–1.9%

Formula

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Vitis vinifera seed oil~1.2–1.5%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil

Brassica napus seed oil~1–1.2%

Formula

Irritation risk: Low

More about Brassica napus seed oil

Calendula officinalis flower oil~0.65–1%

Irritant · high

Irritation risk: High

Works for

Anti-oxidationAnti-inflammatory

A plant oil that might have an antibacterial and some antioxidant effect. Is a common allergen and irritant

More about Calendula officinalis flower oil

Retinol~0.55–0.85%

Hero · Anti-agingIrritant · high

Irritation risk: High

Works for

Anti-oxidationEvens skin toneAnti-blemishMattifyingExfoliationAnti-aging

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol

Retinyl palmitate~0.5–0.75%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-agingEvens skin toneAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Cetearyl alcohol~0.55–0.85%

Comedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Sodium stearoyl lactylate~0.45–0.7%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium stearoyl lactylate

Cetyl alcohol~0.5–0.75%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol

Vegetable oil~0.45–0.7%

Formula

Irritation risk: Low

Works for

Moisturizing

An oil from a mixture of different vegetables. Helps soften the upper layer of the skin

More about Vegetable oil

Tocopheryl acetate~0.35–0.65%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Glycine soja sterols~0.4–0.6%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps soften the skin

More about Glycine soja sterols

Sodium carboxymethyl betaglucan~0.3–0.55%

Formula

Irritation risk: Low

More about Sodium carboxymethyl betaglucan

Sodium lactate~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate

Carnosine~0.25–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine

Lactic acid~0.25–0.45%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Hexanoyl dipeptide-3 norleucine acetate~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexanoyl dipeptide-3 norleucine acetate

Lecithin~0.3–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Butylene glycol~0.25–0.45%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Panthenol~0.25–0.45%

Formula

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Calcium pantothenate~0.2–0.4%

Formula

Irritation risk: Low

Works for

Reduces irritationMoisturizing

Helps support skin barrier function improving skin hydration and reducing sensitivity

More about Calcium pantothenate

Niacinamide~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Inositol~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

More about Inositol

Phenoxyethanol~0.2–0.35%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Ethylhexylglycerin~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Glyceryl caprylate~0.2–0.35%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that can also help water and oil mix together, as well as prevent bacteria growth in products

More about Glyceryl caprylate

Xanthan gum~0.15–0.25%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Sodium phytate~0.1–0.2%

Formula

Irritation risk: Low

Used to stabilize product formulations

More about Sodium phytate

Alcohol denat.~0.1–0.15%

Irritant · high

Irritation risk: High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.

Citric acid~0.05–0.1%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Ingredient list view

Water, Glyceryl stearate citrate, Glyceryl caprylate, Caprylic/capric triglyceride, Glycerin, Sodium levulinate, Sodium anisate, Glycerin, Vitis vinifera seed oil, Brassica napus seed oil, Calendula officinalis flower oil, Retinol, Retinyl palmitate, Cetearyl alcohol, Sodium stearoyl lactylate, Cetyl alcohol, Vegetable oil, Tocopheryl acetate, Glycine soja sterols, Sodium carboxymethyl betaglucan, Sodium lactate, Carnosine, Lactic acid, Hexanoyl dipeptide-3 norleucine acetate, Lecithin, Butylene glycol, Panthenol, Calcium pantothenate, Niacinamide, Inositol, Phenoxyethanol, Ethylhexylglycerin, Glyceryl caprylate, Xanthan gum, Sodium phytate, Alcohol denat., Citric acid

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MeditopicsRetinol Crème 1%YOUR PRODUCT	innisfreeRetinol Cica Barrier Defense Cream	No7Pure Retinol 1% Night Concentrate	IOPEExpert Retinol RX™ 2% Reti-Jection Serum for Wrinkles
Match	—	81%	81%	77%
Price	$43.04	$4.88−$38.16	$42.99	$55.02+$11.98
Shared key ingredients	—	5 of 14	5 of 14	5 of 14
Key difference	—	Madecassoside	Acetyl Dipeptide-1 Cetyl Ester	Hydroxypinacolone Retinoate
Irritancy	High	Medium	Medium	Medium
Drying alcohol	Contains drying alcohol	—	—	—
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