Medik8 Niacinamide Peptides

Medik8 Niacinamide Peptides

Efficacy100/100IrritancyLow
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Works for

3 of 3 advertised claims delivered

Anti-blemish
2 ingredients credited for this claim
Strong support
What the product description says
“Pore Refining Clinically proven to help refine the appearance of pores and visibly improve skin texture.”
Source: Dermstore

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: zinc pca

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~5.6–6.9%
Zinc pcaKey activeEffect: MediumA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~1.5–1.8%
Anti-aging
5 ingredients credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains acetyl glucosamine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: carnosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~3.1–3.8%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~5.6–6.9%
CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~1.5–1.8%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Evens skin tone
2 ingredients credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: acetyl glucosamine, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~5.6–6.9%
Acetyl glucosamineKey activeEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~3.1–3.8%
Moisturizing
Not advertised by the brand · 14 ingredients credited for this claim
Strong support

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: carnosine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl glucosamine, niacinamide

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.8–2.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.1–2.5%
Acetyl glucosamineHero· HumectantEffect: HighAn effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin~3.1–3.8%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.2–5.2%
CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~5.6–6.9%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.95–1.15%
Zinc pcaKey active· HumectantEffect: HighA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~1.5–1.8%
Crambe abyssinica seed oilKey activeEffect: MediumHelps soften the upper layer of the skin~0.5–0.75%
Cetyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and is used to improve product texture and stability~0.25–0.5%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.5–0.75%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~2.4–2.9%
Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.5–0.75%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Anti-oxidation
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.15–0.3%
Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~1.5–1.8%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%

Can it cause trouble?

Irritancy
8 flagged ingredients
Low risk
We flag 8 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.2–5.2%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.55–0.8%est.
Crambe abyssinica seed oilHelps soften the upper layer of the skinMedium~0.5–0.75%est.
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.35–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.3–0.55%est.
EthylhexylglycerinA preservativeMedium~0.2–0.4%est.
Polysorbate 60Helps oil and water mix togetherMedium~0.15–0.25%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.5–0.75%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Niacinamide~5.6–6.9%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-blemishAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Caprylic/capric triglyceride~4.2–5.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Acetyl glucosamine~3.1–3.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingEvens skin toneAnti-agingExfoliation

An effective moisturizing ingredient that also has been shown to be effective in evening out the skin tone and reducing hyperpigmentation. It can help somewhat reduce wrinkles in skin

More about Acetyl glucosamine
Glyceryl stearate citrate~2.4–2.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Glycerin~2.1–2.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Dimethicone~1.8–2.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Zinc pca~1.5–1.8%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishAnti-agingAnti-oxidation

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca
Palmitoyl tetrapeptide-10~1.2–1.4%
Formula
Sodium hyaluronate~0.95–1.15%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Phenoxyethanol~0.65–0.95%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polyglyceryl-3 stearate~0.6–0.9%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polyglyceryl-3 stearate
Hydroxyacetophenone~0.55–0.8%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Crambe abyssinica seed oil~0.5–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Crambe abyssinica seed oil
Hydrogenated lecithin~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Behenyl alcohol~0.5–0.75%
Formula
Irritation risk
Low
Works for
Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol
Cetearyl alcohol~0.5–0.75%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.35–0.65%
Irritant · medium
Irritation risk
Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer
Disodium edta~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Xanthan gum~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Cetyl palmitate~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An emollient that helps soften the skin and is used to improve product texture and stability

More about Cetyl palmitate
Ethylhexylglycerin~0.2–0.4%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Carnosine~0.15–0.3%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine
Sorbitan stearate~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Polysorbate 80~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Polysorbate 60~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 60
Sorbitan isostearate~0.1–0.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan isostearate
Sodium benzoate~0.1–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Citric acid~0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Tocopherol~0.05–0.1%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ingredient list view

Water, Niacinamide, Caprylic/capric triglyceride, Acetyl glucosamine, Glyceryl stearate citrate, Glycerin, Dimethicone, Zinc pca, Palmitoyl tetrapeptide-10, Sodium hyaluronate, Phenoxyethanol, Polyglyceryl-3 stearate, Hydroxyacetophenone, Crambe abyssinica seed oil, Hydrogenated lecithin, Behenyl alcohol, Cetearyl alcohol, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Disodium edta, Xanthan gum, Cetyl palmitate, Ethylhexylglycerin, Carnosine, Sorbitan stearate, Polysorbate 80, Polysorbate 60, Sorbitan isostearate, Sodium benzoate, Citric acid, Tocopherol

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Amazon USPrice as of 10/12/2026 12:20 GMT
$56.00
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Dermstore
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Medik8Niacinamide PeptidesYOUR PRODUCTRohto MentholatumHada Labo Gokujyun Aging Care Firming CreamSwisse SkincareVitamin C 5% Niacinamide 5% Brightening Day CreamNeutrogenaUltra Gentle Face Gel Hydrator for Acne-Prone Skin
Match—82%82%81%
Price$56.00$20.07−$35.93$39.65−$16.35$14.99−$41.01
Shared key ingredients—5 of 84 of 84 of 8
Key difference—Hyaluronic AcidAscorbyl Glucoside—
Irritancy Low Low Low Low
Drying alcohol————
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Product summary

Judging from the ingredient list, "Medik8 - Niacinamide Peptides" works well for improving skin hydration This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Acetyl glucosamine, carnosine, glycerin, sodium hyaluronate and zinc pca in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Caprylic/capric triglyceride, dimethicone, cetearyl alcohol, cetyl palmitate and glyceryl stearate citrate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (5.60% - 6.90%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

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As an Amazon Associate, WIMJ earns from qualifying purchases.