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MediFlower Collagen Wrinkle Essence
MediFlower

MediFlower Collagen Wrinkle Essence

Efficacy87/100IrritancyHigh
See all ingredients

Works for

Anti-aging
Adenosine, Beta-glucan + 1 more
Works well
What the product description says
“Features Adenosine that helps reduce the appearance of wrinkles.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.05–0.3%
Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.25%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.05–0.25%
Moisturizing
Glycerin, Macadamia ternifolia seed oil + 15 more
Works
What the product description says
“A nourishing essence formulated with Hydrolyzed Collagen that helps enhance skin elasticity and keeps the skin moisturized.”
Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: betaine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, cetearyl alcohol.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.1–6.2%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~2.7–4.1%
BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~2–3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.3–1.9%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.45–1%
Glycosyl trehaloseKey activeEffect: High~0.15–0.7%
Hydrogenated starch hydrolysateKey active· HumectantEffect: MediumHelps to attract water to the upper layer of the skin. Can add sweet taste to lip products~0.15–0.55%
Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.05–0.25%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.05–0.25%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.05–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.4–5.1%
Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~1.7–2.5%
Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~0.45–1.05%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.75%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.1–0.35%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.05–0.25%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.6%

Can it cause trouble?

Irritancy
5 strong irritants: Illicium verum fruit extract, Parfum + 3 more — patch-test recommended
High risk
We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Panax ginseng root extractA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritatingHigh~0.15–0.55%est.
Illicium verum fruit extractAnise fruit extract. Used as a fragrance. Can be irritatingHigh~0.1–0.35%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.1–0.35%est.
Morus alba bark extractA plant extract that might have anti-oxidant properties and help even out skin tone, but solid evidence is lackingHigh~0.05–0.3%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.15%est.
CitronellolA fragrance. Can be irritatingHigh~0.01–0.1%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.01–0.05%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.01–0.05%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~2.7–4.1%est.
Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~1.7–2.5%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.75%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.25%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.05–0.25%est.
Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.05–0.25%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.1–0.3%est.
1,2-hexanediolA preservativeMedium~0.05–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.45–1%est.
Alternatives
Cheaper, or higher on efficacy
Miracle Age Repair Toner [EXP: 20-12-2023]
Thank You Farmer Miracle Age Repair Toner [EXP: 20-12-2023]
Higher efficacy · 100/10064% match
Aqua Wonder Moisture Toner
D'RAN Aqua Wonder Moisture Toner
Higher efficacy · 100/10063% match
$31.68
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.1–6.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~3.4–5.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Macadamia ternifolia seed oil~2.7–4.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Betaine~2–3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine
Cetyl ethylhexanoate~1.7–2.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate
Sodium acrylate/sodium acryloyldimethyl taurate copolymer~1.3–1.9%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer
Dimethicone~1.3–1.9%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Peg-400~1–1.45%
Formula
Irritation risk
Low
More about Peg-400
Polysorbate 20~0.6–1.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Hydrogenated polydecene~0.45–1.05%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene
Cetearyl alcohol~0.45–1%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Caprylyl glycol~0.2–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Glycosyl trehalose~0.15–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Glycosyl trehalose
Allantoin~0.15–0.6%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces rednessAnti-blemishReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Hydrolyzed collagen extract~0.15–0.65%
Formula
Irritation risk
Low
More about Hydrolyzed collagen extract
Hydrogenated starch hydrolysate~0.15–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin. Can add sweet taste to lip products

More about Hydrogenated starch hydrolysate
Panax ginseng root extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating

More about Panax ginseng root extract
Illicium verum fruit extract~0.1–0.35%
Irritant · high
Irritation risk
High

Anise fruit extract. Used as a fragrance. Can be irritating

More about Illicium verum fruit extract
Ammonium acryloyldimethyltaurate/vp copolymer~0.1–0.4%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Propylene glycol~0.1–0.35%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Xanthan gum~0.1–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Adenosine~0.05–0.3%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Laureth-8~0.1–0.35%
Formula
Irritation risk
Low
Works for
Cleansing
More about Laureth-8
Disodium edta~0.05–0.25%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Glyceryl acrylate/acrylic acid copolymer~0.05–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Glycyrrhiza glabra root extract~0.05–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatoryReduces rednessEvens skin toneAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract
Tocopheryl acetate~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Morus alba bark extract~0.05–0.3%
Irritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin tone

A plant extract that might have anti-oxidant properties and help even out skin tone, but solid evidence is lacking

More about Morus alba bark extract
Lilium candidum bulb extract~0.05–0.3%
Formula
Irritation risk
Low
More about Lilium candidum bulb extract
Beta-glucan~0.05–0.25%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationMoisturizingAnti-oxidationAnti-agingAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan
Camellia sinensis leaf extract~0.05–0.25%
Formula
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
1,2-hexanediol~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Parfum~0.05–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Citronellol~0.01–0.1%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Citronellol
Limonene~0.01–0.05%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Hexyl cinnamal~0.01–0.05%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Ingredient list view

Water, Glycerin, Butylene glycol, Macadamia ternifolia seed oil, Betaine, Cetyl ethylhexanoate, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Dimethicone, Peg-400, Polysorbate 20, Hydrogenated polydecene, Cetearyl alcohol, Chlorphenesin, Caprylyl glycol, Glycosyl trehalose, Allantoin, Hydrolyzed collagen extract, Hydrogenated starch hydrolysate, Panax ginseng root extract, Illicium verum fruit extract, Ammonium acryloyldimethyltaurate/vp copolymer, Propylene glycol, Xanthan gum, Adenosine, Laureth-8, Disodium edta, Glyceryl acrylate/acrylic acid copolymer, Glycyrrhiza glabra root extract, Tocopheryl acetate, Morus alba bark extract, Lilium candidum bulb extract, Beta-glucan, Camellia sinensis leaf extract, 1,2-hexanediol, Parfum, Citronellol, Limonene, Hexyl cinnamal

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MediFlowerCollagen Wrinkle EssenceYOUR PRODUCTThank You FarmerMiracle Age Repair Toner [EXP: 20-12-2023]D'RANAqua Wonder Moisture TonerMEDI-PEELAll In One Peptide 9 Volume Essence
Match—64%63%63%
Price$15.22—$31.68+$16.46$26.28+$11.06
Shared key ingredients—5 of 86 of 85 of 8
Key difference—NiacinamideNiacinamideNiacinamide
Irritancy High Medium Medium Medium
Drying alcohol—— Contains drying alcohol —
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Product summary

"MediFlower - Collagen Wrinkle Essence" is effective for: Anti-aging

This product could be helpful for: Moisturizing, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Adenosine 0.05% - 0.30%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Humectants (glyceryl acrylate/acrylic acid copolymer 0.05% - 0.25%, betaine 2.00% - 3.00% and glycerin 4.10% - 6.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 17.70$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 24 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Fatty acids profile of oil from nine varieties of Macadamia nuttandfonline.com
  3. 3
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  4. 4
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  5. 5
    Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
  6. 6
    Profile of wound healing process induced by allantoinscielo.br
MediFlower Collagen Wrinkle Essence
MediFlowerCollagen Wrinkle Essence
Buy at Yesstyle$15.22Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Yesstyle$15.22Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.