What's In My Jar
Medicube EGF NAD Firming Serum
Medicube

Medicube EGF NAD Firming Serum

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Niacinamide, Adenosine + 10 more
Works well
What the product description says
“This non-comedogenic, anti-aging formula harnesses the power of EGF and NAD+ to help restore skin vitality and visibly smooth fine lines.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-1, acetyl octapeptide-3, copper tripeptide-1, folic acid, hexapeptide-11, oligopeptide-1, oligopeptide-3, palmitoyl tripeptide-5, sh-oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.3–4%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Acetyl octapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.2–0.35%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Acetyl hexapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.25%
Oligopeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Hexapeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
Oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
Moisturizing
Niacinamide, Acetyl dipeptide-1 cetyl ester + 22 more
Works well
What the product description says
“Collagen, peptides, niacinamide and adenosine also play a part in boosting hydration, improving elasticity and enhancing radiance while remaining gentle on skin.”
Source: Yesstyle

This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": anhydroxylitol, glycerin.

When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester, acetyl hexapeptide-1, acetyl octapeptide-3, copper tripeptide-1, hexapeptide-11, niacinamide, oligopeptide-1, oligopeptide-3, palmitoyl tripeptide-5, sh-oligopeptide-1

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.3–4%
Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Acetyl hexapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Acetyl octapeptide-3Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.25%
Oligopeptide-3HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.25%
Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.15–0.3%
Hexapeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
Oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.1%
EctoinKey activeEffect: HighSoftens the upper layer of the skin and can support skin barrier function~1.3–1.6%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.2–0.35%
CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.2–0.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.35%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.15–0.25%
AnhydroxylitolKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrir function~0.15–0.25%
XylitylglucosideKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and repair the skin barrier function~0.15–0.25%
Ulmus davidiana root extractKey activeEffect: MediumA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin~0.15–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~6.4–7.8%
Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.3–0.6%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.35%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.35%
Rosa canina fruit oilUnder-dosedA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating~0.2–0.35%
Evens skin tone
Niacinamide, Glutathione
Works well
What the product description says
“Niacinamide helps brighten dullness, while hyaluronic acid delivers a dose of hydration for skin that feels comfortable and looks refreshed.”
Source: Cultbeauty

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.3–4%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.15–0.25%
Anti-blemish
Side benefit · Niacinamide
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.3–4%
Anti-oxidation
Side benefit · Glutathione, Ficus carica fruit extract + 11 more
Works well

This product contains antioxidants (glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - ficus carica fruit extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.15–0.25%
Ficus carica fruit extractKey activeEffect: MediumA plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect~0.15–0.3%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Euterpe oleracea fruit extractEffect: LowA plant extract that can have some anti-oxidant effect in skin~0.2–0.35%
Sambucus nigra fruit extractEffect: LowA plant extract that may contain a small amount of essential oils. Might be helpful in neutralizing free radicals in skin~0.2–0.35%
Vaccinium macrocarpon fruit extractEffect: LowA berry extract. Might have some anti-oxidant properties~0.2–0.35%
Hibiscus sabdariffa flower extractEffect: LowA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals~0.2–0.35%
Vaccinium myrtillus fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking~0.15–0.3%
Rubus fruticosus fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin~0.15–0.3%
Ulmus davidiana root extractEffect: LowA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin~0.15–0.3%
Vaccinium angustifolium fruit extractEffect: LowA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking~0.15–0.3%
Rubus idaeus fruit extractEffect: LowA fruit extract that might have some anti-oxidant properties but evidence of effectiveness in skin is lacking~0.15–0.3%
Rosa canina fruit oilEffect: Low, below effective doseA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating~0.2–0.35%

Can it cause trouble?

Irritancy
2 strong irritants: Oenothera biennis flower extract, Hibiscus sabdariffa flower extract
Medium risk
We flagged 20 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Vaccinium macrocarpon fruit extractA berry extract. Might have some anti-oxidant propertiesHigh~0.2–0.35%est.
Ulmus davidiana root extractA plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skinHigh~0.15–0.3%est.
Sambucus nigra fruit extractA plant extract that may contain a small amount of essential oils. Might be helpful in neutralizing free radicals in skinHigh~0.2–0.35%est.
Oenothera biennis flower extractUsed as a fragranceHigh~0.2–0.35%est.
Hibiscus sabdariffa flower extractA plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicalsHigh~0.2–0.35%est.
1,2-hexanediolA preservativeMedium~0.9–1.1%est.
EthylhexylglycerinA preservativeMedium~0.45–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Hydrogenated phosphatidylcholineHelps oil and water mix togetherMedium~0.2–0.35%est.
Rosa canina fruit oilA great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritatingMedium~0.2–0.35%est.
Sorbitan laurateHelps water and oil mix togetherMedium~0.15–0.3%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.35%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.15–0.3%est.
Vaccinium myrtillus fruit extractA plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lackingMedium~0.15–0.3%est.
Vaccinium angustifolium fruit extractA plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lackingMedium~0.15–0.3%est.
Rubus idaeus fruit extractA fruit extract that might have some anti-oxidant properties but evidence of effectiveness in skin is lackingMedium~0.15–0.3%est.
Rubus fruticosus fruit extractA plant extract that might help neutralize free radicals in skinMedium~0.15–0.3%est.
Euterpe oleracea fruit extractA plant extract that can have some anti-oxidant effect in skinMedium~0.2–0.35%est.
Ficus carica fruit extractA plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effectMedium~0.15–0.3%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.15–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Theobroma cacao seed extract—3/5~0.3–0.6%est.
Alternatives
Cheaper, or higher on efficacy
TXA Niacinamide Toning Shot 99 Serum
APRIL SKIN TXA Niacinamide Toning Shot 99 Serum
Cheaper74% match
$16.93
Peptide 9 Aqua Essence Lifting Ampoule
MEDI-PEEL Peptide 9 Aqua Essence Lifting Ampoule
Cheaper72% match
$13.28
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Butylene glycol~6.4–7.8%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dipropylene glycol~4.8–5.8%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Niacinamide~3.3–4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Xylitol~2.4–2.9%
Formula
Irritation risk
Low

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitol
1,2-hexanediol~0.9–1.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Glycereth-26~1.6–1.9%
Formula
Irritation risk
Low

Helps create a thicker product consistency

More about Glycereth-26
Ectoin~1.3–1.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Softens the upper layer of the skin and can support skin barrier function

More about Ectoin
Carbomer~1.1–1.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
C12-14 alketh-12~0.7–1.1%
Formula
Irritation risk
Low
More about C12-14 alketh-12
Tromethamine~0.5–0.75%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Ethylhexylglycerin~0.45–0.65%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Theobroma cacao seed extract~0.3–0.6%
Comedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
More about Theobroma cacao seed extract
Dextrin~0.3–0.6%
Formula
Irritation risk
Low
Works for
Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin
Adenosine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Methyl diisopropyl propionamide~0.25–0.45%
Formula
Irritation risk
Low
More about Methyl diisopropyl propionamide
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Cyanocobalamin~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin
Hydrogenated phosphatidylcholine~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Hydrogenated phosphatidylcholine
Sh-oligopeptide-1~0.15–0.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1
Glycerin~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Rosa canina fruit oil~0.2–0.35%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient. Contains vitamin E (tocopherol) which may give it some anti-oxidant properties. Can contain volatile compounds and can be irritating

More about Rosa canina fruit oil
Nicotinamide adenine dinucleotide~0.1–0.25%
Formula
Irritation risk
Low
More about Nicotinamide adenine dinucleotide
Xylitylglucoside~0.15–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrier function

More about Xylitylglucoside
Anhydroxylitol~0.15–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and repair the skin barrir function

More about Anhydroxylitol
Sorbitan laurate~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan laurate
Lecithin~0.2–0.35%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Caprylyl glycol~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Polyglyceryl-10 laurate~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Hydroxyethylcellulose~0.2–0.35%
Formula
Irritation risk
Low

Used to thicken product formulations and create gel-like textures

More about Hydroxyethylcellulose
Acetyl glutamine~0.15–0.3%
Formula
Irritation risk
Low
More about Acetyl glutamine
Acetyl dipeptide-1 cetyl ester~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatoryAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Hydrogenated lecithin~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Bacillus/soybean ferment extract~0.15–0.3%
Formula
Irritation risk
Low
More about Bacillus/soybean ferment extract
Vaccinium vitis-idaea fruit extract~0.2–0.35%
Formula
Irritation risk
Low
More about Vaccinium vitis-idaea fruit extract
Vaccinium myrtillus fruit extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its efficacy in skin is lacking

More about Vaccinium myrtillus fruit extract
Vaccinium macrocarpon fruit extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A berry extract. Might have some anti-oxidant properties

More about Vaccinium macrocarpon fruit extract
Vaccinium angustifolium fruit extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract tha can have anti-oxidant properties, but evidence of effectiveness in skin is lacking

More about Vaccinium angustifolium fruit extract
Ulmus davidiana root extract~0.15–0.3%
Key activeIrritant · high
Irritation risk
High
Works for
MoisturizingAnti-oxidation

A plant root extract that helps attract water to the upper layer of the skin. It might have an anti-inflammatory effect and could help neturalize free radicals in skin

More about Ulmus davidiana root extract
Sambucus nigra fruit extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that may contain a small amount of essential oils. Might be helpful in neutralizing free radicals in skin

More about Sambucus nigra fruit extract
Rubus idaeus fruit extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A fruit extract that might have some anti-oxidant properties but evidence of effectiveness in skin is lacking

More about Rubus idaeus fruit extract
Rubus fruticosus fruit extract~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might help neutralize free radicals in skin

More about Rubus fruticosus fruit extract
Pueraria lobata root extract~0.2–0.35%
Formula
Irritation risk
Low
More about Pueraria lobata root extract
Pinus palustris leaf extract~0.2–0.35%
Formula
Irritation risk
Low
More about Pinus palustris leaf extract
Oenothera biennis flower extract~0.2–0.35%
Irritant · high
Irritation risk
High

Used as a fragrance

More about Oenothera biennis flower extract
Euterpe oleracea fruit extract~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can have some anti-oxidant effect in skin

More about Euterpe oleracea fruit extract
Collagen extract~0.2–0.35%
Formula
Irritation risk
Low
More about Collagen extract
Palmitoyl tripeptide-5~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Hibiscus sabdariffa flower extract~0.2–0.35%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that can be irritating. It might contain a compound anthocyanin that could be helpful in neutralizing free radicals

More about Hibiscus sabdariffa flower extract
Acetyl hexapeptide-1~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-1
Acetyl octapeptide-3~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl octapeptide-3
Sodium hyaluronate~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Folic acid~0.2–0.35%
Key active
Irritation risk
Low
Works for
Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid
Ficus carica fruit extract~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect

More about Ficus carica fruit extract
Glutathione~0.15–0.25%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationMoisturizingEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Copper tripeptide-1~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1
Oligopeptide-3~0.15–0.25%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Oligopeptide-3
Oligopeptide-2~0.1–0.2%
Formula
Irritation risk
Low
More about Oligopeptide-2
Oligopeptide-1~0.05–0.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Oligopeptide-1
Hexapeptide-11~0.05–0.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Hexapeptide-11
Ingredient list view

Water, Butylene glycol, Dipropylene glycol, Niacinamide, Xylitol, 1,2-hexanediol, Glycereth-26, Ectoin, Carbomer, C12-14 alketh-12, Tromethamine, Ethylhexylglycerin, Theobroma cacao seed extract, Dextrin, Adenosine, Methyl diisopropyl propionamide, Disodium edta, Cyanocobalamin, Hydrogenated phosphatidylcholine, Sh-oligopeptide-1, Glycerin, Rosa canina fruit oil, Nicotinamide adenine dinucleotide, Xylitylglucoside, Anhydroxylitol, Sorbitan laurate, Lecithin, Caprylyl glycol, Polyglyceryl-10 laurate, Hydroxyethylcellulose, Acetyl glutamine, Acetyl dipeptide-1 cetyl ester, Hydrogenated lecithin, Bacillus/soybean ferment extract, Vaccinium vitis-idaea fruit extract, Vaccinium myrtillus fruit extract, Vaccinium macrocarpon fruit extract, Vaccinium angustifolium fruit extract, Ulmus davidiana root extract, Sambucus nigra fruit extract, Rubus idaeus fruit extract, Rubus fruticosus fruit extract, Pueraria lobata root extract, Pinus palustris leaf extract, Oenothera biennis flower extract, Euterpe oleracea fruit extract, Collagen extract, Palmitoyl tripeptide-5, Hibiscus sabdariffa flower extract, Acetyl hexapeptide-1, Acetyl octapeptide-3, Sodium hyaluronate, Folic acid, Ficus carica fruit extract, Glutathione, Copper tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MedicubeEGF NAD Firming SerumYOUR PRODUCTHanskinCollagen Peptide Hydra AmpoulenumbuzinNo.2 Rose PDRN Collagen 2x Plumping SerumCOSRXThe Blue Peptide Bakuchiol Plump Glow Serum
Match—74%74%74%
Price$22.90$22.40−$0.50$21.00−$1.90$19.99−$2.91
Shared key ingredients—9 of 209 of 207 of 20
Key difference—Pentapeptide-18Sh-Polypeptide-22Bakuchiol
Irritancy Medium Medium Medium Medium
Drying alcohol——— Contains drying alcohol
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 34 studies and safety reviews.

  1. 1
    Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
  2. 2
    Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
  3. 3
    The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
  4. 4
    Safety Assessment of Glycerin Ethoxylates as Used in Cosmeticscir-safety.org
  5. 5
    Safety Assessment of Tromethamine as Used in Cosmeticscir-safety.org
  6. 6
    Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
Medicube EGF NAD Firming Serum
MedicubeEGF NAD Firming Serum
Buy at Yesstyle$22.90Amazon

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Buy at Yesstyle$22.90Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.