Medicube Azelaic Acid Exosome Shot 2000

Medicube Azelaic Acid Exosome Shot 2000

Efficacy100/100IrritancyMedium

Works for

Moisturizing
Niacinamide, Ceramide np + 17 more
Works well
What the product description says
“After absorption, apply a moisturising formula to finish skincare routine.”
Source: Lila Beauty

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glyceryl acrylate/acrylic acid copolymer.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: phenyl trimethicone, hydrolyzed collagen.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.7%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%
Phenyl trimethiconeKey active· OcclusiveEffect: HighA type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture~0.7–1.1%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.3–0.55%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.25–0.5%
Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.25–0.5%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%
Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.2–0.4%
Pantothenic acidKey activeEffect: HighHelps attract water to the upper layer of the skin and may help reduce inflammation in skin~0.2–0.4%
CollagenKey activeEffect: MediumCannot penetrate the skin barrier so is not particularly useful in skincare products~0.2–0.4%
Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.3%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.3%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.3%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~6–7.3%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~1.3–1.6%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.15–0.25%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%
Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.4%
Anti-aging
Side benefit · Niacinamide, Adenosine + 2 more
Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: asiaticoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.7%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.3%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%
Anti-oxidation
Side benefit · Azelaic acid, Asiaticoside + 8 more
Works well

This product contains antioxidants (asiaticoside, azelaic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Azelaic acidKey activeEffect: HighIs produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals~0.25–0.4%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.15–0.3%
Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.3–0.6%
Aloe barbadensis flower extractEffect: LowA plant extract that might have some anti-oxidant effect~0.25–0.45%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Coccinia indica fruit extractEffect: LowA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin~0.25–0.5%
Solanum melongena fruit extractEffect: LowEggplant fruit extract. Might have some anti-oxidant effect~0.2–0.4%
Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.2–0.4%
Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.2–0.4%
Centella asiatica extractUnder-dosedA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%
Exfoliation
Side benefit · Betaine salicylate, Azelaic acid + 1 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: betaine salicylate.

Betaine salicylateKey activeEffect: HighExfoliating acid, a "relative" of salicylic acid~0.25–0.4%
Azelaic acidKey activeEffect: MediumIs produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals~0.25–0.4%
Salicylic acidUnder-dosedUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.25%
Evens skin tone
Side benefit · Niacinamide, Azelaic acid + 2 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: azelaic acid, betaine salicylate, niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.7%
Azelaic acidKey activeEffect: HighIs produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals~0.25–0.4%
Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.2–0.4%
Salicylic acidEffect: Low, below effective doseUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.25%
Anti-blemish
Side benefit · Niacinamide, Azelaic acid + 5 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: azelaic acid, niacinamide. These ingredients is used for treating acne and can have a noticeable effect.

In addition, this product contains betaine salicylate. It can help in reducing blemishes, even though it is less effective.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: pantothenic acid

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3.1–3.7%
Azelaic acidHeroEffect: HighIs produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals~0.25–0.4%
Betaine salicylateKey activeEffect: HighExfoliating acid, a "relative" of salicylic acid~0.25–0.4%
Pantothenic acidKey activeEffect: MediumHelps attract water to the upper layer of the skin and may help reduce inflammation in skin~0.2–0.4%
Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.4–0.6%
Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.25–0.5%
Salicylic acidUnder-dosedUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)~0.15–0.25%

Can it cause trouble?

Irritancy
1 strong irritant: Ocimum sanctum leaf extract
Medium risk
We flagged 19 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.4–0.6%est.
Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.2–0.4%est.
Aloe barbadensis flower extractA plant extract that might have some anti-oxidant effectHigh~0.25–0.45%est.
Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.2–0.4%est.
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High~0.15–0.25%est.
1,2-hexanediolA preservativeMedium~0.65–0.95%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~1.3–1.6%est.
Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.3–0.6%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.3–0.55%est.
EthylhexylglycerinA preservativeMedium~0.3–0.55%est.
Coccinia indica fruit extractA plant extract that might have some anti-oxidant effect helping neutralize free radicals in skinMedium~0.25–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Solanum melongena fruit extractEggplant fruit extract. Might have some anti-oxidant effectMedium~0.2–0.4%est.
Betaine salicylateExfoliating acid, a "relative" of salicylic acidMedium~0.25–0.4%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.2–0.4%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.25–0.5%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.15–0.3%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.15–0.3%est.
Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.15–0.3%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.2–0.4%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Butylene glycol~6–7.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dipropylene glycol~4.2–5.2%
Formula
Irritation risk
Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol
Niacinamide~3.1–3.7%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Glycerin~2.3–2.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Sodium polyacrylate~1.9–2.4%
Formula
Irritation risk
Low
Works for
Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate
1,2-hexanediol~0.65–0.95%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~1.3–1.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Cetearyl olivate~1–1.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Phenyl trimethicone~0.7–1.1%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture

More about Phenyl trimethicone
Sorbitan olivate~0.55–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Hydrolyzed sponge~0.45–0.7%
Formula
Melia azadirachta leaf extract~0.4–0.6%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract
Melia azadirachta flower extract~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract
Glyceryl acrylate/acrylic acid copolymer~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Ethylhexylglycerin~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Calcium aluminum borosilicate~0.3–0.6%
Formula
Irritation risk
Low

Used to thickenthe product consistency

More about Calcium aluminum borosilicate
Coccinia indica fruit extract~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect helping neutralize free radicals in skin

More about Coccinia indica fruit extract
Adenosine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Pvim/ma copolymer
Not recognized
Ocimum sanctum leaf extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract
Solanum melongena fruit extract~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Eggplant fruit extract. Might have some anti-oxidant effect

More about Solanum melongena fruit extract
Aloe barbadensis flower extract~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant effect

More about Aloe barbadensis flower extract
Dipotassium glycyrrhizate~0.2–0.4%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Azelaic acid~0.25–0.4%
Hero · Anti-blemish
Irritation risk
Low
Works for
Anti-blemishAnti-oxidationEvens skin toneExfoliation

Is produced by a yeast that lives on normal human skin. It is used in medicine as a topical treatment for mild to moderate acne. It has a mild exfoliating effect. It can also help reduce hyperpigmentation, helps calm down inflammation and can help neutralize free radicals

More about Azelaic acid
Curcuma longa root extract~0.2–0.4%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract
Corallina officinalis extract~0.2–0.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract
Lactobacillus extracellular vesicles~0.2–0.35%
Formula
Isopentyldiol~0.25–0.4%
Formula
Irritation risk
Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol
Betaine salicylate~0.25–0.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-blemishExfoliation

Exfoliating acid, a "relative" of salicylic acid

More about Betaine salicylate
Citric acid~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Pantothenic acid~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-blemishReduces redness

Helps attract water to the upper layer of the skin and may help reduce inflammation in skin

More about Pantothenic acid
Milk exosomes~0.25–0.45%
Formula
Irritation risk
Low
More about Milk exosomes
Propanediol~0.25–0.45%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Glycerin~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydrolyzed collagen~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen
Sodium hyaluronate~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Collagen~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Cannot penetrate the skin barrier so is not particularly useful in skincare products

More about Collagen
Centella asiatica extract~0.25–0.5%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Asiaticoside~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-agingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Madecassic acid~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Ceramide np~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Asiatic acid~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryReduces irritationMoisturizing

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid
Sorbitan stearate~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Sorbitan stearate
Palmitic acid~0.15–0.25%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Salicylic acid~0.15–0.25%
Under-dosedIrritant · high
Irritation risk
High
Works for
ExfoliationAnti-inflammatoryAnti-blemishAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Ingredient list view

Water, Butylene glycol, Dipropylene glycol, Niacinamide, Glycerin, Sodium polyacrylate, 1,2-hexanediol, Caprylyl glycol, Cetearyl olivate, Phenyl trimethicone, Sorbitan olivate, Hydrolyzed sponge, Melia azadirachta leaf extract, Melia azadirachta flower extract, Glyceryl acrylate/acrylic acid copolymer, Ethylhexylglycerin, Calcium aluminum borosilicate, Coccinia indica fruit extract, Adenosine, Disodium edta, Unknown, Ocimum sanctum leaf extract, Solanum melongena fruit extract, Aloe barbadensis flower extract, Dipotassium glycyrrhizate, Azelaic acid, Curcuma longa root extract, Corallina officinalis extract, Lactobacillus extracellular vesicles, Isopentyldiol, Betaine salicylate, Citric acid, Pantothenic acid, Milk exosomes, Propanediol, Glycerin, Hydrolyzed collagen, Sodium hyaluronate, Collagen, Centella asiatica extract, Asiaticoside, Madecassic acid, Ceramide np, Asiatic acid, Sorbitan stearate, Palmitic acid, Salicylic acid

Compare prices

Retailers ranked by price — lowest first.

🇦🇺 Lila Beauty (AU)30 ml
≈ $23.78
Buy
🇬🇧 Amazon UK (UK)Price as of 11/6 18:00 GMT
≈ $26.44
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
MedicubeAzelaic Acid Exosome Shot 2000YOUR PRODUCTskinmadeAzelaic Acid + Salicylic Acid serumTulaAcne Clearing + Tone Correcting GelinnisfreeGentle Retinol Salicylic Acne Serum
Match—76%70%69%
Price———$34.00
Shared key ingredients—8 of 206 of 208 of 20
Key difference—Potassium Azeloyl DiglycinateLactic AcidRetinol
Irritancy Medium Medium Low Medium
Drying alcohol————
View product Shop Shop Shop

More alternatives: Some By Mi Charcoal BHA Pore Clay Bubble MaskSCINIC Hyaluronic Acid Soothing Stick

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Product summary

"Medicube - Buy Medicube Azelaic Acid Exosome Shot 2000" is effective for: Moisturizing, Anti-aging, Exfoliation, Evens skin tone and Anti-blemish

Ingredient callouts

  • A good concentration of Niacinamide (3.10% - 3.70%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
  • Ceramides (ceramide np 0.20% - 0.35%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - asiatic acid 0.15% - 0.30%, madecassic acid 0.15% - 0.30% and asiaticoside 0.15% - 0.30% The Centella Asiatica Actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
  • Humectants (sodium hyaluronate 0.20% - 0.40%, hydrolyzed collagen 0.25% - 0.50%, glycerin 0.25% - 0.50%, glyceryl acrylate/acrylic acid copolymer 0.30% - 0.55% and glycerin 2.30% - 2.90%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 35.04A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

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    Melia azedarachmdedge.com
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Medicube Azelaic Acid Exosome Shot 2000
MedicubeAzelaic Acid Exosome Shot 2000

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As an Amazon Associate, WIMJ earns from qualifying purchases.