MEDI-PEEL

MEDI-PEEL Peptide 9 Hyaluronic Volumy Eye Cream

Name: MEDI-PEEL - Peptide 9 Hyaluronic Volumy Eye Cream
Brand: MEDI-PEEL

Efficacy100/100IrritancyHigh

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Works for

2 of 2 advertised claims delivered

Anti-aging

Adenosine, Niacinamide + 11 more

Strong evidence

What the product description says

“Medi-Peel Peptide 9 Hyaluronic Volumy Eye Cream helps to hydrate skin and improve skin elasticity.”

Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, copper tripeptide-1, oligopeptide-32, palmitoyl oligopeptide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%

Copper tripeptide-1Key activeEffect: MediumA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.3%

Oligopeptide-32Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Palmitoyl oligopeptideKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl pentapeptide-4Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.5%

Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.55–0.8%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.6%

Moisturizing

Niacinamide, Oligopeptide-32 + 33 more

Strong evidence

What the product description says

“Peptide 9 Hyaluronic Volumy Eye Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, copper tripeptide-1, niacinamide, oligopeptide-32, palmitoyl oligopeptide, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.3–0.55%

Sodium hyaluronate crosspolymerKey active· HumectantEffect: HighAttracts water into the upper layer of the skin~0.3–0.55%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.4–0.6%

Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.5%

Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.35–0.65%

Hydrolyzed glycosaminoglycansKey active· HumectantEffect: HighLong sugars that help attract water to the upper layer of the skin~0.3–0.55%

Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.3–0.55%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.3%

Oligopeptide-32HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.2%

Palmitoyl oligopeptideHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%

Palmitoyl pentapeptide-4HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.1–0.15%

Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%

Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.5%

TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.3–0.55%

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.3–0.55%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.3–5.2%

Copper tripeptide-1HeroEffect: HighA naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.~0.15–0.3%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.4–2.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3–3.7%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.3–0.6%

CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.5–1.8%

Porphyridium cruentum extractKey activeEffect: MediumA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect~0.3–0.55%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1.3–1.5%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.3–0.55%

Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.35–0.6%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.6–0.85%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.55%

Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.45–0.7%

Glyceryl polymethacrylate· Humectant, EmollientEffect: LowUsed to create a nice product texture~0.35–0.6%

Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.55–0.8%

CyclohexasiloxaneEffect: Low, below effective doseA silicone that serves as an emollient. Helps create a nice non-greasy feels~0.75–1.1%

Evens skin tone

Not advertised by the brand · Niacinamide, Glycyrrhiza glabra root extract

Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.3–0.5%

Anti-oxidation

Not advertised by the brand · Ginkgo biloba leaf extract, Anemarrhena asphodeloides root extract + 8 more

Moderate evidence

This product contains antioxidants (ginkgo biloba leaf extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Ginkgo biloba leaf extractKey activeEffect: MediumA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating~0.3–0.55%

Anemarrhena asphodeloides root extractEffect: LowA plant extract that might have some anti-oxidant properties~0.2–0.4%

Zanthoxylum piperitum fruit extractEffect: LowPlant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell~0.3–0.55%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.3–0.5%

Juniperus communis fruit extractEffect: LowBerry extract that might have some anti-oxidant effect~0.25–0.5%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.55%

Porphyridium cruentum extractEffect: LowA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect~0.3–0.55%

Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.25–0.5%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.6%

Can it cause trouble?

Irritancy

4 strong irritants: Eucalyptus globulus leaf extract, Parfum + 2 more — patch-test recommended

High risk

We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.45–0.7%est.

Eucalyptus globulus leaf extractUsed as a fragrance. Can be irritatingHigh~0.25–0.5%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.3–0.55%est.

Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.3–0.55%est.

Rosa damascena flower extractUsed as a fragrance. Can be irritatingHigh~0.3–0.55%est.

Ginkgo biloba leaf extractA plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritatingHigh~0.3–0.55%est.

Zanthoxylum piperitum fruit extractPlant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smellHigh~0.3–0.55%est.

Raspberry ketoneUsed as a fragrance. It can reduce skin pigmentation, but it is not safe to use for these purposes in high concentrations as use of raspberry ketone and its derivative is linked to causing loss of skin pigmentation in people (leukoderma)High~0.25–0.45%est.

MethylpropanediolHelps dissolve other ingredients in a formulationMedium~5.6–6.9%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.3–5.2%est.

Pentaerythrityl tetraisostearateUsed to create a thicker product consistencyMedium~1.7–2%est.

Hydroxypropyl methylcelluloseUsed to create a thicker product consistency and stabilize the formulationMedium~0.5–0.75%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.4–0.6%est.

Cetearyl glucosideHelps water and oil in the product mix well together and improves product textureMedium~0.3–0.55%est.

Juniperus communis fruit extractBerry extract that might have some anti-oxidant effectMedium~0.25–0.5%est.

EthylhexylglycerinA preservativeMedium~0.3–0.55%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.3–0.6%est.

Disodium edtaStabilizes the product formulationMedium~0.3–0.55%est.

Sorbitan oleateHelps oil and water mix togetherMedium~0.3–0.6%est.

Sodium hyaluronate crosspolymerAttracts water into the upper layer of the skinMedium~0.3–0.55%est.

Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.25–0.5%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.3–0.5%est.

Benzyl glycolHelps dissolve other ingredients and preserve productsMedium~0.3–0.55%est.

1,2-hexanediolA preservativeMedium~0.3–0.5%est.

Comedogenic

5 ingredients rated 2 or more on the 0–5 pore-clogging scale

5 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.55–0.8%est.

Porphyridium cruentum extractA red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect3/5~0.3–0.55%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1.3–1.5%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.3–0.6%est.

Sorbitan oleateHelps oil and water mix together2/5~0.3–0.6%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Methylpropanediol~5.6–6.9%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol

Caprylic/capric triglyceride~4.3–5.2%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Glycerin~3–3.7%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Dimethicone~2.4–2.9%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Niacinamide~1.9–2.3%

Hero · Moisturizing

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Pentaerythrityl tetraisostearate~1.7–2%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency

More about Pentaerythrityl tetraisostearate

Cyclopentasiloxane~1.5–1.8%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane

Cetearyl alcohol~1.3–1.5%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Cetearyl olivate~0.95–1.15%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Cetearyl olivate

Cyclohexasiloxane~0.75–1.1%

Formula

Irritation risk: Low

Works for

Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane

Sorbitan olivate~0.6–0.9%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan olivate

Glyceryl stearate~0.6–0.85%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Butyrospermum parkii butter~0.55–0.8%

Under-dosedComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Hydroxypropyl methylcellulose~0.5–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Hydroxypropyl methylcellulose

Peg-100 stearate~0.55–0.85%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate

Pullulan~0.45–0.7%

Irritant · high

Irritation risk: High

Works for

Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan

Hydroxyacetophenone~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Helianthus annuus seed oil~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Sodium polyacrylate~0.4–0.6%

Formula

Irritation risk: Low

Works for

Mattifying

Used to create a gel-like product texture, as well as to stabilize emulsions

More about Sodium polyacrylate

Arginine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Carbomer~0.3–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Sodium acrylate/sodium acryloyldimethyl taurate copolymer~0.25–0.5%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer

Cetearyl glucoside~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil in the product mix well together and improves product texture

More about Cetearyl glucoside

Isohexadecane~0.45–0.7%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane

Juniperus communis fruit extract~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Berry extract that might have some anti-oxidant effect

More about Juniperus communis fruit extract

Eucalyptus globulus leaf extract~0.25–0.5%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Eucalyptus globulus leaf extract

Trehalose~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose

Ethylhexylglycerin~0.3–0.55%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Xanthan gum~0.3–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Polysorbate 80~0.35–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Polysorbate 80

Porphyridium cruentum extract~0.3–0.55%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

A red algae extract. Can help attract water to the upper layer of the skin and might have an antioxidant effect

More about Porphyridium cruentum extract

Parfum~0.3–0.55%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Glycine soja oil~0.3–0.6%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Adenosine~0.3–0.55%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Sodium hyaluronate~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Disodium edta~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Sorbitan oleate~0.3–0.6%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together

More about Sorbitan oleate

Malt extract~0.3–0.55%

Formula

Irritation risk: Low

More about Malt extract

Propanediol~0.3–0.6%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Sodium hyaluronate crosspolymer~0.3–0.55%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Attracts water into the upper layer of the skin

More about Sodium hyaluronate crosspolymer

Bixa orellana seed oil~0.3–0.6%

Formula

Irritation risk: Low

More about Bixa orellana seed oil

Hydrolyzed glycosaminoglycans~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

Long sugars that help attract water to the upper layer of the skin

More about Hydrolyzed glycosaminoglycans

Olea europaea leaf extract~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract

Glycyrrhiza glabra root extract~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Taraxacum officinale leaf extract~0.3–0.55%

Formula

Irritation risk: Low

More about Taraxacum officinale leaf extract

Magnolia officinalis bark extract~0.3–0.55%

Formula

Irritation risk: Low

More about Magnolia officinalis bark extract

Fructan~0.3–0.55%

Formula

Irritation risk: Low

More about Fructan

Hydrolyzed elastin~0.35–0.6%

Formula

Irritation risk: Low

More about Hydrolyzed elastin

Hydrolyzed collagen~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen

Hydrogenated polyisobutene~0.35–0.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene

Glyceryl polymethacrylate~0.35–0.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture

More about Glyceryl polymethacrylate

Benzyl glycol~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Helps dissolve other ingredients and preserve products

More about Benzyl glycol

Tocopherol~0.3–0.6%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Propylene glycol~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol

Rosa damascena flower extract~0.3–0.55%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Rosa damascena flower extract

Rhodiola rosea root extract~0.35–0.65%

Formula

Irritation risk: Low

More about Rhodiola rosea root extract

Hydrolyzed hyaluronic acid~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid

Ginkgo biloba leaf extract~0.3–0.55%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidationAnti-blemishAntibacterialAnti-inflammatory

A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating

More about Ginkgo biloba leaf extract

Zanthoxylum piperitum fruit extract~0.3–0.55%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Plant extract that has some anti-oxidant properties. It can be irritating. Can be used to improve the product's smell

More about Zanthoxylum piperitum fruit extract

Pulsatilla koreana extract~0.3–0.55%

Formula

Irritation risk: Low

More about Pulsatilla koreana extract

Butylene glycol~0.3–0.55%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

1,2-hexanediol~0.3–0.5%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Raspberry ketone~0.25–0.45%

Irritant · high

Irritation risk: High

Used as a fragrance. It can reduce skin pigmentation, but it is not safe to use for these purposes in high concentrations as use of raspberry ketone and its derivative is linked to causing loss of skin pigmentation in people (leukoderma)

More about Raspberry ketone

Palmitoyl tripeptide-5~0.25–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5

Hyaluronic acid~0.25–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid

Palmitoyl tetrapeptide-7~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7

Anemarrhena asphodeloides root extract~0.2–0.4%

Formula

Irritation risk: Low

Works for

Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Anemarrhena asphodeloides root extract

Acetyl hexapeptide-8~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8

Copper tripeptide-1~0.15–0.3%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.

More about Copper tripeptide-1

Palmitoyl oligopeptide~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

CleansingMoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl oligopeptide

Palmitoyl tripeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1

Oligopeptide-29~0.15–0.3%

Formula

Irritation risk: Low

More about Oligopeptide-29

Oligopeptide-32~0.1–0.2%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Oligopeptide-32

Palmitoyl pentapeptide-4~0.1–0.15%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl pentapeptide-4

Ingredient list view

Water, Methylpropanediol, Caprylic/capric triglyceride, Glycerin, Dimethicone, Niacinamide, Pentaerythrityl tetraisostearate, Cyclopentasiloxane, Cetearyl alcohol, Cetearyl olivate, Cyclohexasiloxane, Sorbitan olivate, Glyceryl stearate, Butyrospermum parkii butter, Hydroxypropyl methylcellulose, Peg-100 stearate, Pullulan, Hydroxyacetophenone, Helianthus annuus seed oil, Sodium polyacrylate, Arginine, Carbomer, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Cetearyl glucoside, Isohexadecane, Juniperus communis fruit extract, Eucalyptus globulus leaf extract, Trehalose, Ethylhexylglycerin, Xanthan gum, Polysorbate 80, Porphyridium cruentum extract, Parfum, Glycine soja oil, Adenosine, Sodium hyaluronate, Disodium edta, Sorbitan oleate, Malt extract, Propanediol, Sodium hyaluronate crosspolymer, Bixa orellana seed oil, Hydrolyzed glycosaminoglycans, Olea europaea leaf extract, Glycyrrhiza glabra root extract, Taraxacum officinale leaf extract, Magnolia officinalis bark extract, Fructan, Hydrolyzed elastin, Hydrolyzed collagen, Hydrogenated polyisobutene, Glyceryl polymethacrylate, Benzyl glycol, Tocopherol, Propylene glycol, Rosa damascena flower extract, Rhodiola rosea root extract, Hydrolyzed hyaluronic acid, Ginkgo biloba leaf extract, Zanthoxylum piperitum fruit extract, Pulsatilla koreana extract, Butylene glycol, 1,2-hexanediol, Raspberry ketone, Palmitoyl tripeptide-5, Hyaluronic acid, Palmitoyl tetrapeptide-7, Anemarrhena asphodeloides root extract, Acetyl hexapeptide-8, Copper tripeptide-1, Palmitoyl oligopeptide, Palmitoyl tripeptide-1, Oligopeptide-29, Oligopeptide-32, Palmitoyl pentapeptide-4

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	MEDI-PEELPeptide 9 Hyaluronic Volumy Eye CreamYOUR PRODUCT	NEOGEN X SUR.MEDICV.Biome Advanced Eye Cream	SWANICOCOPeptine Biome Eye Cream	EyenlipSalmon Oil Repair Eye Cream
Match	—	89%	86%	86%
Price	$23.36	$25.16+$1.80	$18.00−$5.36	$9.90−$13.46
Shared key ingredients	—	15 of 29	13 of 29	11 of 29
Key difference	—	Hexapeptide-11	Acetyl Dipeptide-1 Cetyl Ester	Palmitoyl Hexapeptide-12
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"MEDI-PEEL - Peptide 9 Hyaluronic Volumy Eye Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Acetyl hexapeptide-8, arginine, glycerin, hyaluronic acid and hydrolyzed collagen in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, glycine soja oil, hydrolyzed collagen and arginine) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

We particularly like that there is a good concentration of Niacinamide (1.90% - 2.30%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
We like that this moisturizer contains peptides (palmitoyl pentapeptide-4 0.10% - 0.15%, oligopeptide-32 0.10% - 0.20%, palmitoyl tripeptide-1 0.20% - 0.35%, palmitoyl oligopeptide 0.25% - 0.45%, copper tripeptide-1 0.15% - 0.30%, acetyl hexapeptide-8 0.20% - 0.35%, palmitoyl tetrapeptide-7 0.30% - 0.50% and palmitoyl tripeptide-5 0.25% - 0.50%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.30% - 0.55%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e and butyrospermum parkii butter

Irritation risk

There are quite a few common irritants in this product, including ingredients without particular skin benefits. We would not recommend it for sensitive skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 34.00A$ in Australia, for 21.00£ in the United Kingdom and for 32.70$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 30 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Dimethicone as a protective ingredient in topical medicationsjaad.org
3
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
4
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
5
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
6
Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmeticsncbi.nlm.nih.gov
7
Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
8
Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
9
Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
10
Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
11
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
12
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
13
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
14
Surfactants and experimental irritant contact dermatitisncbi.nlm.nih.gov
15
Wound Repair Potential of Olea europaea L. Leaf Extracts Revealed by In Vivo Experimental Models and Comparative Evaluation of the Extracts' Antioxidant Activityresearchgate.net
16
Final report of the cosmetic ingredient review expert panel on the safety assessment of Polyisobutene and Hydrogenated Polyisobutene as used in cosmeticssemanticscholar.org
17
Vitamin E in dermatologyncbi.nlm.nih.gov
18
Vitamin E and Skin Healthlpi.oregonstate.edu
19
Propylene Glycolpubmed.ncbi.nlm.nih.gov
20
Skin-sensitizing and irritant properties of propylene glycolonlinelibrary.wiley.com
21
Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
22
Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
23
Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmeticscir-safety.org
24
Cosmeceutical Critique: Ginkgo Bilobamdedge.com
25
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
26
Tyrosinase-Catalyzed Oxidation of the Leukoderma-Inducing Agent Raspberry Ketone Produces (E)-4-(3-Oxo-1-butenyl)-1,2-benzoquinone: Implications for Melanocyte Toxicitypubs.acs.org
27
Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Datancbi.nlm.nih.gov
28
Topical Peptide Treatments with Effective Anti-Aging Resultsmdpi.com
29
Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin - A pilot clinical, histologic, and ultrastructural studyinfona.pl
30
Selected Biomarkers Revealed Potential Skin Toxicity Caused by Certain Copper Compoundsnature.com

MEDI-PEELPeptide 9 Hyaluronic Volumy Eye Cream

Buy at Yesstyle$32.70 Amazon

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Buy at Yesstyle$32.70 Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.