Works for
Anti-agingNiacinamide, Adenosine + 10 moreWorks well
“It brightens, detoxifies and firms skin while also improving appearance of fine lines.”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, acetyl octapeptide-3, copper tripeptide-1, hexapeptide-9, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, tripeptide-1.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
MoisturizingNiacinamide, Urea + 21 moreWorks well
“Infused with 99% 24K gold alongside adenosine and niacinamide, this ampoule offers much needed hydration to your skin.”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
allantoin, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: palmitoyl tetrapeptide-7, palmitoyl tripeptide-1.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, acetyl octapeptide-3, copper tripeptide-1, hexapeptide-9, niacinamide, nonapeptide-1, palmitoyl pentapeptide-4, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, panthenol, tripeptide-1, urea
Anti-blemishSide benefit · Niacinamide, Allantoin + 3 moreWorks well
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
ExfoliationSide benefit · Hydroxyethyl urea, Urea + 1 moreWorks well
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: hydroxyethyl urea.
Evens skin toneSide benefit · Niacinamide, Camellia sinensis leaf extractWorks well
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: hydroxyethyl urea, niacinamide
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Can it cause trouble?
Irritancy6 strong irritants: Parfum, Ocimum sanctum leaf extract + 4 more — patch-test recommendedHigh risk
Comedogenic1 ingredient rated 2 or more on the 0–5 pore-clogging scale1 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Butylene glycol~6–7.3%
- Irritation risk
- Low
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
More about Butylene glycolNiacinamide~4.3–5.3%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamideMethyl gluceth-20~3–3.7%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and soften it
More about Methyl gluceth-20Hydroxyethyl urea~2.3–2.8%
- Irritation risk
- Low
A derivative of urea, a compound that is naturally present in skin. Attracts water to the upper layer of the skin. Can enhance penetration of other ingredients
More about Hydroxyethyl ureaPolysorbate 20~1.8–2.2%
Caprylyl glycol~1.5–1.9%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolCarbomer~1.3–1.6%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerAllantoin~0.8–1.15%
- Irritation risk
- Low
Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated
More about AllantoinAmmonium lactate~0.7–1.05%
- Irritation risk
- Low
Urea~0.55–0.8%
- Irritation risk
- Low
Naturally present in skin (urea makes up about 7% of natural moisturizing factors in skin). Attracts water to the upper layer of the skin. Also has a positive effect on the skin barrier beyond the humectant action. Can enhance penetration of other ingredients. Is an exfoliating ingredient when used in high concentrations
More about UreaPanthenol~0.5–0.7%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and can help improve skin barrier function
More about PanthenolAdenosine~0.4–0.6%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineDisodium edta~0.35–0.6%
Sodium hyaluronate~0.3–0.55%
- Irritation risk
- Low
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
More about Sodium hyaluronateRehmannia chinensis root extract~0.3–0.5%
- Irritation risk
- Low
Phenoxyethanol~0.3–0.55%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolTriethanolamine~0.3–0.5%
- Irritation risk
- Medium
Used to adjust pH of the product and can help improve the product's smell
More about TriethanolamineParfum~0.25–0.45%
- Irritation risk
- High
An aromatic blend of unspecified and possibly irritating ingredients
More about ParfumCurcuma longa root extract~0.2–0.4%
- Irritation risk
- High
A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant
More about Curcuma longa root extractPalmitoyl tetrapeptide-7~0.25–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tetrapeptide-7Nonapeptide-1~0.2–0.4%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Nonapeptide-1Melia azadirachta flower extract~0.2–0.35%
- Irritation risk
- Medium
A plant extract that might be helpful to neutralize free radicals in skin
More about Melia azadirachta flower extractCamellia sinensis leaf extract~0.25–0.45%
- Irritation risk
- Low
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
More about Camellia sinensis leaf extractOcimum sanctum leaf extract~0.2–0.4%
- Irritation risk
- High
A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals
More about Ocimum sanctum leaf extractGold~0.25–0.45%
Tripeptide-1~0.25–0.45%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Tripeptide-1Acetyl octapeptide-3~0.2–0.4%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl octapeptide-3Ethylhexylglycerin~0.25–0.45%
Palmitoyl pentapeptide-4~0.2–0.4%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl pentapeptide-4Ppg-26-buteth-26~0.25–0.45%
Acetyl hexapeptide-8~0.2–0.4%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl hexapeptide-8Ci 15985~0.25–0.45%
Rosmarinus officinalis leaf extract~0.2–0.4%
- Irritation risk
- High
Can be helpful in reducing inflammation in skin, including inflamed acne. It can be irritating
More about Rosmarinus officinalis leaf extractLavandula angustifolia extract~0.2–0.4%
- Irritation risk
- High
Used for fragrance and contains volatile compounds that can irritate the skin
More about Lavandula angustifolia extractCopper tripeptide-1~0.2–0.4%
- Irritation risk
- Low
A naturally occurring peptide. One of the most studied peptides in dermatology. It is sometimes abbreviated GHK-Cu. Belongs to the class of carrier peptides. It stimulates both synthesis and breakdown of collagen in skin. It is released in skin wounds and inflammation to support healing. It accelerates wound-healing of the skin and can stimulate hair growth. There are preliminary studies that confirm that copper tripeptide can help support collagen production reducing fine lines and wrinkles and decrease inflammation in skin.
More about Copper tripeptide-1Rosmarinus officinalis extract~0.2–0.4%
- Irritation risk
- High
Lavandula angustifolia extract~0.2–0.4%
- Irritation risk
- High
Used for fragrance and contains volatile compounds that can irritate the skin
More about Lavandula angustifolia extractGlycerin~0.25–0.5%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinPalmitoyl tripeptide-1~0.25–0.5%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-1Hexapeptide-9~0.25–0.45%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Hexapeptide-9Corallina officinalis extract~0.25–0.45%
- Irritation risk
- Low
- Comedogenicity
- 3/5
Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants
More about Corallina officinalis extractCamellia sinensis leaf extract~0.25–0.45%
- Irritation risk
- Low
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
More about Camellia sinensis leaf extractHexyl cinnamal~0.2–0.35%
Melia azadirachta leaf extract~0.2–0.4%
- Irritation risk
- High
A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating
More about Melia azadirachta leaf extractPortulaca oleracea extract~0.2–0.4%
- Irritation risk
- Medium
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
More about Portulaca oleracea extractGold~0.15–0.3%
Ci 19140~0.15–0.3%
Peg-40 hydrogenated castor oil~0.2–0.35%
- Irritation risk
- Medium
Helps oil and water mix together
More about Peg-40 hydrogenated castor oil1,2-hexanediol~0.15–0.3%
Fructan~0.1–0.2%
- Irritation risk
- Low
Portulaca oleracea extract~0.1–0.2%
- Irritation risk
- Medium
A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin
More about Portulaca oleracea extractIngredient list view
Water, Butylene glycol, Niacinamide, Methyl gluceth-20, Hydroxyethyl urea, Polysorbate 20, Caprylyl glycol, Carbomer, Allantoin, Ammonium lactate, Urea, Panthenol, Adenosine, Disodium edta, Sodium hyaluronate, Rehmannia chinensis root extract, Phenoxyethanol, Triethanolamine, Parfum, Curcuma longa root extract, Palmitoyl tetrapeptide-7, Nonapeptide-1, Melia azadirachta flower extract, Camellia sinensis leaf extract, Ocimum sanctum leaf extract, Gold, Tripeptide-1, Acetyl octapeptide-3, Ethylhexylglycerin, Palmitoyl pentapeptide-4, Ppg-26-buteth-26, Acetyl hexapeptide-8, Ci 15985, Rosmarinus officinalis leaf extract, Lavandula angustifolia extract, Copper tripeptide-1, Rosmarinus officinalis extract, Lavandula angustifolia extract, Glycerin, Palmitoyl tripeptide-1, Hexapeptide-9, Corallina officinalis extract, Camellia sinensis leaf extract, Hexyl cinnamal, Melia azadirachta leaf extract, Portulaca oleracea extract, Gold, Ci 19140, Peg-40 hydrogenated castor oil, 1,2-hexanediol, Fructan, Portulaca oleracea extract
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| MEDI-PEELLuxury 24K Gold AmpouleYOUR PRODUCT | EqqualberryNAD+ Peptide Boosting Serum | ArenciaDeep Water Surge Serum 30 | RETURNUThe Firm Ampoule | |
|---|---|---|---|---|
| Match | — | 91% | 90% | 90% |
| Price | — | $17.91 | $15.74 | $24.76 |
| Shared key ingredients | — | 15 of 21 | 13 of 21 | 13 of 21 |
| Key difference | — | Acetyl Tetrapeptide-3 | Oligopeptide-1 | Bakuchiol |
| Irritancy | High | Medium | Medium | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
More alternatives: Matkas Hyaluronic Acid Firming Boost SerumBELLAMONSTER Blemish Care Solution Ampoule
Product summary
"MEDI-PEEL - Luxury 24K Gold Ampoule" is effective for: Anti-blemish, Exfoliation, Evens skin tone, Moisturizing and Anti-aging
Ingredient callouts
- A good concentration of Niacinamide (4.30% - 5.30%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- Peptides (hexapeptide-9 0.20% - 0.40%, palmitoyl tripeptide-1 0.25% - 0.50%, copper tripeptide-1 0.20% - 0.40%, acetyl hexapeptide-8 0.20% - 0.40%, palmitoyl pentapeptide-4 0.20% - 0.40%, acetyl octapeptide-3 0.20% - 0.40%, tripeptide-1 0.25% - 0.40%, nonapeptide-1 0.20% - 0.35% and palmitoyl tetrapeptide-7 0.25% - 0.45%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Adenosine 0.40% - 0.60%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
- In addition, this product contains Allantoin (0.75% - 1.15%). Allantoin is helpful in wound-healing and can help restore the skin barrier faster. It might also be able to improve scars, but the evidence is not very strong for this.
- Humectants (hexapeptide-9 0.20% - 0.40%, glycerin 0.25% - 0.50%, panthenol 0.45% - 0.70%, acetyl hexapeptide-8 0.20% - 0.40%, acetyl octapeptide-3 0.20% - 0.40%, sodium hyaluronate 0.30% - 0.55%, urea 0.55% - 0.80% and hydroxyethyl urea 2.30% - 2.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Price
The product retails for 38.50A$ in Australia and for 63.56$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 26 studies and safety reviews.
- 1
- 2
- 3
- 4
- 5Topical urea in skincare: A reviewpubmed.ncbi.nlm.nih.gov
- 6Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
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