Mary&May Spicule Collagen PDRN Cream 15g

Mary&May Spicule Collagen PDRN Cream 15g

Efficacy100/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Anti-aging
4 ingredients credited for this claim
Strong support
What the product description says
“DESCRIPTION Mary & May Spicule Collagen PDRN Cream boosts elasticity for a youthful look.”
Source: Lila Beauty

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.5%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.4%
Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.5%
Moisturizing
Not advertised by the brand · 23 ingredients credited for this claim
Strong support

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, panthenol

Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.5–0.8%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.35–0.65%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~1.7–2.1%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.2–0.35%
CholesterolKey active· EmollientEffect: HighAn emollient that is naturally found in skin~0.3–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–4.8%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.1–0.2%
Hydrolyzed collagenKey active· Humectant, EmollientEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.65–0.95%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.4%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~2.3–2.9%
Polyglutamic acidKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin.~0.2–0.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.5%
Brassica campestris sterolsKey active· EmollientEffect: MediumHelp soften the upper layer of the skin~0.35–0.6%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~0.5–0.75%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.5%
Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~0.55–0.85%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.7–1.05%
Dextrin· HumectantEffect: LowA sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin~0.3–0.5%
Oleic acid· EmollientEffect: LowHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness~0.15–0.3%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.45%
Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.3–0.6%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.5%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.25–0.45%
Evens skin tone
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.4%
Anti-blemish
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.9–2.4%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.25–0.45%

Can it cause trouble?

Irritancy
1 strong irritant: Gardenia florida fruit extract
Medium risk
We flagged 17 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Gardenia florida fruit extractUsed as a fragrance. Can be irritating.High~0.25–0.5%est.
MethylpropanediolHelps dissolve other ingredients in a formulationMedium~5.8–7.1%est.
1,2-hexanediolA preservativeMedium~2.3–2.8%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~1.7–2.1%est.
Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~0.55–0.85%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~0.5–0.75%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.5–0.7%est.
C12-20 alkyl glucosideHelps water and oil mix togetherMedium~0.45–0.7%est.
Polyglyceryl-10 laurateHelps water and oil mix togetherMedium~0.3–0.55%est.
EthylhexylglycerinA preservativeMedium~0.25–0.5%est.
Lauryl glucosideHelps oil and water mix togetherMedium~0.4–0.6%est.
Polyglyceryl-6 laurateHelps oil and water mix togetherMedium~0.25–0.5%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Caprylyl/capryl glucosideHelps oil and water mix together. Can be used as a cleansing agentMedium~0.35–0.6%est.
Sorbitan oleateHelps oil and water mix togetherMedium~0.25–0.45%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.1–0.2%est.
Oleic acidHelps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin drynessMedium~0.15–0.3%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.3–0.6%est.
Sorbitan oleateHelps oil and water mix together2/5~0.25–0.45%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Methylpropanediol~5.8–7.1%
Irritant · medium
Irritation risk
Medium

Helps dissolve other ingredients in a formulation

More about Methylpropanediol
Glycerin~3.9–4.8%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
1,2-hexanediol~2.3–2.8%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Panthenol~2.3–2.9%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Niacinamide~1.9–2.4%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishEvens skin toneAnti-agingMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Caprylic/capric triglyceride~1.7–2.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Polypropylsilsesquioxane~1.5–1.9%
Formula
C14-22 alcohols~1.2–1.4%
Formula
Irritation risk
Low

A non-drying alcohol that helps stabilize product formulations

More about C14-22 alcohols
Ammonium acryloyldimethyltaurate/vp copolymer~0.95–1.15%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Glyceryl stearate~0.7–1.05%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Hydrolyzed collagen~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Hydrolyzed collagen
Cetyl ethylhexanoate~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate
Vinyl dimethicone~0.5–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone
Macadamia ternifolia seed oil~0.5–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Acrylates/c10-30 alkyl acrylate crosspolymer~0.5–0.7%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
C12-20 alkyl glucoside~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about C12-20 alkyl glucoside
Arginine~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Sodium acrylate/sodium acryloyldimethyl taurate copolymer~0.3–0.6%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer
Brassica campestris sterols~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Help soften the upper layer of the skin

More about Brassica campestris sterols
Polyglyceryl-10 laurate~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Polyglyceryl-10 laurate
Polyisobutene~0.3–0.6%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Dextrin~0.3–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

A sugar that is used to stabilize the product formulation. Can help attract water to the upper layer of the skin

More about Dextrin
Tocopherol~0.3–0.5%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryMoisturizingAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Allantoin~0.25–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces rednessAnti-blemishReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Ethylhexylglycerin~0.25–0.5%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Phytosteryl/behenyl/octyldodecyl lauroyl glutamate~0.25–0.5%
Formula
Cholesterol~0.3–0.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally found in skin

More about Cholesterol
Hydrolyzed sponge~0.25–0.5%
Formula
Gardenia florida fruit extract~0.25–0.5%
Irritant · high
Irritation risk
High

Used as a fragrance. Can be irritating.

More about Gardenia florida fruit extract
Xanthan gum~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Butyrospermum parkii butter~0.3–0.6%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Adenosine~0.25–0.5%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Lauryl glucoside~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Lauryl glucoside
Hydrogenated lecithin~0.3–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Sodium hyaluronate~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Polyglyceryl-6 laurate~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Polyglyceryl-6 laurate
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Caprylyl/capryl glucoside~0.35–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Caprylyl/capryl glucoside
Sorbitan oleate~0.25–0.45%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan oleate
Polyglutamic acid~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin.

More about Polyglutamic acid
Myristyl glucoside~0.25–0.5%
Formula
Ceramide np~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Glyceryl acrylate/acrylic acid copolymer~0.1–0.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Stearic acid~0.25–0.45%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Pvm/ma copolymer~0.15–0.25%
Formula
Oleic acid~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
CleansingAnti-inflammatoryMoisturizing

Helps soften the upper layer of the skin. At the same time, it can weaken the skin's barrier enhancing penetration of other ingredients and increasing the risk of skin dryness

More about Oleic acid
Sodium guaiazulene sulfonate~0.1–0.15%
Formula
Irritation risk
Low
Works for
Cleansing
More about Sodium guaiazulene sulfonate
Sodium dna~0.05–0.15%
Formula
Irritation risk
Low
More about Sodium dna
Ingredient list view

Water, Methylpropanediol, Glycerin, 1,2-hexanediol, Panthenol, Niacinamide, Caprylic/capric triglyceride, Polypropylsilsesquioxane, C14-22 alcohols, Ammonium acryloyldimethyltaurate/vp copolymer, Glyceryl stearate, Hydrolyzed collagen, Cetyl ethylhexanoate, Vinyl dimethicone, Macadamia ternifolia seed oil, Acrylates/c10-30 alkyl acrylate crosspolymer, C12-20 alkyl glucoside, Arginine, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Brassica campestris sterols, Polyglyceryl-10 laurate, Polyisobutene, Dextrin, Tocopherol, Allantoin, Ethylhexylglycerin, Phytosteryl/behenyl/octyldodecyl lauroyl glutamate, Cholesterol, Hydrolyzed sponge, Gardenia florida fruit extract, Xanthan gum, Butyrospermum parkii butter, Adenosine, Lauryl glucoside, Hydrogenated lecithin, Sodium hyaluronate, Polyglyceryl-6 laurate, Disodium edta, Caprylyl/capryl glucoside, Sorbitan oleate, Polyglutamic acid, Myristyl glucoside, Ceramide np, Glyceryl acrylate/acrylic acid copolymer, Stearic acid, Pvm/ma copolymer, Oleic acid, Sodium guaiazulene sulfonate, Sodium dna

Compare prices

Retailers ranked by price — lowest first.

Lila Beauty
≈ $9.73
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Amazon AustraliaPrice as of 9/24/2026 16:42 GMT
≈ $13.40
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Mary&MaySpicule Collagen PDRN Cream 15gYOUR PRODUCTACWELLLicorice pH Balancing Extreme Moisture Cream 55mlCOSNORIPanthenol Barrier CreamTOSOWOONGDexpanthenol Cream
Match—92%91%89%
Price$18.44$39.60+$21.16$16.74−$1.70$19.10+$0.66
Shared key ingredients—13 of 168 of 1611 of 16
Key difference—Ceramide NsMadecassosideMadecassoside
Irritancy Medium Medium Low Medium
Drying alcohol— Contains drying alcohol — Contains drying alcohol
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Product summary

"Mary&May - Buy Mary May Spicule Collagen PDRN Cream Australia - Korean Skincare Online" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Mary& May - Buy Mary May Spicule Collagen PDRN Cream Australia - Korean Skincare Online ticks this box. Humectants in this product (panthenol, arginine, glycerin, glyceryl acrylate/acrylic acid copolymer and hydrolyzed collagen) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Ceramide np, cholesterol, hydrolyzed collagen, vinyl dimethicone and arginine in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We particularly like that there is a good concentration of Niacinamide (1.90% - 2.40%) in this moisturizer. Niacinamide is a well-studied multi-tasking active. It is a great ingredient to have in a moisturizer. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and help improve the skin tone, reducing pigmentation marks.
  • As a plus, this moisturizer also contains Ceramides (ceramide np 0.20% - 0.35%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Adenosine 0.25% - 0.50%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Panthenol (pro-vitamin B5) at about 2.30% - 2.90% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: stearic acid, butyrospermum parkii butter, allantoin and vitamin e

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 13.95A$ in Australia.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 26 studies and safety reviews.

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Mary&May Spicule Collagen PDRN Cream 15g
Mary&MaySpicule Collagen PDRN Cream 15g

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.