La Roche-Posay Toleriane Ultra Night Cream for Face

La Roche-Posay Toleriane Ultra Night Cream for Face

Efficacy100/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Moisturizing
11 ingredients credited for this claim
Strong support
What the product description says
“Toleriane Ultra Night Cream for Face”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glyceryl acrylate/acrylic acid copolymer.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.1–3.2%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.1–6.1%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.4–2.2%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.8%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.2–0.8%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~1.7–2.5%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.45%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.4–5.1%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.7%
Acetyl dipeptide-1 cetyl esterUnder-dosedEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Anti-aging
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.8%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.1–3.2%
Acetyl dipeptide-1 cetyl esterUnder-dosedEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.05–0.2%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.05–0.1%
Evens skin tone
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.8%
Anti-blemish
Not advertised by the brand · 2 ingredients credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.8%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.7%

Can it cause trouble?

Irritancy
1 strong irritant: Salvia miltiorrhiza root extract
Medium risk
We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salvia miltiorrhiza root extractAn aromatic plant root extract with a mint-like smell. Can be irritating. Used as a fragrance. Might have some anti-oxidant effectHigh~0.4–0.9%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~1.7–2.5%est.
Pyridoxine hclMight help neutralize free radicals in skinMedium~0.95–1.4%est.
Zea mays starchUsed to thicken the product's consistencyMedium~0.5–1.1%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.2–0.8%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.15–0.5%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.45%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.3%est.
Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationMedium~0.05–0.25%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.1–3.2%est.
Zea mays starchUsed to thicken the product's consistency3/5~0.5–1.1%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.1–6.1%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~3.4–5.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Propanediol~2.7–4%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Butyrospermum parkii butter~2.1–3.2%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Pentylene glycol~1.7–2.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Squalane~1.4–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Niacinamide~1.2–1.8%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-blemishAnti-agingEvens skin toneMoisturizingReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Ammonium polyacryloyldimethyl
Not recognized
Pyridoxine hcl~0.95–1.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl
Polysorbate 20~0.8–1.2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Zea mays starch~0.5–1.1%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Mattifying

Used to thicken the product's consistency

More about Zea mays starch
Salvia miltiorrhiza root extract~0.4–0.9%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

An aromatic plant root extract with a mint-like smell. Can be irritating. Used as a fragrance. Might have some anti-oxidant effect

More about Salvia miltiorrhiza root extract
Allantoin~0.15–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishReduces irritationReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Glyceryl acrylate/acrylic acid copolymer~0.2–0.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Sodium hydroxide~0.15–0.65%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sphingomonas ferment extract~0.15–0.55%
Formula
Hydroxyacetophenone~0.15–0.5%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Caprylyl glycol~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Citric acid~0.05–0.3%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Trisodium ethylenediamine disuccinate~0.05–0.25%
Irritant · medium
Irritation risk
Medium

Used to improve stability of the formulation

More about Trisodium ethylenediamine disuccinate
Acetyl dipeptide-1 cetyl ester~0.05–0.2%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Xanthan gum~0.05–0.15%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Tocopherol~0.05–0.1%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ingredient list view

Water, Glycerin, Butylene glycol, Propanediol, Butyrospermum parkii butter, Pentylene glycol, Squalane, Niacinamide, Unknown, Pyridoxine hcl, Polysorbate 20, Zea mays starch, Salvia miltiorrhiza root extract, Allantoin, Glyceryl acrylate/acrylic acid copolymer, Sodium hydroxide, Sphingomonas ferment extract, Hydroxyacetophenone, Caprylyl glycol, Citric acid, Trisodium ethylenediamine disuccinate, Acetyl dipeptide-1 cetyl ester, Xanthan gum, Tocopherol

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Amazon USPrice as of 10/9/2026 21:52 GMT
$23.98
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$31.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
La Roche-PosayToleriane Ultra Night Cream for FaceYOUR PRODUCTUltraceuticalsUltra Calming Moisturiser CreamMarks and SpenceFormula Sleep & Replenish Light Sleep CreamThe SaemSnail Essential EX Wrinkle Solution Multi Cream
Match—98%88%87%
Price$23.98$109.00+$85.02—$23.00−$0.98
Shared key ingredients—5 of 74 of 74 of 7
Key difference—Ceramide NpUreaCopper Tripeptide-1
Irritancy Medium Low Medium Medium
Drying alcohol————
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Product summary

"La Roche-Posay - Toleriane Ultra Night Cream for Face" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Glycerin, glyceryl acrylate/acrylic acid copolymer, butylene glycol and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Butyrospermum parkii butter, squalane, caprylyl glycol and pentylene glycol in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • This moisturizer also contains Peptides (acetyl dipeptide-1 cetyl ester 0.05% - 0.20%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e and allantoin

Irritation risk

There are actives in this product that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 31.99$ in the United States.

For a detailed price comparison: click here.

La Roche-Posay Toleriane Ultra Night Cream for Face
La Roche-PosayToleriane Ultra Night Cream for Face

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.