La Roche-Posay - Toleriane Dermallergo Night

La Roche-Posay Toleriane Dermallergo Night

Efficacy100/100

Works for:

based on ingredients and %
  • Moisturizing
  • Anti-blemish
  • Anti-aging
  • Evens skin tone

Can it cause trouble?

  • Irritation risk: medium
  • Comedogenic risk ingredients: 2

Key actives

Niacinamide1.2% - 1.8%Allantoin0.2% - 0.75%Acetyl dipeptide-1 cetyl ester0.05% - 0.25%
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Price as of May 2, 2026.
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Product Summary

"La Roche-Posay - Toleriane Dermallergo Night" is a well-rounded moisturizing product. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. La Roche-Posay - Toleriane Dermallergo Night ticks this box. Glycerin, glyceryl acrylate/acrylic acid copolymer and butylene glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (butyrospermum parkii butter, squalane and pentylene glycol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl dipeptide-1 cetyl ester 0.05% - 0.25%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e and allantoin

Irritation risk

This moisturizer contains actives that can be irritating. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 37.50CA$ in Canada, for 49.99A$ in Australia, for 30.99$ in the United States and for 19.90£ in the United Kingdom.

For a detailed price comparison: click here.

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