La Roche-Posay - Substiane Eyes

La Roche-Posay Substiane Eyes

Efficacy75/100

Works for:

based on ingredients and %
  • Anti-aging
  • Anti-oxidation
  • Moisturizing

Can it cause trouble?

  • Irritation risk: low
  • Comedogenic risk ingredients: 2

Key actives

Acetyl dipeptide-1 cetyl ester0.15% - 0.25%Butyrospermum parkii butter4.2% - 5.1%Arginine pca0.2% - 0.4%
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Price as of May 18, 2026.
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Product Summary

Judging from the ingredient list, "La Roche-Posay - Substiane Eyes" works well for improving skin hydration To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. La Roche-Posay - Substiane Eyes ticks this box. Humectants in this product (arginine pca, glycerin, bis-peg-18 methyl ether dimethyl silane and propylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Prunus armeniaca kernel oil, beeswax, butyrospermum parkii butter, cera alba and dimethicone in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (acetyl dipeptide-1 cetyl ester 0.15% - 0.25%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: stearic acid

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 46.99$ in the United States and from 22.99£ up to 27.40£ in the United Kingdom.

For a detailed price comparison: click here.

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