La Roche-Posay Substiane Eye Cream for Depuffing and Replenishing Care

La Roche-Posay Substiane Eye Cream for Depuffing and Replenishing Care

Efficacy87/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
19 ingredients credited for this claim
Strong support
What the product description says
“Substiane Eye Cream for Depuffing and Replenishing Care”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine pca, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl dipeptide-1 cetyl ester

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.55–0.8%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.3–0.55%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–5.2%
Acetyl dipeptide-1 cetyl esterHeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
Prunus armeniaca kernel oilKey active· EmollientEffect: HighAn emollient that helps soften the skin~2.4–2.9%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%
Arginine pcaKey active· HumectantEffect: HighAn amino-acid. Helps attract water to the upper layer of the skin and can help neutralize free radicals in skin~0.25–0.45%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.65–0.95%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.2–5.1%
Cera albaKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.95–1.15%
Hydrolyzed linseed extractKey activeEffect: HighHelps soften the upper layer of the skin~0.2–0.4%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~0.95–1.15%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~1.7–2.1%
Cyclohexasiloxane· EmollientEffect: LowA silicone that serves as an emollient. Helps create a nice non-greasy feels~3.1–3.8%
Bis-peg-18 methyl ether dimethyl silane· Humectant, EmollientEffect: LowA type of silicone that helps soften the upper layer of the skin and create a nice product texture~0.3–0.55%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.5–0.7%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~0.5–0.75%
Pentaerythrityl tetraethylhexanoate· EmollientEffect: LowUsed to create a nice product consistency while softening the upper layer of the skin~2–2.4%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.65–0.95%
Anti-aging
4 ingredients credited for this claim
Moderate support
What the product description says
“Use as a daily eye moisturizer for loss of firmness, elasticity, and under-eye bags.”
Source: Walgreens

This product contains acetyl dipeptide-1 cetyl ester, serine. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl dipeptide-1 cetyl esterKey activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.4%
Arginine pcaEffect: LowAn amino-acid. Helps attract water to the upper layer of the skin and can help neutralize free radicals in skin~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.2–5.1%
Anti-oxidation
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product contains antioxidants (arginine pca) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Arginine pcaKey activeEffect: HighAn amino-acid. Helps attract water to the upper layer of the skin and can help neutralize free radicals in skin~0.25–0.45%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~4.2–5.1%
Prunus armeniaca kernel oilEffect: LowAn emollient that helps soften the skin~2.4–2.9%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~0.95–1.15%est.
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.35–0.6%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05%est.
Prunus armeniaca kernel oilAn emollient that helps soften the skinMedium~2.4–2.9%est.
Zea mays starchUsed to thicken the product's consistencyMedium~1.4–1.8%est.
Cera albaForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergenMedium~0.95–1.15%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.
Benzoic acidA preservativeMedium~0.1–0.2%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~4.2–5.1%est.
Zea mays starchUsed to thicken the product's consistency3/5~1.4–1.8%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–5.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butyrospermum parkii butter~4.2–5.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Cyclohexasiloxane~3.1–3.8%
Formula
Irritation risk
Low
Works for
Moisturizing

A silicone that serves as an emollient. Helps create a nice non-greasy feels

More about Cyclohexasiloxane
Prunus armeniaca kernel oil~2.4–2.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the skin

More about Prunus armeniaca kernel oil
Pentaerythrityl tetraethylhexanoate~2–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product consistency while softening the upper layer of the skin

More about Pentaerythrityl tetraethylhexanoate
Isohexadecane~1.7–2.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Zea mays starch~1.4–1.8%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Mattifying

Used to thicken the product's consistency

More about Zea mays starch
Silica~1.5–1.8%
Formula
Irritation risk
Low

Used to absorb oil and can temporarily mattify skin

More about Silica
Hydroxypropyl tetrahydropyrantriol~0.95–1.15%
Key activeIrritant · high
Irritation risk
High
Works for
Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol
Cera alba~0.95–1.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Cera alba
Beeswax~0.65–0.95%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Stearic acid~0.65–0.95%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Dimethicone~0.55–0.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Palmitic acid~0.5–0.75%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Peg-100 stearate~0.55–0.8%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Glyceryl stearate~0.5–0.7%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Propylene glycol~0.35–0.6%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Peg-20 stearate~0.35–0.6%
Formula
Irritation risk
Low
Works for
Cleansing
More about Peg-20 stearate
Bis-peg-18 methyl ether dimethyl silane~0.3–0.55%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

A type of silicone that helps soften the upper layer of the skin and create a nice product texture

More about Bis-peg-18 methyl ether dimethyl silane
Stearyl alcohol~0.3–0.6%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Dimethiconol~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Arginine pca~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An amino-acid. Helps attract water to the upper layer of the skin and can help neutralize free radicals in skin

More about Arginine pca
Serine~0.2–0.4%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Disodium edta~0.2–0.4%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Hydrolyzed linseed extract~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Hydrolyzed linseed extract
Acetyl dipeptide-1 cetyl ester~0.2–0.35%
Hero · Moisturizing
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl dipeptide-1 cetyl ester
Polysorbate 80~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.15–0.25%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.15–0.3%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Sodium benzoate~0.1–0.2%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Phenoxyethanol~0.1–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Benzoic acid~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Benzoic acid
Parfum~0.05%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Glycerin, Butyrospermum parkii butter, Cyclohexasiloxane, Prunus armeniaca kernel oil, Pentaerythrityl tetraethylhexanoate, Isohexadecane, Zea mays starch, Silica, Hydroxypropyl tetrahydropyrantriol, Cera alba, Beeswax, Stearic acid, Dimethicone, Palmitic acid, Peg-100 stearate, Glyceryl stearate, Propylene glycol, Peg-20 stearate, Bis-peg-18 methyl ether dimethyl silane, Stearyl alcohol, Dimethiconol, Arginine pca, Serine, Disodium edta, Hydrolyzed linseed extract, Acetyl dipeptide-1 cetyl ester, Polysorbate 80, Acrylamide/sodium acryloyldimethyltaurate copolymer, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Sodium benzoate, Phenoxyethanol, Benzoic acid, Parfum

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$46.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
La Roche-PosaySubstiane Eye Cream for Depuffing and Replenishing CareYOUR PRODUCTbareMineralsAgeless Genius Firming and Wrinkle Smoothing Eye CreamNo7Restore & Renew Multi Action Eye CreamAlgenistELEVATE Firming and Lifting Contouring Eye Cream
Match—55%55%54%
Price$46.99$39.13−$7.86$17.99−$29.00$36.00−$10.99
Shared key ingredients—4 of 123 of 124 of 12
Key difference—Arginine/Lysine PolypeptideAscorbyl GlucosideArginine/Lysine Polypeptide
Irritancy Medium Medium Medium Medium
Drying alcohol—— Contains drying alcohol —
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Product summary

"La Roche-Posay - Substiane Eye Cream for Depuffing and Replenishing Care" has a good moisturizing formula. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (arginine pca, glycerin and bis-peg-18 methyl ether dimethyl silane) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (prunus armeniaca kernel oil, beeswax, butyrospermum parkii butter, cera alba and dimethicone) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moistruizer also contains peptides (acetyl dipeptide-1 cetyl ester 0.20% - 0.35%). Peptides is a very big group of ingredients. They all consist of a different combination of amino-acids. Our skin produces peptides naturally. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of peptides is, but it is very likely that peptides in skincare are helpful. They might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails for 46.99$ in the United States.

For a detailed price comparison: click here.

La Roche-Posay Substiane Eye Cream for Depuffing and Replenishing Care
La Roche-PosaySubstiane Eye Cream for Depuffing and Replenishing Care

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