ISNTREE

ISNTREE Тонізуючий крем C-Niacin

Name: ISNTREE - Тонізуючий крем C-Niacin
Brand: ISNTREE

Efficacy100/100IrritancyMedium

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Works for

2 of 2 advertised claims delivered

Moisturizing

27 ingredients credited for this claim

Strong support

What the product description says

“Formulated with Deep Brightening Complex (Lycium Barbarum Fruit Extract, Euterpe Oleracea Fruit Extract, Camu Camu Extract and Hippophae Rhamnoides Oil) to nourish skin for a radiant complexion.”

Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, niacinamide, panthenol, phytosphingosine

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.9–1.35%

Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.1–0.3%

Hippophae rhamnoides oilKey active· EmollientEffect: HighA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.~0.15–0.7%

Beta-glucanKey activeEffect: HighHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.15–0.5%

Mangifera indica seed butterKey activeEffect: HighHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.1–0.35%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.1–0.35%

Carthamus tinctorius seed oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and might help calm down inflammation~0.15–0.6%

PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.15–0.6%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.15–0.5%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.05–0.2%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.1–0.4%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~2.4–3.7%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.15–0.6%

Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~0.15–0.5%

Glyceryl linolenateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.15–0.6%

Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~1–1.5%

Lycium barbarum fruit extractKey activeEffect: MediumA plant extract that can help neutralize free radicals in skin and attract water to its upper layer~0.3–0.75%

Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.15–0.65%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.1–0.35%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4.6–6.9%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.65%

Moringa oleifera seed oil· EmollientEffect: LowA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid~0.45–1.05%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~4.4–6.7%

Polyglyceryl-10 stearateEffect: LowHelps water and oil mix together and softens the upper layer of the skin~0.1–0.4%

Argania spinosa kernel oilUnder-dosedEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.15–0.5%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%

Evens skin tone

2 ingredients credited for this claim

Strong support

What the product description says

“Infused with 69% of Hippophae Rhamnoides Fruit Extract and niacinamide to brighten skin tone.”

Source: Yesstyle

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.3–1.9%

Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.05–0.15%

Anti-blemish

Not advertised by the brand · 5 ingredients credited for this claim

Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

PhytosphingosineEffect: LowA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.15–0.6%

Beta-glucanEffect: LowHelps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles~0.15–0.5%

Sodium ascorbyl phosphateUnder-dosedEffect: HighA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.1–0.4%

Anti-aging

Not advertised by the brand · 7 ingredients credited for this claim

Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: folic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.1–0.4%

Lycium barbarum fruit extractEffect: LowA plant extract that can help neutralize free radicals in skin and attract water to its upper layer~0.3–0.75%

Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.1–0.4%

Anti-oxidation

Not advertised by the brand · 13 ingredients credited for this claim

Moderate support

This product contains antioxidants (lycium barbarum fruit extract, pyridoxine) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Lycium barbarum fruit extractKey activeEffect: MediumA plant extract that can help neutralize free radicals in skin and attract water to its upper layer~0.3–0.75%

PyridoxineKey activeEffect: MediumMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating~0.1–0.35%

Carthamus tinctorius seed oilEffect: LowAn emollient that helps soften the skin and might help calm down inflammation~0.15–0.6%

Hippophae rhamnoides fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking~22–33%

Euterpe oleracea fruit extractEffect: LowA plant extract that can have some anti-oxidant effect in skin~0.2–0.75%

Myrciaria dubia fruit extractEffect: LowA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking~0.15–0.6%

Mangifera indica seed butterEffect: LowHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.1–0.35%

Hippophae rhamnoides oilEffect: LowA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.~0.15–0.7%

TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.1–0.35%

Sodium ascorbyl phosphateUnder-dosedEffect: MediumA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.1–0.4%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.1–0.5%

Argania spinosa kernel oilEffect: Low, below effective doseAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.15–0.5%

Can it cause trouble?

Irritancy

1 strong irritant: Retinyl palmitate

Medium risk

We flagged 24 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Hippophae rhamnoides oilA good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.High~0.15–0.7%est.

PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.1–0.35%est.

Ethyl hexanediolUsed to dissolve other ingredients. Might be irritatingHigh~0.1–0.4%est.

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.05–0.15%est.

Hippophae rhamnoides fruit extractA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lackingMedium~22–33%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~4.4–6.7%est.

1,2-hexanediolA preservativeMedium~0.35–0.85%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.9–1.35%est.

Moringa oleifera seed oilA plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acidMedium~0.45–1.05%est.

Lycium barbarum fruit extractA plant extract that can help neutralize free radicals in skin and attract water to its upper layerMedium~0.3–0.75%est.

Euterpe oleracea fruit extractA plant extract that can have some anti-oxidant effect in skinMedium~0.2–0.75%est.

Myrciaria dubia fruit extractA plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lackingMedium~0.15–0.6%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.65%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.15–0.6%est.

Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.1–0.4%est.

Thiamine hclCan help attract water to the upper layer of the skin. Is studied as a mosquito repellentMedium~0.1–0.35%est.

Glyceryl arachidonateHelps water and oil mix togetherMedium~0.15–0.55%est.

Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.15–0.5%est.

Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~0.15–0.5%est.

Polyglyceryl-10 stearateHelps water and oil mix together and softens the upper layer of the skinMedium~0.1–0.4%est.

Hydroxypropyl guarUsed to create a thicker product consistency and stabilize emulsionsMedium~0.1–0.45%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.1–0.5%est.

Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.1–0.3%est.

Disodium edtaStabilizes the product formulationMedium~0.05–0.1%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~1–1.5%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Hippophae rhamnoides fruit extract~22–33%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking

More about Hippophae rhamnoides fruit extract

Butylene glycol~4.6–6.9%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Pentylene glycol~4.4–6.7%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Water~3.4–5.1%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~2.4–3.7%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

1,2-hexanediol~0.35–0.85%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Niacinamide~1.3–1.9%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Ethylhexyl palmitate~1–1.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate

Caprylic/capric triglyceride~0.9–1.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Moringa oleifera seed oil~0.45–1.05%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

A plant oil that helps soften the upper layer of the skin. Is unlikely to be helpful in restoring skin barrier function due to the low content of linoleic acid

More about Moringa oleifera seed oil

Lycium barbarum fruit extract~0.3–0.75%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

A plant extract that can help neutralize free radicals in skin and attract water to its upper layer

More about Lycium barbarum fruit extract

Euterpe oleracea fruit extract~0.2–0.75%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that can have some anti-oxidant effect in skin

More about Euterpe oleracea fruit extract

Myrciaria dubia fruit extract~0.15–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might help neutralize free radicals in skin, but research on its effectiveness is lacking

More about Myrciaria dubia fruit extract

Hippophae rhamnoides oil~0.15–0.7%

Key activeIrritant · high

Irritation risk: High

Works for

MoisturizingAnti-oxidation

A good emollient. Contains various ingredients including vitamins and fatty acids that could work in the skin to neutralize free radicals and minimize moisture loss - if enough of these compounds is able to penetrate the skin in an active form.

More about Hippophae rhamnoides oil

Caprylyl glycol~0.15–0.65%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Beta-glucan~0.15–0.5%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritationAnti-oxidationAnti-agingAnti-blemish

Helps attract water to the upper layer of the skin, calm down inflammation and irritation, restore the barrier function and support wound healing. It can be helpful in reducing fine lines and wrinkles

More about Beta-glucan

Olea europaea fruit oil~0.15–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Carthamus tinctorius seed oil~0.15–0.6%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the skin and might help calm down inflammation

More about Carthamus tinctorius seed oil

Phytosphingosine~0.15–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-blemishAnti-inflammatory

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine

Folic acid~0.1–0.4%

Key active

Irritation risk: Low

Works for

Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid

Cyanocobalamin~0.1–0.4%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizing

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Sodium ascorbyl phosphate~0.1–0.4%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate

Biotin~0.1–0.35%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Thiamine hcl~0.1–0.35%

Irritant · medium

Irritation risk: Medium

Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent

More about Thiamine hcl

Pyridoxine~0.1–0.35%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine

Glyceryl arachidonate~0.15–0.55%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Glyceryl arachidonate

Mangifera indica seed butter~0.1–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Helps to soften the upper layer of the skin and might have some anti-oxidant effect

More about Mangifera indica seed butter

Sodium acrylate/sodium acryloyldimethyl taurate copolymer~0.15–0.6%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Sodium acrylate/sodium acryloyldimethyl taurate copolymer

Isohexadecane~0.15–0.65%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane

Ceramide np~0.15–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Argania spinosa kernel oil~0.15–0.5%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil

Hydrogenated lecithin~0.1–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin

Macadamia ternifolia seed oil~0.15–0.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil

Polyglyceryl-10 stearate~0.1–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps water and oil mix together and softens the upper layer of the skin

More about Polyglyceryl-10 stearate

Tocopherol~0.1–0.35%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Hydroxypropyl guar~0.1–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Used to create a thicker product consistency and stabilize emulsions

More about Hydroxypropyl guar

Panthenol~0.1–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Tocopheryl acetate~0.1–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Glyceryl linolenate~0.15–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Glyceryl linolenate

Carbomer~0.1–0.45%

Formula

Irritation risk: Low

Works for

Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer

Polysorbate 80~0.1–0.5%

Formula

Irritation risk: Low

Works for

Cleansing

Helps water and oil mix together

More about Polysorbate 80

Ethyl hexanediol~0.1–0.4%

Irritant · high

Irritation risk: High

Used to dissolve other ingredients. Might be irritating

More about Ethyl hexanediol

Glyceryl acrylate/acrylic acid copolymer~0.1–0.3%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer

Arginine~0.05–0.2%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Sucrose distearate~0.15–0.55%

Formula

Irritation risk: Low

Works for

Cleansing

More about Sucrose distearate

Pvm/ma copolymer~0.05–0.3%

Formula

Irritation risk: Low

More about Pvm/ma copolymer

Retinyl palmitate~0.05–0.15%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Disodium edta~0.05–0.1%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Ingredient list view

Hippophae rhamnoides fruit extract, Butylene glycol, Pentylene glycol, Water, Glycerin, 1,2-hexanediol, Niacinamide, Ethylhexyl palmitate, Caprylic/capric triglyceride, Moringa oleifera seed oil, Lycium barbarum fruit extract, Euterpe oleracea fruit extract, Myrciaria dubia fruit extract, Hippophae rhamnoides oil, Caprylyl glycol, Beta-glucan, Olea europaea fruit oil, Carthamus tinctorius seed oil, Phytosphingosine, Folic acid, Cyanocobalamin, Sodium ascorbyl phosphate, Biotin, Thiamine hcl, Pyridoxine, Glyceryl arachidonate, Mangifera indica seed butter, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Isohexadecane, Ceramide np, Argania spinosa kernel oil, Hydrogenated lecithin, Macadamia ternifolia seed oil, Polyglyceryl-10 stearate, Tocopherol, Hydroxypropyl guar, Panthenol, Tocopheryl acetate, Glyceryl linolenate, Carbomer, Polysorbate 80, Ethyl hexanediol, Glyceryl acrylate/acrylic acid copolymer, Arginine, Sucrose distearate, Pvm/ma copolymer, Retinyl palmitate, Disodium edta

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ISNTREEТонізуючий крем C-NiacinYOUR PRODUCT	iUNIKBeta Glucan 3X Barrier Cream 50ml	flounCarrot Blending Intense Cream	Mary&MayIdebenone + Blackberry Complex Intensive Cream
Match	—	88%	86%	85%
Price	$11.22	$23.78+$12.56	$14.54+$3.32	$25.97+$14.75
Shared key ingredients	—	7 of 17	5 of 17	8 of 17
Key difference	—	Adenosine	Ceramide Ns	Adenosine
Irritancy	Medium	Low	Low	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"ISNTREE - Тонізуючий крем C-Niacin" is effective for: Anti-blemish, Evens skin tone, Anti-aging and Moisturizing

Ingredient callouts

this product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.05% - 0.15%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
Ceramides (ceramide np 0.15% - 0.50% and phytosphingosine 0.15% - 0.60%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
Humectants (glyceryl acrylate/acrylic acid copolymer 0.10% - 0.30% and glycerin 2.40% - 3.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

About the brand

According to Cruelty-Free Kitty "ISNTREE" is cruelty free and so is its parent company.

Price

The product retails for 12.07$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 46 studies and safety reviews.

1
Abundance of active ingredients in sea-buckthorn oilncbi.nlm.nih.gov
2
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
3
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
4
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
5
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
6
Moringa oleifera seed oil: Composition, nutritional aspects and health attributesresearchgate.net
7
Moringa oleifera Seeds and Oil: Characteristics and Uses for Human Healthncbi.nlm.nih.gov
8
Water-soluble polysaccharide from dried Lycium barbarum fruits: Isolation, structural features and antioxidant activitysciencedirect.com
9
Lycium barbarum polysaccharide protects human keratinocytes against UVB-induced photo-damagetandfonline.com
10
Lycium Barbarum and Human Healthlink.springer.com
11
Total Oxidant Scavenging Capacity of Euterpe oleracea Mart. (Açaí) Seeds and Identification of Their Polyphenolic Compoundspubs.acs.org
12
Euterpe oleracea, Matricaria chamomilla, and Camellia sinensis as promising ingredients for development of skin care formulationssciencedirect.com
13
Antioxidant and Associated Capacities of Camu Camu (Myrciaria dubia): A Systematic Reviewncbi.nlm.nih.gov
14
β-Glucans: Multi-Functional Modulator of Wound Healingncbi.nlm.nih.gov
15
Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive Cosmetic Treatment of Skin Wrinkles with Beta-Glucanonlinelibrary.wiley.com
16
Skin Health Promotion Effects of Natural Beta-Glucan Derived from Cereals and Microorganisms: A Reviewonlinelibrary.wiley.com
17
Anticancer properties of low molecular weight oat beta-glucan – An in vitro studysciencedirect.com
18
A critical review on production and industrial applications 2 of beta-glucanssciencedirect.com
19
Improving skin function with CM-glucan, a biological response modifier from yeastonlinelibrary.wiley.com
20
Preparation, characterization, and biological properties of β-glucansncbi.nlm.nih.gov
21
Characterization of a new beta(1-3)-glucan branching activity of Aspergillus fumigatusncbi.nlm.nih.gov
22
Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oilonlinelibrary.wiley.com
23
Folic acid and creatine improve the firmness of human skin in vivopubmed.ncbi.nlm.nih.gov
24
Topical vitamin B12--a new therapeutic approach in atopic dermatitis-evaluation of efficacy and tolerability in a randomized placebo-controlled multicentre clinical trialpubmed.ncbi.nlm.nih.gov
25
Superiority of a vitamin B12-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasisncbi.nlm.nih.gov
26
Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgarisncbi.nlm.nih.gov
27
Sodium ascorbyl phosphate in topical microemulsionssciencedirect.com
28
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmeticseuropepmc.org
29
Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphatekarger.com
30
Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatmentonlinelibrary.wiley.com
31
Application of l-ascorbic acid and its derivatives (sodium ascorbyl phosphate and magnesium ascorbyl phosphate) in topical cosmetic formulations: stability studiesinis.iaea.org
32
Sodium L-ascorbyl-2-phosphate 5% lotion for the treatment of acne vulgaris: a randomized, double-blind, controlled trialonlinelibrary.wiley.com
33
Cutaneous Metabolism of Vitamin B-6sciencedirect.com
34
Extraction and Characteristics of Seed Kernel Oil from Mangopdfs.semanticscholar.org
35
Promising features of mango (Mangifera indica L.) kernel oil: a reviewncbi.nlm.nih.gov
36
Evaluation of the fatty acid composition of the seeds of Mangifera indica L. and their applicationncbi.nlm.nih.gov
37
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
38
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
39
Natural vegetable fats in the prevention of irritant contact dermatitisncbi.nlm.nih.gov
40
Fatty acids profile of oil from nine varieties of Macadamia nuttandfonline.com
41
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmeticscir-safety.org
42
Vitamin E in dermatologyncbi.nlm.nih.gov
43
Vitamin E and Skin Healthlpi.oregonstate.edu
44
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
45
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
46
Final Report on the Safety Assessment of Ethyl Hexanedioljournals.sagepub.com

ISNTREEТонізуючий крем C-Niacin

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