ISANA

ISANA Vital Night Cream

Name: ISANA - Vital Night Cream
Brand: ISANA

Efficacy75/100IrritancyHigh

See all ingredients

Works for

Moisturizing

Panthenol, Coco-caprylate + 14 more

Works well

What the product description says

“The nourishing formula helps support the skin’s moisture and lipid balance while promoting a smoother, firmer-looking complexion.”

Source: German Drugstore

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, pantolactone.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, helianthus annuus seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.35–0.8%

Coco-caprylateKey active· EmollientEffect: MediumAn emollient that softens skin and creates a nice product texture~2.9–4.3%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2.1–3.2%

Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~1.5–2.3%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.4–2%

Argania spinosa kernel oilKey active· EmollientEffect: HighAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties~0.9–1.35%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.55–1.35%

Glycine soja oilKey active· EmollientEffect: HighA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.~0.45–1.05%

Vitis vinifera seed oilKey active· EmollientEffect: HighA great emollient that can also have anti-oxidant properties~0.4–0.9%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.35–0.8%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.75%

PantolactoneKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.1–0.3%

Cocoglycerides· EmollientEffect: LowHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin~4.4–6.7%

Hydrogenated palm glycerides· EmollientEffect: LowAn emollient that softens the skin~1.8–2.7%

Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~1–1.6%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.7%

Anti-aging

Prunus amygdalus dulcis oil, Butyrospermum parkii butter + 1 more

Not delivered

What the product description says

“Nourishing Overnight Anti-Aging Care”

Source: German Drugstore

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.This ingredient - butyrospermum parkii butter - could be helpful for preventing or repairing signs of aging in theory, but there is no evidence that it actually works.

Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~1.5–2.3%

Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.55–1.35%

Can it cause trouble?

Irritancy

4 strong irritants: Parfum, Benzyl salicylate + 2 more — patch-test recommended

High risk

We flagged 15 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

CocoglyceridesHelp soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skinHigh~4.4–6.7%est.

ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.45%est.

Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.05–0.25%est.

Benzyl salicylateA fragrance. Is a likely irritantHigh~0.05–0.25%est.

Alpha-isomethyl iononeA fragrance. Potential allergen and can be irritatingHigh~0.05–0.2%est.

LinaloolA fragrance. Can be irritatingHigh~0.05–0.15%est.

Potassium cetyl phosphateHelps oil and water mix togetherMedium~3.3–5%est.

Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~2.9–4.3%est.

Argania spinosa kernel oilAn emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant propertiesMedium~0.9–1.35%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.Medium~0.45–1.05%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.4–0.95%est.

Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~0.4–0.9%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.1–0.45%est.

EthylhexylglycerinA preservativeMedium~0.1–0.45%est.

Sodium cocoyl glutamateHelps oil and water mix togetherMedium~0.15–0.65%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.55–1.35%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2.1–3.2%est.

Glycine soja oilA good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.2/5~0.45–1.05%est.

Alternatives

Cheaper, or higher on efficacy

U Beauty The SUPER Hydrator Face Moisturizer with Vitamin E + Antioxidants

Higher efficacy · 100/10064% match

$68.00

Dr. Barbara Sturm Glow Cream Crème Hydratante Éclat

Higher efficacy · 100/10063% match

$165.00

View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%

Formula

Irritation risk: Low

Plain old water

More about Water

Cocoglycerides~4.4–6.7%

Irritant · high

Irritation risk: High

Works for

CleansingMoisturizing

Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin

More about Cocoglycerides

Potassium cetyl phosphate~3.3–5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate

Coco-caprylate~2.9–4.3%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate

Cetearyl alcohol~2.1–3.2%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Hydrogenated palm glycerides~1.8–2.7%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin

More about Hydrogenated palm glycerides

Prunus amygdalus dulcis oil~1.5–2.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil

Glycerin~1.4–2%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Sorbitol~1–1.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol

Argania spinosa kernel oil~0.9–1.35%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the upper layer of the skin. Might have some weak anti-oxidant properties

More about Argania spinosa kernel oil

Butyrospermum parkii butter~0.55–1.35%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Glycine soja oil~0.45–1.05%

Key activeComedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Moisturizing

A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.

More about Glycine soja oil

Tocopheryl acetate~0.4–0.95%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Vitis vinifera seed oil~0.4–0.9%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil

Panthenol~0.35–0.8%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Vigna aconitifolia seed extract~0.35–0.75%

Formula

Irritation risk: Low

More about Vigna aconitifolia seed extract

Helianthus annuus seed oil~0.35–0.8%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Sodium hyaluronate~0.2–0.75%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Tocopherol~0.15–0.7%

Formula

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Phenoxyethanol~0.15–0.6%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Parfum~0.1–0.45%

Irritant · high

Irritation risk: High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum

Citric acid~0.1–0.45%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Ethylhexylglycerin~0.1–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Sodium cocoyl glutamate~0.15–0.65%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Sodium cocoyl glutamate

Benzyl alcohol~0.05–0.25%

Irritant · high

Irritation risk: High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol

Pantolactone~0.1–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Pantolactone

Benzyl salicylate~0.05–0.25%

Irritant · high

Irritation risk: High

A fragrance. Is a likely irritant

More about Benzyl salicylate

Alpha-isomethyl ionone~0.05–0.2%

Irritant · high

Irritation risk: High

A fragrance. Potential allergen and can be irritating

More about Alpha-isomethyl ionone

Linalool~0.05–0.15%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Ingredient list view

Water, Cocoglycerides, Potassium cetyl phosphate, Coco-caprylate, Cetearyl alcohol, Hydrogenated palm glycerides, Prunus amygdalus dulcis oil, Glycerin, Sorbitol, Argania spinosa kernel oil, Butyrospermum parkii butter, Glycine soja oil, Tocopheryl acetate, Vitis vinifera seed oil, Panthenol, Vigna aconitifolia seed extract, Helianthus annuus seed oil, Sodium hyaluronate, Tocopherol, Phenoxyethanol, Parfum, Citric acid, Ethylhexylglycerin, Sodium cocoyl glutamate, Benzyl alcohol, Pantolactone, Benzyl salicylate, Alpha-isomethyl ionone, Linalool

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German Drugstore50 ml

≈ $4.86

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	ISANAVital Night CreamYOUR PRODUCT	U BeautyThe SUPER Hydrator Face Moisturizer with Vitamin E + Antioxidants	Dr. Barbara SturmGlow Cream Crème Hydratante Éclat	EucerinHyaluron-Filler + Elasticity Night Cream
Match	—	64%	63%	63%
Price	≈ $4.86	$68.00≈ +$63.14	$165.00≈ +$160.14	$31.12≈ +$26.26
Shared key ingredients	—	7 of 9	6 of 9	6 of 9
Key difference	—	N-Prolyl Palmitoyl Tripeptide-56 Acetate	Lactobacillus/Portulaca Oleracea Ferment Extract	Caprylic/Capric Triglyceride
Irritancy	High	Medium	Medium	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredients included, "ISANA - Vital Night Cream" works well for moisturizing the skin. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. ISANA - Vital Night Cream ticks this box. Humectants in this product (panthenol, glycerin, pantolactone, sodium hyaluronate and sorbitol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Glycine soja oil, vitis vinifera seed oil, helianthus annuus seed oil, cetearyl alcohol and coco-caprylate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

An effective concentration of Panthenol (pro-vitamin B5) - about 0.35% - 0.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e

Irritation risk

This moisturizer contains a bunch of common irritants, including ingredients that do not provide any known benefit for the skin. It might not be the best choice if your skin is sensitive. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.