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iS Clinical Moisturizing Complex
iS Clinical

iS Clinical Moisturizing Complex

Efficacy91/100IrritancyMedium
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Works for

3 of 3 advertised claims delivered

Anti-oxidation
7 ingredients credited for this claim
Strong support

This product contains antioxidants (asiaticoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.3%
Triticum vulgare germ oilEffect: LowA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).~0.2–0.7%
Yeast extractUnder-dosedEffect: MediumHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.15–0.55%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.1–0.45%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.45–1.05%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.05–0.25%
Panax ginseng root extractEffect: Low, below effective doseA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating~0.15–0.6%
Moisturizing
17 ingredients credited for this claim
Strong support
What the product description says
“Intensively hydrating, antioxidant-rich Moisturizing Complex”
Source: Bluemercury

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, triticum vulgare germ oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

Pantothenic acidKey activeEffect: HighHelps attract water to the upper layer of the skin and may help reduce inflammation in skin~0.1–0.5%
Triticum vulgare germ oilKey active· EmollientEffect: HighA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).~0.2–0.7%
Asiatic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.35%
AsiaticosideKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.8–2.7%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.3–5%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~4.9–7.3%
Madecassic acidKey activeEffect: HighAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.35%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~1–1.5%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.15–0.55%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~2.6–3.9%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.05–0.25%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–2.2%
Yeast extractUnder-dosedEffect: HighHelps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin~0.15–0.55%
Simmondsia chinensis seed oilUnder-dosedEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.85–1.25%
Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.15–0.6%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.1–0.45%
Anti-aging
5 ingredients credited for this claim
Moderate support
What the product description says
“Reduces the appearance of fine lines and wrinkles”
Source: Bluemercury

This product contains asiaticoside. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

AsiaticosideKey activeEffect: MediumAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating~0.1–0.3%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~4.9–7.3%
Retinyl palmitateUnder-dosedEffect: MediumThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.3–0.75%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.1–0.45%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.05–0.25%

Can it cause trouble?

Irritancy
2 strong irritants: Alcohol denat., Retinyl palmitate
Medium risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Alcohol denat.Produces temporary toning effect. Can help dissolve other ingredients or preserve productsHigh~2.1–3.1%est.
Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.3–0.75%est.
MethyldihydrojasmonateUsed as a fragrance. Smells similar to jasmineHigh~0.15–0.5%est.
Panax ginseng root extractA plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritatingHigh~0.15–0.6%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.85–1.25%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.45–1.05%est.
Aluminum starch octenylsuccinateUsed to thicken the product's consistencyMedium~0.15–0.55%est.
Glyceryl dilaurateHelps oil and water mix togetherMedium~0.1–0.45%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.1–0.45%est.
AsiaticosideAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.3%est.
Asiatic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.35%est.
Madecassic acidAn active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritatingMedium~0.1–0.35%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.05–0.25%est.
Disodium edtaStabilizes the product formulationMedium~0.05–0.2%est.
1,2-hexanediolA preservativeMedium~0.05–0.2%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.05–0.25%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Triticum vulgare germ oilA good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).3/5~0.2–0.7%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Hyaluronic acid~4.9–7.3%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Glycerin~3.3–5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~2.6–3.9%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Alcohol denat.~2.1–3.1%
Irritant · high
Irritation risk
High

Produces temporary toning effect. Can help dissolve other ingredients or preserve products

More about Alcohol denat.
Dimethicone~1.8–2.7%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glyceryl stearate~1.5–2.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Peg-100 stearate~1.3–2%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Panthenol~1–1.5%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Simmondsia chinensis seed oil~0.85–1.25%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Tocopheryl acetate~0.45–1.05%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Retinyl palmitate~0.3–0.75%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-blemishExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate
Triticum vulgare germ oil~0.2–0.7%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidation

A good emoillient. Contains vitamin E which can help neutralise free radicals, however the oil is unstable. Avoid if you have gluten or wheat sensitivity (including food allergies).

More about Triticum vulgare germ oil
Aluminum starch octenylsuccinate~0.15–0.55%
Irritant · medium
Irritation risk
Medium

Used to thicken the product's consistency

More about Aluminum starch octenylsuccinate
Phospholipids~0.15–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Pantothenic acid~0.1–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-blemishReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and may help reduce inflammation in skin

More about Pantothenic acid
Methyldihydrojasmonate~0.15–0.5%
Irritant · high
Irritation risk
High

Used as a fragrance. Smells similar to jasmine

More about Methyldihydrojasmonate
Yeast extract~0.15–0.55%
Under-dosed
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatoryAnti-oxidationEvens skin tone

Helps attract water to the upper layer of the skin and might have some anti-oxidant and skin lightening properties. It can help calm down inflammation in skin

More about Yeast extract
Panax ginseng root extract~0.15–0.6%
Irritant · high
Irritation risk
High
Works for
Anti-inflammatoryAnti-oxidation

A plant extract that might have some anti-inflammatory properties, but solid evidence is lacking. It can be irritating

More about Panax ginseng root extract
Camellia sinensis leaf extract~0.1–0.45%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingEvens skin toneMoisturizingAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Ormenis multicaulis oil~0.1–0.35%
Formula
Irritation risk
Low
More about Ormenis multicaulis oil
Stearic acid~0.15–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Glyceryl dilaurate~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Glyceryl dilaurate
Carbomer~0.1–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Triethanolamine~0.1–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Asiaticoside~0.1–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationReduces irritationAnti-aging

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (madecasosside, asiatic acid and madecassic acid), asiaticoside has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiaticoside
Asiatic acid~0.1–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritationAnti-inflammatory

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and madecassic acid) asiatic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Asiatic acid
Madecassic acid~0.1–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingReduces irritation

An active compound of Centella Asiatica plant extract. In combination with other active compounds of Centella Asiatica extract (asiaticoside, madecasosside and asiatic acid), madecassic acid has been shown to be helpful in wound-healing, restoring skin barrier function and supporting collagen production in skin. It can, however, itself be irritating

More about Madecassic acid
Ascorbyl palmitate~0.05–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidation

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Disodium edta~0.05–0.2%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
1,2-hexanediol~0.05–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Caprylyl glycol~0.05–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ingredient list view

Water, Hyaluronic acid, Glycerin, Butylene glycol, Alcohol denat., Dimethicone, Glyceryl stearate, Peg-100 stearate, Panthenol, Simmondsia chinensis seed oil, Tocopheryl acetate, Retinyl palmitate, Triticum vulgare germ oil, Aluminum starch octenylsuccinate, Phospholipids, Pantothenic acid, Methyldihydrojasmonate, Yeast extract, Panax ginseng root extract, Camellia sinensis leaf extract, Ormenis multicaulis oil, Stearic acid, Glyceryl dilaurate, Carbomer, Triethanolamine, Asiaticoside, Asiatic acid, Madecassic acid, Ascorbyl palmitate, Disodium edta, 1,2-hexanediol, Caprylyl glycol

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Amazon USPrice as of 10/15/2026 03:00 GMT
$106.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
iS ClinicalMoisturizing ComplexYOUR PRODUCTDr.GRed Blemish Clear Soothing CreamFEEVHyper-Fortifying Barrier Cream DeluxeWish FormulaReparative - K Cream
Match—60%58%58%
Price$95.00$17.50−$77.50$13.68−$81.32$69.30−$25.70
Shared key ingredients—5 of 137 of 137 of 13
Key difference—NiacinamideMadecassosideMineral Oil
Irritancy Medium Medium Medium Medium
Drying alcohol Contains drying alcohol — Contains drying alcohol —
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Product summary

"iS Clinical - Moisturizing Complex" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol, glycerin, hyaluronic acid, soluble collagen and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (triticum vulgare germ oil, dimethicone, caprylyl glycol and glyceryl stearate) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer includes a form of retinoids (vitamin A) - retinyl palmitate 0.30% - 0.75%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
  • This formulation also includes actives derived from an extract of the Centella Asiatica plant (its other name is Gotu Kola): madecassic acid 0.10% - 0.35%, asiaticoside 0.10% - 0.30% and asiatic acid 0.10% - 0.35% The Centella Asiatica actives help strengthen and restore the skin barrier, decrease inflammation in skin and neutralize free radicals. They also can help to reduce scarring. The good news is that these actives work even in low concentrations.
  • This formulation also includes panthenol (pro-vitamin B5) at about 1.00% - 1.50% concentration. In this concentration, panthenol works effectively to improve the skin barrier and reduce inflammation.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 85.50$ up to 95.00$ in the United States, for 219.48CA$ in Canada, for 209.00A$ in Australia and from 78.00£ up to 141.57£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
    Efficacy of a New Topical Nano-hyaluronic Acid in Humansncbi.nlm.nih.gov
  2. 2
    Physiochemical properties and application of hyaluronic acid: a systematic reviewonlinelibrary.wiley.com
  3. 3
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  4. 4
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  5. 5
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  6. 6
    Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
iS Clinical Moisturizing Complex
iS ClinicalMoisturizing Complex
Buy on Amazon$106.00 · as of 10/15 03:00 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy on Amazon$106.00 · as of 10/15 03:00 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.