Eighth Day 2.0 The Regenerative Serum

Eighth Day 2.0 The Regenerative Serum

Efficacy100/100IrritancyMedium

Works for

Evens skin tone
Glycolic acid, Alanine + 2 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glycolic acid

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: alanine.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
AlanineEffect: LowAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.45–0.7%
TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.3–0.55%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.3–0.55%
Anti-aging
Sh-oligopeptide-2, Sh-polypeptide-1 + 15 more
Works well
What the product description says
“The patented formula addresses 10 visible signs of skin aging and is clinically proven to promote healthy, youthful-looking skin.”
Source: Eighth Day

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, glycolic acid.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, nonapeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, serine, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-9, threonine, tripeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Sh-oligopeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~4.1–5%
Sh-polypeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~3–3.7%
Sh-polypeptide-9Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.2–2.7%
Sh-polypeptide-11Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.8–2.2%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.5–1.9%
Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.3–1.6%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.1–1.3%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.95–1.15%
SerineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.65%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.5%
Nonapeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
ThreonineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.6%
Tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
Aminobutyric acidEffect: LowHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.3–0.55%
Thioctic acidEffect: Low~0.25–0.5%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.3–0.55%
Moisturizing
Sh-oligopeptide-2, Sh-polypeptide-1 + 33 more
Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: alanine, aminobutyric acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, nonapeptide-1, palmitoyl tetrapeptide-7, palmitoyl tripeptide-5, phytosphingosine, sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1, sh-polypeptide-11, sh-polypeptide-9, tripeptide-1

Sh-oligopeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~4.1–5%
Sh-polypeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~3–3.7%
Sh-polypeptide-9HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~2.2–2.7%
Sh-polypeptide-11HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.8–2.2%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.5–1.9%
Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.3–1.6%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~1.1–1.3%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.95–1.15%
PhytosphingosineHero· EmollientEffect: HighA type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect~0.35–0.6%
Nonapeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.5%
Tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.3–0.55%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.55–0.85%
Lysine hclKey activeEffect: High~0.5–0.75%
Histidine hclKey activeEffect: HighA salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function~0.45–0.65%
SerineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.45–0.65%
AlanineKey active· HumectantEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking~0.45–0.7%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.45–0.65%
ProlineKey activeEffect: Medium~0.4–0.65%
Glutamic acidKey active· HumectantEffect: HighAn amino-acid that helps attract water to the upper layer of the skin~0.35–0.6%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.3–0.6%
GlycineKey active· HumectantEffect: HighHelps to attract water to the upper layer of the skin and can help restore the skin barrier function~0.3–0.5%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.3–0.5%
IsoleucineKey activeEffect: HighAn amino acid that can help attract water to the upper layer of the skin and support skin's barrier function~0.3–0.5%
Sea whip extractKey activeEffect: HighMight help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin~0.3–0.5%
ThreonineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.3–0.6%
Aminobutyric acidKey active· HumectantEffect: HighHas been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing~0.3–0.55%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.5%
HoneyKey active· HumectantEffect: MediumHelps attract water to the skin and might have some anti-bacterial properties. Can be an allergen~0.3–0.5%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.1–0.2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~4.8–5.8%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.2–0.4%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.15–0.25%
LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.2–0.4%
NiacinamideUnder-dosedIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.3–0.55%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.35%
Exfoliation
Side benefit · Glycolic acid, Allantoin
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.25–0.5%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.2–0.35%
Anti-oxidation
Side benefit · Polygonum aviculare extract, Thioctic acid + 3 more
Works well

This product contains antioxidants (polygonum aviculare extract, thioctic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Polygonum aviculare extractKey activeEffect: HighA plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation~0.35–0.6%
Thioctic acidKey activeEffect: High~0.25–0.5%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.3–0.5%
TaurineEffect: LowCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness~0.3–0.55%
Sea whip extractEffect: LowMight help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin~0.3–0.5%

Can it cause trouble?

Irritancy
7 flagged ingredients
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.25–0.5%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~4.8–5.8%est.
TaurineCould be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectivenessMedium~0.3–0.55%est.
Polygonum aviculare extractA plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammationMedium~0.35–0.6%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.2–0.4%est.
1,2-hexanediolA preservativeMedium~0.05–0.15%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Pentylene glycol~4.8–5.8%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Sh-oligopeptide-2~4.1–5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-2
Sh-polypeptide-1~3–3.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-1
Sh-polypeptide-9~2.2–2.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-9
Sh-polypeptide-11~1.8–2.2%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-polypeptide-11
Acetyl hexapeptide-8~1.5–1.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Sh-oligopeptide-1~1.3–1.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1
Palmitoyl tripeptide-5~1.1–1.3%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Palmitoyl tetrapeptide-7~0.95–1.15%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Acetyl glutamine~0.65–0.95%
Formula
Sodium hyaluronate~0.55–0.85%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Lysine hcl~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Lysine hcl
Alanine~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingEvens skin tone

An amino-acid that helps to attract water to the upper layer of the skin and might help to lighten the skin, but solid evidence is lacking

More about Alanine
Histidine hcl~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

A salt of an amino-acid that helps attract water to the upper layer of the skin. Might be helpful in restoring the skin barrier function

More about Histidine hcl
Arginine~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Serine~0.45–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Serine
Proline~0.4–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing
More about Proline
Glutamic acid~0.35–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino-acid that helps attract water to the upper layer of the skin

More about Glutamic acid
Threonine~0.3–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Threonine
Valine~0.3–0.55%
Formula
Irritation risk
Low
More about Valine
Leucine~0.3–0.55%
Formula
Irritation risk
Low
More about Leucine
Glycine~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to attract water to the upper layer of the skin and can help restore the skin barrier function

More about Glycine
Isoleucine~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that can help attract water to the upper layer of the skin and support skin's barrier function

More about Isoleucine
Phenylalanine~0.3–0.55%
Formula
Irritation risk
Low
More about Phenylalanine
Taurine~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Anti-inflammatoryAnti-oxidationAnti-blemishEvens skin tone

Could be helpful in reducing inflammation in skin, evening out the skin tone and neutralizing free radicals, but more research is needed to confirm its effectiveness

More about Taurine
Glycerin~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hedychium coronarium root extract~0.3–0.5%
Formula
Tripeptide-1~0.3–0.55%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Tripeptide-1
Polygonum aviculare extract~0.35–0.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatory

A plant extract that contains a flavanol Juglanin. It can help neutralize free radicals in skin and reduce inflammation

More about Polygonum aviculare extract
Honey~0.3–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAntibacterial

Helps attract water to the skin and might have some anti-bacterial properties. Can be an allergen

More about Honey
Nonapeptide-1~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nonapeptide-1
Acetyl heptapeptide-4~0.3–0.5%
Formula
Phytosphingosine~0.35–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemish

A type of lipid that is naturally present in skin. It might help in repairing skin barrier function and has anti-bacterial effect

More about Phytosphingosine
Sea whip extract~0.3–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-inflammatory

Might help neutrlize free radicals, calm down inflammation, and attract water to the upper layer of the skin

More about Sea whip extract
Niacinamide~0.3–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Hydrolyzed hyaluronic acid~0.3–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Aminobutyric acid~0.3–0.55%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

Has been shown to support wound healing and skin barrier function when used topically in rats. Is likely to be effective in supporting skin's hydration and barrier function, but research for human skin is missing. Might have some anti-aging properties but the research is missing

More about Aminobutyric acid
Adenosine~0.3–0.5%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Thioctic acid~0.25–0.5%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-aging
More about Thioctic acid
Glycolic acid~0.25–0.5%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Bacillus/folic acid/soybean ferment extract~0.25–0.45%
Formula
Polysorbate 20~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Allantoin~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces irritationReduces rednessAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Caprylyl glycol~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Lecithin~0.2–0.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Butylene glycol~0.15–0.25%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
1,2-hexanediol~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Dextran~0.1–0.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Phenoxyethanol~0.1–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Xanthan gum~0.05–0.1%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ingredient list view

Water, Pentylene glycol, Sh-oligopeptide-2, Sh-polypeptide-1, Sh-polypeptide-9, Sh-polypeptide-11, Acetyl hexapeptide-8, Sh-oligopeptide-1, Palmitoyl tripeptide-5, Palmitoyl tetrapeptide-7, Acetyl glutamine, Sodium hyaluronate, Lysine hcl, Alanine, Histidine hcl, Arginine, Serine, Proline, Glutamic acid, Threonine, Valine, Leucine, Glycine, Isoleucine, Phenylalanine, Taurine, Glycerin, Hedychium coronarium root extract, Tripeptide-1, Polygonum aviculare extract, Honey, Nonapeptide-1, Acetyl heptapeptide-4, Phytosphingosine, Sea whip extract, Niacinamide, Hydrolyzed hyaluronic acid, Aminobutyric acid, Adenosine, Thioctic acid, Glycolic acid, Bacillus/folic acid/soybean ferment extract, Polysorbate 20, Allantoin, Caprylyl glycol, Lecithin, Butylene glycol, 1,2-hexanediol, Dextran, Phenoxyethanol, Ethylhexylglycerin, Xanthan gum

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Eighth Day
$225.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Eighth Day 2.0The Regenerative SerumYOUR PRODUCTSUNGBOON EDITORSilk Peptide EGF Intensive AmpoulenumbuzinNo.2 Rose PDRN Collagen 2x Plumping SerumArenciaDeep Water Surge Serum 30
Match—72%71%70%
Price$225.00$23.13−$201.87$21.67−$203.33$15.74−$209.26
Shared key ingredients—11 of 3211 of 3215 of 32
Key difference—Copper Tripeptide-1Copper Tripeptide-1Copper Tripeptide-1
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"Eighth Day 2.0 - The Regenerative Serum" is effective for: Anti-aging, Moisturizing, Exfoliation and Evens skin tone

Ingredient callouts

  • Ceramides (phytosphingosine 0.35% - 0.60%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
  • Peptides (nonapeptide-1 0.30% - 0.50%, tripeptide-1 0.30% - 0.55%, palmitoyl tetrapeptide-7 1.40% - 1.70%, palmitoyl tripeptide-5 1.50% - 1.90%, sh-polypeptide-9 2.20% - 2.70%, sh-polypeptide-1 3.00% - 3.70% and sh-oligopeptide-2 4.10% - 5.00%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.30% - 0.50%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Humectants (dextran 0.10% - 0.20%, aminobutyric acid 0.30% - 0.55%, hydrolyzed hyaluronic acid 0.30% - 0.50%, glycerin 0.30% - 0.60%, glycine 0.30% - 0.55%, glutamic acid 0.45% - 0.65%, arginine 0.45% - 0.70%, alanine 0.55% - 0.85% and sodium hyaluronate 0.80% - 1.20%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 27 studies and safety reviews.

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Eighth Day 2.0 The Regenerative Serum
Eighth Day 2.0The Regenerative Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.