Dr Grehen DeepRelief - Regenerating Cream

Dr Grehen DeepRelief - Regenerating Cream

Efficacy100/100IrritancyMedium

Works for

Moisturizing
Panthenol, Vaccinium macrocarpon seed oil + 11 more
Works well
What the product description says
“Deep Relief , Regenerating Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: fructose, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, butyrospermum parkii butter.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.95–1.45%
Vaccinium macrocarpon seed oilKey active· EmollientEffect: HighA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function~2.8–4.2%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.2–3.3%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.7%
Phenyl trimethiconeKey active· OcclusiveEffect: HighA type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture~1.2–1.8%
InulinKey activeEffect: HighHelps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking~0.3–0.7%
FructoseKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.2–0.8%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.75%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.1–0.4%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~3.7–5.5%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~0.05–0.1%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.55%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.15–0.7%
Anti-oxidation
Not advertised by the brand · Vaccinium macrocarpon seed oil, Butyrospermum parkii butter + 5 more
May help

This product contains antioxidants (vaccinium macrocarpon seed oil) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Vaccinium macrocarpon seed oilKey activeEffect: MediumA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function~2.8–4.2%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.2–3.3%
Olea europaea leaf extractEffect: LowA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing~0.35–0.8%
BisabololEffect: Low, below effective doseAn active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties~0.15–0.5%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.15–0.65%
Ascorbic acidUnder-dosedThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging~0.15–0.6%
TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.15–0.55%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Ascorbic acidThe most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of agingHigh~0.15–0.6%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.05–0.15%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.01–0.1%est.
Pentaerythrityl tetraisostearateUsed to create a thicker product consistencyMedium~5.1–7.7%est.
Vaccinium macrocarpon seed oilA plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier functionMedium~2.8–4.2%est.
Olea europaea leaf extractA plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missingMedium~0.35–0.8%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.15–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.5%est.
Peg-30 dipolyhydroxystearateHelps oil and water mix togetherMedium~0.1–0.4%est.
Dehydroacetic acidA preservativeMedium~0.05–0.1%est.
Peg-8Used to create a nice product consistencyMedium~0.05–0.1%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.2–3.3%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Pentaerythrityl tetraisostearate~5.1–7.7%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency

More about Pentaerythrityl tetraisostearate
Octyldodecanol~3.7–5.5%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Vaccinium macrocarpon seed oil~2.8–4.2%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plant oil that can help neutralize free radicals, soften the upper layer of the skin, and support skin's barrier function

More about Vaccinium macrocarpon seed oil
Butyrospermum parkii butter~2.2–3.3%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Glycerin~1.8–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Polyacrylate-13~1.5–2.2%
Formula
Irritation risk
Low

Used to create a thicker product consistency and stabilize the product formulation

More about Polyacrylate-13
Phenyl trimethicone~1.2–1.8%
Key active
Irritation risk
Low
Works for
Moisturizing

A type of silicone that can decrease loss of moisture from the skin surface. It helps create a nice product texture

More about Phenyl trimethicone
Panthenol~0.95–1.45%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Capparis spinosa fruit extract~0.55–1.3%
Formula
Opuntia ficus-indica extract~0.45–1.05%
Formula
Olea europaea leaf extract~0.35–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing

More about Olea europaea leaf extract
Maltodextrin~0.35–0.8%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Inulin~0.3–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-blemish

Helps attract water to the upper layer of the skin. Is claimed to support the growth of "good" bacteria in skin (as a "prebiotic"), but the research is lacking

More about Inulin
Fructose~0.2–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Fructose
Sodium hyaluronate~0.2–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Allantoin~0.15–0.7%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Ascorbyl palmitate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-aging

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Ascorbic acid~0.15–0.6%
Under-dosedIrritant · high
Irritation risk
High
Works for
Anti-oxidationEvens skin toneAnti-aging

The most well-researched antioxidant that works in skin. Helps neutralize free radicals supporting collagen production, helping to even out the skin tone and preventing early signs of aging

More about Ascorbic acid
Bisabolol~0.15–0.5%
Formula
Irritation risk
Low
Works for
Anti-inflammatoryReduces irritationAnti-oxidation

An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties

More about Bisabolol
Tocopherol~0.15–0.55%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Disodium edta~0.1–0.5%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Polyisobutene~0.1–0.5%
Formula
Irritation risk
Low

Used to improve the product consistency

More about Polyisobutene
Polysorbate 20~0.1–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Octyldodecyl xyloside~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing
More about Octyldodecyl xyloside
Peg-30 dipolyhydroxystearate~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-30 dipolyhydroxystearate
Beeswax~0.1–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Parfum~0.05–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Dehydroacetic acid~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Dehydroacetic acid
Benzyl alcohol~0.01–0.1%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Peg-8~0.05–0.1%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Citric acid~0.01–0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Aminomethyl propanol~0.01–0.05%
Formula
Irritation risk
Low

Used to adjust the pH in formulations

More about Aminomethyl propanol
Ingredient list view

Water, Pentaerythrityl tetraisostearate, Octyldodecanol, Vaccinium macrocarpon seed oil, Butyrospermum parkii butter, Glycerin, Polyacrylate-13, Phenyl trimethicone, Panthenol, Capparis spinosa fruit extract, Opuntia ficus-indica extract, Olea europaea leaf extract, Maltodextrin, Inulin, Fructose, Sodium hyaluronate, Allantoin, Ascorbyl palmitate, Ascorbic acid, Bisabolol, Tocopherol, Disodium edta, Polyisobutene, Polysorbate 20, Octyldodecyl xyloside, Peg-30 dipolyhydroxystearate, Beeswax, Parfum, Dehydroacetic acid, Benzyl alcohol, Peg-8, Citric acid, Aminomethyl propanol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Dr GrehenDeepRelief - Regenerating CreamYOUR PRODUCTMarudermHyaluronic Acid Moisturizer Face & Body CreamUriageCICA DAILY REPAIRING CREAM CONCENTRATECosmicaSensitive Balance Face Cream
Match—60%59%57%
Price—$21.99$21.89—
Shared key ingredients—6 of 115 of 114 of 11
Key difference—NiacinamideCaprylic/Capric TriglycerideAnhydroxylitol
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

Based on the ingredients included, "Dr Grehen - DeepRelief - Regenerating Cream" works well for moisturizing the skin. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Humectants in this product (panthenol, fructose, glycerin, sodium hyaluronate and peg-8) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (vaccinium macrocarpon seed oil, beeswax, butyrospermum parkii butter, phenyl trimethicone and octyldodecanol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This product also contains Vitamin C (Ascorbic Acid). It can be an effective active for anti-aging and evening out the skin tone, but in this moisturizer it is used for stabilizing other ingredients in the formulation. In this concentration (0.15% - 0.60%) it cannot have a noticeable benefit for the skin.
  • An effective concentration of Panthenol (pro-vitamin B5) - about 0.95% - 1.45%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: vitamin e, vitamin c and allantoin

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 16 studies and safety reviews.

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Dr Grehen DeepRelief - Regenerating Cream
Dr GrehenDeepRelief - Regenerating Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.