Dr. Brandt Do Not Age Time Defying Cream

Dr. Brandt Do Not Age Time Defying Cream

Efficacy87/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Trifluoroacetyl tripeptide-2, Caprylic/capric triglyceride + 15 more
Strong evidence
What the product description says
“- 100% reported skin felt hydrated, moisturized, and nurtured”
Source: Sephora

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dextran, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: trifluoroacetyl tripeptide-2

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~6.2–7.6%
Vitis vinifera seed oilKey active· EmollientEffect: HighA great emollient that can also have anti-oxidant properties~0.15–0.3%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.8–2.2%
Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.1–2.5%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.25–0.5%
Trifluoroacetyl tripeptide-2HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.8–1.15%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.5–1.8%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~2.4–3%
PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.1–0.2%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.2–1.5%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~0.7–1.05%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.4–0.6%
Dibutyl adipate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~3.3–4%
Alaria esculenta extractUnder-dosedEffect: MediumWorks as a humectant helping to attract water to the upper layer of the skin and might be effective as an anti-oxidant.~0.3–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.3%
Anti-aging
Trifluoroacetyl tripeptide-2, Vitis vinifera seed extract + 4 more
Moderate evidence
What the product description says
“Do Not Age® time defying cream is a rich cream that visibly firms and smooths lines and wrinkles for a more sculpted appearance.”
Source: Dr. Brandt

This product contains trifluoroacetyl tripeptide-2, vitis vinifera seed extract. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Trifluoroacetyl tripeptide-2Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.25–0.45%
Vitis vinifera seed extractKey activeEffect: MediumA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.15–0.3%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.1–2.5%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.3%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%
Alaria esculenta extractEffect: Low, below effective doseWorks as a humectant helping to attract water to the upper layer of the skin and might be effective as an anti-oxidant.~0.3–0.5%
Anti-oxidation
Not advertised by the brand · Vitis vinifera seed extract, Butyrospermum parkii butter + 4 more
Strong evidence

This product contains antioxidants (vitis vinifera seed extract) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Vitis vinifera seed extractKey activeEffect: HighA plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation~0.15–0.3%
Butyrospermum parkii butterEffect: LowA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.1–2.5%
Vitis vinifera seed oilEffect: LowA great emollient that can also have anti-oxidant properties~0.15–0.3%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.45–0.65%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.3%
Alaria esculenta extractEffect: Low, below effective doseWorks as a humectant helping to attract water to the upper layer of the skin and might be effective as an anti-oxidant.~0.3–0.5%

Can it cause trouble?

Irritancy
2 strong irritants: Geranium maculatum oil, Lavandula hybrida oil
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Geranium maculatum oilAn essential oil. Can be irritatingHigh~0.2–0.4%est.
Lavandula hybrida oilPlant extract that can be irritating and is a known allergenHigh~0.25–0.45%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~6.2–7.6%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~2.4–3%est.
Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~1–1.2%est.
Sodium cocoyl glutamateHelps oil and water mix togetherMedium~0.6–0.9%est.
BhtA preservativeMedium~0.45–0.7%est.
Disodium edtaStabilizes the product formulationMedium~0.45–0.65%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.4–0.6%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Juniperus virginiana oilCedarwood oil. Used as a fragrance. Can be irritatingMedium~0.25–0.4%est.
Vitis vinifera seed oilA great emollient that can also have anti-oxidant propertiesMedium~0.15–0.3%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.1–2.5%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.8–1.15%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~6.2–7.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Cetyl babassuate~4.4–5.4%
Formula
Dibutyl adipate~3.3–4%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Dibutyl adipate
Macadamia ternifolia seed oil~2.4–3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Butyrospermum parkii butter~2.1–2.5%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Glycerin~1.8–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclopentasiloxane~1.5–1.8%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Glyceryl stearate~1.2–1.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Sodium acrylates copolymer~1–1.2%
Irritant · medium
Irritation risk
Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer
Cetearyl alcohol~0.8–1.15%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Stearic acid~0.7–1.05%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Sodium cocoyl glutamate~0.6–0.9%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sodium cocoyl glutamate
Bht~0.45–0.7%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Disodium edta~0.45–0.65%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Tocopherol~0.45–0.65%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Phenoxyethanol~0.4–0.65%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Caprylyl glycol~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Alaria esculenta extract~0.3–0.5%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

Works as a humectant helping to attract water to the upper layer of the skin and might be effective as an anti-oxidant.

More about Alaria esculenta extract
Dextran~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Trifluoroacetyl tripeptide-2~0.25–0.45%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Trifluoroacetyl tripeptide-2
Zinc ricinoleate~0.25–0.45%
Formula
Juniperus virginiana oil~0.25–0.4%
Irritant · medium
Irritation risk
Medium

Cedarwood oil. Used as a fragrance. Can be irritating

More about Juniperus virginiana oil
Geranium maculatum oil~0.2–0.4%
Irritant · high
Irritation risk
High

An essential oil. Can be irritating

More about Geranium maculatum oil
Lavandula hybrida oil~0.25–0.45%
Irritant · high
Irritation risk
High

Plant extract that can be irritating and is a known allergen

More about Lavandula hybrida oil
Pogostemon cablin oil~0.2–0.35%
Formula
Vetiveria zizanoides root oil~0.15–0.3%
Formula
Linum usitatissimum seed extract~0.15–0.3%
Formula
Camellia sinensis leaf extract~0.15–0.3%
Under-dosed
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Vitis vinifera seed extract~0.15–0.3%
Key active
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingAntibacterial

A plant extract that contains resveratrol and other anti-oxidant compounds that can help neutralize free radicals, reduce inflammation in skin and even out its tone. Can be also used to stabilize the product formulation

More about Vitis vinifera seed extract
Vitis vinifera seed oil~0.15–0.3%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

A great emollient that can also have anti-oxidant properties

More about Vitis vinifera seed oil
Phospholipids~0.1–0.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids
Carbomer~0.1–0.15%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Ingredient list view

Water, Caprylic/capric triglyceride, Cetyl babassuate, Dibutyl adipate, Macadamia ternifolia seed oil, Butyrospermum parkii butter, Glycerin, Cyclopentasiloxane, Glyceryl stearate, Sodium acrylates copolymer, Cetearyl alcohol, Stearic acid, Sodium cocoyl glutamate, Bht, Disodium edta, Tocopherol, Phenoxyethanol, Caprylyl glycol, Chlorphenesin, Alaria esculenta extract, Dextran, Trifluoroacetyl tripeptide-2, Zinc ricinoleate, Juniperus virginiana oil, Geranium maculatum oil, Lavandula hybrida oil, Pogostemon cablin oil, Vetiveria zizanoides root oil, Linum usitatissimum seed extract, Camellia sinensis leaf extract, Vitis vinifera seed extract, Vitis vinifera seed oil, Phospholipids, Carbomer

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$66.00
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$132.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Dr. BrandtDo Not Age Time Defying CreamYOUR PRODUCTThe outsetRestorative Niacinamide Night CreamLululunPrecious CreamDRMTLGYPeptide Night Cream
Match—55%55%54%
Price$66.00—$34.64−$31.36$25.23−$40.77
Shared key ingredients—6 of 106 of 106 of 10
Key difference—NiacinamideDimethiconeCeramide Ap
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

"Dr. Brandt - Do Not Age Time Defying Cream" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Dr. Brandt - Do Not Age Time Defying Cream ticks this box. Dextran, glycerin and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Vitis vinifera seed oil, butyrospermum parkii butter, caprylic/capric triglyceride, cetearyl alcohol and cyclopentasiloxane in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • We like that this moisturizer contains peptides (trifluoroacetyl tripeptide-2 0.25% - 0.45%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 81.99$ up to 132.00$ in the United States, from 70.07CA$ up to 158.40CA$ in Canada, for 158.04A$ in Australia and from 85.83£ up to 107.00£ in the United Kingdom.

For a detailed price comparison: click here.

Dr. Brandt Do Not Age Time Defying Cream
Dr. BrandtDo Not Age Time Defying Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.