Works for:
based on ingredients and %- Anti-aging
- Evens skin tone
- Moisturizing
- Anti-blemish
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 1
Key actives
Product Summary
"Dermalist - Age Defying MultiComplex" is effective for: Anti-blemish, Anti-aging, Exfoliation, Evens skin tone and Moisturizing
Ingredient callouts
- A good concentration of Niacinamide (4.20% - 5.10%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
- This product contains an effective form of Retinoids (vitamin A): retinol 0.65% - 0.95%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Peptides (acetyl tetrapeptide-2 0.25% - 0.50% and acetyl octapeptide-3 0.25% - 0.50%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- An effective concentration of Panthenol (pro-vitamin B5) - about 2.30% - 2.80%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
- Humectants (acetyl octapeptide-3 0.25% - 0.50%, hyaluronic acid 0.30% - 0.55%, sodium hyaluronate 0.30% - 0.60%, panthenol 2.30% - 2.80% and glycerin 4.60% - 5.70%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Anti-aging
What does the product description say?
For firmer, brighter, more youthful skin Targets visible signs of ageing Stimulates elastin & collagen production Vegan & cruelty free Australian made & owned Defy time with Dermalist’s new Age Defying Multicomplex – the ultimate serum for firmer, brighter, plumper looking skin.
Source: N/A
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl octapeptide-3, acetyl tetrapeptide-2, resveratrol.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide, retinol. These ingredients is used for treating acne and can have a noticeable effect.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Anti-oxidation
This product contains antioxidants (resveratrol, retinol, thioctic acid) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - ficus carica fruit extract, ginkgo biloba leaf extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
A plant extract that can help neutralize free radicals. The concentrations typically used in cosmetics are too small to have an effect
A fruit extract that is used to add a fragrance to the product. It might have some antioxidant properties
Carrot extract. Might have anti-oxidant properties and be used to add orange color
A plant extract that might have some anti-oxidant and anti-inflammatory properties but evidence for effectiveness in skin is missing
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect
Evens skin tone
What does the product description say?
For total skin renewal, this advanced cosmeceutical serum also contains Vitamin C, Hyaluronic Acid, Niacinamide and potent antioxidants to plump skin & improve skin tone, texture and radiance leaving skin looking clearer, vibrant and more youthful at every age.
Source: N/A
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
In addition, this product contains niacinamide. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: resveratrol.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps neutralize free radicals in skin and might help reduce fine lines and wrinkles, as well as even out the skin tone
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Moisturizing
What does the product description say?
Follow with usual skincare routine including moisturiser and broad-spectrum UVA / UVB sunscreen.
Source: N/A
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, hyaluronic acid.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl octapeptide-3, acetyl tetrapeptide-2, niacinamide, panthenol
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps attract water to the upper layer of the skin and can help improve skin barrier function
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An emollient that helps soften the skin. Can increase penetration of other ingredients
Helps preserve products and creates a nice product texture
Used as a fragrance. Can be irritating
A plant extract that can help neutralize free radicals in skin and attract water to its upper layer
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
Might be somewhat helpful in reducing hyperpigmentation and neutralizing free radicals but its typical concentration in a product is too low for having an effect
Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
Dermalist Age Defying MultiComplex | Current | $179.00 | |
 pH formula MD AGE Active Recovery | 73% | $780.00 | |
PCA SKIN Intensive Age Refining Treatment 0.5 Percent Pure Retinol Night | 73% | $101.00 | |
 Olay Masks | Overnight Gel Mask | Hydrating | 72% | $8.00 | |
Skin Nutritions Double Strength Retinol Night Repair Serum | 72% | $20.00 | |
 YEOUTH Clear Skin Essentials | 71% | $92.75 |
Key Actives
Potential irritants
Comedogenic ingredients
All ingredients
Ingredient list view
Water, Glycerin, Niacinamide, Sodium ascorbyl phosphate, Panthenol, Cetearyl alcohol, Cetearyl glucoside, Squalane, Olea europaea fruit oil, Citric acid, Retinol, Cellulose acetate butyrate, Tricaprylin, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Pichia/resveratrol ferment extract, Resveratrol, Xanthan gum, Sodium hyaluronate, Hyaluronic acid, Ethylhexylglycerin, Acetyl octapeptide-3, Acetyl tetrapeptide-2, Tocopherol, Thioctic acid, Citric acid, Tasmannia lanceolata fruit extract, Syzygium luehmannii fruit extract, Kunzea pomifera fruit extract, Cucumis sativus fruit extract, Ficus carica fruit extract, Ginkgo biloba leaf extract, Lycium barbarum fruit extract, Punica granatum fruit extract, Santalum acuminatum fruit extract, Olea europaea leaf extract, Camellia sinensis leaf extract, Carica papaya fruit extract, Acacia victoriae fruit extract, Unknown, Citrus aurantifolia oil, Unknown, Helianthus annuus seed oil, Daucus carota sativa root extract, Phenoxyethanol, Caprylyl glycol, Citrus aurantium dulcis oil, Cedrus atlantica bark oil, Lavandula angustifolia oil, Cymbopogon martini oil, Rosa damascena flower oil, Vanilla planifolia fruit extract
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- Safety Assessment of Pentaerythrityl Tetra-Di-t-Butyl Hydroxyhydrocinnamate as Used in Cosmetics
- Skin permeation and antioxidant efficacy of topically applied resveratrol
- Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
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- Hyaluronic acid: A key molecule in skin aging
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- Vitamin E in dermatology
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- Lycium barbarum polysaccharide protects human keratinocytes against UVB-induced photo-damage
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- Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egypt
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- Air oxidation increases skin irritation from fragrance terpenes
- Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts