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Derma E Anti-Wrinkle Renewal Cream
Derma E

Derma E Anti-Wrinkle Renewal Cream

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Anti-aging
Retinol, Bakuchiol
Works well
What the product description says
“Anti-Wrinkle Renewal Cream”
Source: Derma E

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, bakuchiol.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.8%
Moisturizing
Panthenol, Carthamus tinctorius seed oil + 9 more
Works well
What the product description says
“This clinically proven renewal cream delivers targeted wrinkle correction with weightless hydration.”
Source: Derma E

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, simmondsia chinensis seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.15–0.65%
Carthamus tinctorius seed oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and might help calm down inflammation~5.9–8.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.6–5.4%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~2.1–3.2%
Glyceryl stearate seKey activeEffect: MediumUsed to stabilize the product formulations and works as an emollient~1.7–2.5%
Persea gratissima oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and could be helpful in repairing its barrier function~1–1.5%
Sesamum indicum seed oilKey active· EmollientEffect: HighA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function~0.85–1.25%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.5–1.2%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.45–1.1%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.6–3.9%
AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.4%
Anti-oxidation
Bakuchiol, Retinol + 2 more
Works well

This product contains antioxidants (bakuchiol, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.8%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
Carthamus tinctorius seed oilEffect: LowAn emollient that helps soften the skin and might help calm down inflammation~5.9–8.8%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.15–0.6%
Evens skin tone
Retinol, Bakuchiol
Works well
What the product description says
“This rich, skin-renewing cream contains both retinol and bakuchiol, two powerful ingredients that work together to visibly refine your skin's tone and texture.”
Source: SmallFlower

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains bakuchiol. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.8%
Anti-blemish
Side benefit · Retinol, Bakuchiol + 1 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.35–0.8%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.4%
Exfoliation
Side benefit · Retinol, Microcrystalline cellulose + 1 more
Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.3–0.75%
Microcrystalline celluloseEffect: Low~1.5–2.2%
AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.4%

Can it cause trouble?

Irritancy
2 strong irritants: Retinol, Parfum
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.3–0.75%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.01–0.1%est.
Persea gratissima oilAn emollient that helps soften the skin and could be helpful in repairing its barrier functionMedium~1–1.5%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.45–1.1%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.35–0.8%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.15–0.6%est.
EthylhexylglycerinA preservativeMedium~0.05–0.15%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Glyceryl stearate seUsed to stabilize the product formulations and works as an emollient2/5~1.7–2.5%est.
Alternatives
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Carthamus tinctorius seed oil~5.9–8.8%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the skin and might help calm down inflammation

More about Carthamus tinctorius seed oil
Glycerin~3.6–5.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Stearic acid~2.6–3.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Cetyl alcohol~2.1–3.2%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Glyceryl stearate se~1.7–2.5%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

Used to stabilize the product formulations and works as an emollient

More about Glyceryl stearate se
Microcrystalline cellulose~1.5–2.2%
Formula
Irritation risk
Low
Works for
Exfoliation
More about Microcrystalline cellulose
Cellulose gum~1.2–1.8%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Persea gratissima oil~1–1.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and could be helpful in repairing its barrier function

More about Persea gratissima oil
Sesamum indicum seed oil~0.85–1.25%
Key active
Irritation risk
Low
Works for
Moisturizing

A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function

More about Sesamum indicum seed oil
Helianthus annuus seed oil~0.5–1.2%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Simmondsia chinensis seed oil~0.45–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Retinol~0.3–0.75%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-oxidationAnti-agingExfoliationMattifyingAnti-blemishEvens skin tone

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Bakuchiol~0.35–0.8%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-agingEvens skin toneAnti-inflammatoryAnti-blemishAnti-oxidation

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Panthenol~0.15–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Tocopheryl acetate~0.15–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Allantoin~0.1–0.4%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryReduces irritationAnti-blemishReduces rednessExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Polysorbate 20~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Sodium hydroxide~0.05–0.3%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Phenoxyethanol~0.05–0.25%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Parfum~0.01–0.1%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Ingredient list view

Water, Carthamus tinctorius seed oil, Glycerin, Stearic acid, Cetyl alcohol, Glyceryl stearate se, Microcrystalline cellulose, Cellulose gum, Persea gratissima oil, Sesamum indicum seed oil, Helianthus annuus seed oil, Simmondsia chinensis seed oil, Retinol, Bakuchiol, Panthenol, Tocopheryl acetate, Allantoin, Polysorbate 20, Sodium hydroxide, Phenoxyethanol, Ethylhexylglycerin, Parfum

Compare prices

Retailers ranked by price — lowest first.

Amazon USPrice as of 11/13 15:21 GMT
$19.50
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SmallFlower4 oz
$20.35
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Derma E
$20.50
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Ulta4 oz
$20.50
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EAnti-Wrinkle Renewal CreamYOUR PRODUCTNaturiumRetinol Complex CreamMoshPM MoisturiserGood MoleculesGentle Retinol Cream
Match—78%78%77%
Price$20.50$15.99−$4.51$28.06+$7.56$7.97−$12.53
Shared key ingredients—4 of 94 of 94 of 9
Key difference—Linoleic AcidCeramide ApCaprylic/Capric Triglyceride
Irritancy Medium Medium Medium Medium
Drying alcohol————
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Product summary

Based on the ingredient list, "Derma E - Anti-Wrinkle Renewal Cream" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol and glycerin) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (carthamus tinctorius seed oil, persea gratissima oil, sesamum indicum seed oil, helianthus annuus seed oil and cetyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • this moisturizer contains Bakuchiol (0.50% - 1.10%). It is a plant extract that is has a similar effect to that of Retinoids but with less irritation. Bakuchiol can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation.
  • This moisturizer contains an effective form of Retinoids (vitamin A): retinol 0.35% - 0.85%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily. Because of the irritation risk of Retinoids, we recommend to have another, retinoid-free moisturizer in your routine to use on the alternate days or when your skin feels dry.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: allantoin and vitamin e

Irritation risk

There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.

Price

The product retails from 20.50$ up to 23.95$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Protein and oil composition of sesame seeds (Sesamum indicum, L.) grown in the Gizan area of Saudi Arabiatandfonline.com
  3. 3
    Triglyceride composition of Sesamum indicum seed oilonlinelibrary.wiley.com
  4. 4
    Seed oil content and fatty acid composition in East African sesame (Sesamum indicum L.) accessions evaluated over 3 yearssciencedirect.com
  5. 5
    Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
  6. 6
    Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
Derma E Anti-Wrinkle Renewal Cream
Derma EAnti-Wrinkle Renewal Cream
Buy at Derma E$20.50$19.50as of 11/13 15:21 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Derma E$20.50$19.50as of 11/13 15:21 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.