Derma E Anti-Aging Regenerative Serum

Derma E Anti-Aging Regenerative Serum

Efficacy100/100IrritancyHigh

Works for

Exfoliation
Retinol, Glycolic acid
Works well
What the product description says
“Resurface skin without the flakes.”
Source: Derma E

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid, retinol.

RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–1.35%
Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.15–0.55%
Anti-aging
Retinol, Bakuchiol + 2 more
Works well
What the product description says
“This beginner-friendly retinol serum helps visibly smooth texture, firm skin, and reduces the look of fine lines.”
Source: Derma E

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol, bakuchiol, glycolic acid.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–1.35%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.45–1.1%
Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.15–0.55%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.2–1.7%
Moisturizing
Panthenol, Glycerin + 9 more
Works well
What the product description says
“A balanced blend of dermatologist-recommended Retinol combined with Bakuchiol & Glycolic Acid delivers effective renewal with less irritation, while barrier-supporting Vitamin E helps keep skin supple and hydrated.”
Source: Derma E

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: helianthus annuus seed oil, persea gratissima oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.4–0.9%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–5.9%
Coco-caprylateKey active· EmollientEffect: MediumAn emollient that softens skin and creates a nice product texture~3.4–5.1%
Capryloyl glycerin/sebacic acid copolymerKey activeEffect: MediumHelps soften the upper layer of the skin~1.8–2.7%
Diheptyl succinateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin and creates a nice product finish on the skin~1.4–2.2%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~0.15–0.55%
Persea gratissima oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and could be helpful in repairing its barrier function~0.15–0.55%
Sesamum indicum seed oilKey active· EmollientEffect: HighA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function~0.1–0.45%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.2–1.7%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.35–0.85%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.2–0.8%
Anti-oxidation
Side benefit · Camellia sinensis leaf extract, Retinol + 2 more
Works well

This product contains antioxidants (bakuchiol, retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - camellia sinensis leaf extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.2–1.7%
RetinolKey activeEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–1.35%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.45–1.1%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~1–1.5%
Evens skin tone
Side benefit · Retinol, Bakuchiol + 2 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.

In addition, this product contains bakuchiol, glycolic acid. This ingredient (ingredients) might help reduce hyperpigmentation, but the effect, if any, is likely to be small.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–1.35%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.45–1.1%
Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.15–0.55%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.2–1.7%
Anti-blemish
Side benefit · Retinol, Bakuchiol + 2 more
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.

In addition, this product contains bakuchiol. It can help in reducing blemishes, even though it is less effective.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycolic acid

RetinolHeroEffect: HighTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating~0.55–1.35%
BakuchiolKey activeEffect: HighA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation~0.45–1.1%
Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid~0.15–0.55%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.2–1.7%

Can it cause trouble?

Irritancy
7 strong irritants: Retinol, Lavandula angustifolia oil + 5 more — patch-test recommended
High risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
RetinolTwo steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritatingHigh~0.55–1.35%est.
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh~0.15–0.55%est.
Lavandula angustifolia oilAn essential oil. Potential allergen and can be irritating. It has some anti-bacterial propertiesHigh~0.15–0.55%est.
Salvia officinalis oil—High~0.05–0.3%est.
Citrus aurantium dulcis peel oilAn essentil oil from orange peel. Potential allergen and can be irritatingHigh~0.1–0.35%est.
Camphor—High~0.1–0.35%est.
CitralA fragrance with a lemon scent. A likely irritantHigh~0.05–0.25%est.
Mentha viridis leaf oilUsed as a fragrance and can be irritatingHigh~0.05–0.25%est.
Coco-caprylateAn emollient that softens skin and creates a nice product textureMedium~3.4–5.1%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~1–1.5%est.
BakuchiolA plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritationMedium~0.45–1.1%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.15–0.65%est.
Persea gratissima oilAn emollient that helps soften the skin and could be helpful in repairing its barrier functionMedium~0.15–0.55%est.
EthylhexylglycerinA preservativeMedium~0.05–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Coco-caprylate~3.4–5.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that softens skin and creates a nice product texture

More about Coco-caprylate
Xanthan gum~1.8–2.7%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Capryloyl glycerin/sebacic acid copolymer~1.8–2.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Capryloyl glycerin/sebacic acid copolymer
Diheptyl succinate~1.4–2.2%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin and creates a nice product finish on the skin

More about Diheptyl succinate
Camellia sinensis leaf extract~1.2–1.7%
Key active
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Tocopheryl acetate~1–1.5%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Retinol~0.55–1.35%
Hero · Anti-aging, Evens skin tone, Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-agingEvens skin toneAnti-blemishMattifyingExfoliationAnti-oxidation

Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating

More about Retinol
Bakuchiol~0.45–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationAnti-inflammatoryAnti-blemishEvens skin toneAnti-aging

A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation

More about Bakuchiol
Panthenol~0.4–0.9%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Glyceryl stearate~0.35–0.85%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Glyceryl stearate citrate~0.2–0.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Potassium cetyl phosphate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Glycolic acid~0.15–0.55%
Key activeIrritant · high
Irritation risk
High
Works for
ExfoliationAnti-agingEvens skin toneAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Sodium hydroxide~0.15–0.55%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Lavandula angustifolia oil~0.15–0.55%
Irritant · high
Irritation risk
High

An essential oil. Potential allergen and can be irritating. It has some anti-bacterial properties

More about Lavandula angustifolia oil
Helianthus annuus seed oil~0.15–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Persea gratissima oil~0.15–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient that helps soften the skin and could be helpful in repairing its barrier function

More about Persea gratissima oil
Sesamum indicum seed oil~0.1–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function

More about Sesamum indicum seed oil
Polysorbate 20~0.1–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Salvia officinalis oil~0.05–0.3%
Irritant · high
Beta-caryophyllene~0.05–0.2%
Formula
Eucalyptol~0.05–0.25%
Formula
Irritation risk
Low
More about Eucalyptol
Citrus aurantium dulcis peel oil~0.1–0.35%
Irritant · high
Irritation risk
High

An essentil oil from orange peel. Potential allergen and can be irritating

More about Citrus aurantium dulcis peel oil
L-alpha-pinene~0.05–0.25%
Formula
Irritation risk
Low
More about L-alpha-pinene
Camphor~0.1–0.35%
Irritant · high
Irritation risk
High
More about Camphor
Citral~0.05–0.25%
Irritant · high
Irritation risk
High

A fragrance with a lemon scent. A likely irritant

More about Citral
Geranyl acetate~0.05–0.2%
Formula
Mentha viridis leaf oil~0.05–0.25%
Irritant · high
Irritation risk
High

Used as a fragrance and can be irritating

More about Mentha viridis leaf oil
Citronellal~0.05–0.2%
Formula
Irritation risk
Low
More about Citronellal
Phenoxyethanol~0.05–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Glycerin, Coco-caprylate, Xanthan gum, Capryloyl glycerin/sebacic acid copolymer, Diheptyl succinate, Camellia sinensis leaf extract, Tocopheryl acetate, Retinol, Bakuchiol, Panthenol, Glyceryl stearate, Glyceryl stearate citrate, Potassium cetyl phosphate, Glycolic acid, Sodium hydroxide, Lavandula angustifolia oil, Helianthus annuus seed oil, Persea gratissima oil, Sesamum indicum seed oil, Polysorbate 20, Salvia officinalis oil, Beta-caryophyllene, Eucalyptol, Citrus aurantium dulcis peel oil, L-alpha-pinene, Camphor, Citral, Geranyl acetate, Mentha viridis leaf oil, Citronellal, Phenoxyethanol, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EAnti-Aging Regenerative SerumYOUR PRODUCTDr Dennis GrossAdvanced Retinol + Ferulic Texture Renewal Serum PacketteSKIN&LABretinol repair serumImage skincareAGELESS+ retinol treatment crème 1.2% retinol complex
Match—90%84%83%
Price$15.99$67.15+$51.16$13.99−$2.00$60.00+$44.01
Shared key ingredients—5 of 94 of 96 of 9
Key difference—Salicylic AcidSh-Polypeptide-22Acetyl Tetrapeptide-2
Irritancy High Medium Medium High
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

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Derma E Anti-Aging Regenerative Serum
Derma EAnti-Aging Regenerative Serum

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