Derma E Advanced Peptides and Collagen Eye Cream

Derma E Advanced Peptides and Collagen Eye Cream

Efficacy87/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
17 ingredients credited for this claim
Strong support
What the product description says
“Advanced Peptides and Collagen Eye Cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tripeptide-38, panthenol

Palmitoyl tripeptide-38HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–1.4%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.4–0.95%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.1–0.5%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~3.8–5.7%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–1.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.3–6.5%
CollagenKey activeEffect: MediumCannot penetrate the skin barrier so is not particularly useful in skincare products~0.2–0.8%
Macadamia ternifolia seed oilKey active· EmollientEffect: MediumPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients~2.7–4.1%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.7–2.6%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.3–1.9%
Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~1.4–2.1%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.1–3.2%
Hydroxypropyl cyclodextrin· EmollientEffect: LowUsed to stabilize product formulations and help soften the upper layer of the skin~1.1–1.6%
Simmondsia chinensis seed oilUnder-dosedEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~0.15–0.55%
AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.1–0.35%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.7%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.5%
Anti-aging
5 ingredients credited for this claim
Moderate support
What the product description says
“Advanced Peptides and Collagen Eye Cream”
From product name

This product contains acetyl hexapeptide-8, palmitoyl tripeptide-38. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–1.1%
Palmitoyl tripeptide-38Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.6–1.4%
Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.7%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.15–0.65%
Anti-oxidation
Not advertised by the brand · 6 ingredients credited for this claim
Moderate support

This product contains antioxidants (pinus pinaster bark extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Pinus pinaster bark extractKey activeEffect: MediumA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)~0.4–0.9%
Aesculus hippocastanum seed extractEffect: LowPlant extract. Might have some anti-oxidant properties. Can be irritating~0.15–0.55%
TocopherolUnder-dosedEffect: HighPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.3–0.7%
Camellia sinensis leaf extractUnder-dosedEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.15–0.5%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.3–0.75%
Ascorbyl palmitateEffect: Low, below effective doseBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.~0.15–0.65%

Can it cause trouble?

Irritancy
1 strong irritant: Hamamelis virginiana bark/leaf extract
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Aesculus hippocastanum seed extractPlant extract. Might have some anti-oxidant properties. Can be irritatingHigh~0.15–0.55%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~3.8–5.7%est.
Macadamia ternifolia seed oilPlant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredientsMedium~2.7–4.1%est.
Hydroxypropyl cyclodextrinUsed to stabilize product formulations and help soften the upper layer of the skinMedium~1.1–1.6%est.
Pinus pinaster bark extractA plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)Medium~0.4–0.9%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.3–0.75%est.
Ascorbyl palmitateBeing a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.Medium~0.15–0.65%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~0.15–0.55%est.
Potassium sorbateA preservativeMedium~0.05–0.3%est.
EthylhexylglycerinA preservativeMedium~0.01–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.3–6.5%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Caprylic/capric triglyceride~3.8–5.7%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Macadamia ternifolia seed oil~2.7–4.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Plant oil from nuts that helps soften the upper layer of the skin. Contains a high concentration of oleic acid that can weaken skin's barrier function and increase water-loss while enhancing penetration of other ingredients

More about Macadamia ternifolia seed oil
Stearic acid~2.1–3.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Cetyl alcohol~1.7–2.6%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Glyceryl stearate citrate~1.4–2.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate
Glyceryl stearate~1.3–1.9%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Hydroxypropyl cyclodextrin~1.1–1.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to stabilize product formulations and help soften the upper layer of the skin

More about Hydroxypropyl cyclodextrin
Palmitoyl tripeptide-38~0.6–1.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-38
Acetyl hexapeptide-8~0.5–1.1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Panthenol~0.4–0.95%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Pinus pinaster bark extract~0.4–0.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin tone

A plant extract that might help neutralize free radicals and reduce hyperpigmentation, but evidence of effectiveness of topical application is lacking. It can be an INCI name for the trademarked ingredient Pycnogenol (but could also be a different type of this plant's bark extract)

More about Pinus pinaster bark extract
Acacia seyal gum extract~0.35–0.75%
Formula
Plant derived
Not recognized
Collagen~0.2–0.8%
Key active
Irritation risk
Low
Works for
Moisturizing

Cannot penetrate the skin barrier so is not particularly useful in skincare products

More about Collagen
Tocopheryl acetate~0.3–0.75%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Tocopherol~0.3–0.7%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-agingAnti-inflammatory

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Ascorbyl palmitate~0.15–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Anti-agingAnti-oxidation

Being a lipid soluble form of vitamin C, it is more stable and can penetrate the skin better than L-Ascorbic acid. It is effective in protecting the skin from free radicals, as well as evening the skin tone, but is less effective in stimulating collagen production compared to L-Ascorbic acid.

More about Ascorbyl palmitate
Hamamelis virginiana bark/leaf extract~0.15–0.65%
Irritant · high
Aesculus hippocastanum seed extract~0.15–0.55%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation

Plant extract. Might have some anti-oxidant properties. Can be irritating

More about Aesculus hippocastanum seed extract
Camellia sinensis leaf extract~0.15–0.5%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingEvens skin toneMoisturizingAnti-blemish

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Chamomilla recutita flower~0.1–0.45%
Formula
Simmondsia chinensis seed oil~0.15–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Allantoin~0.1–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingReduces rednessAnti-blemishReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin
Dimethicone~0.1–0.5%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Xanthan gum~0.1–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Potassium sorbate~0.05–0.3%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Sodium hydroxide~0.05–0.2%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Phenoxyethanol~0.05–0.2%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Ethylhexylglycerin~0.01–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Ingredient list view

Water, Glycerin, Caprylic/capric triglyceride, Macadamia ternifolia seed oil, Stearic acid, Cetyl alcohol, Glyceryl stearate citrate, Glyceryl stearate, Hydroxypropyl cyclodextrin, Palmitoyl tripeptide-38, Acetyl hexapeptide-8, Panthenol, Pinus pinaster bark extract, Acacia seyal gum extract, Unknown, Collagen, Tocopheryl acetate, Tocopherol, Ascorbyl palmitate, Hamamelis virginiana bark/leaf extract, Aesculus hippocastanum seed extract, Camellia sinensis leaf extract, Chamomilla recutita flower, Simmondsia chinensis seed oil, Allantoin, Dimethicone, Xanthan gum, Potassium sorbate, Sodium hydroxide, Phenoxyethanol, Ethylhexylglycerin

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Amazon USPrice as of 10/9/2026 21:07 GMT
$24.99
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Derma E
$29.95
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Derma EAdvanced Peptides and Collagen Eye CreamYOUR PRODUCTBaleaBeauty Expert Day Cream 3% Peptid-Solution 1% EctoinDrunk ElephantC-Tango Multivitamin Eye CreamNaturiumMulti-Peptide Eye Cream
Match—52%50%50%
Price$24.99$8.49−$16.50$60.28+$35.29$15.99−$9.00
Shared key ingredients—5 of 107 of 104 of 10
Key difference—Acetyl Dipeptide-1 Cetyl EsterDipeptide-2Palmitoyl Tetrapeptide-7
Irritancy Medium Low Medium Medium
Drying alcohol————
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Product summary

Based on the ingredient list, "Derma E - Advanced Peptides and Collagen Eye Cream" can work well for skin moisturization. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Acetyl hexapeptide-8, panthenol and glycerin in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Caprylic/capric triglyceride, dimethicone, cetyl alcohol, macadamia ternifolia seed oil and glyceryl stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

  • This moisturizer also contains Peptides (acetyl hexapeptide-8 0.50% - 1.10% and palmitoyl tripeptide-38 0.60% - 1.40%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • An effective concentration of Panthenol (pro-vitamin B5) - about 0.40% - 0.95%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: jojoba oil, allantoin and vitamin e

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

About the brand

According to Cruelty-Free Kitty "Derma E" is cruelty free and so is its parent company.

Price

The product retails from 18.67$ up to 29.95$ in the United States and for 31.45A$ in Australia.

For a detailed price comparison: click here.

Derma E Advanced Peptides and Collagen Eye Cream
Derma EAdvanced Peptides and Collagen Eye Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.