Naturium Multi-Peptide Eye Cream

Naturium Multi-Peptide Eye Cream

Efficacy87/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Acetyl hexapeptide-8, Palmitoyl tripeptide-1 + 17 more
Strong evidence
What the product description says
“Multi-peptide blend hydrates and helps smooth appearance of fine lines and wrinkles”
Source: Naturium

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, pantolactone.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: simmondsia chinensis seed oil, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5, panthenol

Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.75–1.15%
Palmitoyl tripeptide-1Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.55–0.85%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.35–0.65%
PantolactoneKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.05–0.1%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~4.2–5.1%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.35–0.65%
Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.2–0.35%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~2.3–2.8%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.9–6%
Palmitoyl tetrapeptide-7Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–1%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.5–1.9%
Dunaliella salina extractKey activeEffect: MediumA green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin~0.4–0.65%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~2.8–3.4%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.9–2.3%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.3–0.6%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.25–0.5%
Palmitic acid· EmollientEffect: LowAn emollient that is naturally present in skin and helps soften it~1.1–1.4%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.25–0.5%
Anti-aging
Acetyl hexapeptide-8, Palmitoyl tetrapeptide-7 + 2 more
Moderate evidence
What the product description says
“Multi-peptide blend hydrates and helps smooth appearance of fine lines and wrinkles”
Source: Naturium

This product contains acetyl hexapeptide-8, palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.75–1.15%
Palmitoyl tetrapeptide-7Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.65–1%
Palmitoyl tripeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.55–0.85%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.45–0.7%

Can it cause trouble?

Irritancy
13 flagged ingredients
Medium risk
We flagged 13 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~4.2–5.1%est.
HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.35–0.65%est.
Sorbitan oleateHelps oil and water mix togetherMedium~0.35–0.6%est.
Aluminum starch octenylsuccinateUsed to thicken the product's consistencyMedium~0.3–0.55%est.
1,2-hexanediolA preservativeMedium~0.25–0.45%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.25–0.5%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.25–0.45%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.25–0.4%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.2–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.1–0.2%est.
EthylhexylglycerinA preservativeMedium~0.1–0.15%est.
Potassium sorbateA preservativeMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Sorbitan oleateHelps oil and water mix together2/5~0.35–0.6%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.9–6%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Simmondsia chinensis seed oil~4.2–5.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Stearic acid~2.8–3.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Squalane~2.3–2.8%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Glyceryl stearate~1.9–2.3%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cetyl alcohol~1.5–1.9%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Stearyl alcohol~1.4–1.7%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Palmitic acid~1.1–1.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that is naturally present in skin and helps soften it

More about Palmitic acid
Acetyl hexapeptide-8~0.75–1.15%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Palmitoyl tetrapeptide-7~0.65–1%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tetrapeptide-7
Palmitoyl tripeptide-1~0.55–0.85%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-1
Palmitoyl tripeptide-5~0.45–0.7%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Dunaliella salina extract~0.4–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidation

A green micro-algae extract that might help neutralize free radicals in skin, but solid evidence is lacking. It helps to soften the upper layer of the skin

More about Dunaliella salina extract
Panthenol~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Sodium hyaluronate~0.35–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Hydroxyacetophenone~0.35–0.65%
Irritant · medium
Irritation risk
Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone
Sorbitan oleate~0.35–0.6%
Comedogenic 2/5Irritant · medium
Irritation risk
Medium
Comedogenicity
2/5
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan oleate
Aluminum starch octenylsuccinate~0.3–0.55%
Irritant · medium
Irritation risk
Medium

Used to thicken the product's consistency

More about Aluminum starch octenylsuccinate
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.25–0.5%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Phenoxyethanol~0.25–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Butylene glycol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
1,2-hexanediol~0.25–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Boron nitride~0.25–0.45%
Formula
Irritation risk
Low

Helps to absord oil and evenly disperse other ingredients (for example, pigment) in product formulation

More about Boron nitride
Caprylyl glycol~0.25–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Tocopheryl acetate~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Isohexadecane~0.3–0.6%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Acrylates/c10-30 alkyl acrylate crosspolymer~0.25–0.4%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Sodium hydroxide~0.2–0.4%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Polysorbate 80~0.2–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Carbomer~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Sodium lactate~0.2–0.35%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Polysorbate 20~0.15–0.3%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Citric acid~0.1–0.2%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ethylhexylglycerin~0.1–0.15%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Pantolactone~0.05–0.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Pantolactone
Sodium benzoate~0.05–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Potassium sorbate~0.05–0.1%
Irritant · medium
Irritation risk
Medium

A preservative

More about Potassium sorbate
Ingredient list view

Water, Glycerin, Simmondsia chinensis seed oil, Stearic acid, Squalane, Glyceryl stearate, Cetyl alcohol, Stearyl alcohol, Palmitic acid, Acetyl hexapeptide-8, Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1, Palmitoyl tripeptide-5, Dunaliella salina extract, Panthenol, Sodium hyaluronate, Hydroxyacetophenone, Sorbitan oleate, Aluminum starch octenylsuccinate, Acrylamide/sodium acryloyldimethyltaurate copolymer, Phenoxyethanol, Butylene glycol, 1,2-hexanediol, Boron nitride, Caprylyl glycol, Tocopheryl acetate, Isohexadecane, Chlorphenesin, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium hydroxide, Polysorbate 80, Carbomer, Sodium lactate, Polysorbate 20, Citric acid, Ethylhexylglycerin, Pantolactone, Sodium benzoate, Potassium sorbate

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Amazon USPrice as of 10/23/2026 06:26 GMT
$15.99
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$16.00
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
NaturiumMulti-Peptide Eye CreamYOUR PRODUCTNEOGEN X SUR.MEDICV.Biome Advanced Eye CreamBIOHEAL BOHProbioderm 3D Lifting Eye & Wrinkle CreamAwake BeautyRise & Reset Eye Cream
Match—60%56%56%
Price$15.99$25.16+$9.17$38.62+$22.63—
Shared key ingredients—8 of 116 of 116 of 11
Key difference—Copper Tripeptide-1Acetyl Tetrapeptide-5Caprylic/Capric Triglyceride
Irritancy Medium Medium Medium Low
Drying alcohol————
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Product summary

"Naturium - Multi-Peptide Eye Cream" is a well-rounded moisturizing product. This moisturizer uses a good combo of humectants and emollients. These both types of ingredients are essentials for improving the skin hydration and keeping the skin barrier healthy. Acetyl hexapeptide-8, panthenol, glycerin, pantolactone and sodium hyaluronate in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Emollients in this formulation (palmitoyl tetrapeptide-7, palmitoyl tripeptide-1, simmondsia chinensis seed oil, squalane and cetyl alcohol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • This moisturizer also contains Peptides (palmitoyl tripeptide-5 0.45% - 0.70%, palmitoyl tripeptide-1 0.55% - 0.85%, palmitoyl tetrapeptide-7 0.65% - 1.00% and acetyl hexapeptide-8 0.75% - 1.15%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that they are helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 16.00$ up to 23.00$ in the United States and from 18.00£ up to 126.00£ in the United Kingdom.

For a detailed price comparison: click here.

Naturium Multi-Peptide Eye Cream
NaturiumMulti-Peptide Eye Cream

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.