Comfort Zone Skin Regimen Polypeptide Rich Cream
Works for
2 of 2 advertised claims delivered
Moisturizing22 ingredients credited for this claimStrong support
“Skin Regimen Polypeptide Rich Cream”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
carnosine, glycerin.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, glycine soja oil.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl tetrapeptide-2, palmitoyl tripeptide-5
Anti-aging5 ingredients credited for this claimModerate support
“Ideal for those with wrinkles, signs of ageing, stress and fatigue.”
This product contains acetyl tetrapeptide-2, carnosine, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.
Anti-oxidationNot advertised by the brand · 6 ingredients credited for this claimStrong support
This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
Can it cause trouble?
Irritancy3 strong irritants: Juniperus phoenicea gum extract, Copaifera officinalis resin + 1 more — patch-test recommendedHigh risk
Comedogenic2 ingredients rated 2 or more on the 0–5 pore-clogging scale2 flagged
User reviews
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Ingredients
Filter by role to see what each ingredient is doing.
Water~45–55%
Butyrospermum parkii butter~5.5–6.7%
- Irritation risk
- Low
- Comedogenicity
- 3/5
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
More about Butyrospermum parkii butterGlycerin~4.2–5.1%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinC10-18 triglycerides~3.2–3.9%
- Irritation risk
- Low
Helps soften the skin and attract water to its upper layer. Helps create nice product texture
More about C10-18 triglyceridesPentylene glycol~2.4–2.9%
- Irritation risk
- Medium
Used to preserve products, dissolve other ingredients and create a nice product texture
More about Pentylene glycolDicaprylyl carbonate~2–2.4%
- Irritation risk
- Low
Helps products spread more easily and works as an emollient to soften skin
More about Dicaprylyl carbonateBehenyl alcohol~1.7–2.1%
- Irritation risk
- Low
Non-drying alcohol that helps water and oil mix together. Also serves as an emollient
More about Behenyl alcoholCetyl alcohol~1.5–1.8%
- Irritation risk
- Low
A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together
More about Cetyl alcoholGlyceryl stearate citrate~1.2–1.4%
- Irritation risk
- Low
Helps oil and water mix together while softening the upper layer of the skin
More about Glyceryl stearate citrateOrbignya oleifera seed oil~1–1.2%
- Irritation risk
- Low
A plant oil that can help soften the upper layer of the skin. Might be helpful in calming down inflammation in skin
More about Orbignya oleifera seed oilOleyl erucate~0.7–1.05%
- Irritation risk
- Low
Helps soften the upper layer of the skin and create a nice product texture
More about Oleyl erucateCetearyl isononanoate~0.55–0.85%
- Irritation risk
- Low
An emollient that softens the skin and helps prevent moisture loss.
More about Cetearyl isononanoateMicrocrystalline cellulose~0.6–0.95%
Acetyl tetrapeptide-2~0.45–0.65%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Acetyl tetrapeptide-2Phenoxyethanol~0.4–0.65%
- Irritation risk
- Low
A preservative. It helps prevent bacterial growth in cosmetic products
More about PhenoxyethanolIsostearyl alcohol~0.45–0.65%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Isostearyl alcoholMica~0.45–0.65%
- Irritation risk
- Low
Creates an illusion of smoother and more radiant skin tone. Adds shimmer to the skin by reflecting light
More about MicaEthylhexyl stearate~0.35–0.65%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Ethylhexyl stearateCi 77891~0.35–0.6%
- Irritation risk
- Low
Titanium dioxide~0.4–0.6%
- Irritation risk
- Low
Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin
More about Titanium dioxideJuniperus virginiana oil~0.25–0.45%
- Irritation risk
- Medium
Cedarwood oil. Used as a fragrance. Can be irritating
More about Juniperus virginiana oilPropanediol~0.25–0.5%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolButylene glycol cocoate~0.25–0.45%
- Irritation risk
- Medium
Helps oil and water mix together
More about Butylene glycol cocoateHexyldecanol~0.25–0.45%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about HexyldecanolHexyldecyl laurate~0.25–0.45%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Hexyldecyl laurateCaprylyl glycol~0.25–0.45%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolAristotelia chilensis fruit extract~0.2–0.4%
- Irritation risk
- High
A plant extract that might have some anti-oxidant properties. Can be used as a fragrance
More about Aristotelia chilensis fruit extractCarnosine~0.2–0.4%
- Irritation risk
- Low
A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage
More about CarnosineSpinacia oleracea leaf extract~0.2–0.4%
- Irritation risk
- Medium
A plant extract that might have some anti-oxidant properties
More about Spinacia oleracea leaf extractCellulose gum~0.25–0.45%
- Irritation risk
- Low
Used to create thicker product consistency and stabilize emulsions
More about Cellulose gumTaraxacum officinale rhizome/root extract~0.2–0.35%
- Irritation risk
- High
A plant extract that might have some anti-oxidant properties
More about Taraxacum officinale rhizome/root extractJuniperus phoenicea gum extract~0.2–0.4%
Agar~0.25–0.4%
- Irritation risk
- Medium
Polysaccharide derived from seaweed. Used to create a thicker product consistency and might help attract water to the upper layer of the skin
More about AgarXanthan gum~0.25–0.4%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Xanthan gumCitric acid~0.2–0.4%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidEthylhexylglycerin~0.2–0.4%
Tocopherol~0.25–0.45%
- Irritation risk
- Low
Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself
More about TocopherolSodium phytate~0.2–0.4%
Copaifera officinalis resin~0.2–0.4%
Glycine soja oil~0.2–0.4%
- Irritation risk
- Medium
- Comedogenicity
- 2/5
A good emollient that helps soften the skin and helps repair its barrier function. It can clog pores if used in high concentrations.
More about Glycine soja oilTephrosia purpurea seed extract~0.2–0.4%
- Irritation risk
- Medium
A plant extract that might help attract water to the upper layer of the skin. The manufacturer claims that it can help "break down cortisol production in skin production in skin cells", but actual benefits to the skin are not clear
More about Tephrosia purpurea seed extractEthylcellulose~0.2–0.35%
- Irritation risk
- Low
Palmitoyl tripeptide-5~0.15–0.3%
- Irritation risk
- Low
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
More about Palmitoyl tripeptide-5Aniba rosodora wood oil~0.15–0.25%
Ci 77491~0.15–0.3%
- Irritation risk
- Low
A red colorant made of iron oxide. Typically is not irritating
More about Ci 77491Iron oxides~0.15–0.25%
- Irritation risk
- Low
An umbrella term for the following three colorants: CI 77491, CI 77492, CI 77499. They might be able to offer some protection against visible light, but the degree of the protection is not clear
More about Iron oxidesSodium benzoate~0.1–0.25%
Potassium sorbate~0.15–0.25%
Ingredient list view
Water, Butyrospermum parkii butter, Glycerin, C10-18 triglycerides, Pentylene glycol, Dicaprylyl carbonate, Behenyl alcohol, Cetyl alcohol, Glyceryl stearate citrate, Orbignya oleifera seed oil, Oleyl erucate, Cetearyl isononanoate, Microcrystalline cellulose, Acetyl tetrapeptide-2, Phenoxyethanol, Isostearyl alcohol, Mica, Ethylhexyl stearate, Ci 77891, Titanium dioxide, Juniperus virginiana oil, Propanediol, Butylene glycol cocoate, Hexyldecanol, Hexyldecyl laurate, Caprylyl glycol, Aristotelia chilensis fruit extract, Carnosine, Spinacia oleracea leaf extract, Cellulose gum, Taraxacum officinale rhizome/root extract, Juniperus phoenicea gum extract, Agar, Xanthan gum, Citric acid, Ethylhexylglycerin, Tocopherol, Sodium phytate, Copaifera officinalis resin, Glycine soja oil, Tephrosia purpurea seed extract, Ethylcellulose, Palmitoyl tripeptide-5, Aniba rosodora wood oil, Ci 77491, Iron oxides, Sodium benzoate, Potassium sorbate
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| Comfort ZoneSkin Regimen Polypeptide Rich CreamYOUR PRODUCT | Skin RegimenPolypeptide Rich Cream | Peter Thomas RothPEPTIDE 21 WRINKLE RESIST MOISTURISER - Day care | StriVectinMulti-Action Restorative Cream | |
|---|---|---|---|---|
| Match | — | 72% | 56% | 55% |
| Price | $81.64 | $76.15−$5.49 | — | $45.00−$36.64 |
| Shared key ingredients | — | 10 of 10 | 4 of 10 | 5 of 10 |
| Key difference | — | — | Tripeptide-1 | Caprylic/Capric Triglyceride |
| Irritancy | High | High | Medium | Low |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
"Comfort Zone - Skin Regimen Polypeptide Rich Cream" has a good moisturizing formula. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (carnosine, glycerin and caprylyl glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (glycine soja oil, oleyl erucate, orbignya oleifera seed oil, butyrospermum parkii butter and c10-18 triglycerides) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.
Ingredient callouts
- We like that this moisturizer contains peptides (palmitoyl tripeptide-5 0.15% - 0.30% and acetyl tetrapeptide-2 0.45% - 0.65%). There are many different kind of peptides and they are naturally present in our skin. They all are a combination of amino-acids. Some of them work as natural anti-biotics, promote wound-healing and production of collagen. The science is still not settled on how effective peptides in skincare are, but it is very likely that they have a benefit. Peptides might help restore the skin barrier and fight the signs of aging. At the very least, peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Irritation risk
We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 61.75£ in the United Kingdom.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 6 studies and safety reviews.
- 1
- 2
- 3
- 4
- 5Vitamin E in dermatologyncbi.nlm.nih.gov
- 6Vitamin E and Skin Healthlpi.oregonstate.edu
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