CLEARSTEM Skincare

CLEARSTEM Skincare CELLRENEW - Collagen Stem Cell Serum

Name: CLEARSTEM Skincare - CELLRENEW - Collagen Stem Cell Serum
Brand: CLEARSTEM Skincare

Efficacy87/100IrritancyHigh

See all ingredients

Works for

Anti-aging

Gluconolactone, Sh-oligopeptide-1 + 5 more

Works well

What the product description says

“→ Support collagen production”

Source: ClearStem

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains gluconolactone.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: sh-oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

GluconolactoneKey activeEffect: HighA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.95–1.2%

Sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

Aloe barbadensis leaf juiceEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~6–7.4%

Zinc pcaEffect: LowA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.4%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.4%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.2–0.35%

Evens skin tone

Gluconolactone, Camellia sinensis leaf extract + 1 more

Works well

What the product description says

“→ Fade discoloration”

Source: ClearStem

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: gluconolactone

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Moisturizing

Sh-oligopeptide-1, Panthenol + 24 more

Works well

What the product description says

“CELLRENEW® was developed for those wanting total skin regeneration that helps with breakouts, hydration, and the post-blemish marks that can stick around far too long.”

Source: ClearStem

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, betaine.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol, sh-oligopeptide-1

Sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.4–0.6%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.3–0.5%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3–3.6%

ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~1.5–1.8%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~0.8–1.2%

IsomaltKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.55%

Ganoderma lucidum extractKey activeEffect: HighHelps attract water to the upper layer of the skin~0.25–0.45%

Magnesium pcaKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.25–0.4%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%

Tremella fuciformis sporocarp extractKey active· HumectantEffect: HighMushroom extract that helps attract water to the upper layer of the skin~0.25–0.45%

Copper pcaKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.25–0.45%

PhospholipidsKey activeEffect: MediumEmollients that are naturaly present in skin. In addition, they help water and oil mix together in the product~0.25–0.45%

Glucosyl hesperidinKey active· HumectantEffect: MediumMight be able to neutralize free radicals in skin. Also works as a humectant~0.25–0.45%

Zinc pcaKey active· HumectantEffect: HighA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.4%

BetaineKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and improves the product texture~0.2–0.35%

Hippophae rhamnoides fruit oilKey activeEffect: MediumA plant oil that might somewhat help to neutralize free radicals. It could be irritating~0.2–0.4%

Aloe barbadensis leaf juice· HumectantEffect: LowTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~6–7.4%

Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~1.3–1.6%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.6–0.9%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.4–0.6%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%

AllantoinUnder-dosedHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Anti-blemish

Gluconolactone, Zinc pca + 3 more

Not delivered

What the product description says

“CELLRENEW® was developed for those wanting total skin regeneration that helps with breakouts, hydration, and the post-blemish marks that can stick around far too long.”

Source: ClearStem

This product contains ingredients (gluconolactone, zinc pca) that could help reduce blemishes and clogged pores in theory, but there is not enough evidence that they actually work.

GluconolactoneEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.95–1.2%

Zinc pcaEffect: MediumA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.2–0.4%

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Exfoliation

Side benefit · Gluconolactone, Allantoin + 1 more

Works well

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: gluconolactone.

AllantoinEffect: Low, below effective doseHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.3–0.55%

Anti-oxidation

Side benefit · Gluconolactone, Epilobium angustifolium flower/leaf/stem extract + 6 more

May help

This product contains antioxidants (epilobium angustifolium flower/leaf/stem extract, gluconolactone) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

GluconolactoneKey activeEffect: MediumA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.95–1.2%

Epilobium angustifolium flower/leaf/stem extractKey activeEffect: MediumA plant extract that might contain antioxidants~0.25–0.45%

Tremella fuciformis sporocarp extractEffect: LowMushroom extract that helps attract water to the upper layer of the skin~0.25–0.45%

Glucosyl hesperidinEffect: LowMight be able to neutralize free radicals in skin. Also works as a humectant~0.25–0.45%

Hippophae rhamnoides fruit oilEffect: LowA plant oil that might somewhat help to neutralize free radicals. It could be irritating~0.2–0.4%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.25–0.4%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.25–0.45%

Can it cause trouble?

Irritancy

7 strong irritants: Citrus nobilis peel oil, Menthoxypropanediol + 5 more — patch-test recommended

High risk

We flagged 26 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Citrus nobilis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.2–0.4%est.

MenthoxypropanediolUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.

Boswellia carterii oilUsed as a fragrance. Can be irritatingHigh~0.2–0.35%est.

Hippophae rhamnoides fruit oilA plant oil that might somewhat help to neutralize free radicals. It could be irritatingHigh~0.2–0.4%est.

Epilobium angustifolium flower/leaf/stem extractA plant extract that might contain antioxidantsHigh~0.25–0.45%est.

Tasmannia lanceolata fruit/leaf extract—High~0.25–0.45%est.

Arnica montana flower extractA plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skinHigh~0.2–0.4%est.

Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.2–0.4%est.

Jasminum officinale flower extractFragrance. Can be irritatingHigh~0.15–0.25%est.

LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.15–0.3%est.

LinaloolA fragrance. Can be irritatingHigh~0.15–0.25%est.

Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~6–7.4%est.

GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.95–1.2%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~0.8–1.2%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.6–0.9%est.

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymerA gelling agent that thickens the product consistency and leaves the skin with a velvety finishMedium~0.35–0.65%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.4–0.6%est.

Sodium acrylates copolymerUsed to create a thicker product consistencyMedium~0.2–0.35%est.

Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.2–0.35%est.

Ganoderma lucidum extractHelps attract water to the upper layer of the skinMedium~0.25–0.45%est.

Serenoa serrulata fruit extractA plant extract that might help calm down inflammation in skin but evidence of effectiveness is lackingMedium~0.25–0.45%est.

Potassium sorbateA preservativeMedium~0.25–0.45%est.

T-butyl alcoholUsed to dissolve other ingredients and to improve smell of products. It could be irritatingMedium~0.2–0.4%est.

Sorbic acidA preservativeMedium~0.2–0.35%est.

Leuconostoc/radish root ferment filtrateA preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determineMedium~0.15–0.3%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.15%est.

Comedogenic

Clean of flagged comedogenic ingredients

None flagged

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Aloe barbadensis leaf juice~6–7.4%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingReduces rednessReduces irritationAntibacterialAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice

Propanediol~4.1–5%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Glycerin~3–3.6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Isopentyldiol~2.2–2.7%

Formula

Irritation risk: Low

Helps dissolve other ingredients in a formulation

More about Isopentyldiol

Polyglyceryl-4 caprate~1.8–2.1%

Formula

Irritation risk: Low

Works for

Cleansing

More about Polyglyceryl-4 caprate

Arginine~1.5–1.8%

Key active

Irritation risk: Low

Works for

Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine

Dicaprylyl ether~1.3–1.6%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether

Gluconolactone~0.95–1.2%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-agingEvens skin toneExfoliationAnti-blemishAnti-oxidation

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone

Caprylic/capric triglyceride~0.8–1.2%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Caprylyl glycol~0.6–0.9%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Allantoin~0.3–0.55%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces rednessReduces irritationAnti-blemishExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Sh-oligopeptide-1~0.4–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Sh-oligopeptide-1

Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer~0.35–0.65%

Irritant · medium

Irritation risk: Medium

A gelling agent that thickens the product consistency and leaves the skin with a velvety finish

More about Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer

Pentylene glycol~0.4–0.6%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Polyacrylate crosspolymer-6~0.35–0.6%

Formula

Irritation risk: Low

More about Polyacrylate crosspolymer-6

Isomalt~0.3–0.55%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Isomalt

Panthenol~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Glucosyl hesperidin~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Might be able to neutralize free radicals in skin. Also works as a humectant

More about Glucosyl hesperidin

Citrus nobilis peel oil~0.2–0.4%

Irritant · high

Irritation risk: High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus nobilis peel oil

Sodium gluconate~0.2–0.35%

Formula

Irritation risk: Low

Helps stabilize product formulations

More about Sodium gluconate

Sodium acrylates copolymer~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Used to create a thicker product consistency

More about Sodium acrylates copolymer

Glycyrrhiza glabra rhizome/root extract~0.2–0.35%

Formula

Irritation risk: Low

More about Glycyrrhiza glabra rhizome/root extract

Menthoxypropanediol~0.2–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Menthoxypropanediol

Lactic acid~0.2–0.35%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

MoisturizingEvens skin toneExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid

Betaine~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Betaine

Lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Boswellia carterii oil~0.2–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance. Can be irritating

More about Boswellia carterii oil

Hippophae rhamnoides fruit oil~0.2–0.4%

Key activeIrritant · high

Irritation risk: High

Works for

MoisturizingAnti-oxidationAnti-inflammatory

A plant oil that might somewhat help to neutralize free radicals. It could be irritating

More about Hippophae rhamnoides fruit oil

Lactobacillus/salix purpurea bark ferment extract~0.2–0.4%

Formula

Irritation risk: Low

More about Lactobacillus/salix purpurea bark ferment extract

Ganoderma lucidum extract~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Ganoderma lucidum extract

Tremella fuciformis sporocarp extract~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Mushroom extract that helps attract water to the upper layer of the skin

More about Tremella fuciformis sporocarp extract

Sodium hyaluronate~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Zinc hydrolyzed hyaluronate~0.25–0.4%

Formula

Irritation risk: Low

More about Zinc hydrolyzed hyaluronate

Serenoa serrulata fruit extract~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatory

A plant extract that might help calm down inflammation in skin but evidence of effectiveness is lacking

More about Serenoa serrulata fruit extract

Epilobium angustifolium flower/leaf/stem extract~0.25–0.45%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that might contain antioxidants

More about Epilobium angustifolium flower/leaf/stem extract

Argania spinosa callus culture extract~0.25–0.45%

Formula

Irritation risk: Low

More about Argania spinosa callus culture extract

Potassium sorbate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

A preservative

More about Potassium sorbate

Tasmannia lanceolata fruit/leaf extract~0.25–0.45%

Irritant · high

Irritation risk: High

More about Tasmannia lanceolata fruit/leaf extract

Arnica montana flower extract~0.2–0.4%

Irritant · high

Irritation risk: High

A plant extract that can be irritating. It can have some anti-bacterial properties, but there are no evidence of a beneficial effect for skin

More about Arnica montana flower extract

Camellia sinensis leaf extract~0.25–0.45%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Phospholipids~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Emollients that are naturaly present in skin. In addition, they help water and oil mix together in the product

More about Phospholipids

Magnesium pca~0.25–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Magnesium pca

Zinc pca~0.2–0.4%

Key active

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishAnti-oxidationAnti-aging

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca

Copper pca~0.25–0.45%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin

More about Copper pca

Curcuma longa root extract~0.2–0.4%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract

Sodium hydroxide~0.25–0.45%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

T-butyl alcohol~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Used to dissolve other ingredients and to improve smell of products. It could be irritating

More about T-butyl alcohol

Sodium benzoate~0.25–0.4%

Formula

Irritation risk: Low

A preservative

More about Sodium benzoate

Tocopherol~0.25–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Sorbic acid~0.2–0.35%

Irritant · medium

Irritation risk: Medium

A preservative

More about Sorbic acid

Aspergillus/molasses ferment filtrate~0.2–0.35%

Formula

Irritation risk: Low

More about Aspergillus/molasses ferment filtrate

Leuconostoc/radish root ferment filtrate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

A preservative that comes from radishes fermented by a bacteria. New research suggests that the preservation properties in the ingredient come from an ammonium salt that is not present naturally in radish root but used in its cultivation. Is problematic because the exact amount of the preservative agents is difficult to determine

More about Leuconostoc/radish root ferment filtrate

Jasminum officinale flower extract~0.15–0.25%

Irritant · high

Irritation risk: High

Fragrance. Can be irritating

More about Jasminum officinale flower extract

Limonene~0.15–0.3%

Irritant · high

Irritation risk: High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene

Linalool~0.15–0.25%

Irritant · high

Irritation risk: High

A fragrance. Can be irritating

More about Linalool

Phenoxyethanol~0.15–0.25%

Formula

Irritation risk: Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol

Citric acid~0.05–0.15%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Ingredient list view

Water, Aloe barbadensis leaf juice, Propanediol, Glycerin, Isopentyldiol, Polyglyceryl-4 caprate, Arginine, Dicaprylyl ether, Gluconolactone, Caprylic/capric triglyceride, Caprylyl glycol, Allantoin, Sh-oligopeptide-1, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Pentylene glycol, Polyacrylate crosspolymer-6, Isomalt, Panthenol, Glucosyl hesperidin, Citrus nobilis peel oil, Sodium gluconate, Sodium acrylates copolymer, Glycyrrhiza glabra rhizome/root extract, Menthoxypropanediol, Lactic acid, Betaine, Lecithin, Boswellia carterii oil, Hippophae rhamnoides fruit oil, Lactobacillus/salix purpurea bark ferment extract, Ganoderma lucidum extract, Tremella fuciformis sporocarp extract, Sodium hyaluronate, Zinc hydrolyzed hyaluronate, Serenoa serrulata fruit extract, Epilobium angustifolium flower/leaf/stem extract, Argania spinosa callus culture extract, Potassium sorbate, Tasmannia lanceolata fruit/leaf extract, Arnica montana flower extract, Camellia sinensis leaf extract, Phospholipids, Magnesium pca, Zinc pca, Copper pca, Curcuma longa root extract, Sodium hydroxide, T-butyl alcohol, Sodium benzoate, Tocopherol, Sorbic acid, Aspergillus/molasses ferment filtrate, Leuconostoc/radish root ferment filtrate, Jasminum officinale flower extract, Limonene, Linalool, Phenoxyethanol, Citric acid

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ClearStem

$68.00

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	CLEARSTEM SkincareCELLRENEW - Collagen Stem Cell SerumYOUR PRODUCT	Angela CagliaCell Forté Serum	Cos De BAHAES EGF Peptide Serum	simplyOReal Effect EGF Ampoule
Match	—	51%	51%	51%
Price	$68.00	$325.00+$257.00	$13.80−$54.20	$18.64−$49.36
Shared key ingredients	—	8 of 18	7 of 18	6 of 18
Key difference	—	Sh-Polypeptide-9	Madecassoside	Niacinamide
Irritancy	High	Medium	Low	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

More alternatives: Kate Somerville KX Concentrate Bio-Mimicking Peptides Serum OSKIA Deal Two: OSKIA Isotonic Hydra-Serum

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Product summary

"CLEARSTEM - CELLRENEW - Collagen Stem Cell Serum" is effective for: Moisturizing

This product could be helpful for: Anti-aging, but its actives are not the most effective or are not well-studied.

Ingredient callouts

This product contains acids (gluconolactone 0.95% - 1.20% and lactic acid 0.20% - 0.35%). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). PHAs (gluconolactone) especially are great for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
Peptides (sh-oligopeptide-1 0.40% - 0.60%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
Humectants (copper pca 0.25% - 0.45%, zinc pca 0.20% - 0.40%, magnesium pca 0.25% - 0.40%, sodium hyaluronate 0.25% - 0.45%, tremella fuciformis sporocarp extract 0.25% - 0.45%, betaine 0.20% - 0.35%, panthenol 0.30% - 0.50%, isomalt 0.30% - 0.55%, arginine 1.50% - 1.80% and glycerin 3.00% - 3.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.