Cetaphil

Cetaphil PRO Moisturising Night Cream

Name: Cetaphil - PRO Moisturising Night Cream
Brand: Cetaphil

Efficacy100/100IrritancyLow

See all ingredients In 7 routines

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Works for

1 of 1 advertised claim delivered

Moisturizing

19 ingredients credited for this claim

Strong support

What the product description says

“PRO Moisturising Night Cream”

From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, panthenol

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.3–0.5%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.35–0.65%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~7–8.5%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.35–0.65%

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~1.5–1.8%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.1%

Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~2–2.5%

Butyrospermum parkii butterKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~1.2–1.5%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~1–1.2%

Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~0.25–0.5%

Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~1.6–2%

Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~2.4–2.9%

Glyceryl stearate citrate· EmollientEffect: LowHelps oil and water mix together while softening the upper layer of the skin~0.25–0.45%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.6–0.9%

Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.15–0.3%

Behenyl alcohol· Emollient, OcclusiveEffect: LowNon-drying alcohol that helps water and oil mix together. Also serves as an emollient~0.7–1.1%

Dipotassium glycyrrhizateUnder-dosedEffect: HighA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.35–0.65%

AllantoinUnder-dosedEffect: HighHelps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated~0.35–0.6%

NiacinamideUnder-dosedEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.15–0.25%

Can it cause trouble?

Irritancy

11 flagged ingredients

Low risk

We flag 11 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.

IngredientFunctionIrritationEst. amount

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~7–8.5%est.

Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~2.4–2.9%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.45–0.7%est.

CaffeineMight be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyesMedium~0.25–0.45%est.

Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.

Ceteareth-20Helps oil and water mix together. Has some emollient propertiesMedium~0.3–0.55%est.

Disodium ethylene dicocamide peg-15 disulfateHelps oil and water mix togetherMedium~0.25–0.5%est.

Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.15–0.3%est.

Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.1–0.2%est.

Disodium edtaStabilizes the product formulationMedium~0.1–0.15%est.

BhtA preservativeMedium~0.05%est.

Comedogenic

3 ingredients rated 2 or more on the 0–5 pore-clogging scale

3 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~1.2–1.5%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~1–1.2%est.

Ceteareth-20Helps oil and water mix together. Has some emollient properties2/5~0.3–0.55%est.

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Cheaper Alternatives

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Boots Skin Clear Lotion with niacinamide

80% match

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76% match

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Caprylic/capric triglyceride~7–8.5%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Glycerin~4.2–5.1%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Propanediol~3.1–3.8%

Formula

Irritation risk: Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol

Pentylene glycol~2.4–2.9%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol

Helianthus annuus seed oil~2–2.5%

Key active

Irritation risk: Low

Works for

Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil

Sorbitol~1.6–2%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol

Dimethicone~1.5–1.8%

Key active

Irritation risk: Low

Works for

MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone

Butyrospermum parkii butter~1.2–1.5%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-agingAnti-oxidation

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter

Cetearyl alcohol~1–1.2%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Behenyl alcohol~0.7–1.1%

Formula

Irritation risk: Low

Works for

Moisturizing

Non-drying alcohol that helps water and oil mix together. Also serves as an emollient

More about Behenyl alcohol

Glyceryl stearate~0.6–0.9%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Sodium hydroxide~0.5–0.75%

Formula

Irritation risk: Low

Used to adjust the product's pH

More about Sodium hydroxide

Tocopheryl acetate~0.45–0.7%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Allantoin~0.35–0.6%

Under-dosed

Irritation risk: Low

Works for

Anti-inflammatoryMoisturizingAnti-blemishReduces rednessReduces irritationExfoliation

Helps calm down inflammation in skin and can help reduce itching. Helps to repair the skin barrier and keep skin hydrated

More about Allantoin

Dipotassium glycyrrhizate~0.35–0.65%

Under-dosed

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate

Sodium hyaluronate~0.35–0.65%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Ceramide np~0.35–0.65%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-inflammatoryReduces irritation

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Panthenol~0.3–0.5%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Caffeine~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Works for

De-puffingAnti-oxidation

Might be helpful in neutralizing free radicals. Can have a dehydration effect that might somewhat decrease the look of puffy eyes

More about Caffeine

Citric acid~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid

Cetyl alcohol~0.25–0.5%

Key active

Irritation risk: Low

Works for

CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol

Ceteareth-20~0.3–0.55%

Comedogenic 2/5Irritant · medium

Irritation risk: Medium
Comedogenicity: 2/5

Works for

Cleansing

Helps oil and water mix together. Has some emollient properties

More about Ceteareth-20

Glyceryl stearate citrate~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together while softening the upper layer of the skin

More about Glyceryl stearate citrate

Disodium ethylene dicocamide peg-15 disulfate~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Disodium ethylene dicocamide peg-15 disulfate

Niacinamide~0.15–0.25%

Under-dosed

Irritation risk: Low

Works for

MoisturizingEvens skin toneAnti-blemishAnti-agingReduces irritationAntibacterialReduces rednessAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Caprylyl glycol~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol

Acrylates/c10-30 alkyl acrylate crosspolymer~0.1–0.2%

Irritant · medium

Irritation risk: Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer

Disodium edta~0.1–0.15%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Xanthan gum~0.05–0.15%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Bht~0.05%

Irritant · medium

Irritation risk: Medium

A preservative

More about Bht

Ingredient list view

Water, Caprylic/capric triglyceride, Glycerin, Propanediol, Pentylene glycol, Helianthus annuus seed oil, Sorbitol, Dimethicone, Butyrospermum parkii butter, Cetearyl alcohol, Behenyl alcohol, Glyceryl stearate, Sodium hydroxide, Tocopheryl acetate, Allantoin, Dipotassium glycyrrhizate, Sodium hyaluronate, Ceramide np, Panthenol, Caffeine, Citric acid, Cetyl alcohol, Ceteareth-20, Glyceryl stearate citrate, Disodium ethylene dicocamide peg-15 disulfate, Niacinamide, Caprylyl glycol, Acrylates/c10-30 alkyl acrylate crosspolymer, Disodium edta, Xanthan gum, Bht

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	CetaphilPRO Moisturising Night CreamYOUR PRODUCT	Dr Sam'sFlawless Moisturiser	CeraVeFacial Moisturising Lotion	BootsSkin Clear Lotion with niacinamide
Match	—	82%	81%	80%
Price	$13.09	$33.05+$19.96	$14.28+$1.19	$5.29−$7.80
Shared key ingredients	—	7 of 12	6 of 12	7 of 12
Key difference	—	Anhydroxylitol	Ceramide Eop	Mineral Oil
Irritancy	Low	Low	Low	Low
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"Cetaphil - PRO Moisturising Night Cream" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. Cetaphil - PRO Moisturising Night Cream ticks this box. Humectants in this product (panthenol, glycerin, sodium hyaluronate, caprylyl glycol and sorbitol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide np, butyrospermum parkii butter, caprylic/capric triglyceride, dimethicone and helianthus annuus seed oil) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

Another benefit is that this moisturizer contain ceramides (ceramide np 0.35% - 0.65%). Ceramides are an important part of our natural skin barrier. The ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.

Irritation risk

This product does not contain known common irritants and is suitable for sensitive skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 11.24£ up to 16.42£ in the United Kingdom and for 26.30CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Effect of Olive and Sunflower Seed Oil on the Adult Skin Barrier: Implications for Neonatal Skin Careonlinelibrary.wiley.com
3
Topically Applied Sunflower Seed Oil Prevents Invasive Bacterial Infections in Preterm Infants in Egyptjournals.lww.com
4
Effect of topically applied lipids on surfactant-irritated skinonlinelibrary.wiley.com
5
Impact of topical oils on the skin barrier: possible implications for neonatal health in developing countriesonlinelibrary.wiley.com
6
Dimethicone as a protective ingredient in topical medicationsjaad.org
7
Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
8
Profile of wound healing process induced by allantoinscielo.br
9
Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent modelresearchgate.net
10
Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.ncbi.nlm.nih.gov
11
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
12
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
13
Skin hydration is significantly increased by a cream formulated to mimic the skin’s own natural moisturizing systemsncbi.nlm.nih.gov
14
Topically Applied Ceramides Interact with the Stratum Corneum Lipid Matrix in Compromised Ex Vivo Skinncbi.nlm.nih.gov
15
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
16
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
17
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
18
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov

CetaphilPRO Moisturising Night Cream

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