Dupes & alternatives for Cetaphil-Optimal Hydration 48 Hour Activation Serum

Optimal Hydration 48 Hour Activation Serum
Cetaphil

Optimal Hydration 48 Hour Activation Serum

Low irritancy Score: 75/100
20 alternatives found · Best match: 50% (Medium)
Serum Oil-Cocktail Night Repair- 1 pcs
50%
Medium match
Medium irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +3 more

Key differences

OLIGOPEPTIDE-5OLIGOPEPTIDE-13-O-ETHYL ASCORBIC ACID +9 more
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Hydrating Complex
49%
Medium match
$79.20
Low irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +2 more

Key differences

CALCIUM PANTOTHENATEPANTETHINESODIUM HYALURONATE +2 more
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Similarity breakdown
Overall formula49%
Hero ingredients200%
Active ingredients94%
All ingredients28%
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The Oasis - Barrier Booster
49%
Medium match
$68.00
Low irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +1 more

Key differences

MADECASSOSIDEBIOSACCHARIDE GUM-1CENTELLA ASIATICA EXTRACT +6 more
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Similarity breakdown
Overall formula49%
Hero ingredients200%
Active ingredients75%
All ingredients24%
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Hydrating Serum
48%
Medium match
$8.50
Medium irritancy

Why it matches

ANHYDROXYLITOLGLYCERINHELIANTHUS ANNUUS SEED OIL +1 more

Key differences

LACTIC ACIDCAPRYLIC/CAPRIC TRIGLYCERIDEGLYCINE SOJA OIL +4 more
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Inhibit High Definition Serum
47%
Medium match
$360.00
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLHYDROLYZED HYALURONIC ACID +3 more

Key differences

COPPER HEPTAPEPTIDE-14 PANTOTHENATENIACINAMIDEHEPTAPEPTIDE-15 PALMITATE +19 more
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Circular Hydration Serum with Hyaluronic Acid
$28.00
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +2 more

Key differences

LACTIC ACIDAVENA SATIVA KERNEL EXTRACTGLUTAMIC ACID +16 more
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Antioxidant Dew Hydrating Serum
46%
Medium match
$90.00
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +2 more

Key differences

FERULIC ACIDMANNITOLROSMARINUS OFFICINALIS LEAF EXTRACT +6 more
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Real Complexion Pink Capsule Serum
46%
Medium match
$28.33
Medium irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLHELIANTHUS ANNUUS SEED OIL +2 more

Key differences

ASCORBIC ACID POLYPEPTIDELACTOBIONIC ACIDCERAMIDE NP +10 more
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Ultimate Hydrate Hyaluronic Serum
46%
Medium match
$24.00
Medium irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +2 more

Key differences

MADECASSOSIDENIACINAMIDEADENOSINE +16 more
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Nighttime Anti-Aging Therapy with Vitamin C & Retinol
45%
Medium match
$50.00
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +1 more

Key differences

RETINOL3-O-ETHYL ASCORBIC ACIDDIMETHICONOL +8 more
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& Lipopeptide Serum
Triple Hyaluronic Acid
& Lipopeptide Serum
45%
Medium match
$60.00
Low irritancy

Why it matches

ANHYDROXYLITOLGLYCERINHYDROLYZED HYALURONIC ACID +1 more

Key differences

ACETYL DIPEPTIDE-1 CETYL ESTERCHONDRUS CRISPUS EXTRACTHYALURONIC ACID +3 more
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Dermask Solution 1pc
44%
Medium match
$6.90
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +3 more

Key differences

SALICYLIC ACIDNIACINAMIDESODIUM ASCORBYL PHOSPHATE +30 more
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Serum Mini Stocking Stuffer
44%
Medium match
High irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +3 more

Key differences

ASCORBIC ACIDRETINOLCHONDRUS CRISPUS EXTRACT +17 more
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Calming Serum
Dr. Barbara Sturm
Calming Serum
43%
Medium match
$65.00
Low irritancy

Why it matches

PANTHENOLGLYCERINPANTOLACTONE

Key differences

DIMETHICONEECHIUM PLANTAGINEUM SEED OILHELIANTHUS ANNUUS SEED OIL UNSAPONIFIABLES +2 more
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Common ingredients (3)
Similarity breakdown
Overall formula43%
Hero ingredients100%
Active ingredients56%
All ingredients34%
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Doctor Babor Repair Cellular: Ultimate Calming Serum
$61.85
Low irritancy

Why it matches

PANTHENOLPANTOLACTONEGLYCERIN

Key differences

DIMETHICONEECHIUM PLANTAGINEUM SEED OILBIOSACCHARIDE GUM-1 +1 more
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Common ingredients (3)
Similarity breakdown
Overall formula43%
Hero ingredients100%
Active ingredients56%
All ingredients34%
View full product details
Healthy, Glowing Skin Duo
42%
Medium match
$47.98
Medium irritancy

Why it matches

ANHYDROXYLITOLPANTHENOLGLYCERIN +3 more

Key differences

DIMETHICONOLSODIUM HYALURONATESODIUM HYALURONATE +5 more
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Face & Neck Regenerative Serum
42%
Medium match
$125.00
Low irritancy

Why it matches

ANHYDROXYLITOLGLYCERINXYLITYLGLUCOSIDE

Key differences

PALMITOYL TRIPEPTIDE-1PALMITOYL TETRAPEPTIDE-7HYDROLYZED SODIUM HYALURONATE +4 more
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Similarity breakdown
Overall formula42%
Hero ingredients100%
Active ingredients56%
All ingredients28%
View full product details
Hyaluronic acid + ceramide booster
42%
Medium match
$2500.00
Low irritancy

Why it matches

PANTHENOLGLYCERINHYDROLYZED HYALURONIC ACID

Key differences

CERAMIDE NPPHYTOSPHINGOSINECERAMIDE AP +9 more
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About Similarity Scores

Our similarity score compares product formulas based on shared active ingredients, hero ingredients, and overall formula composition. A higher score means a more similar formula.

70%+ - High match
40-69% - Medium match
<40% - Low match

Note: Similarity is based on WIMJ's formula analysis (actives + overall formula similarity). Ingredient concentrations are estimated; products aren't lab-tested. A similar formula doesn't guarantee the same texture or feel.