Cetaphil Hydrating Night Cream

Cetaphil Hydrating Night Cream

Efficacy100/100IrritancyLow
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Works for

1 of 1 advertised claim delivered

Moisturizing
14 ingredients credited for this claim
Strong support
What the product description says
“This nourishing yet fast absorbing cream with Hyaluronic Acid instantly rehydrates and gently nourishes skin overnight, so the skin feels soft and smooth.”
Source: Supderdrug

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, pantolactone.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, dimethiconol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol, petrolatum

PetrolatumHero· Emollient, OcclusiveEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~3.7–5.6%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.35–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~3.9–5.9%
Helianthus annuus seed oilKey active· Emollient, OcclusiveEffect: HighA great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function~1.3–2%
NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.5–1.2%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.85–1.25%
PantolactoneKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~0.3–0.7%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.1–3.1%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~0.45–1.05%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.4–2.1%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.15–0.5%
Dicaprylyl ether· EmollientEffect: LowHelps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients~2.7–4.1%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.7–2.5%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.9%
Anti-aging
Not advertised by the brand · 3 ingredients credited for this claim
Strong support

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains niacinamide.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.5–1.2%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~0.45–1.05%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.4–0.9%
Evens skin tone
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.5–1.2%
Anti-blemish
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.5–1.2%

Can it cause trouble?

Irritancy
8 flagged ingredients
Low risk
We flag 8 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.15–0.5%est.
Benzyl alcoholA preservative. Can be used to mask unpleasant smell. Can be irritatingHigh~0.05–0.2%est.
Peg-30 stearateHelps oil and water mix togetherMedium~1–1.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.35–0.8%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.15–0.65%est.
BhtA preservativeMedium~0.1–0.45%est.
Disodium edtaStabilizes the product formulationMedium~0.1–0.35%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.05–0.1%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
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Ingredients

Filter by role to see what each ingredient is doing.

Water~40–60%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~3.9–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Petrolatum~3.7–5.6%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Dicaprylyl ether~2.7–4.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin while creating a non-greasy feel on the skin. Helps to dissolve other ingredients

More about Dicaprylyl ether
Dimethicone~2.1–3.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glyceryl stearate~1.7–2.5%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cetyl alcohol~1.4–2.1%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Helianthus annuus seed oil~1.3–2%
Key active
Irritation risk
Low
Works for
Moisturizing

A great emollient due to its high linoleic acid content. One of the most effective plant oils in helping skin hydration and repairing skin barrier function

More about Helianthus annuus seed oil
Peg-30 stearate~1–1.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Peg-30 stearate
Panthenol~0.85–1.25%
Hero · Moisturizing
Irritation risk
Low
Works for
Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Niacinamide~0.5–1.2%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Anti-agingEvens skin toneAnti-blemishMoisturizingReduces irritationReduces rednessAnti-inflammatoryAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Prunus amygdalus dulcis oil~0.45–1.05%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Tocopherol~0.4–0.9%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-agingAnti-inflammatoryMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Tocopheryl acetate~0.35–0.8%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Pantolactone~0.3–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Pantolactone
Dimethiconol~0.35–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Acrylates/c10-30 alkyl acrylate crosspolymer~0.15–0.65%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Carbomer~0.15–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Propylene glycol~0.15–0.5%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Bht~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Bht
Disodium edta~0.1–0.35%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Benzyl alcohol~0.05–0.2%
Irritant · high
Irritation risk
High

A preservative. Can be used to mask unpleasant smell. Can be irritating

More about Benzyl alcohol
Phenoxyethanol~0.1–0.3%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Sodium hydroxide~0.05–0.25%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Citric acid~0.05–0.1%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Glycerin, Petrolatum, Dicaprylyl ether, Dimethicone, Glyceryl stearate, Cetyl alcohol, Helianthus annuus seed oil, Peg-30 stearate, Panthenol, Niacinamide, Prunus amygdalus dulcis oil, Tocopherol, Tocopheryl acetate, Pantolactone, Dimethiconol, Acrylates/c10-30 alkyl acrylate crosspolymer, Carbomer, Propylene glycol, Bht, Disodium edta, Benzyl alcohol, Phenoxyethanol, Sodium hydroxide, Citric acid

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Amazon USPrice as of 10/20/2026 07:51 GMT
$18.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CetaphilHydrating Night CreamYOUR PRODUCTBootsSkin Clear Lotion with niacinamideRilastilAcnestil Attiva CreamOlayCollagen Peptide Day Cream
Match—82%82%82%
Price$1.32$5.29+$3.97$24.44+$23.12$22.12+$20.80
Shared key ingredients—5 of 96 of 95 of 9
Key difference—Mineral OilPotassium Azeloyl DiglycinatePalmitoyl Pentapeptide-4
Irritancy Low Low Low Low
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 18 studies and safety reviews.

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