Cetaphil Healthy Renew Night Cream
Works for
2 of 3 advertised claims delivered
Anti-agingAdenosine, Butyrospermum parkii butter + 1 moreStrong evidence
“Visibly reduces the look of fine lines and wrinkles in 2 weeks”
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
MoisturizingPanthenol, Beeswax + 16 moreStrong evidence
“Hydrates for 48 hours and smooths the appearance of fine lines and wrinkles”
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, caprylyl glycol.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, cetearyl alcohol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: panthenol
Evens skin toneNiacinamideWeak evidence
“This night cream also contains vitamins B3 (niacinamide) and B5 (panthenol) to help hydrate, soothe and repair the skin barrier, plus botanical extracts (rice lees and edelweiss) to target visible dullness and uneven skin tone.”
Effective ingredients missing or their concentration is too low
Can it cause trouble?
Irritancy1 strong irritant: Thymus vulgaris extractMedium risk
Comedogenic3 ingredients rated 2 or more on the 0–5 pore-clogging scale3 flagged
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Ingredients
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Water~45–55%
Propanediol~4.8–5.9%
- Irritation risk
- Low
Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin
More about PropanediolCetyl ethylhexanoate~4.1–5%
- Irritation risk
- Medium
An emollient that helps soften the skin and creates a thicker product texture
More about Cetyl ethylhexanoateDibutyl adipate~3.1–3.8%
- Irritation risk
- Low
Helps soften the upper layer of the skin and create a nice product consistency
More about Dibutyl adipateHydrogenated polydecene~2.3–2.8%
- Irritation risk
- Low
Helps to soften the upper layer of the skin and create a nice product texture
More about Hydrogenated polydeceneCoco-caprylate/caprate~2–2.4%
- Irritation risk
- Low
Helps to soften the upper layer of the skin without creating a greasy texture
More about Coco-caprylate/capratePanthenol~1.6–1.9%
- Irritation risk
- Low
Helps attract water to the upper layer of the skin and can help improve skin barrier function
More about PanthenolPolyglyceryl-6 stearate~1.5–1.8%
- Irritation risk
- Low
Helps soften the upper layer of the skin
More about Polyglyceryl-6 stearateGlycerin~1.2–1.5%
- Irritation risk
- Low
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
More about GlycerinBeeswax~1–1.3%
- Irritation risk
- Low
Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen
More about BeeswaxCetearyl alcohol~0.8–1.2%
- Irritation risk
- Low
- Comedogenicity
- 2/5
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
More about Cetearyl alcoholNiacinamide~0.6–0.9%
- Irritation risk
- Low
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
More about NiacinamidePalmitic acid~0.6–0.9%
- Irritation risk
- Low
An emollient that is naturally present in skin and helps soften it
More about Palmitic acidStearic acid~0.6–0.95%
- Irritation risk
- Low
Helps oil and water mix together and works as an emollient
More about Stearic acidButyrospermum parkii butter~0.5–0.8%
- Irritation risk
- Low
- Comedogenicity
- 3/5
A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals
More about Butyrospermum parkii butterGlyceryl stearate~0.5–0.8%
- Irritation risk
- Low
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
More about Glyceryl stearateSodium acrylate/sodium acryloyldimethyl taurate copolymer~0.45–0.7%
- Irritation risk
- Low
Used to create a thicker product consistency
More about Sodium acrylate/sodium acryloyldimethyl taurate copolymerCaprylyl glycol~0.45–0.65%
- Irritation risk
- Medium
Helps preserve products and creates a nice product texture
More about Caprylyl glycolIsohexadecane~0.5–0.75%
- Irritation risk
- Low
Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent
More about IsohexadecaneLeontopodium alpinum extract~0.3–0.6%
- Irritation risk
- Low
Polyglyceryl-6 behenate~0.3–0.6%
Ethylhexylglycerin~0.3–0.55%
Carbomer~0.25–0.5%
- Irritation risk
- Low
Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations
More about CarbomerTromethamine~0.25–0.5%
Hydrogenated olive oil unsaponifiables~0.3–0.55%
- Irritation risk
- Low
Help soften the upper layer of the skin
More about Hydrogenated olive oil unsaponifiablesOryza sativa lees extract~0.25–0.45%
- Irritation risk
- Low
Tocopheryl acetate~0.25–0.5%
- Irritation risk
- Medium
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
More about Tocopheryl acetatePolysorbate 80~0.25–0.5%
1,2-hexanediol~0.2–0.4%
Adenosine~0.2–0.4%
- Irritation risk
- Low
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
More about AdenosineSorbitan oleate~0.2–0.35%
- Irritation risk
- Medium
- Comedogenicity
- 2/5
Helps oil and water mix together
More about Sorbitan oleateCitric acid~0.15–0.3%
- Irritation risk
- Medium
Can work as an exfoliant but is typically used to adjust the product pH
More about Citric acidSodium benzoate~0.1–0.2%
Potassium sorbate~0.15–0.25%
Hydrolyzed soy flour~0.1–0.2%
- Irritation risk
- Low
Buddleja davidii extract~0.05–0.15%
- Irritation risk
- Low
Thymus vulgaris extract~0.05–0.1%
- Irritation risk
- High
Ingredient list view
Water, Propanediol, Cetyl ethylhexanoate, Dibutyl adipate, Hydrogenated polydecene, Coco-caprylate/caprate, Panthenol, Polyglyceryl-6 stearate, Glycerin, Beeswax, Cetearyl alcohol, Niacinamide, Palmitic acid, Stearic acid, Butyrospermum parkii butter, Glyceryl stearate, Sodium acrylate/sodium acryloyldimethyl taurate copolymer, Caprylyl glycol, Isohexadecane, Leontopodium alpinum extract, Polyglyceryl-6 behenate, Ethylhexylglycerin, Carbomer, Tromethamine, Hydrogenated olive oil unsaponifiables, Oryza sativa lees extract, Tocopheryl acetate, Polysorbate 80, 1,2-hexanediol, Adenosine, Sorbitan oleate, Citric acid, Sodium benzoate, Potassium sorbate, Hydrolyzed soy flour, Buddleja davidii extract, Thymus vulgaris extract
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Worth comparing, line by line.
Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.
| CetaphilHealthy Renew Night CreamYOUR PRODUCT | It CosmeticsConfidence in a Cream Barrier Boost Skin Barrier Repair Moisturizer | iUNIKBeta Glucan 3X Barrier Cream 50ml | Serendi BeautyLa-bloom Vital Repair Cream | |
|---|---|---|---|---|
| Match | — | 92% | 92% | 90% |
| Price | $18.59 | $39.20+$20.61 | $18.23 | $74.42+$55.83 |
| Shared key ingredients | — | 5 of 6 | 5 of 6 | 5 of 6 |
| Key difference | — | Acetyl Dipeptide-1 Cetyl Ester | Ceramide Np | Oligopeptide-1 |
| Irritancy | Medium | Low | Low | Medium |
| Drying alcohol | — | — | — | — |
| View product | Shop | Shop | Shop |
Product summary
Based on the ingredients included, "Cetaphil - Healthy Renew Night Cream" works well for moisturizing the skin. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Panthenol, glycerin and caprylyl glycol in this product (humectants) attract water molecules to the upper layer of the skin (the water comes from the outside air or from the deeper layers of the skin if the air is dry). Beeswax, cetearyl alcohol, coco-caprylate/caprate, hydrogenated olive oil unsaponifiables and polyglyceryl-6 stearate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- Adenosine 0.20% - 0.40%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
- An effective concentration of Panthenol (pro-vitamin B5) - about 1.60% - 1.90%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
Irritation risk
There are some common irritants in this product, including ingredients that do not have benefits for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Price
The product retails for 19.99$ in the United States.
For a detailed price comparison: click here.
Sources cited in this review
Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.
- 1Safety Assessment of Polyene Group as Used in Cosmeticscir-safety.org
- 2Safety Assessment of Alkyl Esters as Used in Cosmeticscir-safety.org
- 3Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
- 4
- 5
- 6
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