Cetaphil Daily Defence Moisturiser SPF 50

Cetaphil Daily Defence Moisturiser SPF 50

SPF 50Efficacy90/100IrritancyLow·8 UV filters
Edit

Works for

1 of 2 advertised claims delivered

Sun protection
SPF 50 · 8 UV filters
Broad spectrum
SPF 50Broad spectrumMineral + chemical filters

This product offers a good level of protection against both UVB and UVA rays.

This sunscreen uses organic (so-called "chemical") sunscreen filters. Organic, or "chemical" filters usually provide reliable sun protection and rarely leave a white cast. Sunscreens with organic filters can sting eyes.

This product can be considered "reef safe" because it does not contain the UV filters (oxybenzone and octinoxate) that can be harmful to coral reefs when present in the water in high concentrations.

UV spectrum
UVB290–320 nmUVA II320–340 nmUVA I340–400 nm
Octisalate
Octocrylene
Uvinul T
Titanium Dioxide
Mexoryl Xl
Tinosorb S
Avobenzone
Terephthalylidene Dicamphor Sulfonic Acid
FilterCoverageWhat it doesEst. amount
OctisalateEthylhexyl SalicylateUVBOctisalate. A UV filter. It offers some protection against the sun rays that cause sunburn (UVB), but does not protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen~4–4.9%
OctocryleneUVB Photo-stable A weak sunscreen that protects against the sun rays that cause sunburn (UVB) and is somewhat effective against the UVA rays. It is quite stable and can help stabilize other, more vulnerable, sunscreen ingredients like Avobenzone. It is an organic, or so called "chemical" sunscreen~1.8–2.2%
Uvinul TEthylhexyl TriazoneUVB Photo-stable Uvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yet~0.55–0.85%
Titanium Dioxide Mineral UVBUVA2 Photo-stable Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin~3.5–4.3%
Mexoryl XlDrometrizole TrisiloxaneUVBUVA2 Photo-stable Mexoryl XL. A UV filter. Effective in the UVB and UVA range. It is stable. Unfortunately, not approved in the US yet~0.6–0.9%
Tinosorb SBis-ethylhexyloxyphenol Methoxyphenyl TriazineUVBUVA Photo-stable Tinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Unfortunately, not approved by FDA (US) yet.~2.1–2.5%
AvobenzoneButyl MethoxydibenzoylmethaneUVA1Avobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.~2.7–3.3%
Terephthalylidene Dicamphor Sulfonic AcidUVA1 Photo-stable Ecamsule, Mexoryl SX. A UV filter. Is effective mostly against the UVA rays. It is legally marketed in the US with the FDA approval since 2006, even though the ingredient is not on the official FDA list of the approved sunscreen active ingredients. It is photostable~0.35–0.65%
~ marks concentrations estimated from label position and typical use levels
Reef-safe
No oxybenzone or octinoxate — the two filters banned in Hawaii, Florida Keys and Aruba.
Anti-blemish
No ingredient credited for this claim
No support
What the product description says
“Does not block pores.”
Source: Feelunique

Effective ingredients missing or their concentration is too low.

Evens skin tone
Not advertised by the brand · No ingredient credited for this claim
Strong support

This product offers broad spectrum sun protection. It means that it can prevent hyperpigmentation and help keep the skin tone even (sun damage is the main factor causing age spots, darkening of post-acne marks and other discolorations).

Anti-aging
Not advertised by the brand · 1 ingredient credited for this claim
Strong support

This product can help prevent early signs of skin aging because it offers a good level of broad spectrum sun protection. Sun damage is the main cause of premature skin aging, and protecting your skin from the sun is the best anti-aging strategy.

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%
Moisturizing
Not advertised by the brand · 9 ingredients credited for this claim
Good support

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, c12-15 alkyl benzoate.

DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.7–1.05%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.8–5.9%
C12-15 alkyl benzoateKey active· EmollientEffect: MediumEnhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth~6.6–8.1%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~1.1–1.4%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.4–0.65%
Stearic acid· EmollientEffect: LowHelps oil and water mix together and works as an emollient~1–1.2%
PetrolatumUnder-dosedEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.55–0.8%
Myristyl myristateUnder-dosedEffect: HighAn emollient. Is not recommended for acne-prone skin as it can be comedogenic~0.35–0.65%
TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.35%

Can it cause trouble?

Irritancy
12 flagged ingredients
Low risk
We flag 12 ingredients with irritancy potential; the product's overall irritancy is low. The table lists each ingredient's own rating.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~1.8–2.2%est.
Butyl methoxydibenzoylmethaneAvobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.Medium~2.7–3.3%est.
Bis-ethylhexyloxyphenol methoxyphenyl triazineTinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Unfortunately, not approved by FDA (US) yet.Medium~2.1–2.5%est.
OctocryleneA weak sunscreen that protects against the sun rays that cause sunburn (UVB) and is somewhat effective against the UVA rays. It is quite stable and can help stabilize other, more vulnerable, sunscreen ingredients like Avobenzone. It is an organic, or so called "chemical" sunscreenMedium~1.8–2.2%est.
Disodium edtaStabilizes the product formulationMedium~0.45–0.7%est.
Drometrizole trisiloxaneMexoryl XL. A UV filter. Effective in the UVB and UVA range. It is stable. Unfortunately, not approved in the US yetMedium~0.6–0.9%est.
Ethylhexyl triazoneUvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yetMedium~0.55–0.85%est.
Hydroxypropyl methylcelluloseUsed to create a thicker product consistency and stabilize the formulationMedium~0.3–0.6%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenicMedium~0.35–0.65%est.
Potassium cetyl phosphateHelps oil and water mix togetherMedium~0.3–0.6%est.
Terephthalylidene dicamphor sulfonic acidEcamsule, Mexoryl SX. A UV filter. Is effective mostly against the UVA rays. It is legally marketed in the US with the FDA approval since 2006, even though the ingredient is not on the official FDA list of the approved sunscreen active ingredients. It is photostableMedium~0.35–0.65%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.15–0.3%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenic3/5~0.35–0.65%est.
Hydrogenated soybean oil—2/5~0.35–0.65%est.
Edit
Cheaper Alternatives
Similar formulations, better price
No cheaper similar product found.

User reviews

Would you recommend?
0%·yes

0 of 3 community members would buy it again.

0% would100% wouldn't
Write a review · ~30s
What reviewers noticed
Marker shows the average response

Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
C12-15 alkyl benzoate~6.6–8.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Enhances the product texture and makes it more spreadable. Helps reduce water loss from the outer layer of skin. Extands the shelf life by preventing bacteria growth

More about C12-15 alkyl benzoate
Glycerin~4.8–5.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Ethylhexyl salicylate~4–4.9%
UV filter
Irritation risk
Low
Works for
Sun protection

Octisalate. A UV filter. It offers some protection against the sun rays that cause sunburn (UVB), but does not protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen

More about Ethylhexyl salicylate
Titanium dioxide~3.5–4.3%
UV filterKey active
Irritation risk
Low
Works for
Sun protection

Works as a UV filter when used in high concentrations. It is photostable and is effective mostly against the UVB light, with some protection in the UVA range. In small concentrations, used for its ability to improve the color of cosmetic products. Is usually well tolerated by the skin

More about Titanium dioxide
Butyl methoxydibenzoylmethane~2.7–3.3%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

Avobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.

More about Butyl methoxydibenzoylmethane
Propylene glycol~1.8–2.2%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Bis-ethylhexyloxyphenol methoxyphenyl triazine~2.1–2.5%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

Tinosorb S. One of the most effective broad spectrum sunscreen ingredients. Protects from both UVA and UVB rays. It is photostable. Unfortunately, not approved by FDA (US) yet.

More about Bis-ethylhexyloxyphenol methoxyphenyl triazine
Octocrylene~1.8–2.2%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

A weak sunscreen that protects against the sun rays that cause sunburn (UVB) and is somewhat effective against the UVA rays. It is quite stable and can help stabilize other, more vulnerable, sunscreen ingredients like Avobenzone. It is an organic, or so called "chemical" sunscreen

More about Octocrylene
Cyclopentasiloxane~1.1–1.4%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Stearic acid~1–1.2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid
Dimethicone~0.7–1.05%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Methyl methacrylate crosspolymer~0.6–0.9%
Formula
Irritation risk
Low
Works for
Mattifying

Helps thicken the product consistency

More about Methyl methacrylate crosspolymer
Nylon-12~0.65–1%
Formula
Irritation risk
Low

Used to create a nice product consistency

More about Nylon-12
Petrolatum~0.55–0.8%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Aluminum hydroxide~0.55–0.8%
Formula
Irritation risk
Low

Is used to add opaque (non-transparent) appearance to formulations. Can be used to coat other ingredients for even dispersion. This is a different ingredient compared to the ones used in antipersperants (aluminium chloride and aluminium chlorohydrate)

More about Aluminum hydroxide
Ammonium polyacryloyldimethyl taurate~0.5–0.75%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Ammonium polyacryloyldimethyl taurate
Disodium edta~0.45–0.7%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Drometrizole trisiloxane~0.6–0.9%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

Mexoryl XL. A UV filter. Effective in the UVB and UVA range. It is stable. Unfortunately, not approved in the US yet

More about Drometrizole trisiloxane
Ethylhexyl triazone~0.55–0.85%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

Uvinul T. A UV filter. Effective against UVB rays. It is photostable. Can increase water resistance properties of the sunscreen. Unfortunately, not approved by the FDA (US) yet

More about Ethylhexyl triazone
Ethylparaben~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Ethylparaben
Glyceryl stearate~0.4–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Hydrogenated soybean oil~0.35–0.65%
Comedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
More about Hydrogenated soybean oil
Hydroxypropyl methylcellulose~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency and stabilize the formulation

More about Hydroxypropyl methylcellulose
Methylparaben~0.15–0.3%
Formula
Irritation risk
Low

A preservative

More about Methylparaben
Myristyl myristate~0.35–0.65%
Under-dosedComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Is not recommended for acne-prone skin as it can be comedogenic

More about Myristyl myristate
Peg-100 stearate~0.45–0.7%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Phenoxyethanol~0.3–0.6%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Potassium cetyl phosphate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Potassium cetyl phosphate
Propylparaben~0.2–0.4%
Formula
Irritation risk
Low

A preservative

More about Propylparaben
Sodium chloride~0.3–0.5%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Stearyl alcohol~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

An emollient that helps soften the skin

More about Stearyl alcohol
Terephthalylidene dicamphor sulfonic acid~0.35–0.65%
UV filterKey activeIrritant · medium
Irritation risk
Medium
Works for
Sun protection

Ecamsule, Mexoryl SX. A UV filter. Is effective mostly against the UVA rays. It is legally marketed in the US with the FDA approval since 2006, even though the ingredient is not on the official FDA list of the approved sunscreen active ingredients. It is photostable

More about Terephthalylidene dicamphor sulfonic acid
Tocopherol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Anti-oxidationAnti-inflammatoryAnti-agingMoisturizing

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol
Triethanolamine~0.15–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Ingredient list view

Water, C12-15 alkyl benzoate, Glycerin, Ethylhexyl salicylate, Titanium dioxide, Butyl methoxydibenzoylmethane, Propylene glycol, Bis-ethylhexyloxyphenol methoxyphenyl triazine, Octocrylene, Cyclopentasiloxane, Stearic acid, Dimethicone, Methyl methacrylate crosspolymer, Nylon-12, Petrolatum, Aluminum hydroxide, Ammonium polyacryloyldimethyl taurate, Disodium edta, Drometrizole trisiloxane, Ethylhexyl triazone, Ethylparaben, Glyceryl stearate, Hydrogenated soybean oil, Hydroxypropyl methylcellulose, Methylparaben, Myristyl myristate, Peg-100 stearate, Phenoxyethanol, Potassium cetyl phosphate, Propylparaben, Sodium chloride, Stearyl alcohol, Terephthalylidene dicamphor sulfonic acid, Tocopherol, Triethanolamine

Compare prices

Retailers ranked by price — lowest first.

Amazon AustraliaPrice as of 10/14/2026 08:12 GMT
≈ $10.36
Buy
Lookfantastic CA
≈ $13.44
Buy
Lookfantastic
≈ $14.41
Buy
Supderdrug
≈ $17.21
Buy
Boots
≈ $19.21
Buy
Face the future
≈ $19.21
Buy
Amazon UK
Price unavailable
Check

Affiliate links · prices updated regularly · As an Amazon Associate, WIMJ earns from qualifying purchases.

Cheaper alternatives? See how this stacks up against similar formulas.
We compare ingredient profiles across our catalog — pick the closest match for your budget.
Open dupe finder

Product summary

We assess that "Cetaphil - Daily Defence Moisturiser SPF 50" can provide reliable sun protection based on the ingredient list. We love that it can protect from both UVA and UVB rays (not all sunscreens with SPF ratings give UVA protection. UVA rays do not cause sunburn, but still damage our skin and lead to early aging).

Its formula is also hydrating, so you might not need an additional moistruizer during the day. This product prevents early signs of aging by protecting against sun damage (all broad spectrum sunscreens do that).

Sunscreen filters

This sunscreen uses a mixture of both mineral and organic (so-called "chemical") UV filters. Here are the organic filters this product uses: tinosorb s, avobenzone, mexoryl xl, octisalate, uvinul t, octocrylene and terephthalylidene dicamphor sulfonic acid. As for the mineral filters, this sunscreen uses titanium dioxide.

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be low. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

What our users say

Based on 1 review 0% recommend this product
  • As for the white cast, the reviewer reported a noticeable whitish residue.
  • When it comes to using this sunscreen under makeup, the user found that it pills under a foundation.
  • As for using this sunscreen in the eye area, the reviewer reported that it stings eyes.
Our users describe the finish of this sunscreen as matt, They find the product's texture to be heavy - light and In terms of the smell, our users report that light fragrance.

Price

The product retails from 10.88£ up to 14.50£ in the United Kingdom and for 19.10CA$ in Canada.

For a detailed price comparison: click here.

Cetaphil Daily Defence Moisturiser SPF 50
CetaphilDaily Defence Moisturiser SPF 50

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

As an Amazon Associate, WIMJ earns from qualifying purchases.