CELDYQUE PDRN 12% EGF Peptide Serum

CELDYQUE PDRN 12% EGF Peptide Serum

Efficacy100/100IrritancyMedium

Works for

Anti-aging
Niacinamide, Acetyl hexapeptide-8 + 4 more
Works well
What the product description says
“A radiance care serum formulated with 12% PDRN and EGF peptide complex for skin renewal support and promotion of collagen production, while delivering deep hydration for a more youthful complexion.”
Source: Yesstyle

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: acetyl hexapeptide-8, pentapeptide-18.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%
Acetyl hexapeptide-8Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.8%
Pentapeptide-18Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.4–0.65%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.15–0.3%
Moisturizing
Niacinamide, Pentapeptide-18 + 17 more
Works well
What the product description says
“A radiance care serum formulated with 12% PDRN and EGF peptide complex for skin renewal support and promotion of collagen production, while delivering deep hydration for a more youthful complexion.”
Source: Yesstyle

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, hyaluronic acid.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: acetyl hexapeptide-8, ceramide np, niacinamide, panthenol, pentapeptide-18

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%
Pentapeptide-18HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.75%
Acetyl hexapeptide-8Hero· HumectantEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.5–0.8%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.45–0.65%
Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.35–0.65%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~4.1–5%
Isopropyl myristateKey active· EmollientEffect: HighAn emollient that helps soften the skin. Could be comedogenic~3.1–3.8%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~0.95–1.2%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.45–0.65%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.45–0.7%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.4–0.65%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.25–0.5%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.15–0.25%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~4.8–5.9%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.4–1.7%
Cetyl peg/ppg-10/1 dimethiconeEffect: LowA type of silicone that helps water and oil mix together. Can help to soften upper layer of the skin~0.6–0.85%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.3–0.5%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~0.15–0.3%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.15–0.3%
Evens skin tone
Niacinamide, Lactic acid
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%
Lactic acidUnder-dosedAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)~0.15–0.3%
Anti-blemish
Side benefit · Niacinamide
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.6–2%

Can it cause trouble?

Irritancy
8 flagged ingredients
Medium risk
We flagged 8 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~4.8–5.9%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~4.1–5%est.
1,2-hexanediolA preservativeMedium~0.65–0.95%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.3–0.5%est.
Lauryl glucosideHelps oil and water mix togetherMedium~0.3–0.55%est.
Lactic acidAn exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)Medium~0.15–0.3%est.
EthylhexylglycerinA preservativeMedium~0.15–0.25%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.01–0.05%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Isopropyl myristateAn emollient that helps soften the skin. Could be comedogenic3/5~3.1–3.8%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Propylene glycol~4.8–5.9%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Caprylic/capric triglyceride~4.1–5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Isopropyl myristate~3.1–3.8%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin. Could be comedogenic

More about Isopropyl myristate
Polysorbate 80~2.3–2.8%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Sodium dna~1.9–2.3%
Formula
Irritation risk
Low
More about Sodium dna
Niacinamide~1.6–2%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationAntibacterialAnti-inflammatoryReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Butylene glycol~1.4–1.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Ceteareth-6 olivate~1.1–1.4%
Formula
Irritation risk
Low
Works for
Cleansing
More about Ceteareth-6 olivate
Cyclopentasiloxane~0.95–1.2%
Key active
Irritation risk
Low
Works for
MattifyingMoisturizing

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
1,2-hexanediol~0.65–0.95%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Cetyl peg/ppg-10/1 dimethicone~0.6–0.85%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

A type of silicone that helps water and oil mix together. Can help to soften upper layer of the skin

More about Cetyl peg/ppg-10/1 dimethicone
Acetyl hexapeptide-8~0.5–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Acetyl hexapeptide-8
Pentapeptide-18~0.5–0.75%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Pentapeptide-18
Oligopeptide-91 rh-oligopeptide-1~0.45–0.7%
Formula
Adenosine~0.45–0.7%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Panthenol~0.45–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Hyaluronic acid~0.4–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Squalane~0.45–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Anemarrhena asphodeloides root extract~0.3–0.6%
Formula
Irritation risk
Low
Works for
Anti-oxidation

A plant extract that might have some anti-oxidant properties

More about Anemarrhena asphodeloides root extract
Ceramide np~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np
Cetearyl olivate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Cetearyl olivate
Sorbitan olivate~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan olivate
Trehalose~0.25–0.5%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Caprylyl glycol~0.3–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Hydrogenated lecithin~0.25–0.5%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Lauryl glucoside~0.3–0.55%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Lauryl glucoside
Sodium chloride~0.25–0.45%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Cellulose gum~0.2–0.4%
Formula
Irritation risk
Low

Used to create thicker product consistency and stabilize emulsions

More about Cellulose gum
Lactic acid~0.15–0.3%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Evens skin toneMoisturizingExfoliationAnti-aging

An exfoliating and moisturizing alpha-hydroxy acid (AHA). Typically causes less irritation than other AHAs, for example, glycolic acid. At high concentrations (about 15%), lactic acid can help reduce lines and wrinkles. Recent studies show that lactic acid can support the "good" bacteria living on skin's surface (healthy skin microbiome)

More about Lactic acid
Ethylhexylglycerin~0.15–0.25%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hydrogenated polyisobutene~0.15–0.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Glycerin~0.15–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Sodium bicarbonate~0.15–0.3%
Formula
Irritation risk
Low

Helps regulate the product pH

More about Sodium bicarbonate
Sodium carbonate~0.05–0.1%
Formula
Irritation risk
Low

Helps regulate product's pH

More about Sodium carbonate
Citric acid~0.01–0.05%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Ingredient list view

Water, Propylene glycol, Caprylic/capric triglyceride, Isopropyl myristate, Polysorbate 80, Sodium dna, Niacinamide, Butylene glycol, Ceteareth-6 olivate, Cyclopentasiloxane, 1,2-hexanediol, Cetyl peg/ppg-10/1 dimethicone, Acetyl hexapeptide-8, Pentapeptide-18, Oligopeptide-91 rh-oligopeptide-1, Adenosine, Panthenol, Hyaluronic acid, Squalane, Anemarrhena asphodeloides root extract, Ceramide np, Cetearyl olivate, Sorbitan olivate, Trehalose, Caprylyl glycol, Hydrogenated lecithin, Lauryl glucoside, Sodium chloride, Cellulose gum, Lactic acid, Ethylhexylglycerin, Hydrogenated polyisobutene, Glycerin, Sodium bicarbonate, Sodium carbonate, Citric acid

Compare prices

Retailers ranked by price — lowest first.

Yesstyle
$13.90
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Amazon USPrice as of 11/7 12:11 GMT
$17.99
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
CELDYQUEPDRN 12% EGF Peptide SerumYOUR PRODUCTmixsoonBuy Mixsoon Premium Centella Asiatica Serum \in Australia - Korean Skincare and CosmeticsArenciaDeep Water Surge SerumCarenology 95RE:BLUE Deep Concentrate Ampoule
Match—83%81%81%
Price$13.90$53.67+$39.77$32.63+$18.73$26.99+$13.09
Shared key ingredients—6 of 138 of 137 of 13
Key difference—Copper Tripeptide-1Copper Tripeptide-1Copper Tripeptide-1
Irritancy Medium Low Medium Medium
Drying alcohol————
View product Shop Shop Shop

More alternatives: Dr.G R.E.D Blemish Bakuchiol Pore-Jet SerumGenabelle PDRN Dual Glow Serum Mist

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Product summary

"CELDYQUE - PDRN 12% EGF Peptide Serum" is effective for: Anti-aging, Moisturizing, Anti-blemish and Evens skin tone

Ingredient callouts

  • A good concentration of Niacinamide (1.60% - 2.00%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
  • Ceramides (ceramide np 0.35% - 0.65%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
  • Peptides (pentapeptide-18 0.50% - 0.75% and acetyl hexapeptide-8 0.50% - 0.80%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
  • Adenosine 0.45% - 0.70%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Humectants (glycerin 0.15% - 0.25%, trehalose 0.25% - 0.50%, hyaluronic acid 0.40% - 0.65%, panthenol 0.45% - 0.65% and acetyl hexapeptide-8 0.50% - 0.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 13.90$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 17 studies and safety reviews.

  1. 1
  2. 2
    Propylene Glycolpubmed.ncbi.nlm.nih.gov
  3. 3
  4. 4
  5. 5
  6. 6
CELDYQUE PDRN 12% EGF Peptide Serum
CELDYQUEPDRN 12% EGF Peptide Serum

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As an Amazon Associate, WIMJ earns from qualifying purchases.