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Blistex Deep Renewal Anti-Aging Lip Balm
Blistex

Blistex Deep Renewal Anti-Aging Lip Balm

Efficacy75/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Anti-aging
4 ingredients credited for this claim
Moderate support
What the product description says
“Deep Renewal is an advanced formula that delivers superb moisturization and is clinically shown to reduce the appearance of visible signs of aging and improve lip health and vitality with consistent use.”
Source: Walgreens

This product contains atelocollagen. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

AtelocollagenKey activeEffect: MediumA protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles~22–34%
UbiquinoneEffect: LowCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.35%
Dipalmitoyl hydroxyprolineEffect: LowIs claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness~3.7–5.5%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.1–0.4%
Moisturizing
16 ingredients credited for this claim
Good support
What the product description says
“Deep Renewal is an advanced formula that delivers superb moisturization and is clinically shown to reduce the appearance of visible signs of aging and improve lip health and vitality with consistent use.”
Source: Walgreens

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: sodium chondroitin sulfate, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: beeswax, dimethicone.

Jojoba estersKey active· EmollientEffect: HighAn emollient made of jojoba oil. Helps soften the skin and support its barrier function~1.6–2.5%
Sodium chondroitin sulfateKey active· HumectantEffect: HighIs naturally present in skin. Helps to attract water to its upper layer~0.15–0.65%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.15–0.55%
SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.15–0.7%
UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.35%
AtelocollagenKey activeEffect: HighA protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles~22–34%
BeeswaxKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~4.7–7.1%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish2%
Ricinus communis seed oilKey active· Emollient, OcclusiveEffect: HighA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency~0.35–0.85%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~2.9–4.4%
Dipalmitoyl hydroxyprolineKey activeEffect: MediumIs claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness~3.7–5.5%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.95–1.4%
Lanolin alcohol· EmollientEffect: LowHelps oil and water mix together. Can be irritating~1.4–2%
Pentylene glycol· EmollientEffect: LowUsed to preserve products, dissolve other ingredients and create a nice product texture~0.5–1.2%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~4–6.1%
PetrolatumUnder-dosedEffect: HighOne of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss~0.45–1.05%
Anti-oxidation
Not advertised by the brand · 4 ingredients credited for this claim
Strong support

This product contains antioxidants (ubiquinone) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

UbiquinoneKey activeEffect: HighCoenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen~0.1–0.35%
Dipalmitoyl hydroxyprolineEffect: LowIs claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness~3.7–5.5%
Tetrahexyldecyl ascorbateUnder-dosedEffect: HighBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.~0.1–0.4%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.1–0.4%

Can it cause trouble?

Irritancy
1 strong irritant: Aroma
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
AromaAn unspecified blend of fragrant irritating ingredientsHigh~2–3%est.
Butyl methoxydibenzoylmethaneAvobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.Medium3%
HomosalateA weak sunscreen that offers some protection against the sun rays that cause sunburn (UVB), but does not offer meaningful protection against protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen. When used in low concentrations, helps to stabilize the product formulationMedium9%
Jojoba estersAn emollient made of jojoba oil. Helps soften the skin and support its barrier functionMedium~1.6–2.5%est.
Lanolin alcoholHelps oil and water mix together. Can be irritatingMedium~1.4–2%est.
Pentaerythrityl tetraisostearateUsed to create a thicker product consistencyMedium~0.85–1.25%est.
Pentylene glycolUsed to preserve products, dissolve other ingredients and create a nice product textureMedium~0.5–1.2%est.
Ricinus communis seed oilA plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistencyMedium~0.35–0.85%est.
Sorbic acidA preservativeMedium~0.1–0.45%est.
Tetrahexyldecyl ascorbateBeing a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.Medium~0.1–0.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.1–0.4%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~2.9–4.4%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Butyl methoxydibenzoylmethane3%
Irritant · medium
Irritation risk
Medium
Works for
Sun protection

Avobenzone. An organic, or so-called "chemical" UV filter. Protects against both UVA and UVB rays. Needs to be combined with other filters in a formulation to be stable.

More about Butyl methoxydibenzoylmethane
Dimethicone2%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Homosalate9%
Irritant · medium
Irritation risk
Medium
Works for
Sun protection

A weak sunscreen that offers some protection against the sun rays that cause sunburn (UVB), but does not offer meaningful protection against protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen. When used in low concentrations, helps to stabilize the product formulation

More about Homosalate
Ethylhexyl salicylate4.4%
Formula
Irritation risk
Low
Works for
Sun protection

Octisalate. A UV filter. It offers some protection against the sun rays that cause sunburn (UVB), but does not protect against the most aging sun rays (UVA). It loses its effectiveness quickly when exposed to sunlight. It is an organic, or so called "chemical" sunscreen

More about Ethylhexyl salicylate
Atelocollagen~22–34%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A protein that helps to attract moisture to the upper layer of the skin and might be helpful in reducing fine lines and wrinkles

More about Atelocollagen
Beeswax~4.7–7.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Beeswax
Butylene glycol~4–6.1%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dipalmitoyl hydroxyproline~3.7–5.5%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-agingAnti-oxidation

Is claimed to stimulate collagen and elastin production, as well as work as an anti-oxidant. There is however not enough evidence for its effectiveness

More about Dipalmitoyl hydroxyproline
Ethylhexyl palmitate~2.9–4.4%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Aroma~2–3%
Irritant · high
Irritation risk
High

An unspecified blend of fragrant irritating ingredients

More about Aroma
Jojoba esters~1.6–2.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

An emollient made of jojoba oil. Helps soften the skin and support its barrier function

More about Jojoba esters
Lanolin alcohol~1.4–2%
Irritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Helps oil and water mix together. Can be irritating

More about Lanolin alcohol
Microcrystalline wax~1.1–1.7%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Microcrystalline wax
Octyldodecanol~0.95–1.4%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Pentaerythrityl tetraisostearate~0.85–1.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to create a thicker product consistency

More about Pentaerythrityl tetraisostearate
Pentylene glycol~0.5–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to preserve products, dissolve other ingredients and create a nice product texture

More about Pentylene glycol
Petrolatum~0.45–1.05%
Under-dosed
Irritation risk
Low
Works for
Moisturizing

One of the most effective and the most studied occlusive ingredients that creates a protective layer on top of the skin preventing moisture loss

More about Petrolatum
Phenoxyethanol~0.35–0.85%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polybutene~0.35–0.8%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Polybutene
Ricinus communis seed oil~0.35–0.85%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatory

A plant oil that can help soften the skin. It might be helpful in calming down inflammation, but solid research is lacking. Is often used in lip products to create the needed product consistency

More about Ricinus communis seed oil
Saccharin~0.2–0.75%
Formula
Irritation risk
Low
More about Saccharin
Silica dimethyl silylate~0.35–0.75%
Formula
Irritation risk
Low

Used to create a thicker product consistency

More about Silica dimethyl silylate
Sodium chondroitin sulfate~0.15–0.65%
Key active
Irritation risk
Low
Works for
Moisturizing

Is naturally present in skin. Helps to attract water to its upper layer

More about Sodium chondroitin sulfate
Sodium hyaluronate~0.15–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Sorbic acid~0.1–0.45%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sorbic acid
Squalane~0.15–0.7%
Key active
Irritation risk
Low
Works for
Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane
Tetrahexyldecyl ascorbate~0.1–0.4%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
Anti-oxidationEvens skin toneAnti-aging

Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.

More about Tetrahexyldecyl ascorbate
Tocopheryl acetate~0.1–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Ubiquinone~0.1–0.35%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-aging

Coenzyme Q10. It helps neutralize free radicals in skin, improves skin hydration and might be helpful agains fine lines and wrinkles. It can be an allergen

More about Ubiquinone
Ingredient list view

Butyl methoxydibenzoylmethane, Dimethicone, Homosalate, Ethylhexyl salicylate, Atelocollagen, Beeswax, Butylene glycol, Dipalmitoyl hydroxyproline, Ethylhexyl palmitate, Aroma, Jojoba esters, Lanolin alcohol, Microcrystalline wax, Octyldodecanol, Pentaerythrityl tetraisostearate, Pentylene glycol, Petrolatum, Phenoxyethanol, Polybutene, Ricinus communis seed oil, Saccharin, Silica dimethyl silylate, Sodium chondroitin sulfate, Sodium hyaluronate, Sorbic acid, Squalane, Tetrahexyldecyl ascorbate, Tocopheryl acetate, Ubiquinone

Compare prices

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Walgreens
$4.29
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Amazon USPrice as of 10/9/2026 21:58 GMT
$35.43
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

  1. 1
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  2. 2
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  3. 3
    Opinion on Homosalate - Scientific Committee on Consumer Products ec.europa.eu
  4. 4
    The Efficacy and Safety of Succinylated Atelocollagen and Adenosine for the Treatment of Periorbital Wrinklesscirp.org
  5. 5
    Contact Sensitization to Emulsifying Agents: An Underrated Issue?journals.lww.com
  6. 6
    Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmeticsncbi.nlm.nih.gov
Blistex Deep Renewal Anti-Aging Lip Balm
BlistexDeep Renewal Anti-Aging Lip Balm
Buy at Walgreens$4.29$35.43as of 10/9 21:58 GMT

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Walgreens$4.29$35.43as of 10/9 21:58 GMT

As an Amazon Associate, WIMJ earns from qualifying purchases.