BIOTHERM BLUE THERAPY ANTI-AGING NIGHT CREAM

BIOTHERM BLUE THERAPY ANTI-AGING NIGHT CREAM

Efficacy100/100IrritancyMedium
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Works for

2 of 2 advertised claims delivered

Moisturizing
Paraffinum liquidum, 2-oleamido-1,3-octadecanediol + 24 more
Strong evidence
What the product description says
“BLUE THERAPY ANTI-AGING NIGHT CREAM”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, glyceryl acrylate/acrylic acid copolymer.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: cera alba, cera microcristallina.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: paraffinum liquidum

Paraffinum liquidumHero· Emollient, OcclusiveEffect: HighMineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function~1–1.2%
2-oleamido-1,3-octadecanediolKey activeEffect: HighHelps soften the upper layer of the skin and slow down the water loss over time~0.25–0.45%
Cera albaKey active· Emollient, OcclusiveEffect: HighForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen~0.75–1.1%
Oryza sativa bran oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and might have some anti-oxidant properties~0.2–0.35%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.4–3%
Cera microcristallinaKey active· Emollient, OcclusiveEffect: HighHelps to soften the upper layer of the skin, reduce water loss from its surface and create a thicker product consistency~0.5–0.75%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%
Glyceryl acrylate/acrylic acid copolymerKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency~0.3–0.5%
Laminaria ochroleuca extractKey activeEffect: HighHelps attract water to the upper layer of the skin~0.25–0.45%
Zea mays oilKey activeEffect: HighA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function~0.4–0.6%
Hydroxypropyl tetrahydropyrantriolKey activeEffect: HighA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating~0.25–0.45%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~2–2.4%
Elaeis guineensis oilKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~1.2–1.5%
MaltitolKey active· HumectantEffect: MediumHelps attract water to the upper layer of the skin~0.2–0.4%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.2–0.35%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.7–2.1%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~3.1–3.7%
Paraffin· OcclusiveEffect: LowPrevents water loss from the skin surface and thickens the product consistency~0.3–0.55%
Isohexadecane· EmollientEffect: LowImproves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent~0.35–0.65%
Propylene glycol· HumectantEffect: LowHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating~0.25–0.45%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.5–0.75%
Hydrogenated polyisobutene· Emollient, OcclusiveEffect: LowUsed to improve the product consistency and soften the upper layer of the skin~5.1–6.3%
Moringa pterygosperma seed extractEffect: LowMight help attract water to the upper layer of the skin~0.25–0.45%
Myristyl myristateUnder-dosedEffect: HighAn emollient. Is not recommended for acne-prone skin as it can be comedogenic~0.55–0.85%
Prunus armeniaca kernel oilUnder-dosedEffect: HighAn emollient that helps soften the skin~0.3–0.55%
Anti-aging
Adenosine
Strong evidence
What the product description says
“BLUE THERAPY ANTI-AGING NIGHT CREAM”
From product name

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%
Exfoliation
Not advertised by the brand · Capryloyl salicylic acid
Strong evidence

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: capryloyl salicylic acid.

Capryloyl salicylic acidKey activeEffect: High~0.25–0.45%
Evens skin tone
Not advertised by the brand · Capryloyl salicylic acid
Moderate evidence

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: capryloyl salicylic acid.

Capryloyl salicylic acidKey activeEffect: Medium~0.25–0.45%

Can it cause trouble?

Irritancy
1 strong irritant: Parfum
Medium risk
We flagged 12 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Propylene glycolHelps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritatingHigh~0.25–0.45%est.
Hydroxypropyl tetrahydropyrantriolA sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritatingHigh~0.25–0.45%est.
Capryloyl salicylic acid—High~0.25–0.45%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.1–0.15%est.
Zea mays starchUsed to thicken the product's consistencyMedium~1.4–1.8%est.
Cera albaForms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergenMedium~0.75–1.1%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenicMedium~0.55–0.85%est.
Sorbitan tristearateHelps oil and water mix togetherMedium~0.3–0.6%est.
Glyceryl acrylate/acrylic acid copolymerHelps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistencyMedium~0.3–0.5%est.
Prunus armeniaca kernel oilAn emollient that helps soften the skinMedium~0.3–0.55%est.
ChlorphenesinA preservativeMedium~0.16–0.32%est.
Disodium edtaStabilizes the product formulationMedium~0.25–0.45%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Zea mays starchUsed to thicken the product's consistency3/5~1.4–1.8%est.
Myristyl myristateAn emollient. Is not recommended for acne-prone skin as it can be comedogenic3/5~0.55–0.85%est.
Zea mays oilA good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function3/5~0.4–0.6%est.
Laminaria ochroleuca extractHelps attract water to the upper layer of the skin3/5~0.25–0.45%est.
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Hydrogenated polyisobutene~5.1–6.3%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to improve the product consistency and soften the upper layer of the skin

More about Hydrogenated polyisobutene
Glycerin~4–4.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Butylene glycol~3.1–3.7%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Dimethicone~2.4–3%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Cetyl alcohol~2–2.4%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Glyceryl stearate~1.7–2.1%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Zea mays starch~1.4–1.8%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Mattifying

Used to thicken the product's consistency

More about Zea mays starch
Elaeis guineensis oil~1.2–1.5%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin

More about Elaeis guineensis oil
Paraffinum liquidum~1–1.2%
Hero · Moisturizing
Irritation risk
Low
Works for
Moisturizing

Mineral oil. One of the most effective and well studied occlusive and emollient moisturizing ingredients. Helps reduce moisture loss in skin and repair skin barrier function

More about Paraffinum liquidum
Peg-100 stearate~0.8–1.15%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Cera alba~0.75–1.1%
Key activeIrritant · medium
Irritation risk
Medium
Works for
CleansingMoisturizing

Forms a protective barrier that holds water and keeps dry skin hydrated. Keeps an emulsion from separating into its oil and liquid components, and increases the thickness of a product. Can be an allergen

More about Cera alba
Sorbitol~0.5–0.75%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Myristyl myristate~0.55–0.85%
Under-dosedComedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

An emollient. Is not recommended for acne-prone skin as it can be comedogenic

More about Myristyl myristate
Zea mays oil~0.4–0.6%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingCleansing

A good moisturizing plant oil. Due to the high linoleic acid content, it helps soften the upper layer of the skin, reduce water loss and support skin barrier function

More about Zea mays oil
Peg-14m~0.45–0.65%
Formula
Irritation risk
Low
More about Peg-14m
Cera microcristallina~0.5–0.75%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps to soften the upper layer of the skin, reduce water loss from its surface and create a thicker product consistency

More about Cera microcristallina
Paraffin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Prevents water loss from the skin surface and thickens the product consistency

More about Paraffin
Algae~0.3–0.55%
Formula
Irritation risk
Low
More about Algae
Sorbitan tristearate~0.3–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Sorbitan tristearate
Glyceryl acrylate/acrylic acid copolymer~0.3–0.5%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin and provide a longer-lasting hydration. Can create a thicker product consistency

More about Glyceryl acrylate/acrylic acid copolymer
Dimethyl isosorbide~0.25–0.5%
Formula
Irritation risk
Low

Used to dissolve other ingredients in a product and can enhance their ability to penetrate the skin

More about Dimethyl isosorbide
Isohexadecane~0.35–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Improves the texture of the product and helps soften the skin. Helps oil and water mix together and can be used as a cleansing agent

More about Isohexadecane
Laminaria ochroleuca extract~0.25–0.45%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Laminaria ochroleuca extract
Sodium hydroxide~0.25–0.5%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Moringa pterygosperma seed extract~0.25–0.45%
Formula
Irritation risk
Low
Works for
Moisturizing

Might help attract water to the upper layer of the skin

More about Moringa pterygosperma seed extract
2-oleamido-1,3-octadecanediol~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and slow down the water loss over time

More about 2-oleamido-1,3-octadecanediol
Phenoxyethanol~0.25–0.5%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Prunus armeniaca kernel oil~0.3–0.55%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

An emollient that helps soften the skin

More about Prunus armeniaca kernel oil
Adenosine~0.25–0.45%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Chlorphenesin~0.16–0.32%
Irritant · medium
Irritation risk
Medium

A preservative

More about Chlorphenesin
Disodium edta~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Propylene glycol~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Moisturizing

Helps oil and water mix together and can enhance the penetration of other ingredients into the skin. It can be irritating

More about Propylene glycol
Hydroxypropyl tetrahydropyrantriol~0.25–0.45%
Key activeIrritant · high
Irritation risk
High
Works for
Moisturizing

A sugar-derived compound that helps to attract water to the upper layer of the skin and might be able to stimulate synthesis of skin's own moisturizing factors, but solid research is lacking. It could be irritating

More about Hydroxypropyl tetrahydropyrantriol
Capryloyl salicylic acid~0.25–0.45%
Key activeIrritant · high
Irritation risk
High
Works for
ExfoliationEvens skin toneAnti-blemish
More about Capryloyl salicylic acid
Vitreoscilla ferment~0.25–0.4%
Formula
Passiflora edulis oil
Not recognized
Xanthan gum~0.25–0.4%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Maltitol~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Maltitol
Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate~0.2–0.4%
Formula
Irritation risk
Low

Used to increase stability of product formulations

More about Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate
Octyldodecanol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.15–0.3%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Polysorbate 80~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps water and oil mix together

More about Polysorbate 80
Oryza sativa bran oil~0.2–0.35%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and might have some anti-oxidant properties

More about Oryza sativa bran oil
Parfum~0.1–0.15%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
F.i.l. b160851/7
Not recognized
Ingredient list view

Water, Hydrogenated polyisobutene, Glycerin, Butylene glycol, Dimethicone, Cetyl alcohol, Glyceryl stearate, Zea mays starch, Elaeis guineensis oil, Paraffinum liquidum, Peg-100 stearate, Cera alba, Sorbitol, Myristyl myristate, Zea mays oil, Peg-14m, Cera microcristallina, Paraffin, Algae, Sorbitan tristearate, Glyceryl acrylate/acrylic acid copolymer, Dimethyl isosorbide, Isohexadecane, Laminaria ochroleuca extract, Sodium hydroxide, Moringa pterygosperma seed extract, 2-oleamido-1,3-octadecanediol, Phenoxyethanol, Prunus armeniaca kernel oil, Adenosine, Chlorphenesin, Disodium edta, Propylene glycol, Hydroxypropyl tetrahydropyrantriol, Capryloyl salicylic acid, Vitreoscilla ferment, Unknown, Xanthan gum, Maltitol, Pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, Octyldodecanol, Acrylamide/sodium acryloyldimethyltaurate copolymer, Polysorbate 80, Oryza sativa bran oil, Parfum, Unknown

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Biotherm
$88.00
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Amazon USPrice as of 10/28/2026 15:12 GMT
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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
BIOTHERMBLUE THERAPY ANTI-AGING NIGHT CREAMYOUR PRODUCTShu UemuraUltime8 Sublime Beauty Oil In CreamL'Oréal ParisCell Renewal Midnight Cream Anti-Aging Night Moisturizer with Antioxidants, Fragrance FreeVichyNeovadiol Rose Platinum Night Cream
Match—53%52%51%
Price$56.06$115.00+$58.94$36.99−$19.07$37.39−$18.67
Shared key ingredients—7 of 155 of 158 of 15
Key difference—Carthamus Tinctorius Seed OilPanthenolCalcium Pca
Irritancy Medium High Medium Medium
Drying alcohol——— Contains drying alcohol
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Product summary

"BIOTHERM - BLUE THERAPY ANTI-AGING NIGHT CREAM" has a good moisturizing formula. To work well, any moisturizer needs to include a combination of water-binding and emollient ingredients. BIOTHERM - BLUE THERAPY ANTI-AGING NIGHT CREAM ticks this box. Humectants in this product (glycerin, glyceryl acrylate/acrylic acid copolymer, maltitol, butylene glycol and propylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (paraffinum liquidum, oryza sativa bran oil, cera alba, cera microcristallina and dimethicone) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: apricot kernel oil and myristyl myristate

Irritation risk

This moisturizer contains some common irritants, including those without a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Price

The product retails from 78.75CA$ up to 105.00CA$ in Canada and for 85.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 21 studies and safety reviews.

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BIOTHERM BLUE THERAPY ANTI-AGING NIGHT CREAM
BIOTHERMBLUE THERAPY ANTI-AGING NIGHT CREAM

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As an Amazon Associate, WIMJ earns from qualifying purchases.