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Bionike Defense hydractive cream
Bionike

Bionike Defense hydractive cream

Efficacy100/100IrritancyMedium
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Works for

1 of 1 advertised claim delivered

Moisturizing
Ceramide ns, Sodium lactate + 28 more
Strong evidence
What the product description says
“Defense hydractive cream”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: carnosine, diglycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: bis-diglyceryl polyacyladipate-2, dimethicone.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide ns

Sodium lactateKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product~0.25–0.45%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~0.3–0.6%
TrehaloseKey active· HumectantEffect: HighA sugar that attracts water to the upper layer of the skin~0.25–0.45%
PhytosterolsKey active· EmollientEffect: HighLipids that work as an emollient and can be helpful in repairing skin barrier function~0.3–0.55%
Simmondsia chinensis seed oilKey active· Emollient, OcclusiveEffect: HighSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.~2–2.4%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.25–0.45%
Sodium pcaKey active· HumectantEffect: HighNaturally present in skin and helps to attract water to its upper layer~0.3–0.6%
Imperata cylindrica root extractKey active· HumectantEffect: HighA plat extract that might help neutralize free radicals in skin and attract water to its upper layer~0.95–1.15%
DimethiconolKey active· Emollient, OcclusiveEffect: HighA silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time~0.3–0.55%
CarnosineKey active· HumectantEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.7–1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.7–5.7%
Ceramide nsHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.3–0.5%
Hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%
Hydrolyzed hyaluronic acidKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin~0.25–0.45%
Bis-diglyceryl polyacyladipate-2Key active· Emollient, OcclusiveEffect: HighHelps soften the upper layer of the skin and reduce water loss from its surface~1.7–2.1%
DiglycerinKey active· HumectantEffect: HighHelps attract water to the upper layer of the skin~3–3.7%
TrihydroxystearinKey activeEffect: MediumHelps soften the upper layer of the skin and improve the product texture~0.15–0.3%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.6–0.95%
CyclopentasiloxaneKey active· EmollientEffect: MediumA silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin~4.2–5.1%
Ethylhexyl palmitateKey active· EmollientEffect: MediumAn emollient that helps soften the skin and create a nice product texture~2.4–2.9%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.45–0.7%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.5–1.8%
Isopropyl palmitate· EmollientEffect: LowHelps soften the upper layer of the skin and create a thicker product consistency~1.2–1.5%
Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.2–0.35%
Peg-8· HumectantEffect: LowUsed to create a nice product consistency~0.25–0.45%
Sorbitol· HumectantEffect: LowHelps attract water to the upper layer of the skin and improves the product texture~0.45–0.65%
Bis-peg-18 methyl ether dimethyl silane· Humectant, EmollientEffect: LowA type of silicone that helps soften the upper layer of the skin and create a nice product texture~0.45–0.65%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.3–0.55%
C13-14 isoparaffin· EmollientEffect: LowHelps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency~0.3–0.55%
Butyrospermum parkii butterUnder-dosedEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.65–0.95%
Anti-oxidation
Not advertised by the brand · Carnosine, Imperata cylindrica root extract + 1 more
Strong evidence

This product contains antioxidants (carnosine) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

The following ingredients - imperata cylindrica root extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.

CarnosineKey activeEffect: HighA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.7–1%
Imperata cylindrica root extractKey activeEffect: MediumA plat extract that might help neutralize free radicals in skin and attract water to its upper layer~0.95–1.15%
Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.65–0.95%
Anti-aging
Not advertised by the brand · Carnosine, Hyaluronic acid + 1 more
Moderate evidence

This product contains carnosine. This ingredient might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

CarnosineKey activeEffect: MediumA type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage~0.7–1%
Hyaluronic acidEffect: LowOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation~0.25–0.45%
Butyrospermum parkii butterEffect: Low, below effective doseA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~0.65–0.95%

Can it cause trouble?

Irritancy
1 strong irritant: Rosa centifolia flower water
Medium risk
We flagged 14 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Rosa centifolia flower water—High~0.25–0.45%est.
Decyl glucosideHelps oil and water mix together. Can be irritatingHigh~0.25–0.45%est.
Simmondsia chinensis seed oilSoftens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.Medium~2–2.4%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistencyMedium~1.2–1.5%est.
Imperata cylindrica root extractA plat extract that might help neutralize free radicals in skin and attract water to its upper layerMedium~0.95–1.15%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.45–0.7%est.
Acrylates/c10-30 alkyl acrylate crosspolymerMaintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix togetherMedium~0.4–0.6%est.
Sodium lactateHelps attract water to the upper layer of the skin. Is often used to adjust the pH level of the productMedium~0.25–0.45%est.
PhytosterolsLipids that work as an emollient and can be helpful in repairing skin barrier functionMedium~0.3–0.55%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.4%est.
Peg-8Used to create a nice product consistencyMedium~0.25–0.45%est.
Caprylhydroxamic acidA preservativeMedium~0.2–0.35%est.
Laureth-7Helps oil and water mix togetherMedium~0.2–0.4%est.
Trisodium ethylenediamine disuccinateUsed to improve stability of the formulationMedium~0.05–0.15%est.
Comedogenic
4 ingredients rated 2 or more on the 0–5 pore-clogging scale
4 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ethylhexyl palmitateAn emollient that helps soften the skin and create a nice product texture3/5~2.4–2.9%est.
Isopropyl palmitateHelps soften the upper layer of the skin and create a thicker product consistency3/5~1.2–1.5%est.
Butyrospermum parkii butterA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~0.65–0.95%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.6–0.95%est.
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Alternatives
The closest match we found
Hydrating Barrier Cream
silkier Hydrating Barrier Cream
Closest match57% match
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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Glycerin~4.7–5.7%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Cyclopentasiloxane~4.2–5.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin

More about Cyclopentasiloxane
Diglycerin~3–3.7%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin

More about Diglycerin
Ethylhexyl palmitate~2.4–2.9%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

An emollient that helps soften the skin and create a nice product texture

More about Ethylhexyl palmitate
Simmondsia chinensis seed oil~2–2.4%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Softens the upper layer of skin and helps restore the healthy skin barrier. Has shown to help calm down inflammation in skin. It is a stable oil, meaning that it retains its properties even when exposed to air.

More about Simmondsia chinensis seed oil
Bis-diglyceryl polyacyladipate-2~1.7–2.1%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and reduce water loss from its surface

More about Bis-diglyceryl polyacyladipate-2
Glyceryl stearate~1.5–1.8%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Isopropyl palmitate~1.2–1.5%
Comedogenic 3/5Irritant · medium
Irritation risk
Medium
Comedogenicity
3/5
Works for
Moisturizing

Helps soften the upper layer of the skin and create a thicker product consistency

More about Isopropyl palmitate
Imperata cylindrica root extract~0.95–1.15%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationAnti-inflammatory

A plat extract that might help neutralize free radicals in skin and attract water to its upper layer

More about Imperata cylindrica root extract
Carnosine~0.7–1%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingAnti-aging

A type of peptide. It attracts water to the upper layer of the skin. It can help neutralize free radicals in skin combatting the sun damage

More about Carnosine
Butyrospermum parkii butter~0.65–0.95%
Under-dosedComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
MoisturizingAnti-oxidationAnti-aging

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter
Cetearyl alcohol~0.6–0.95%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Peg-100 stearate~0.55–0.85%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix togehter and creates a nice product texture

More about Peg-100 stearate
Caprylyl glycol~0.45–0.7%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Sorbitol~0.45–0.65%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the upper layer of the skin and improves the product texture

More about Sorbitol
Bis-peg-18 methyl ether dimethyl silane~0.45–0.65%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

A type of silicone that helps soften the upper layer of the skin and create a nice product texture

More about Bis-peg-18 methyl ether dimethyl silane
Acrylates/c10-30 alkyl acrylate crosspolymer~0.4–0.6%
Irritant · medium
Irritation risk
Medium

Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together

More about Acrylates/c10-30 alkyl acrylate crosspolymer
Sodium pca~0.3–0.6%
Key active
Irritation risk
Low
Works for
Moisturizing

Naturally present in skin and helps to attract water to its upper layer

More about Sodium pca
Butylene glycol~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Ammonium acryloyldimethyltaurate/vp copolymer~0.3–0.55%
Formula
Irritation risk
Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer
Acrylamide/sodium acryloyldimethyltaurate copolymer~0.25–0.5%
Formula
Irritation risk
Low

Helps water and oil mix together and create gel-like textures

More about Acrylamide/sodium acryloyldimethyltaurate copolymer
Dimethiconol~0.3–0.55%
Key active
Irritation risk
Low
Works for
Moisturizing

A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time

More about Dimethiconol
Dimethicone~0.3–0.6%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
C13-14 isoparaffin~0.3–0.55%
Formula
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin, dissolve other ingredients and create a thicker product consistency

More about C13-14 isoparaffin
Glutamine~0.25–0.45%
Formula
Irritation risk
Low
More about Glutamine
Cistus incanus flower/leaf/stem extract~0.25–0.45%
Formula
Irritation risk
Low
More about Cistus incanus flower/leaf/stem extract
Gynostemma pentaphyllum leaf/stem extract~0.3–0.55%
Formula
Irritation risk
Low
More about Gynostemma pentaphyllum leaf/stem extract
Sodium hyaluronate~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Hyaluronic acid~0.25–0.45%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-aging

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. Naturally present in skin. Typically has large molecule size unless advertised otherwise on the product label. Helps support skin's barrier function and may help to reduce inflammation

More about Hyaluronic acid
Hydrolyzed hyaluronic acid~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin. A version of it is naturally present in skin

More about Hydrolyzed hyaluronic acid
Ceramide ns~0.3–0.5%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide ns
Rosa centifolia flower water~0.25–0.45%
Irritant · high
Irritation risk
High
More about Rosa centifolia flower water
Sodium lactate~0.25–0.45%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps attract water to the upper layer of the skin. Is often used to adjust the pH level of the product

More about Sodium lactate
Trehalose~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

A sugar that attracts water to the upper layer of the skin

More about Trehalose
Phytosterols~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

Lipids that work as an emollient and can be helpful in repairing skin barrier function

More about Phytosterols
Sclerotium gum~0.25–0.45%
Formula
Irritation risk
Low

Used to create gel-like formulas and stabilize emulsions

More about Sclerotium gum
Carbomer~0.25–0.45%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Citric acid~0.25–0.4%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Peg-8~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Used to create a nice product consistency

More about Peg-8
Alteromonas ferment filtrate~0.2–0.4%
Formula
Irritation risk
Low
More about Alteromonas ferment filtrate
Caprylhydroxamic acid~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Caprylhydroxamic acid
Laureth-7~0.2–0.4%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Laureth-7
Hydrogenated lecithin~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps to retain moisture by creating a protective barrier on the skin. Rich in fatty acids. Improves product texture and helps with the penetration of other ingredients.

More about Hydrogenated lecithin
Decyl glucoside~0.25–0.45%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together. Can be irritating

More about Decyl glucoside
Octyldodecanol~0.2–0.35%
Formula
Irritation risk
Low
Works for
Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol
Trihydroxystearin~0.15–0.3%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps soften the upper layer of the skin and improve the product texture

More about Trihydroxystearin
Glucomannan~0.1–0.2%
Formula
Irritation risk
Low
More about Glucomannan
Trisodium ethylenediamine disuccinate~0.05–0.15%
Irritant · medium
Irritation risk
Medium

Used to improve stability of the formulation

More about Trisodium ethylenediamine disuccinate
Ingredient list view

Water, Glycerin, Cyclopentasiloxane, Diglycerin, Ethylhexyl palmitate, Simmondsia chinensis seed oil, Bis-diglyceryl polyacyladipate-2, Glyceryl stearate, Isopropyl palmitate, Imperata cylindrica root extract, Carnosine, Butyrospermum parkii butter, Cetearyl alcohol, Peg-100 stearate, Caprylyl glycol, Sorbitol, Bis-peg-18 methyl ether dimethyl silane, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium pca, Butylene glycol, Ammonium acryloyldimethyltaurate/vp copolymer, Acrylamide/sodium acryloyldimethyltaurate copolymer, Dimethiconol, Dimethicone, C13-14 isoparaffin, Glutamine, Cistus incanus flower/leaf/stem extract, Gynostemma pentaphyllum leaf/stem extract, Sodium hyaluronate, Hyaluronic acid, Hydrolyzed hyaluronic acid, Ceramide ns, Rosa centifolia flower water, Sodium lactate, Trehalose, Phytosterols, Sclerotium gum, Carbomer, Citric acid, Peg-8, Alteromonas ferment filtrate, Caprylhydroxamic acid, Laureth-7, Hydrogenated lecithin, Decyl glucoside, Octyldodecanol, Trihydroxystearin, Glucomannan, Trisodium ethylenediamine disuccinate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
BionikeDefense hydractive creamYOUR PRODUCTsilkierHydrating Barrier CreamRevolutionCeramides Moisture CreamREVOLUTION SKINCARECeramides Moisture Cream
Match—57%55%55%
Price——$12.02$12.02
Shared key ingredients—6 of 185 of 185 of 18
Key difference—Ceramide ApCeramide NpCeramide Np
Irritancy Medium Low Low Low
Drying alcohol————
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Product summary

"Bionike - Defense hydractive cream" has a good moisturizing formula. As we expect from a proper moisturizer, the formula includes a combo of effective humectants and emollients. These are the two different types of ingredients that are essential for improving the skin hydration and supporting a healthy skin barrier. Humectants in this product (carnosine, diglycerin, glycerin, hyaluronic acid and hydrolyzed hyaluronic acid) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Emollients in this formulation (ceramide ns, phytosterols, bis-diglyceryl polyacyladipate-2, dimethicone and dimethiconol) help to reduce the moisture loss from the skin. They also soften the skin surface and relieve the feeling of dryness and tightness.

Ingredient callouts

  • As a plus, this moisturizer also contains Ceramides (ceramide ns 0.30% - 0.50%). Ceramides are a type of lipids that our skin produces itself. They are a building block of the skin's barrier. Ceramides used in skincare are synthetic or extracted from plants. They work well for softening the skin surface and "patch holes" in the skin's barrier.
This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: butyrospermum parkii butter

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be medium. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Safety assessment of bis-diglyceryl polyacyladipate-2 and bis-diglyceryl polyacyladipate-1 as used in cosmeticsncbi.nlm.nih.gov
  3. 3
    Final Report on the Safety Assessment of Isopropyl Isostearatejournals.sagepub.com
  4. 4
    Allergic contact dermatitis from grassespubmed.ncbi.nlm.nih.gov
  5. 5
    Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care productssciencedirect.com
  6. 6
    Dimethicone as a protective ingredient in topical medicationsjaad.org
Bionike Defense hydractive cream
BionikeDefense hydractive cream
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