PRODUCT REVIEW
Bioderma Sebium Global Intensive Purifying Cream For Acne-Prone Skin
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Price as of 7/8/2025 0:20 GMT.
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Product summary
What can the product work for?
Anti-blemish
What does the product description say?
Sebium Global Intensive Purifying Cream For Acne-Prone Skin
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
Irritation risk:
Concentration: Effectiveness: HIGH
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
ginkgo biloba leaf extract
0.4% -
0.6%
Irritation risk:
Concentration: Effectiveness:
LOW
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
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Anti-aging
What does the product description say?
Revive skin’s youthful radiance with the Pore Refiner from Bioderma ’s anti-blemish range, Sébium; a dermatological correcting treatment that tightens dilated pores and improves skin texture.
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
rhamnose
0.45% -
0.7%
Irritation risk:
Concentration: Effectiveness:
LOW
Helps oil and water mix together. It also helps attract water to the upper layer of the skin
zinc gluconate
1.4% -
1.7%
Irritation risk:
Concentration: Effectiveness:
LOW
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Evens skin tone
What does the product description say?
It is rich in irritating comedogenic fatty acids that can cause recurring spots and blackheads to appear.
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
glycyrrhetinic acid
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation
zinc gluconate
1.4% -
1.7%
Irritation risk:
Concentration: Effectiveness:
LOW
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
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Moisturizing
What does the product description say?
STEP 3 Can be used on its own or layered with an additional moisturizer.
zinc gluconate
1.4% -
1.7%
Irritation risk:
Concentration: Effectiveness: HIGH
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
fructooligosaccharides
0.45% -
0.65%
Irritation risk:
Concentration: Effectiveness: HIGH
Help attract water to the upper layer of the skin
glycerin
1.8% -
2.2%
Irritation risk:
Concentration: Effectiveness: HIGH
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
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Exfoliation
Irritation risk:
Concentration: Effectiveness: HIGH
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
zinc gluconate
1.4% -
1.7%
Irritation risk:
Concentration: Effectiveness:
LOW
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Anti-oxidation
bakuchiol
0.2% -
0.35%
Irritation risk:
Concentration: Effectiveness: HIGH
A plant extract that is, though different in chemical structure, acts similar to retinoids. First studies show that it can help reduce fine lines and wrinkles, improve skin tone, reduce clogged pores and blemishes, and reduce inflammation. There is no conclusive evidence that bakuchiol is as effective as retinol however. The study that directly compared retinol with bakuchiol used bakuchiol applied twice daily compared to once per day for the retinol. According to this study, bakuchiol is less irritating than retinol. Bakuchiol is extracted from seeds of Babchi plant. Other parts of the plant contain coumarins that could cause allergic and irritant reactions. These compounds should be removed in the extraction process when bakuchiol is produced, but it is a good idea to be cautious and stay away from products that include the Babchi plant extracts other than purified bakuchiol to avoid irritation
glycyrrhetinic acid
0.2% -
0.4%
Irritation risk:
Concentration: Effectiveness: HIGH
Active compound of licorice root. Works to calm down inflammation, as an anti-oxidant, and might be helpful in lightening the skin and reducing hyperpigmentation
ginkgo biloba leaf extract
0.4% -
0.6%
Irritation risk:
Concentration: Effectiveness:
MEDIUM
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
Show more
Honesty check
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Evens skin tone | |
| Anti-blemish | |
| Moisturizing |
Total Promises Fulfilled score:
93/100.
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Can it cause trouble?
- Overall product irritation risk
- Acne & comedogenic risk ingredients: 1
Potential irritants
Irritation risk:
Works for:
Exfoliation,
Anti-blemish,
Anti-inflammatory,
Antibacterial,
Evens skin tone
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
ginkgo biloba leaf extract
0.4% -
0.6%
Irritation risk:
Works for:
Anti-oxidation,
Anti-blemish,
Antibacterial,
Anti-inflammatory
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
Show more
Comodogenic ingredients
laminaria ochroleuca extract
0.4% -
0.65%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps attract water to the upper layer of the skin
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| Common:
Other:
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| Irritancy | IRRITANCY
MEDIUM
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MEDIUM
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LOW
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LOW
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LOW
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LOW
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MEDIUM
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MEDIUM
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MEDIUM
| IRRITANCY
HIGH
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HIGH
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HIGH
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Ingredients & concentrations
All ingredients
Key Actives
zinc gluconate
1.4% -
1.7%
Irritation risk:
Works for:
Moisturizing,
Anti-aging,
Anti-oxidation,
Evens skin tone,
Anti-inflammatory,
Anti-blemish,
Exfoliation
Typically used to stabilize the product formulations. It is a salt of a polyhydroxy acid (PHA) and in larger concentrations, can help shed the dead cells from the skin surface revealing smoother skin. It can help attract water to the upper layer of the skin. Might to be helpful against acne and clogged pores. Could be helpful in neutralizing free radicals, but solid research is missing. Due to the zinc content, might help calm down inflammation in skin
Irritation risk:
Works for:
Exfoliation,
Anti-blemish,
Anti-inflammatory,
Antibacterial,
Evens skin tone
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
Show more
Potential irritants
Irritation risk:
Works for:
Exfoliation,
Anti-blemish,
Anti-inflammatory,
Antibacterial,
Evens skin tone
Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)
ginkgo biloba leaf extract
0.4% -
0.6%
Irritation risk:
Works for:
Anti-oxidation,
Anti-blemish,
Antibacterial,
Anti-inflammatory
A plant extract that might help neutralize free radicals and reduce inflammation in skin. It can be irritating
Show more
Comodogenic ingredients
laminaria ochroleuca extract
0.4% -
0.65%
Irritation risk: Comedogenicity: High
Works for:
Moisturizing
Helps attract water to the upper layer of the skin
All ingredients
dipropylene glycol
4.4% -
5.4%
Irritation risk:
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
Show more
Ingredient list view
Water, C12-13 alkyl lactate, Dipropylene glycol, Citric acid, Cyclopentasiloxane, Sodium hydroxide, Glycerin, Zinc gluconate, Methyl methacrylate crosspolymer, Salicylic acid, Arachidyl alcohol, Dimethicone, Mannitol, Xylitol, Rhamnose, Fructooligosaccharides, Laminaria ochroleuca extract, Ginkgo biloba leaf extract, Behenyl alcohol, Glyceryl stearate, Peg-100 stearate, Silica, Hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, Xanthan gum, Arachidyl glucoside, C30-45 alkyl cetearyl dimethicone crosspolymer, Glycyrrhetinic acid, Propylene glycol, Polysorbate 60, Caprylic/capric triglyceride, Bakuchiol, Squalane, Parfum
Sources
- Glycerol and the skin: holistic approach to its origin and functions
- Zinc salts in dermatology
- An overview of zinc and its importance in dermatology-Part II: The association of zinc with some dermatologic disorders
- Zinc, copper and manganese enhanced keratinocyte migration through a functional modulation of keratinocyte integrins
- Evaluation of the effects of topical zinc gluconate in wound healing
- A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen
- Applications of hydroxy acids: classification, mechanisms, and photoactivity
- Salicylic acid as a peeling agent: a comprehensive review
- Beta Hydroxy Acids
- A review of toxicity from topical salicylic acid preparations
- Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Study
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- Potentially beneficial effects of rhamnose on skin ageing: an in vitro and in vivo study
- Safety Assessment of Ginkgo biloba-Derived Ingredients as Used in Cosmetics
- Cosmeceutical Critique: Ginkgo Biloba
- Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application
- Effects of topical application of B‐Resorcinol and Glycyrrhetinic acid monotherapy and in combination with fractional CO2 laser treatment for benign hand hyperpigmentation treatment
- 18β-Glycyrrhetinic Acid and Glabridin Prevent Oxidative DNA Fragmentation in UVB-irradiated Human Keratinocyte Cultures
- Surfactants and experimental irritant contact dermatitis
- Propylene Glycol
- Skin-sensitizing and irritant properties of propylene glycol
- Bakuchiol in the Management of Acne-affected Skin
- Prospective, randomized, double‐blind assessment of topical bakuchiol and retinol for facial photoageing