Works for:
based on ingredients and %- Moisturizing
- Anti-oxidation
- Anti-blemish
- Anti-aging
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"BeautyBio - R45 The Reversal 3-Phase Retinol Booster System" is effective for: Anti-blemish, Moisturizing, Anti-aging, Evens skin tone and Exfoliation
Ingredient callouts
- this product contains an effective form of Retinoids (vitamin A): retinol 1.20% - 1.80%. Retinoids are potent multitasking actives. They work to improve and prevent early signs of aging, reduce hyperpigmentation (age spots and post-acne marks), and prevent inflamed blemishes and clogged pores. The downside of Retinoids is that they can be irritating. If you are not already using a Retinoid in your routine, it is best to start slowly and apply the Retinoid product only a few times per week. If your skin tolerates it well, you can gradually increase the frequency to daily.
- Peptides (myristoyl pentapeptide-17 0.10% - 0.35%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
- Humectants (sodium hyaluronate 0.05% - 0.30%, glycerin 0.15% - 0.55% and sodium hyaluronate 1.70% - 2.60%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
About the brand
According to Cruelty-Free Kitty "BeautyBio" is cruelty free and so is its parent company.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains retinol.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: myristoyl pentapeptide-17.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: retinol. This ingredient is used for treating acne and can have a noticeable effect.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Anti-oxidation
This product contains antioxidants (retinol) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - camellia sinensis extract also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Tea extract. Might be helpful in neutralizing free radicals in skin
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: retinol.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: retinol.
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Moisturizing
What does the product description say?
Growth Factor Stimulant Serum Peptide complex that strengthens skin's proteins, increases hydration levels and fortifies skin against free radical damage
Source: Ulta
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: dimethicone, dimethiconol.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: myristoyl pentapeptide-17
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A silicone that mixes with water creating nice light-weight product texture
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
Used to preserve products, dissolve other ingredients and create a nice product texture
Lecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin
Helps preserve products and creates a nice product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing |
Total Promises Fulfilled score: 100/100.
Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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| Product | Similarity | Price | Irritancy |
|---|---|---|---|
 BeautyBio R45 The Reversal 3-Phase Retinol Booster System | Current | - | |
 SENTÉ Favorite Serums Duo | 85% | $316.00 | |
 Beauty Pie Super Retinol Ceramide-Boost Anti-aging Face Serum | 77% | $16.50 | |
 Ultraceuticals Ultra A Skin Perfecting Serum | 77% | $159.00 | |
 No7 Advanced Retinol 1.5% Complex Night Concentrate | 77% | $39.99 | |
 First Aid Beauty 0.3% Retinol Complex Serum with Peptides | 77% | - |
Key Actives
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A silicone that mixes with water creating nice light-weight product texture
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a gel-like product texture, as well as to stabilize emulsions
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Tea extract. Might be helpful in neutralizing free radicals in skin
Potential irritants
Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Helps water and oil mix together and has an anti-microbial effect helping to preserve product formulations
Can work as an exfoliant but is typically used to adjust the product pH
Helps preserve products and creates a nice product texture
Used to preserve products, dissolve other ingredients and create a nice product texture
Helps preserve products and creates a nice product texture
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
Help soften the upper layer of the skin and make it easier for oil and water mix together. Recently, a rising number of allergic reactions to cocoglycerides and other coconut-derived surfactants has been reported. As there is a significant overlap between frequent irritants and allergens, we flag this ingredient for attention of those with very sensitive, reactive skin
A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Lecithin derivative. It helps oil and water mix together and can enhance penetration of other ingredients. It helps soften the upper layer of the skin
Two steps removed from the active form of vitamin A - retinoic acid. Once converted to the retinoic acid in the skin, retinol is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. It can, however, be quite irritating
Helps water and oil mix together and has an anti-microbial effect helping to preserve product formulations
Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect
Can work as an exfoliant but is typically used to adjust the product pH
Helps preserve products and creates a nice product texture
A preservative. It helps prevent bacterial growth in cosmetic products
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A silicone that helps improve the product texture and spreadability. Can absorb oil creating a short-term mattifying effect on the skin
Used to preserve products, dissolve other ingredients and create a nice product texture
Used to create a thicker product texture. Helps soften the upper layer of the skin and might be able to prevent moisture loss from its surface
Used to stabilize product formulations and create a nice product texture
Used to create a gel-like product texture, as well as to stabilize emulsions
A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish
A silicone that mixes with water creating nice light-weight product texture
A silicone that makes products more spreadable and keeps skin smooth. Helps to add gloss to skin and may visually fill in fine lines/wrinkles for short time
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Tea extract. Might be helpful in neutralizing free radicals in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Might help to reduce inflammation in skin, but solid research is lacking
An active component of chamomile plant that historically has been used to calm down irritated skin. A recent study shows that bisabolol indeed can have some anti-inflammatory effect on skin, even though conclusive data is lacking. Bisabolol has a sweet floral scent and can be added to products for its aromatic properties
A plant extract that can contain an irritating essential oil. Might have some anti-oxidant effect, but evidence is lacking
Helps preserve products and creates a nice product texture
A preservative. It helps prevent bacterial growth in cosmetic products
Ingredient list view
Water, Cocoglycerides, Carthamus tinctorius extract, Unknown, Tocopheryl acetate, Acrylates/c10-30 alkyl acrylate crosspolymer, Sodium hyaluronate, Lysolecithin, Retinol, Glyceryl diretinoate, Glyceryl laurate, Retinyl palmitate, Citric acid, Bht, Acetyl carboxymethyl cocoyl glycine, Carthamus tinctorius extract, Unknown, Caprylyl glycol, Phenoxyethanol, Water, Glycerin, Butylene glycol, Cyclopentasiloxane, Pentylene glycol, Peg-12 dimethicone crosspolymer, Dimethicone crosspolymer, Dimethicone/vinyl dimethicone crosspolymer, Sodium polyacrylate, Dimethicone, Peg/ppg-18/18 dimethicone, Dimethiconol, Sodium hyaluronate, Camellia sinensis extract, Disodium edta-copper, Myristoyl pentapeptide-17, Hydroxyphenyl propamidobenzoic acid, Bisabolol, Zingiber officinale root extract, Polysorbate 60, Caprylyl glycol, Phenoxyethanol
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety
- Improvement of naturally aged skin with vitamin A (retinol)
- A comparative study of the effects of retinol and retinoic acid on histological, molecular, and clinical properties of human skin
- Glycerol and the skin: holistic approach to its origin and functions
- Dimethicone as a protective ingredient in topical medications
- Final Report on the Safety Assessment of Dimethicone Copolyol
- α-(-)-Bisabolol Reduces Pro-Inflammatory Cytokine Production and Ameliorates Skin Inflammation
- Some phytochemical, pharmacological and toxicological properties of ginger (Zingiber officinale Roscoe): A review of recent research