Works for:
based on ingredients and %- Anti-aging
- Moisturizing
- Evens skin tone
- Exfoliation
Can it cause trouble?
- Irritation risk: medium
- Comedogenic risk ingredients: 0
Key actives
Product Summary
"Aizen Dermatology - Pythocrystal Holybright Ampoule" is effective for: Exfoliation, Anti-aging, Moisturizing and Evens skin tone
Ingredient callouts
- This product contains acids (lactobionic acid 0.55% - 1.35%). Their concentration is low, and they will not have a strong exfoliating effect. Instead, they work to support the skin natural acid mantle and to attract water (as humectants). PHAs (lactobionic acid) especially are great for improving skin hydration. They might be even able to stimulate the production of skin's natural humectants and support the healthy skin microbiome.
- Peptides (nonapeptide-1 0.10% - 0.35%, tetrapeptide-30 0.05% - 0.30% and hexapeptide-2 1.60% - 2.40%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
- Humectants (glycerin 3.80% - 5.80%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains lactobionic acid.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: aminopropyl ascorbyl phosphate, hexapeptide-2, nonapeptide-1, tetrapeptide-30.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Anti-oxidation
This product contains antioxidants (dimethylmethoxy chromanol, ethylbisiminomethylguaiacol manganese chloride, glutathione, lactobionic acid, superoxide dismutase) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
The following ingredients - aminopropyl ascorbyl phosphate, hexylresorcinol, tetrahydrodiferuloylmethane also can have an antioxidant effect, but there is less evidence to confirm their effectiveness in skin.
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
Can help neutralize free radicals in skin
A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: alpha-arbutin, glutathione, lactobionic acid, tranexamic acid, undecylenoyl phenylalanine
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: aminopropyl ascorbyl phosphate, hexylresorcinol, phenylethyl resorcinol, tetrahydrodiferuloylmethane.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
An amino-acid based compound that is effective in reducing hyperpigmentation. It can help lighten sun spots and support more even skin tone.
Might help reduce hyperpigmentation in skin and help neutralize free radicals
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Exfoliation
This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: lactobionic acid.
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
An enzyme extracted from papaya fruit. Can have an exfoliating effect on the skin. Can be irritating
Moisturizing
This product contains good ingredients to attract water to the upper layer of the skin. These ingredients are called "humectants": glycerin.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. If the air is dry, humectants can speed up the moisture loss from the skin. This is why it is a good idea to use another product on top of this one to help "seal in" the moisture (look for ingredients like dimethicone, squalane, oils and butters).
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: hexapeptide-2, lactobionic acid, nonapeptide-1, tetrapeptide-30
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Anti-aging | |
| Moisturizing | |
| Evens skin tone |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
No comedogenic ingredients detected
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Key Actives
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications
An amino-acid based compound that is effective in reducing hyperpigmentation. It can help lighten sun spots and support more even skin tone.
Can help neutralize free radicals in skin
Might help reduce hyperpigmentation in skin and help neutralize free radicals
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
Potential irritants
An amino-acid based compound that is effective in reducing hyperpigmentation. It can help lighten sun spots and support more even skin tone.
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
An enzyme extracted from papaya fruit. Can have an exfoliating effect on the skin. Can be irritating
Might help reduce hyperpigmentation in skin and help neutralize free radicals
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Can work as an exfoliant but is typically used to adjust the product pH
Comedogenic ingredients
We couldn't find any comedogenic ingredients in this product
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Might help reduce hyperpigmentation when used regularly over a long period of time. Is more effective than beta-arbutin
Might be helpful in reducing hyperpigmentation and neutralizing free radicals in skin
A more stable but less potent derivative of vitamin C. It can help neautralize free radicals and even out the skin tone if used in high enough concentration (required levels are likely to be much higher than for pure vitamin C, and solid studies are lacking at the moment)
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
Being a lipid soluble form of vitamin C, it is more stable than ascorbic acid, but still degrades quickly and needs to be stabilized in a formulation with another ingredient. It is claimed to penetrate skin better than pure vitamin C and have the the similar benefits, but solid studies of its effectiveness are lacking. Is likely to require a higher concentration in a product than pure vitamin C to be effective. It might be able to help reduce pore clogging.
An antioxidant enzyme that is naturally present in skin. It can help support skin barrier function and reduce inflammation in skin. It is used in topical medications for inflammatory skin conditions including atopic dermatitis (eczema) and psoriasis. There are three types of natural Superoxide Dismutase in human skin. The compound used in topical treatments and cosmetics are mimics of typically one of these natural variants
A potent anti-oxidant that can help neutralize free radicals in skin and protect from harmful effects of sun exposure, even though more studies are needed to confirm its effectiveness in topical applications
A polyhydroxy acid (PHA) that helps shed dead cells from the surface of the skin revealing a smoother, more even skin. PHAs tend to be gentler on the skin compared to AHAs (for example, glycolic acid). It also has hydrating properties and helps attract water to the upper layer of the skin. It can help calm down inflammation in skin and support restoration of the barrier function. It has an anti-oxidant effect as well. It can help reduce fine line, wrinkles and improve skin elasticity
An amino-acid based compound that is effective in reducing hyperpigmentation. It can help lighten sun spots and support more even skin tone.
An anti-oxidant derived from curcumin (naturally present in tumeric). Is a part of the tetrahydrocurcuminoids complex (THC). The complex might be helpful in neutralizing free radicals in skin and possibly help even out the skin tone. Can be irritating
A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin
Maintains the texture of skincare products. Allows the product to spread evenly. Helps oil and water mix together
Can work as an exfoliant but is typically used to adjust the product pH
An enzyme extracted from papaya fruit. Can have an exfoliating effect on the skin. Can be irritating
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help reduce hyperpigmentation in skin and help neutralize free radicals
A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening
A derivative of azelaic acid. It is obtained by reacting the chloride of azelaic acid with two molecules of glycine (an amino acid) and potassium hydroxide. It is less studied than azelaic acid, but the available research suggests that it also can be effective in reducing skin redness, hyperpigmentation and blemishes. There are claims that it is more bio-available and more effective than azelaic acid, but no comparison study is available. Potassium azeloyl diglycinate is better soluble in water compared with azelaic acid. Because of this property, products with potassium azeloyl digclycinate can have a nicer texture
Helps oil and water mix together. Might help suppress growth of acne-triggering bacteria in skin
A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles
An amino acid that is effective in reducing hyperpigmentation and evening out the skin tone. It can also help in skin barrier recovery. It is used to treat melasma, especially with injections and when taken orally
A type of sugar that is used to support delivery of active ingredients and can enhance their penetration into the skin without disrupting the skin's barrier
Helps attract water to the upper layer of the skin. Can have some anti-inflammatory effect
Ingredient list view
Water, Glycerin, Alpha-arbutin, Hexylresorcinol, Aminopropyl ascorbyl phosphate, Hexapeptide-2, Tetrahexyldecyl ascorbate, Superoxide dismutase, Ethylbisiminomethylguaiacol manganese chloride, Lactobionic acid, Undecylenoyl phenylalanine, Tetrahydrodiferuloylmethane, Glutathione, Acrylates/c10-30 alkyl acrylate crosspolymer, Dimethylmethoxy chromanol, Citric acid, Polyglyceryl-3 cetyl ether, 4-butylresorcinol, Papain, Niacinamide, Oxothiazolidinecarboxylic acid, Phenylethyl resorcinol, Paeonia suffruticosa root extract, Xanthan gum, Decapeptide-12, Tetrapeptide-30, Dipotassium glycyrrhizate, Potassium azeloyl diglycinate, Octadecenedioic acid, Nonapeptide-1, Succinic acid, Tranexamic acid, Hydroxyacetophenone, Cyclodextrin, Saccharomyces lysate extract, Sodium sulfite
- Glycerol and the skin: holistic approach to its origin and functions
- An exemplary claim substantiation for the firming / filling activity of a synthetic tripeptide
- Double-blind, half-face study comparing topical vitamin C and vehicle for rejuvenation of photodamage
- Application of tetra-isopalmitoyl ascorbic acid in cosmetic formulations: Stability studies and in vivo efficacy
- A novel efficient and safe treatment for atopic dermatitis: Topical superoxide dismutase (SOD).
- Novel topical agent containing superoxide dismutase 100 000 IU and 4% of plant extracts as a mono-therapy for atopic dermatitis
- Copper/Zinc Superoxide Dismutase in Human Skin: Current Knowledge
- Photoprotective Effect of Topically Applied Superoxide Dismutase on Sunburn Reaction in Comparison with Sunscreen
- The role of superoxide dismutase (SOD) in skin disorders
- Topical formulations with superoxide dismutase: Influence of formulation composition on physical stability and enzymatic activity
- Skin protective effects of RM191A, a novel superoxide dismutase mimetic
- A Synthetic Superoxide Dismutase/Catalase Mimetic (EUK-134) Inhibits Membrane-Damage-Induced Activation of Mitogen-Activated Protein Kinase Pathways and Reduces p53 Accumulation in Ultraviolet B-Exposed Primary Human Keratinocytes
- Use of the synthetic superoxide dismutase/catalase mimetic EUK-134 to compensate for seasonal antioxidant deficiency by reducing pre-existing lipid peroxides at the human skin surface
- A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin
- Lactobionic acid
- Effects of lactobionic acid peel, aluminum oxide crystal microdermabrasion, and both procedures on skin hydration, elasticity, and transepidermal water loss
- Comparative evaluation of skin moisture after topical application of 10% and 30% lactobionic acid
- The use of polyhydroxy acids (PHAs) in photoaged skin
- A randomized, double‐blind, vehicle‐controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines
- Use of tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa
- Tetrahydrocurcuminoid cream plus targeted narrowband UVB phototherapy for vitiligo: a preliminary randomized controlled study
- Skin lightening effect of tetrahydrocurcumin
- Glutathione as a skin whitening agent: Facts, myths, evidence and controversies
- Glutathione for skin lightening: a regnant myth or evidence-based verity?
- Glutathione for skin lightening for dermatologists and cosmetologists
- Singlet molecular oxygen quenching by the antioxidant dimethylmethoxy chromanol in solution and in ex vivo porcine skin
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- Ameliorating effect of dipotassium glycyrrhizinate on an IL-4- and IL-13-induced atopic dermatitis-like skin-equivalent model
- Final report on the safety assessment of Glycyrrhetinic Acid, Potassium Glycyrrhetinate, Disodium Succinoyl Glycyrrhetinate, Glyceryl Glycyrrhetinate, Glycyrrhetinyl Stearate, Stearyl Glycyrrhetinate, Glycyrrhizic Acid, Ammonium Glycyrrhizate, Dipotassium Glycyrrhizate, Disodium Glycyrrhizate, Trisodium Glycyrrhizate, Methyl Glycyrrhizate, and Potassium Glycyrrhizinate.
- Clinical and instrumental assessment of the effects of a new product based on hydroxypropyl chitosan and potassium azeloyl diglycinate in the management of rosacea
- A Preliminary Clinical Evaluation of a Topical Product for Reducing Slight Rosacea Imperfections
- Azeloyl-Glycine: A new active in skin disequilibrium
- Formulation and evaluation of the cream made from potassium azeloyl diglycinate as an anti-aging
- Effect of tranexamic acid on melasma: a clinical trial with histological evaluation
- Tranexamic acid accelerates skin barrier recovery and upregulates occludin in damaged skin
- The amelioration effect of tranexamic acid in wrinkles induced by skin dryness
- Efficacy and possible mechanisms of topical tranexamic acid in melasma
- Cyclodextrins: new drug delivery systems in dermatology
- Use of Probiotics for Dermal Applications