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Advanced MD Hyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin - Professional Formula To Restore Moisture, Reduce Fine Lines, & Instantly Improve Skin - 100% Clean Beauty
Advanced MD

Advanced MD Hyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin - Professional Formula To Restore Moisture, Reduce Fine Lines, & Instantly Improve Skin - 100% Clean Beauty

Efficacy62/100IrritancyHigh
See all ingredients

Works for

Moisturizing
Glycerin, Pyrus malus fruit extract + 7 more
Works
What the product description says
“Hyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin .”
From product name

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: chondrus crispus extract, dimethicone.

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.2–5.2%
Pyrus malus fruit extractKey activeEffect: MediumCan have some moisturizing properties due to its sugar content~3.2–3.9%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2.5–3.1%
Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~2–2.4%
Chondrus crispus extractKey active· OcclusiveEffect: HighRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency~1.7–2.1%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.4–1.8%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.4–0.6%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.2–1.4%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.05–0.1%
Anti-aging
Camellia sinensis leaf extract, Aloe barbadensis leaf juice + 1 more
Not delivered
What the product description says
“Hyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin .”
From product name

This product does not contain ingredients that are able to reduce fine lines and wrinkles or help with skin elasticity, but it can improve the look of the skin temporarily through moisturization. Well-moisturized skin might also be able to repair the sun damage better.This ingredient - camellia sinensis leaf extract - could be helpful for preventing or repairing signs of aging in theory, but there is no evidence that it actually works.

This ingredient camellia sinensis leaf extract might be able to help neutralize free radicals in skin and help it fight off some of the sun damage.

Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.4–1.8%
Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~1.2–1.4%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.05–0.1%
Anti-oxidation
Side benefit · Camellia sinensis leaf extract, Epilobium angustifolium flower/leaf/stem extract + 3 more
May help

This product contains antioxidants (camellia sinensis leaf extract, epilobium angustifolium flower/leaf/stem extract) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Camellia sinensis leaf extractKey activeEffect: MediumCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~1.4–1.8%
Epilobium angustifolium flower/leaf/stem extractKey activeEffect: MediumA plant extract that might contain antioxidants~0.65–1%
Pyrus malus fruit extractEffect: LowCan have some moisturizing properties due to its sugar content~3.2–3.9%
Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.55–0.85%
GluconolactoneUnder-dosedA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals~0.05–0.1%

Can it cause trouble?

Irritancy
5 strong irritants: Parfum, Limonene + 3 more — patch-test recommended
High risk
We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Epilobium angustifolium flower/leaf/stem extractA plant extract that might contain antioxidantsHigh~0.65–1%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.45–0.65%est.
LimoneneA common frangrance that can easily irritate skin, especially if exposed to air, light or heatHigh~0.2–0.4%est.
GeraniolA fragrance. Can be irritatingHigh~0.2–0.35%est.
Hexyl cinnamalA fragrance with jasmine smell. A likely irritantHigh~0.15–0.3%est.
LinaloolA fragrance. Can be irritatingHigh~0.15–0.25%est.
EthoxydiglycolHelps to improve the product consistencyMedium~6.3–7.7%est.
Pyrus malus fruit extractCan have some moisturizing properties due to its sugar contentMedium~3.2–3.9%est.
Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~1.2–1.4%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.55–0.85%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.4–0.6%est.
EthylhexylglycerinA preservativeMedium~0.3–0.55%est.
Hexylene glycolHelps create a more spreadable product textureMedium~0.25–0.45%est.
Citric acidCan work as an exfoliant but is typically used to adjust the product pHMedium~0.25–0.45%est.
Sodium metabisulfiteA preservativeMedium~0.1–0.2%est.
GluconolactoneA polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicalsMedium~0.05–0.1%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Chondrus crispus extractRed algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency3/5~1.7–2.1%est.
Alternatives
The closest match we found
Hyaluronic Serum
ADVANCED CLINICALS Hyaluronic Serum
Closest match50% match
$12.99
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Ethoxydiglycol~6.3–7.7%
Irritant · medium
Irritation risk
Medium

Helps to improve the product consistency

More about Ethoxydiglycol
Glycerin~4.2–5.2%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Pyrus malus fruit extract~3.2–3.9%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidation

Can have some moisturizing properties due to its sugar content

More about Pyrus malus fruit extract
Dimethicone~2.5–3.1%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Sodium hyaluronate~2–2.4%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate
Chondrus crispus extract~1.7–2.1%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

Red algae extract that helps attract water to the upper layer of the skin and create a nicer product consistency

More about Chondrus crispus extract
Camellia sinensis leaf extract~1.4–1.8%
Key active
Irritation risk
Low
Works for
AntibacterialAnti-oxidationAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Aloe barbadensis leaf juice~1.2–1.4%
Irritant · medium
Irritation risk
Medium
Works for
MoisturizingAntibacterialReduces irritationReduces rednessAnti-inflammatoryAnti-blemishAnti-aging

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice
Sodium carboxymethyl beta-glucan~1.3–1.6%
Formula
Irritation risk
Low

Helps thicken the product formulation and create a gel-like texture

More about Sodium carboxymethyl beta-glucan
Epilobium angustifolium flower/leaf/stem extract~0.65–1%
Key activeIrritant · high
Irritation risk
High
Works for
Anti-oxidation

A plant extract that might contain antioxidants

More about Epilobium angustifolium flower/leaf/stem extract
Tocopheryl acetate~0.55–0.85%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Xanthan gum~0.5–0.75%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Parfum~0.45–0.65%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Phenoxyethanol~0.45–0.65%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Maltodextrin~0.45–0.65%
Formula
Irritation risk
Low
Works for
Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin
Tetrasodium glutamate diacetate~0.35–0.65%
Formula
Irritation risk
Low

Helps stabilize the product formulation

More about Tetrasodium glutamate diacetate
Caprylyl glycol~0.4–0.6%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ethylhexylglycerin~0.3–0.55%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Hexylene glycol~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps create a more spreadable product texture

More about Hexylene glycol
Citric acid~0.25–0.45%
Irritant · medium
Irritation risk
Medium

Can work as an exfoliant but is typically used to adjust the product pH

More about Citric acid
Limonene~0.2–0.4%
Irritant · high
Irritation risk
High

A common frangrance that can easily irritate skin, especially if exposed to air, light or heat

More about Limonene
Geraniol~0.2–0.35%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Geraniol
Hexyl cinnamal~0.15–0.3%
Irritant · high
Irritation risk
High

A fragrance with jasmine smell. A likely irritant

More about Hexyl cinnamal
Linalool~0.15–0.25%
Irritant · high
Irritation risk
High

A fragrance. Can be irritating

More about Linalool
Sodium hydroxide~0.15–0.25%
Formula
Irritation risk
Low

Used to adjust the product's pH

More about Sodium hydroxide
Sodium metabisulfite~0.1–0.2%
Irritant · medium
Irritation risk
Medium

A preservative

More about Sodium metabisulfite
Gluconolactone~0.05–0.1%
Under-dosedIrritant · medium
Irritation risk
Medium
Works for
ExfoliationMoisturizingAnti-agingEvens skin toneAnti-oxidationAnti-blemish

A polyhydroxy acid (PHA) that helps shed the dead cells from the skin surface revealing smoother skin. Is believed to be genter than AHAs. It helps attract water to the upper layer of the skin and can stimulate production of skin's own hyaluronic acid resulting in improved hydration levels. It has been shown to be helpful against acne and clogged pores if used consistently (e.g over a period of 12 weeks) in high enough concentration. It can help reduce fine lines and wrinkles and improve skin tone with long-term application. Can help neutralize free radicals

More about Gluconolactone
Sodium benzoate~0.1–0.15%
Formula
Irritation risk
Low

A preservative

More about Sodium benzoate
Ingredient list view

Water, Ethoxydiglycol, Glycerin, Pyrus malus fruit extract, Dimethicone, Sodium hyaluronate, Chondrus crispus extract, Camellia sinensis leaf extract, Aloe barbadensis leaf juice, Sodium carboxymethyl beta-glucan, Epilobium angustifolium flower/leaf/stem extract, Tocopheryl acetate, Xanthan gum, Parfum, Phenoxyethanol, Maltodextrin, Tetrasodium glutamate diacetate, Caprylyl glycol, Ethylhexylglycerin, Hexylene glycol, Citric acid, Limonene, Geraniol, Hexyl cinnamal, Linalool, Sodium hydroxide, Sodium metabisulfite, Gluconolactone, Sodium benzoate

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
Advanced MDHyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin - Professional Formula To Restore Moisture, Reduce Fine Lines, & Instantly Improve Skin - 100% Clean BeautyYOUR PRODUCTADVANCED CLINICALSHyaluronic SerumHempzCBD Balancing Act Hydrating Facial SerumNeutrogenaHydro Boost Hydrating Serum
Match—50%38%38%
Price—$12.99—$13.09
Shared key ingredients—5 of 64 of 64 of 6
Key difference——CbdBisabolol
Irritancy High Medium Medium Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 19 studies and safety reviews.

  1. 1
    Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
  2. 2
    Dimethicone as a protective ingredient in topical medicationsjaad.org
  3. 3
    Final Report on the Safety Assessment of Dimethicone Copolyoljournals.sagepub.com
  4. 4
    Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
  5. 5
    Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
  6. 6
    Therapeutic Potential of Polyphenols from Epilobium Angustifolium (Fireweed): Polyphenols from Fireweedresearchgate.net
Advanced MD Hyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin - Professional Formula To Restore Moisture, Reduce Fine Lines, & Instantly Improve Skin - 100% Clean Beauty
Advanced MDHyaluronic Acid Face Serum Skin Care For Wrinkles & Dry Skin - Professional Formula To Restore Moisture, Reduce Fine Lines, & Instantly Improve Skin - 100% Clean Beauty
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Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Find on Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.