Retinal

Appears on 1 avoid lists

Included in 22 routines

Summary

Works for
  • Evens skin tone
  • Anti-blemish
  • Anti-aging
Irritancy risk
HIGH
WIMJ Team

One step removed from the biologically active in skin form of vitamin A. Once converted to the retinoic acid in the skin, retinal is proven to be effective against all signs of aging. It improves skin cell turnover, helps fight blemishes and clogged pores, can regulate excess oil production and even skin tone. Concentrations of 0.05% and 0.1% are shown to be effective. It can, however, be irritating

Products with Retinal

ByWishtrend - Vitamin A-mazing Bakuchiol Body Lotion ByWishtrend Vitamin A-mazing Bakuchiol Body Lotion
Works for:
  • Anti-aging
  • Moisturizing
  • Anti-blemish
Irritancy risk:
Key ingredients:
  • niacinamide
  • salicylic acid
  • retinal
K-SECRET - SEOUL 1988 Serum : Retinal Liposome 2% + Black Ginseng K-SECRET SEOUL 1988 Serum : Retinal Liposome 2% + Black Ginseng
Works for:
  • Anti-aging
  • Anti-oxidation
  • Moisturizing
Irritancy risk:
Key ingredients:
  • niacinamide
  • retinal
  • adenosine
Murad - Retinal ReSculpt™ Eye Lift Treatment Murad Retinal ReSculpt™ Eye Lift Treatment
Works for:
  • Anti-aging
  • Moisturizing
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • retinal
  • Oatmeal extract
  • urea
esfolio - Eye Cream Retinol Vital esfolio Eye Cream Retinol Vital
Works for:
  • Anti-aging
  • Moisturizing
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • niacinamide
  • retinal
  • retinol
Cipher Skincare - 88MPH Cipher Skincare 88MPH
Works for:
  • Anti-blemish
  • Anti-aging
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • salicylic acid
  • madecassoside
  • retinal
Avène - A-Oxitive EYES Smoothing Eye Contour Cream - Vitamin A eye cream Avène A-Oxitive EYES Smoothing Eye Contour Cream - Vitamin A eye cream
Works for:
  • Anti-aging
  • Moisturizing
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • oleoyl dipeptide-15
  • oleoyl tetrapeptide-31
  • Mineral oil
Skincare by Dr. V. - HPC CLEAR Cream Skincare by Dr. V. HPC CLEAR Cream
Works for:
  • Evens skin tone
  • Anti-oxidation
  • Anti-aging
Irritancy risk:
Key ingredients:
  • retinol
  • retinal
  • salicylic acid
Matkas - Retinal 0.05% Capsule Hybrid Cream Matkas Retinal 0.05% Capsule Hybrid Cream
Works for:
  • Anti-aging
  • Moisturizing
  • Anti-blemish
Irritancy risk:
Key ingredients:
  • niacinamide
  • retinal
  • adenosine
Raaie - Yellow Moonbeam Retinal Elixir Raaie Yellow Moonbeam Retinal Elixir
Works for:
  • Anti-aging
  • Evens skin tone
  • Anti-blemish
Irritancy risk:
Key ingredients:
  • niacinamide
  • retinal
  • anhydroxylitol
CKD Guaranteed - Retino Collagen Small Molecule 300 Intensive Cream CKD Guaranteed Retino Collagen Small Molecule 300 Intensive Cream
Works for:
  • Anti-aging
  • Moisturizing
  • Evens skin tone
Irritancy risk:
Key ingredients:
  • niacinamide
  • nonapeptide-1
  • retinal
View all

Questions

Clinical trials review

Number of participants Participants Interventions Punchline
40 40 healthy Korean female volunteers >30 years old. The exclusion criteria were facial dermatosis, a known allergy to any cosmetic ingredient, and prior use of topical or systemic retinoids or steroids. Either the RAL 0.1% or RAL 0.05% cream was applied twice daily. The study duration was 12 weeks and included four assessment visits: an inclusion visit in week 0 (baseline), and three further visits at 4, 8, and 12 weeks The 3-month application improved overall photoaging in both RAL 0.1% (95%) and RAL 0.05% groups (95%). Both RAL 0.1% and RAL 0.05% afforded significant textural improvements (13.7% and 12.6%, respectively), reduced the TEWL (14.5%, 17.9%), and increased hydration (10.2%, 6.0%); however, no statistical differences were observed between two groups. Only RAL 0.1% significantly improved the melanin index (by 6.5%)

Efficacy and safety of retinaldehyde 0.1% and 0.05% creams used to treat photoaged skin: A randomized double-blind controlled trial

Number of participants Participants Interventions Punchline
40 Women over 35 years of age, with moderate to severe photodamage Patients applied either retinaldehyde 0.05% on their faces once daily for 1 year, or were left untreated (emollient only, control group). Compared to the control group, retinaldehyde treatment induced a significant increase in epidermal thickness of the temple, as well as in cutaneous elasticity (p < 0.01). Similarly, retinaldehyde treatment tended to increase dermal thickness and reduce cutaneous stiffness, but no statistical difference could be observed between the two groups.

Efficacy of topical 0.05% retinaldehyde in skin aging by ultrasound and rheological techniques

Number of participants Participants Interventions Punchline
55 Subjects included were female volunteers (age 35-55 years) with skin phototype I-III according to Fitzpatrick classification with at least 1 deep, long (≥1 cm) wrinkle on the flat part of the crow’s feet area, and the presence of periorbicular fine lines and wrinkles. Facial hygiene regimens had to be kept unchanged and be well tolerated for at least 4 weeks before inclusion Participants were randomized in 2 treatment groups: (1) Daily application of the antiaging cream for 8 weeks or (2) Three sequential GA peels (20%, 50%, and 70%), 2-3 weeks apart. : Efficacy of both treatments was similar in reducing crow’s feet wrinkles depth (STm 7.61%, P = .0007 vs 4.34%, P = .0348; P = .3049 intergroup) and volume, crow’s feet and periorbital wrinkle length, and number of fine lines and wrinkles at end of treatments. The efficacy of the cream in refining skin texture was superior to the peels (contrast: 5.61%, P = .0025 vs +3.54, P = .08; P intergroup = .0252). The 8-week treatment with the antiaging cream was well tolerated; adverse events were fewer and of milder intensity than with the peels, (12-fold lower incidence of physical signs).

Antiaging efficacy of a retinaldehyde-based cream compared with glycolic acid peel sessions: A randomized controlled study

Scientifc sources

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