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VENN Skincare Synbiotic Defense Mist
VENN Skincare

VENN Skincare Synbiotic Defense Mist

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Moisturizing
Niacinamide, Panthenol + 12 more
Works well
What the product description says
“Specifically formulated not to quickly evaporate or vanish from the skin, the formulation is clinically tested to keep the skin hydrated for 24 hours.”
Source: Venn

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: arginine, galactomyces ferment filtrate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: arginine, caprylyl glycol.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: niacinamide, panthenol

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.8–1.25%
PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.35–0.8%
Saccharomyces fermentKey activeEffect: HighA product of yeast fermentation. Helps attract water to the upper layer of the skin~25–38%
Galactomyces ferment filtrateKey active· HumectantEffect: HighA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~5.2–7.8%
Lactobacillus fermentKey active· HumectantEffect: HighA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~4.1–6.1%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~1.3–1.9%
Bacillus fermentKey activeEffect: HighA product of bacterial fermentation. Can help attract water to the upper layer of the skin~0.45–1%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.2–0.75%
AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%
ArginineKey active· Humectant, OcclusiveEffect: HighAn amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin~0.05–0.25%
Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~1.6–2.4%
Caprylyl glycol· Humectant, EmollientEffect: LowHelps preserve products and creates a nice product texture~0.1–0.3%
Scutellaria baicalensis root extract· HumectantEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.05–0.15%
Dipotassium glycyrrhizateUnder-dosedA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.55%
Anti-blemish
Side benefit · Niacinamide, Galactomyces ferment filtrate
Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.8–1.25%
Galactomyces ferment filtrateEffect: LowA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~5.2–7.8%
Evens skin tone
Side benefit · Galactomyces ferment filtrate, Niacinamide + 2 more
Works well

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: glutathione, niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: galactomyces ferment filtrate.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Galactomyces ferment filtrateKey activeEffect: MediumA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~5.2–7.8%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.8–1.25%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.2–0.75%
Dipotassium glycyrrhizateEffect: Low, below effective doseA salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening~0.15–0.55%
Anti-oxidation
Side benefit · Galactomyces ferment filtrate, Camellia sinensis catechins + 6 more
Works well

This product contains antioxidants (camellia sinensis catechins, galactomyces ferment filtrate, glutathione) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

Galactomyces ferment filtrateKey activeEffect: HighA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~5.2–7.8%
Camellia sinensis catechinsKey activeEffect: HighA group of chemical compounds extracted from Green Tea. They can help neutralize free radicals in skin. Might be able to help repair sun damage and clam down inflammation in skin~0.3–0.75%
GlutathioneKey activeEffect: HighA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin~0.2–0.75%
Lactobacillus fermentEffect: LowA fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative~4.1–6.1%
Camellia sinensis leaf waterEffect: LowGreen tea leaf water. Might have some minimal anti-oxidant effect~2.1–3.2%
AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%
Scutellaria baicalensis root extractEffect: LowA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties~0.05–0.15%
Paeonia suffruticosa root extractEffect: Low~0.05–0.2%
Anti-aging
Side benefit · Galactomyces ferment filtrate, Niacinamide + 2 more
Works well

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: camellia sinensis catechins, galactomyces ferment filtrate.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

Galactomyces ferment filtrateKey activeEffect: MediumA yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores~5.2–7.8%
NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~0.8–1.25%
Camellia sinensis catechinsKey activeEffect: MediumA group of chemical compounds extracted from Green Tea. They can help neutralize free radicals in skin. Might be able to help repair sun damage and clam down inflammation in skin~0.3–0.75%
AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.15–0.55%

Can it cause trouble?

Irritancy
1 strong irritant: Eucalyptus globulus leaf oil
Medium risk
We flagged 7 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
PullulanCreates a thin drying film on the skin resulting in a short-term tightening effectHigh~0.35–0.8%est.
Eucalyptus globulus leaf oilAn essential oil that can be very irritating. Has some anti-bacterial propertiesHigh~0.1–0.4%est.
Paeonia suffruticosa root extract—High~0.05–0.2%est.
Scutellaria baicalensis root extractA plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant propertiesHigh~0.05–0.15%est.
1,2-hexanediolA preservativeMedium~0.35–0.85%est.
GlutathioneA peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skinMedium~0.2–0.75%est.
Caprylyl glycolHelps preserve products and creates a nice product textureMedium~0.1–0.3%est.
Comedogenic
Clean of flagged comedogenic ingredients
None flagged
Alternatives
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Galac Niacin 3.0 Essence
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Ingredients

Filter by role to see what each ingredient is doing.

Saccharomyces ferment~25–38%
Key active
Irritation risk
Low
Works for
Moisturizing

A product of yeast fermentation. Helps attract water to the upper layer of the skin

More about Saccharomyces ferment
Galactomyces ferment filtrate~5.2–7.8%
Key active
Irritation risk
Low
Works for
Anti-oxidationMoisturizingEvens skin toneAnti-agingMattifyingAnti-blemish

A yeast ferment filtrate (also known as Pitera - a trademarked name for the filtrate reserved by the SK-II brand). It helps attract water to the upper layer of the skin, can help neutralize antioxidants and can be helpful in evening out the skin tone. It might be somewhat helpful in preventing premature skin aging but solid evidence is lacking. A small manufacturer study also shows that, when used in high concentrations, it can help reduce sebum production and help against blocked pores

More about Galactomyces ferment filtrate
Lactobacillus ferment~4.1–6.1%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryAnti-oxidationReduces irritation

A fermentation product created by bacteria Lactobacillus. The fermented product has anti-bacterial properties and might be helpful in calming down inflammation, but studies are lacking. Helps attract water to the upper layer of the skin. Can be used as a preservative

More about Lactobacillus ferment
Water~3.2–4.8%
Formula
Irritation risk
Low

Plain old water

More about Water
Camellia sinensis leaf water~2.1–3.2%
Formula
Irritation risk
Low
Works for
Anti-oxidation

Green tea leaf water. Might have some minimal anti-oxidant effect

More about Camellia sinensis leaf water
Butylene glycol~1.6–2.4%
Formula
Irritation risk
Low
Works for
Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol
Glycerin~1.3–1.9%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
1,2-hexanediol~0.35–0.85%
Irritant · medium
Irritation risk
Medium

A preservative

More about 1,2-hexanediol
Niacinamide~0.8–1.25%
Hero · Moisturizing, Anti-blemish
Irritation risk
Low
Works for
Evens skin toneAnti-agingMoisturizingAnti-blemishReduces irritationReduces rednessAntibacterialAnti-inflammatory

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide
Levan~0.8–1.2%
Formula
Irritation risk
Low
More about Levan
Bacillus ferment~0.45–1%
Key active
Irritation risk
Low
Works for
Moisturizing

A product of bacterial fermentation. Can help attract water to the upper layer of the skin

More about Bacillus ferment
Camellia sinensis catechins~0.3–0.75%
Key active
Irritation risk
Low
Works for
Anti-oxidationReduces rednessAnti-inflammatoryAnti-agingReduces irritation

A group of chemical compounds extracted from Green Tea. They can help neutralize free radicals in skin. Might be able to help repair sun damage and clam down inflammation in skin

More about Camellia sinensis catechins
Panthenol~0.35–0.8%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingReduces rednessReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol
Glutathione~0.2–0.75%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-oxidationEvens skin tone

A peptide that can help neutralize free radicals in skin and reduce melanin production resulting in skin lightening effect and reduction in hyperpigmentation. It can also help attract moisture to the upper layer of the skin

More about Glutathione
Pullulan~0.35–0.8%
Irritant · high
Irritation risk
High
Works for
Mattifying

Creates a thin drying film on the skin resulting in a short-term tightening effect

More about Pullulan
Adenosine~0.15–0.55%
Key active
Irritation risk
Low
Works for
Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine
Dipotassium glycyrrhizate~0.15–0.55%
Under-dosed
Irritation risk
Low
Works for
MoisturizingAnti-inflammatoryEvens skin tone

A salt derived from licorice. Works as an emollient to soften the upper layer of the skin and can help calm down inflammation. Might be helpful for skin lightening

More about Dipotassium glycyrrhizate
Eucalyptus globulus leaf oil~0.1–0.4%
Irritant · high
Irritation risk
High
Works for
Antibacterial

An essential oil that can be very irritating. Has some anti-bacterial properties

More about Eucalyptus globulus leaf oil
Arginine~0.05–0.25%
Key active
Irritation risk
Low
Works for
Moisturizing

An amino acid that is naturally present in skin and helps keep it hydrated. When used together with AHAs, it can reduce their irritating effect on the skin

More about Arginine
Nicotinoyl dipeptide-22~0.1–0.35%
Formula
Irritation risk
Low
More about Nicotinoyl dipeptide-22
Paeonia suffruticosa root extract~0.05–0.2%
Irritant · high
Irritation risk
High
Works for
Anti-oxidation
More about Paeonia suffruticosa root extract
Scutellaria baicalensis root extract~0.05–0.15%
Irritant · high
Irritation risk
High
Works for
AntibacterialAnti-oxidationMoisturizingReduces irritationAnti-inflammatory

A plant extract that might contain a compound baicalin that could be helpful in neutralizing free radicals and reducing inflammation in skin. The baicalin concentration in skincare products is often too low for an effective action. Can be used for its fragrant properties

More about Scutellaria baicalensis root extract
Caprylyl glycol~0.1–0.3%
Irritant · medium
Irritation risk
Medium
Works for
Moisturizing

Helps preserve products and creates a nice product texture

More about Caprylyl glycol
Ingredient list view

Saccharomyces ferment, Galactomyces ferment filtrate, Lactobacillus ferment, Water, Camellia sinensis leaf water, Butylene glycol, Glycerin, 1,2-hexanediol, Niacinamide, Levan, Bacillus ferment, Camellia sinensis catechins, Panthenol, Glutathione, Pullulan, Adenosine, Dipotassium glycyrrhizate, Eucalyptus globulus leaf oil, Arginine, Nicotinoyl dipeptide-22, Paeonia suffruticosa root extract, Scutellaria baicalensis root extract, Caprylyl glycol

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
VENN SkincareSynbiotic Defense MistYOUR PRODUCTManyoGalac Niacin 3.0 EssenceSCINICFirst Treatment MistSupereggPURE TRANSPARENCY TREATMENT ESSENCE
Match—85%85%81%
Price$90.00$23.77−$66.23$18.20−$71.80$74.00−$16.00
Shared key ingredients—6 of 136 of 136 of 13
Key difference—Acetyl GlucosamineRetinyl PalmitateAcetyl Glucosamine
Irritancy Medium Low Medium Medium
Drying alcohol————
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Product summary

"Venn - Synbiotic Defense Mist" is effective for: Anti-aging, Evens skin tone and Moisturizing

Ingredient callouts

  • Adenosine 0.15% - 0.60%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
  • Humectants (lactobacillus ferment 4.10% - 6.10%, glycerin 1.30% - 1.90%, pitera 5.20% - 7.80% and panthenol 0.30% - 0.75%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails from 33.00£ up to 580.00£ in the United Kingdom and from 44.00$ up to 85.00$ in the United States.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 26 studies and safety reviews.

  1. 1
    Effects of galactomyces ferment filtrate on epidermal barrier marker caspase-14 in human skin cells.doi.org
  2. 2
    Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manneronlinelibrary.wiley.com
  3. 3
    The Effects of Essence-Formed Cosmetic Ingredients Containing the Galactomyces Ferment Filtrate on Skin Improvements in Keratinization, Pores, Sebum Excretion, Brightness and Acnee-ajbc.org
  4. 4
    Antioxidants cinnamaldehyde and Galactomyces fermentation filtrate downregulate senescence marker CDKN2A/p16INK4A via NRF2 activation in keratinocytesjdsjournal.com
  5. 5
    Galactomyces Ferment Filtrate Suppresses Reactive Oxygen Species Generation and Promotes Cellular Redox Balance in Human Melanocytes via Nrf2-ARE Pathwaypdfs.semanticscholar.org
  6. 6
    Galactomyces Ferment Filtrate Suppresses Melanization and Oxidative Stress in Epidermal Melanocytesetd.ohiolink.edu
VENN Skincare Synbiotic Defense Mist
VENN SkincareSynbiotic Defense Mist
Buy at Venn$90.00Amazon

Affiliate links · As an Amazon Associate, WIMJ earns from qualifying purchases.

Buy at Venn$90.00Amazon

As an Amazon Associate, WIMJ earns from qualifying purchases.