TONYMOLY

TONYMOLY Vital Vita 12 Synergy Ampoule

Name: TONYMOLY - Vital Vita 12 Synergy Ampoule
Brand: TONYMOLY

Efficacy100/100IrritancyHigh

See all ingredients

Works for

Anti-aging

Niacinamide, Centella asiatica extract + 10 more

Works well

What the product description says

“Containing Vitamin C and Squalene, to reveal a more radiant and youthful complexion.”

Source: Skinstore

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: centella asiatica extract, folic acid, lysine, oligopeptide-1.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3–3.7%

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.4–0.6%

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

LysineKey activeEffect: MediumAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

Oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

Folic acidKey activeEffect: MediumCan help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin~0.15–0.25%

TocopherolEffect: Low, below effective dosePure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

Camellia sinensis leaf extractEffect: Low, below effective doseCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.2–0.4%

Sodium ascorbyl phosphateEffect: Low, below effective doseA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.2–0.35%

3-o-ethyl ascorbic acidEffect: Low, below effective doseA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.25%

Aloe barbadensis leaf juiceEffect: Low, below effective doseTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin~0.15–0.25%

Retinyl palmitateUnder-dosedThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect~0.2–0.35%

Evens skin tone

Niacinamide, Glycyrrhiza glabra root extract + 3 more

Works well

What the product description says

“Containing Vitamin C and Squalene, to reveal a more radiant and youthful complexion.”

Source: Skinstore

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: glycyrrhiza glabra root extract.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.2%

3-o-ethyl ascorbic acidUnder-dosedA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products~0.15–0.25%

Moisturizing

Side benefit · Niacinamide, Panthenol + 32 more

Works well

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, inositol.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: squalane, carthamus tinctorius seed oil.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: ceramide np, linoleic acid, niacinamide, oligopeptide-1, panthenol

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~3–3.7%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.65–1%

Linoleic acidHero· EmollientEffect: HighAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.3–0.6%

Ceramide npHero· EmollientEffect: HighA type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin~0.25–0.45%

Oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.35%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4–4.9%

Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.4–0.6%

Oenothera biennis oilKey active· EmollientEffect: HighHelps soften the upper layer of the skin and can support skin barrier function~0.25–0.45%

Carthamus tinctorius seed oilKey active· EmollientEffect: HighAn emollient that helps soften the skin and might help calm down inflammation~0.25–0.45%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

InositolKey active· HumectantEffect: High~0.2–0.4%

LysineKey activeEffect: HighAn amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles~0.2–0.35%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~0.2–0.35%

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.2–0.4%

Calcium pantothenateKey activeEffect: HighHelps support skin barrier function improving skin hydration and reducing sensitivity~0.15–0.3%

Soluble collagenKey active· HumectantEffect: HighA typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin~0.15–0.3%

Corallina officinalis extractKey activeEffect: HighRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.15–0.25%

Crithmum maritimum callus culture filtrateKey activeEffect: HighA plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties~0.15–0.3%

Olea europaea fruit oilKey active· EmollientEffect: MediumAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation~0.15–0.25%

Glyceryl linolenateKey active· EmollientEffect: MediumHelps soften the upper layer of the skin~0.15–0.3%

CyanocobalaminKey activeEffect: HighCan support skin barrier function and reduce inflammation in skin~0.05–0.1%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~5.9–7.2%

Portulaca oleracea extract· HumectantEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.25–0.5%

Polyquaternium-51Effect: LowAn emollient that helps create a nice silky finish on the skin~0.2–0.4%

Octyldodecanol· EmollientEffect: LowAn emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation~0.2–0.4%

BiotinEffect: LowMight have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect~0.15–0.3%

Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~0.15–0.3%

Neopentyl glycol diheptanoate· EmollientEffect: LowHelps soften the upper layer of the skin and create a nice product consistency~0.15–0.3%

Stearic acidEffect: Low, below effective doseHelps oil and water mix together and works as an emollient~0.3–0.5%

LecithinEffect: Low, below effective doseUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~0.25–0.45%

Anti-blemish

Side benefit · Niacinamide, Linoleic acid + 7 more

Works well

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: linoleic acid

Linoleic acidKey activeEffect: MediumAn excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores~0.3–0.6%

Centella asiatica extractEffect: LowA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.4–0.6%

Melia azadirachta leaf extractEffect: LowA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating~0.25–0.45%

Oenothera biennis oilEffect: LowHelps soften the upper layer of the skin and can support skin barrier function~0.25–0.45%

Sodium ascorbyl phosphateUnder-dosedA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C~0.2–0.35%

Anti-oxidation

Side benefit · Centella asiatica extract, Pyridoxine + 19 more

May help

This product contains antioxidants (centella asiatica extract, pyridoxine) that can help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is some human evidence for this effect in skin, though it is smaller or less consistent than the evidence for the best antioxidants.

PyridoxineKey activeEffect: MediumMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating~0.1–0.25%

Carthamus tinctorius seed oilEffect: LowAn emollient that helps soften the skin and might help calm down inflammation~0.25–0.45%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Oenothera biennis oilEffect: LowHelps soften the upper layer of the skin and can support skin barrier function~0.25–0.45%

Portulaca oleracea extractEffect: LowA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin~0.25–0.5%

Pyridoxine hclEffect: LowMight help neutralize free radicals in skin~0.2–0.35%

Aesculus hippocastanum seed extractEffect: LowPlant extract. Might have some anti-oxidant properties. Can be irritating~0.15–0.25%

Arctium lappa root extractEffect: LowPlant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating~0.15–0.25%

Corallina officinalis extractEffect: LowRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants~0.15–0.25%

Melia azadirachta flower extractEffect: LowA plant extract that might be helpful to neutralize free radicals in skin~0.15–0.3%

Ocimum sanctum leaf extractEffect: LowA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals~0.15–0.25%

Vitex agnus-castus extractEffect: LowA plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missing~0.15–0.25%

Pelargonium graveolens flower oilEffect: LowAn essential oil. Can be irritating. Can become an allergen with oxidation~0.15–0.3%

Crithmum maritimum callus culture filtrateEffect: LowA plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties~0.15–0.3%

Glycyrrhiza glabra root extractEffect: LowA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals~0.1–0.2%

Tocopheryl acetateEffect: Low, below effective doseA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.2–0.4%

TocopherolUnder-dosedPure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself~0.2–0.4%

Camellia sinensis leaf extractUnder-dosedCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~0.2–0.4%

Can it cause trouble?

Irritancy

11 strong irritants: Citrus limon peel oil, Citrus aurantium bergamia fruit oil + 9 more — patch-test recommended

High risk

We flagged 40 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Citrus limon peel oilA highly irritating fragranceHigh~0.3–0.5%est.

Melia azadirachta leaf extractA plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritatingHigh~0.25–0.45%est.

Curcuma longa root extractA plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritantHigh~0.15–0.25%est.

Chamomilla recutita flower extractPlant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritatingHigh~0.15–0.25%est.

3-o-ethyl ascorbic acidA vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in productsHigh~0.15–0.25%est.

Citrus aurantium bergamia fruit oilA plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivityHigh~0.1–0.2%est.

Arctium lappa root extractPlant extract. Has some anti-microbial and anti-oxidant properties. Can be irritatingHigh~0.15–0.25%est.

Ocimum sanctum leaf extractA plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicalsHigh~0.15–0.25%est.

Citrus aurantium dulcis oilUsed as a fragrance. It can be irritating and cause photosensitivityHigh~0.15–0.25%est.

Copaifera officinalis resinUsed as a fragranceHigh~0.2–0.35%est.

Cymbopogon martini oilAromatic plant oil used in cosmetics as a fragrance. A likely irritantHigh~0.15–0.25%est.

Pelargonium graveolens flower oilAn essential oil. Can be irritating. Can become an allergen with oxidationHigh~0.15–0.3%est.

Aesculus hippocastanum seed extractPlant extract. Might have some anti-oxidant properties. Can be irritatingHigh~0.15–0.25%est.

AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.2–0.35%est.

Salvia sclarea oil—High~0.2–0.35%est.

Citrus nobilis peel oilA plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skinHigh~0.2–0.35%est.

Retinyl palmitateThree steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effectHigh~0.2–0.35%est.

PyridoxineMight help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritatingHigh~0.1–0.25%est.

Peg-60 hydrogenated castor oilHelps oil and water mix togetherMedium~1.5–1.8%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~1.2–1.5%est.

1,2-hexanediolA preservativeMedium~0.5–0.8%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.4–0.6%est.

EthylhexylglycerinA preservativeMedium~0.45–0.65%est.

Portulaca oleracea extractA plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skinMedium~0.25–0.5%est.

Disodium edtaStabilizes the product formulationMedium~0.2–0.35%est.

Melia azadirachta flower extractA plant extract that might be helpful to neutralize free radicals in skinMedium~0.15–0.3%est.

Vitex agnus-castus extractA plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missingMedium~0.15–0.25%est.

Olea europaea fruit oilAn emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammationMedium~0.15–0.25%est.

Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~0.15–0.3%est.

Glycyrrhiza glabra root extractA plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicalsMedium~0.1–0.2%est.

Aloe barbadensis leaf juiceTraditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skinMedium~0.15–0.25%est.

Hydrogenated phosphatidylcholineHelps oil and water mix togetherMedium~0.15–0.3%est.

Polyglyceryl-2 stearateHelps water and oil mix togetherMedium~0.2–0.35%est.

Sodium ascorbyl phosphateA stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin CMedium~0.2–0.35%est.

Oenothera biennis oilHelps soften the upper layer of the skin and can support skin barrier functionMedium~0.25–0.45%est.

Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.2–0.4%est.

Pyridoxine hclMight help neutralize free radicals in skinMedium~0.2–0.35%est.

PvpHelps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skinMedium~0.2–0.4%est.

Glyceryl arachidonateHelps water and oil mix togetherMedium~0.2–0.35%est.

Thiamine hclCan help attract water to the upper layer of the skin. Is studied as a mosquito repellentMedium~0.05–0.15%est.

Comedogenic

2 ingredients rated 2 or more on the 0–5 pore-clogging scale

2 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Corallina officinalis extractRed algae extract that helps attract water to the upper layer of the skin and might contain antioxidants3/5~0.15–0.25%est.

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.2–0.4%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Butylene glycol~5.9–7.2%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Glycerin~4–4.9%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Niacinamide~3–3.7%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

MoisturizingAnti-blemishEvens skin toneAnti-agingReduces irritationAnti-inflammatoryAntibacterialReduces redness

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Peg/ppg-17/6 copolymer~2.2–2.7%

Formula

Irritation risk: Low

More about Peg/ppg-17/6 copolymer

Bis-peg-15 methyl ether dimethicone~1.8–2.2%

Formula

Irritation risk: Low

Works for

Cleansing

More about Bis-peg-15 methyl ether dimethicone

Peg-60 hydrogenated castor oil~1.5–1.8%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Peg-60 hydrogenated castor oil

Hydroxyacetophenone~1.2–1.5%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

1,2-hexanediol~0.5–0.8%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Panthenol~0.65–1%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Centella asiatica extract~0.4–0.6%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationMoisturizingAnti-inflammatoryReduces rednessAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Ethylhexylglycerin~0.45–0.65%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Xanthan gum~0.35–0.6%

Formula

Irritation risk: Low

Works for

Cleansing

Used to create a thicker product consistency

More about Xanthan gum

Citrus limon peel oil~0.3–0.5%

Irritant · high

Irritation risk: High

A highly irritating fragrance

More about Citrus limon peel oil

Portulaca oleracea extract~0.25–0.5%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidation

A plant extract that has some anti-oxidant activity, but solid research is lacking. Can help attract water to the upper layer of the skin

More about Portulaca oleracea extract

Melia azadirachta leaf extract~0.25–0.45%

Irritant · high

Irritation risk: High

Works for

AntibacterialAnti-blemish

A plant extract that has anti-bacterial properties. Can be used to preserve the product. Can be irritating

More about Melia azadirachta leaf extract

Adenosine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Sodium hyaluronate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Camellia sinensis leaf extract~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract

Disodium edta~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Melia azadirachta flower extract~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might be helpful to neutralize free radicals in skin

More about Melia azadirachta flower extract

Curcuma longa root extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

A plant extract that can contain an active compound curcumin, that may have some anti-inflammatory properties when applied to the skin, but solid research is lacking and the typical concentration used in skincare products is too low. Can be an irritant

More about Curcuma longa root extract

Chamomilla recutita flower extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-inflammatory

Plant extract that can have healing and anti-inflammatory properties. It is a potential allergen and can be irritating

More about Chamomilla recutita flower extract

Vitex agnus-castus extract~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A plant extract that might have some antioxidant properties but evidence of effectiveness in skin is missing

More about Vitex agnus-castus extract

3-o-ethyl ascorbic acid~0.15–0.25%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-oxidationAnti-aging

A vitamin C derivative that is more stable but less potent than pure form of vitamin C. Can help neutralize free radicals and help reduce hyperpigmentation, but the required concentration is likely to be much higher than for the pure form of vitamin C, limiting the ingredient's effectiveness in products

More about 3-o-ethyl ascorbic acid

Citrus aurantium bergamia fruit oil~0.1–0.2%

Irritant · high

Irritation risk: High

A plant oil with a high content of volatile compounds that can irritate the skin and lead to allergic reactions. Can lead to photosensitivity

More about Citrus aurantium bergamia fruit oil

Arctium lappa root extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Plant extract. Has some anti-microbial and anti-oxidant properties. Can be irritating

More about Arctium lappa root extract

Phellinus linteus extract~0.15–0.25%

Formula

Irritation risk: Low

More about Phellinus linteus extract

Ocimum sanctum leaf extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

A plant extract that is rich in a fragrance compound eugenol that is a frequent allergen and can be irritating. It might also contain anti-oxidants to help neutralize free radicals

More about Ocimum sanctum leaf extract

Olea europaea fruit oil~0.15–0.25%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin but is not effective for restoring its barrier function. Might be helpful to calm down inflammation

More about Olea europaea fruit oil

Citrus aurantium dulcis oil~0.15–0.25%

Irritant · high

Irritation risk: High

Used as a fragrance. It can be irritating and cause photosensitivity

More about Citrus aurantium dulcis oil

Squalane~0.2–0.35%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Corallina officinalis extract~0.15–0.25%

Key activeComedogenic 3/5

Irritation risk: Low
Comedogenicity: 3/5

Works for

MoisturizingAnti-oxidation

Red algae extract that helps attract water to the upper layer of the skin and might contain antioxidants

More about Corallina officinalis extract

Cetyl ethylhexanoate~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate

Neopentyl glycol diheptanoate~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin and create a nice product consistency

More about Neopentyl glycol diheptanoate

Soluble collagen~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

A typically plant-derived compound that is supposed mimic human collagen. Cannot penetrate the skin barrier so is not particularly useful in skincare products beyond attracting water to the upper layer of the skin

More about Soluble collagen

Glycyrrhiza glabra root extract~0.1–0.2%

Irritant · medium

Irritation risk: Medium

Works for

Anti-inflammatoryReduces rednessEvens skin toneAnti-oxidationAntibacterial

A plant extract that can help lighten the skin and calm down inflammation. Might be helpful in neutralizing free radicals

More about Glycyrrhiza glabra root extract

Paeonia albiflora root extract~0.15–0.25%

Formula

Irritation risk: Low

More about Paeonia albiflora root extract

Pueraria thunbergiana root extract~0.1–0.25%

Formula

Irritation risk: Low

More about Pueraria thunbergiana root extract

Aloe barbadensis leaf juice~0.15–0.25%

Irritant · medium

Irritation risk: Medium

Works for

MoisturizingAntibacterialReduces rednessAnti-inflammatoryReduces irritationAnti-agingAnti-blemish

Traditionally used to treat sunburns, dermatitis and inflammation, but evidence for its effectiveness is lacking. The extract can contain humectants that help attract water into the skin

More about Aloe barbadensis leaf juice

Cnidium officinale root extract~0.15–0.25%

Formula

Irritation risk: Low

More about Cnidium officinale root extract

Hydrogenated phosphatidylcholine~0.15–0.3%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together

More about Hydrogenated phosphatidylcholine

Peg-35 castor oil~0.15–0.3%

Formula

Irritation risk: Low

Works for

Cleansing

More about Peg-35 castor oil

Copaifera officinalis resin~0.2–0.35%

Irritant · high

Irritation risk: High

Used as a fragrance

More about Copaifera officinalis resin

Polyglyceryl-10 myristate~0.15–0.3%

Formula

Irritation risk: Low

More about Polyglyceryl-10 myristate

Cymbopogon martini oil~0.15–0.25%

Irritant · high

Irritation risk: High

Aromatic plant oil used in cosmetics as a fragrance. A likely irritant

More about Cymbopogon martini oil

Calcium pantothenate~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingReduces irritation

Helps support skin barrier function improving skin hydration and reducing sensitivity

More about Calcium pantothenate

Maltodextrin~0.2–0.35%

Formula

Irritation risk: Low

Works for

Mattifying

Used to stabilize the product formulation and can help absorb oil

More about Maltodextrin

Sodium starch octenylsuccinate~0.15–0.3%

Formula

Irritation risk: Low

More about Sodium starch octenylsuccinate

Pelargonium graveolens flower oil~0.15–0.3%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

An essential oil. Can be irritating. Can become an allergen with oxidation

More about Pelargonium graveolens flower oil

Aesculus hippocastanum seed extract~0.15–0.25%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Plant extract. Might have some anti-oxidant properties. Can be irritating

More about Aesculus hippocastanum seed extract

Cetearyl alcohol~0.2–0.4%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Crithmum maritimum callus culture filtrate~0.15–0.3%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

A plant cell extract that helps attract water to the upper layer of the skin and might have some anti-oxidant properties

More about Crithmum maritimum callus culture filtrate

Polyglyceryl-2 stearate~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-2 stearate

Stearic acid~0.3–0.5%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Helps oil and water mix together and works as an emollient

More about Stearic acid

Alcohol~0.2–0.35%

Irritant · high

Irritation risk: High

Works for

Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol

Sodium ascorbyl phosphate~0.2–0.35%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Anti-blemishAnti-oxidationAnti-aging

A stable derivative of vitamin C. It is oil-soluble which means it is more likely to penetrate the skin compared to the pure form of vitamin C (which is water-soluble), but it is less bio-available and is way less effective in stimulating collagen and reducing wrinkles compared to the pure form of vitamin C (L-ascorbic acid) and its other derivatives (for example, magnesium ascorbyl phosphate). At the same time, this vitamin C derivative has been shown in studies to be effective in reducing acne, blemishes and clogged pores. It is less irritating then the pure form of vitamin C

More about Sodium ascorbyl phosphate

Salvia sclarea oil~0.2–0.35%

Irritant · high

Irritation risk: High

More about Salvia sclarea oil

Citrus nobilis peel oil~0.2–0.35%

Irritant · high

Irritation risk: High

A plant oil with high content of volatile compounds that, especially when exposed to air, can cause allergic reactions and irritate the skin

More about Citrus nobilis peel oil

Carthamus tinctorius seed oil~0.25–0.45%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

An emollient that helps soften the skin and might help calm down inflammation

More about Carthamus tinctorius seed oil

Oenothera biennis oil~0.25–0.45%

Key activeIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-blemishAnti-oxidationAnti-inflammatory

Helps soften the upper layer of the skin and can support skin barrier function

More about Oenothera biennis oil

Octyldodecanol~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps to soften the skin and create a pleasant product texture and stabilize the formulation

More about Octyldodecanol

Tocopheryl acetate~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate

Pyridoxine hcl~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Anti-oxidation

Might help neutralize free radicals in skin

More about Pyridoxine hcl

Polysorbate 20~0.25–0.4%

Formula

Irritation risk: Low

Works for

Cleansing

Helps oil and water mix together

More about Polysorbate 20

Tocopherol~0.2–0.4%

Under-dosed

Irritation risk: Low

Works for

Anti-oxidationMoisturizingAnti-inflammatoryAnti-aging

Pure form of vitamin E. Can help moisturise and protect the skin from free radicals. Often used to help stabilise other ingredients or the formula itself

More about Tocopherol

Polyquaternium-51~0.2–0.4%

Formula

Irritation risk: Low

Works for

Moisturizing

An emollient that helps create a nice silky finish on the skin

More about Polyquaternium-51

Pvp~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Helps evenly disperse other ingredients in a formulation and create an even layer on the surface of the skin

More about Pvp

Ceramide np~0.25–0.45%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingReduces irritationAnti-inflammatory

A type of lipid similar to ceramides naturally present in skin. Helps to soften the upper layer of the skin and supports the skin barrier function to keep it hydrated. Can help to prevent inflammation in skin

More about Ceramide np

Sodium acetate~0.2–0.35%

Formula

Irritation risk: Low

More about Sodium acetate

Lecithin~0.25–0.45%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin

Inositol~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

More about Inositol

Lysine~0.2–0.35%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-aging

An amino-acid that helps to attract water to the upper layer of the skin. In combination with other amino-acids, might help to reduce fine lines and wrinkles

More about Lysine

Retinyl palmitate~0.2–0.35%

Under-dosedIrritant · high

Irritation risk: High

Works for

Evens skin toneAnti-blemishAnti-agingExfoliation

Three steps removed from the active form of vitamin A - retinoic acid. To have an effect in the skin, it first needs to be converted twice to become the retinoic acid. This means it is less potent than retinol, but could also be less irritating. Once converted to the retinoic acid in the skin, it helps against all signs of aging, improves skin cell turnover and helps fight blemishes and clogged pores. However, in many cosmetic formulations, it is used in a concentration that is too low to have the full effect

More about Retinyl palmitate

Linoleic acid~0.3–0.6%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingCleansingAnti-blemish

An excellent emollient. Helps soften the skin, restore its barrier function, and can help to calm down inflammation. It can be helpful to prevent blemishes and clogged pores

More about Linoleic acid

Silica~0.3–0.6%

Formula

Irritation risk: Low

Used to absorb oil and can temporarily mattify skin

More about Silica

Oligopeptide-1~0.2–0.35%

Hero · Moisturizing

Irritation risk: Low

Works for

MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Oligopeptide-1

Fullerenes~0.2–0.35%

Formula

Irritation risk: Low

More about Fullerenes

Biotin~0.15–0.3%

Formula

Irritation risk: Low

Works for

Moisturizing

Might have some moisturising properties. Is not effective when applied topically beyond some moisturizing effect

More about Biotin

Glyceryl arachidonate~0.2–0.35%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Glyceryl arachidonate

Glyceryl linolenate~0.15–0.3%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Glyceryl linolenate

Folic acid~0.15–0.25%

Key active

Irritation risk: Low

Works for

Anti-aging

Can help stimulate collagen production in skin. While available studies are promising, more research is needed to confirm the efficacy in skin

More about Folic acid

Pyridoxine~0.1–0.25%

Key activeIrritant · high

Irritation risk: High

Works for

Anti-oxidation

Might help neutralize free radicals in skin, but evidence of effectiveness in skin is lacking. It might be irritating

More about Pyridoxine

Thiamine hcl~0.05–0.15%

Irritant · medium

Irritation risk: Medium

Can help attract water to the upper layer of the skin. Is studied as a mosquito repellent

More about Thiamine hcl

Cyanocobalamin~0.05–0.1%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-inflammatory

Can support skin barrier function and reduce inflammation in skin

More about Cyanocobalamin

Ingredient list view

Water, Butylene glycol, Glycerin, Niacinamide, Peg/ppg-17/6 copolymer, Bis-peg-15 methyl ether dimethicone, Peg-60 hydrogenated castor oil, Hydroxyacetophenone, 1,2-hexanediol, Panthenol, Centella asiatica extract, Ethylhexylglycerin, Xanthan gum, Citrus limon peel oil, Portulaca oleracea extract, Melia azadirachta leaf extract, Adenosine, Sodium hyaluronate, Camellia sinensis leaf extract, Disodium edta, Melia azadirachta flower extract, Curcuma longa root extract, Chamomilla recutita flower extract, Vitex agnus-castus extract, 3-o-ethyl ascorbic acid, Citrus aurantium bergamia fruit oil, Arctium lappa root extract, Phellinus linteus extract, Ocimum sanctum leaf extract, Olea europaea fruit oil, Citrus aurantium dulcis oil, Squalane, Corallina officinalis extract, Cetyl ethylhexanoate, Neopentyl glycol diheptanoate, Soluble collagen, Glycyrrhiza glabra root extract, Paeonia albiflora root extract, Pueraria thunbergiana root extract, Aloe barbadensis leaf juice, Cnidium officinale root extract, Hydrogenated phosphatidylcholine, Peg-35 castor oil, Copaifera officinalis resin, Polyglyceryl-10 myristate, Cymbopogon martini oil, Calcium pantothenate, Maltodextrin, Sodium starch octenylsuccinate, Pelargonium graveolens flower oil, Aesculus hippocastanum seed extract, Cetearyl alcohol, Crithmum maritimum callus culture filtrate, Polyglyceryl-2 stearate, Stearic acid, Alcohol, Sodium ascorbyl phosphate, Salvia sclarea oil, Citrus nobilis peel oil, Carthamus tinctorius seed oil, Oenothera biennis oil, Octyldodecanol, Tocopheryl acetate, Pyridoxine hcl, Polysorbate 20, Tocopherol, Polyquaternium-51, Pvp, Ceramide np, Sodium acetate, Lecithin, Inositol, Lysine, Retinyl palmitate, Linoleic acid, Silica, Oligopeptide-1, Fullerenes, Biotin, Glyceryl arachidonate, Glyceryl linolenate, Folic acid, Pyridoxine, Thiamine hcl, Cyanocobalamin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	TONYMOLYVital Vita 12 Synergy AmpouleYOUR PRODUCT	SKIN&LABVitamin C Brightening Serum	ArenciaDeep Water Surge Serum 30	MedicubeGlutathione Glow Serum
Match	—	83%	82%	82%
Price	—	$12.69	$15.57	$15.61
Shared key ingredients	—	12 of 26	10 of 26	9 of 26
Key difference	—	Retinol	Copper Tripeptide-1	Caprylic/Capric Triglyceride
Irritancy	High	Medium	Medium	Medium
Drying alcohol	Contains drying alcohol	—	—	—
	View product	Shop	Shop	Shop

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Product summary

"TONYMOLY - Vital Vita 12 Synergy Ampoule" is effective for: Anti-inflammatory, Anti-blemish, Moisturizing, Evens skin tone and Anti-aging

Ingredient callouts

A good concentration of Niacinamide (3.00% - 3.70%). Niacinamide is a well-studied multi-tasking active. It is stable, and can work well in almost any hydrating formulation. There is solid evidence that Niacinamide can help support skin barrier, regulate oil production and reduce acne and clogged pores. It also helps to fight photodamage and improve the skin tone, reducing pigmentation marks.
This product includes a form of Retinoids (vitamin A) - retinyl palmitate 0.20% - 0.35%, but this type of vitamin A is not very effective. It could in theory help with fine lines and wrinkles, but the effect is most likely minimal.
Ceramides (ceramide np 0.25% - 0.45%). Ceramides are an important part of our natural skin barrier. The Ceramides used in skincare are synthetic or come from plants. They help soften the skin and can help "fill the gaps" in the skin barrier, keeping the skin hydrated and resilient for longer.
Peptides (oligopeptide-1 0.20% - 0.35%). There are many different kind of Peptides and they are naturally present in our skin. They all are a combination of aminoacids. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The science is still not settled on how effective Peptides are in skincare, but it is very likely that they have a benefit. They might help restore the skin barrier and fight the signs of aging. At the very least, Peptides work as humectants: they attract water to the upper layer of the skin and improve its hydration.
Adenosine 0.25% - 0.45%. It is a chemical present inside our skin cells. A clinical trial confirmed that topical application of Adenosine in a low concentration can reduce dynamic wrinkles (these are the wrinkles that appear with age in a places where our mimic is the most active, for example, in the corners of the eyes or on the forehead).
Panthenol (pro-vitamin B5) at about 0.65% - 1.00% concentration. In this concentration, Panthenol works effectively to improve the skin barrier and reduce inflammation.
Humectants (soluble collagen 0.15% - 0.30%, sodium hyaluronate 0.20% - 0.40%, panthenol 0.65% - 1.00%, inositol 0.20% - 0.40% and glycerin 4.00% - 4.90%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

About the brand

According to Cruelty-Free Kitty "TONYMOLY" is cruelty free and so is its parent company.

Price

The product retails for 20.00$ in the United States and for 28.00CA$ in Canada.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 50 studies and safety reviews.

1
Glycerol and the skin: holistic approach to its origin and functionsncbi.nlm.nih.gov
2
Niacinamide - mechanisms of action and its topical use in dermatologyncbi.nlm.nih.gov
3
Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x ncbi.nlm.nih.gov
4
The influence of alkane chain length on the skin irritation potential of 1,2-alkanediolsncbi.nlm.nih.gov
5
Skin moisturizing effects of panthenol-based formulationspdfs.semanticscholar.org
6
Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmeticscir-safety.org
7
Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Modelmdpi.com
8
Centella asiatica in cosmetologyncbi.nlm.nih.gov
9
Triterpene Composition and Bioactivities of Centella asiatica mdpi.com
10
Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblastsonlinelibrary.wiley.com
11
Assessment report on Centella asiatica (L.) Urban, herbaema.europa.eu
12
Contact dermatitis due to Madecassolonlinelibrary.wiley.com
13
The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trialliebertpub.com
14
Portulaca oleracea (purslane)mdedge.com
15
Melia azedarachmdedge.com
16
Preliminary and Pharmacological Profile of Melia azedarach L.: An Overviewjapsonline.com
17
Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS techniquencbi.nlm.nih.gov
18
Hyaluronic acid: A key molecule in skin agingncbi.nlm.nih.gov
19
Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin careresearchgate.net
20
Vaughn, A. R., Branum, A., & Sivamani, R. K. (2016). Effects of Turmeric (Curcuma longa) on Skin Health: A Systematic Review of the Clinical Evidence. Phytotherapy Research, 30(8), 1243–1264. doi:10.1002/ptr.5640ncbi.nlm.nih.gov
21
Antioxidant Ability and Stability Studies of 3-O-Ethyl Ascorbic Acid, a Cosmetic Tyrosinase Inhibitorncbi.nlm.nih.gov
22
Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmeticscir-safety.org
23
Oxidized citrus oil (R-limonene): A frequent skin sensitizer in Europesciencedirect.com
24
Air oxidation increases skin irritation from fragrance terpenesonlinelibrary.wiley.com
25
Contact dermatitis as an adverse reaction to some topically used European herbal medicinal products – part 1: Achillea millefolium–Curcuma longaonlinelibrary.wiley.com
26
Use of “natural” oils for moisturization: Review of olive, coconut, and sunflower seed oilonlinelibrary.wiley.com
27
Oxidized citrus oil (R-limonene): A frequent skin sensitizer in Europesciencedirect.com
28
Calcium pantothenate modulates gene expression in proliferating human dermal fibroblastsonlinelibrary.wiley.com
29
Dexpanthenol Modulates Gene Expression in Skin Wound Healing in vivokarger.com
30
Dexapanthenol enhances skin barrier repair and reduces inflammation after sodium lauryl sulphate-induced irritationtandfonline.com
31
Fragrance Compound Geraniol Forms Contact Allergens on Air Exposure. Identification and Quantification of Oxidation Products and Effect on Skin Sensitization
32
Safety Assessment of Polyglyceryl Fatty Acid Esters as Used in Cosmeticscir-safety.org
33
Sodium ascorbyl phosphate shows in vitro and in vivo efficacy in the prevention and treatment of acne vulgarisncbi.nlm.nih.gov
34
Sodium ascorbyl phosphate in topical microemulsionssciencedirect.com
35
Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmeticseuropepmc.org
36
Regulation of collagen synthesis in human dermal fibroblasts by the sodium and magnesium salts of ascorbyl-2-phosphatekarger.com
37
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TONYMOLYVital Vita 12 Synergy Ampoule

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