Theralogic

Theralogic Madecell Derma Repair B5 Cream

Name: Theralogic - Madecell Derma Repair B5 Cream
Brand: Theralogic

Efficacy100/100IrritancyHigh

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Works for

3 of 3 advertised claims delivered

Moisturizing

Madecassoside, Niacinamide + 16 more

Strong evidence

What the product description says

“Each ingredient mixed in madecell solution provides synergy for moisturizing, hydration, and soothing.”

Source: N/A

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: glycerin, sodium hyaluronate.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide, panthenol

Sodium hyaluronateKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Attracts water into the upper layer of the skin~0.2–0.4%

SqualaneKey active· Emollient, OcclusiveEffect: HighAn oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.~1.5–1.9%

Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~2.4–2.9%

GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~4.9–6%

Vinyl dimethiconeKey active· EmollientEffect: HighA type of silicone that helps to create a nice product texture and soften the upper layer of the skin~0.4–0.6%

Synthetic beeswaxKey activeEffect: HighHelps soften the upper layer of the skin~0.4–0.6%

MadecassosideHeroEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.2–0.35%

Mangifera indica seed butterKey activeEffect: HighHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.5–0.75%

NiacinamideHeroEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.5%

PanthenolHero· HumectantEffect: HighHelps attract water to the upper layer of the skin and can help improve skin barrier function~0.55–0.85%

Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~2–2.4%

Diisostearyl malateKey active· EmollientEffect: MediumHelps to soften the upper layer of the skin~0.45–0.7%

AdenosineKey activeEffect: MediumMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~0.5–0.75%

Cetyl ethylhexanoate· EmollientEffect: LowAn emollient that helps soften the skin and creates a thicker product texture~1–1.2%

Butylene glycol· HumectantEffect: LowUsed to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin~0.15–0.25%

Hydrogenated polydecene· EmollientEffect: LowHelps to soften the upper layer of the skin and create a nice product texture~3–3.7%

Centella asiatica extractUnder-dosedEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.3%

Evens skin tone

Niacinamide, Madecassoside

Strong evidence

This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.

Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.

NiacinamideKey activeEffect: HighIs proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production~1.2–1.5%

MadecassosideEffect: LowAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.2–0.35%

Anti-blemish

Niacinamide, Centella asiatica extract

Strong evidence

This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.

Centella asiatica extractEffect: Low, below effective doseA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.3%

Anti-oxidation

Not advertised by the brand · Madecassoside, Adenosine + 4 more

Strong evidence

This product contains antioxidants (madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).

MadecassosideKey activeEffect: HighAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.2–0.35%

AdenosineEffect: LowMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

Centaurea cyanus flower extractEffect: LowA plant extract that might have antibacterial effect and help neutralize free radicals~0.15–0.3%

Mangifera indica seed butterEffect: LowHelps to soften the upper layer of the skin and might have some anti-oxidant effect~0.5–0.75%

Salvia sclarea extractEffect: LowUsed as a fragrance. Can be irritating~0.15–0.3%

Centella asiatica extractUnder-dosedEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.15–0.3%

Anti-aging

Not advertised by the brand · Niacinamide, Adenosine + 2 more

Strong evidence

This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.

These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: madecassoside.

Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.

AdenosineKey activeEffect: HighMight help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)~0.25–0.45%

MadecassosideKey activeEffect: MediumAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations~0.2–0.35%

Can it cause trouble?

Irritancy

3 strong irritants: Salvia sclarea extract, Lavandula angustifolia flower extract + 1 more — patch-test recommended

High risk

We flagged 16 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.

IngredientFunctionIrritationEst. amount

Salvia sclarea extractUsed as a fragrance. Can be irritatingHigh~0.15–0.3%est.

Lavandula angustifolia flower extractEssential oil that can be irritatingHigh~0.25–0.45%est.

Chamomilla recutita flower/leaf extract—High~0.15–0.3%est.

Centaurea cyanus flower extractA plant extract that might have antibacterial effect and help neutralize free radicalsHigh~0.15–0.3%est.

Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~2.4–2.9%est.

Polyglyceryl-3 methylglucose distearateHelps water and oil mix togetherMedium~1.6–2%est.

Cetyl ethylhexanoateAn emollient that helps soften the skin and creates a thicker product textureMedium~1–1.2%est.

1,2-hexanediolA preservativeMedium~0.65–0.95%est.

Diisostearyl malateHelps to soften the upper layer of the skinMedium~0.45–0.7%est.

HydroxyacetophenoneUsed to increase effectiveness of preservativesMedium~0.3–0.55%est.

Sodium polyacryloyldimethyl taurateHelps oil and water mix togetherMedium~0.25–0.45%est.

Disodium edtaStabilizes the product formulationMedium~0.2–0.4%est.

Caprylyl/capryl glucosideHelps oil and water mix together. Can be used as a cleansing agentMedium~0.3–0.5%est.

MadecassosideAn antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulationsMedium~0.2–0.35%est.

Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.15–0.3%est.

EthylhexylglycerinA preservativeMedium~0.05–0.15%est.

Comedogenic

1 ingredient rated 2 or more on the 0–5 pore-clogging scale

1 flagged

These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.

IngredientFunctionRatingEst. amount

Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~2–2.4%est.

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TOSOWOONG Jeju Mayu Cream

Closest match98% match

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Ingredients

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Water~45–55%

Formula

Irritation risk: Low

Plain old water

More about Water

Glycerin~4.9–6%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin

Dipropylene glycol~4–4.9%

Formula

Irritation risk: Low

Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying

More about Dipropylene glycol

Hydrogenated polydecene~3–3.7%

Formula

Irritation risk: Low

Works for

Moisturizing

Helps to soften the upper layer of the skin and create a nice product texture

More about Hydrogenated polydecene

Caprylic/capric triglyceride~2.4–2.9%

Key activeIrritant · medium

Irritation risk: Medium

Works for

Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride

Cetearyl alcohol~2–2.4%

Key activeComedogenic 2/5

Irritation risk: Low
Comedogenicity: 2/5

Works for

CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol

Polyglyceryl-3 methylglucose distearate~1.6–2%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps water and oil mix together

More about Polyglyceryl-3 methylglucose distearate

Squalane~1.5–1.9%

Key active

Irritation risk: Low

Works for

Moisturizing

An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.

More about Squalane

Niacinamide~1.2–1.5%

Hero · Moisturizing, Anti-blemish

Irritation risk: Low

Works for

Anti-agingEvens skin toneMoisturizingAnti-blemishReduces irritationAnti-inflammatoryReduces rednessAntibacterial

Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production

More about Niacinamide

Cetyl ethylhexanoate~1–1.2%

Irritant · medium

Irritation risk: Medium

Works for

Moisturizing

An emollient that helps soften the skin and creates a thicker product texture

More about Cetyl ethylhexanoate

1,2-hexanediol~0.65–0.95%

Irritant · medium

Irritation risk: Medium

A preservative

More about 1,2-hexanediol

Panthenol~0.55–0.85%

Hero · Moisturizing

Irritation risk: Low

Works for

Reduces rednessMoisturizingReduces irritation

Helps attract water to the upper layer of the skin and can help improve skin barrier function

More about Panthenol

Mangifera indica seed butter~0.5–0.75%

Key active

Irritation risk: Low

Works for

MoisturizingAnti-oxidation

Helps to soften the upper layer of the skin and might have some anti-oxidant effect

More about Mangifera indica seed butter

Glyceryl stearate~0.5–0.75%

Formula

Irritation risk: Low

Works for

CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate

Diisostearyl malate~0.45–0.7%

Key activeIrritant · medium

Irritation risk: Medium

Works for

CleansingMoisturizing

Helps to soften the upper layer of the skin

More about Diisostearyl malate

Microcrystalline wax~0.45–0.65%

Formula

Irritation risk: Low

Used to create a thicker product consistency

More about Microcrystalline wax

Synthetic beeswax~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

Helps soften the upper layer of the skin

More about Synthetic beeswax

Vinyl dimethicone~0.4–0.6%

Key active

Irritation risk: Low

Works for

Moisturizing

A type of silicone that helps to create a nice product texture and soften the upper layer of the skin

More about Vinyl dimethicone

Hydroxyacetophenone~0.3–0.55%

Irritant · medium

Irritation risk: Medium

Used to increase effectiveness of preservatives

More about Hydroxyacetophenone

Ammonium acryloyldimethyltaurate/vp copolymer~0.25–0.5%

Formula

Irritation risk: Low

Increases thickness of a product. Texture enhancer for oil-in-water emulsions

More about Ammonium acryloyldimethyltaurate/vp copolymer

Sodium polyacryloyldimethyl taurate~0.25–0.45%

Irritant · medium

Irritation risk: Medium

Helps oil and water mix together

More about Sodium polyacryloyldimethyl taurate

Adenosine~0.25–0.45%

Key active

Irritation risk: Low

Works for

Anti-agingMoisturizingAnti-oxidation

Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)

More about Adenosine

Disodium edta~0.2–0.4%

Irritant · medium

Irritation risk: Medium

Stabilizes the product formulation

More about Disodium edta

Caprylyl/capryl glucoside~0.3–0.5%

Irritant · medium

Irritation risk: Medium

Works for

Cleansing

Helps oil and water mix together. Can be used as a cleansing agent

More about Caprylyl/capryl glucoside

Sodium hyaluronate~0.2–0.4%

Key active

Irritation risk: Low

Works for

Moisturizing

One of the best moisturizing ingredients. Attracts water into the upper layer of the skin

More about Sodium hyaluronate

Salvia sclarea extract~0.15–0.3%

Irritant · high

Irritation risk: High

Works for

Anti-oxidation

Used as a fragrance. Can be irritating

More about Salvia sclarea extract

Madecassoside~0.2–0.35%

Hero · MoisturizingIrritant · medium

Irritation risk: Medium

Works for

MoisturizingAnti-oxidationAnti-agingEvens skin tone

An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations

More about Madecassoside

Lavandula angustifolia flower extract~0.25–0.45%

Irritant · high

Irritation risk: High

Essential oil that can be irritating

More about Lavandula angustifolia flower extract

Hyacinthus orientalis extract~0.15–0.3%

Formula

Irritation risk: Low

More about Hyacinthus orientalis extract

Chamomilla recutita flower/leaf extract~0.15–0.3%

Irritant · high

Irritation risk: High

More about Chamomilla recutita flower/leaf extract

Centaurea cyanus flower extract~0.15–0.3%

Irritant · high

Irritation risk: High

Works for

Anti-oxidationAnti-inflammatory

A plant extract that might have antibacterial effect and help neutralize free radicals

More about Centaurea cyanus flower extract

Butylene glycol~0.15–0.25%

Formula

Irritation risk: Low

Works for

Moisturizing

Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin

More about Butylene glycol

Borago officinalis extract~0.15–0.3%

Formula

Irritation risk: Low

More about Borago officinalis extract

Centella asiatica extract~0.15–0.3%

Under-dosedIrritant · medium

Irritation risk: Medium

Works for

Reduces irritationReduces rednessMoisturizingAnti-inflammatoryAnti-agingAnti-oxidationAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract

Ethylhexylglycerin~0.05–0.15%

Irritant · medium

Irritation risk: Medium

A preservative

More about Ethylhexylglycerin

Ingredient list view

Water, Glycerin, Dipropylene glycol, Hydrogenated polydecene, Caprylic/capric triglyceride, Cetearyl alcohol, Polyglyceryl-3 methylglucose distearate, Squalane, Niacinamide, Cetyl ethylhexanoate, 1,2-hexanediol, Panthenol, Mangifera indica seed butter, Glyceryl stearate, Diisostearyl malate, Microcrystalline wax, Synthetic beeswax, Vinyl dimethicone, Hydroxyacetophenone, Ammonium acryloyldimethyltaurate/vp copolymer, Sodium polyacryloyldimethyl taurate, Adenosine, Disodium edta, Caprylyl/capryl glucoside, Sodium hyaluronate, Salvia sclarea extract, Madecassoside, Lavandula angustifolia flower extract, Hyacinthus orientalis extract, Chamomilla recutita flower/leaf extract, Centaurea cyanus flower extract, Butylene glycol, Borago officinalis extract, Centella asiatica extract, Ethylhexylglycerin

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
	TheralogicMadecell Derma Repair B5 CreamYOUR PRODUCT	TOSOWOONGJeju Mayu Cream	Centellian24Madeca Cream Time Reverse	MEDIHEALMadecassoside Derma Cream Blemish Repair
Match	—	98%	96%	96%
Price	—	—	$13.32	$25.36
Shared key ingredients	—	9 of 12	9 of 12	8 of 12
Key difference	—	Oligopeptide-1	Retinol	Ceramide Np
Irritancy	High	Medium	High	Medium
Drying alcohol	—	—	—	—
	View product	Shop	Shop	Shop

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Product summary

Based on the ingredient list, "Theralogic - Madecell Derma Repair B5 Cream" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol, glycerin, sodium hyaluronate and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Vinyl dimethicone, caprylic/capric triglyceride, squalane, cetearyl alcohol and diisostearyl malate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.

Ingredient callouts

Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.20% - 0.35% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
An effective concentration of Panthenol (pro-vitamin B5) - about 0.55% - 0.85%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.

This product contains ingredients that could be beneficial, but their concentrations are too low in this formulation: centella asiatica extract

Irritation risk

This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here

You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.