Works for:
based on ingredients and %- Moisturizing
- Evens skin tone
- Anti-blemish
- Anti-oxidation
Can it cause trouble?
- Irritation risk: high
- Comedogenic risk ingredients: 1
Key actives
Product Summary
Based on the ingredient list, "Theralogic - Madecell Derma Repair B5 Cream" can work well for skin moisturization. The formulation is based on a combination of good humectants and emollients. Both are needed to increase the skin hydration level. Humectants in this product (panthenol, glycerin, sodium hyaluronate and butylene glycol) help to increase the water content in the upper layer of the skin. (These ingredients do so by "capturing" water molecules from the outside air or from within the deeper layers of the skin). Vinyl dimethicone, caprylic/capric triglyceride, squalane, cetearyl alcohol and diisostearyl malate in this product help decrease the water evoporation from the skin, so that it stays hydrated for longer. These ingredients also soften the skin and take away the feeling of tightness and dryness.
Ingredient callouts
- Adenosine 0.25% - 0.45%. It is a compound that in involved in many biological processes inside the skin cells. According one high-quality clinical trial, topical Adenosine in low concentrations can somewhat help improve "deep wrinkles" - the wrinkles that appear with age in places where our faces are most dynamic (for example, on the forehead or in the corners of the eyes).
- Actives derived from an extract of the Centella Asiatica plant (also known as Gotu Kola) - madecassoside 0.20% - 0.35% The Centella Asiatica Actives, even in low concentration, can help reduce inflammation in skin, strengthen the skin barrier and reduce photodamage. They can also help to decrease scarring.
- An effective concentration of Panthenol (pro-vitamin B5) - about 0.55% - 0.85%. Panthenol helps strengthen the skin barrier, improve hydration and reduce inflammation in skin.
Irritation risk
This formulation includes some common irritants, including ingredients that do not provide a benefit for the skin. We assess the overall irritancy of this moisturizer to be high. For a detailed overview of all potential irritants: click here
You can see the detailed formula review with the breakdown of all actives in the product and the full ingredient list with estimated concentrations in the tables below.
Anti-aging
This product can help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness because it contains adenosine, niacinamide.
These ingredients in the product can also be helpful, even though there is less evidence for their effectiveness: madecassoside.
Keep in mind that it typically takes at least 6 weeks to notice any results because the changes that are needed to improve fine lines and elasticity happen in the deeper layers of the skin. No topical anti-aging product can “erase” wrinkles or fully reverse signs of aging.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Anti-blemish
This product can help reduce breakouts and clogged pores because it contains the following ingredient: niacinamide. This ingredient is used for treating acne and can have a noticeable effect.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Anti-oxidation
This product contains antioxidants (madecassoside) that can help neutralize free radicals in skin. By doing so, they can lessen the damage the skin gets from the UV light (sun).
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
A plant extract that might have antibacterial effect and help neutralize free radicals
Helps to soften the upper layer of the skin and might have some anti-oxidant effect
Used as a fragrance. Can be irritating
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Evens skin tone
This product can help reduce hypepigmentation and even out the skin tone because it contains the following effective ingredients: niacinamide
The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually can help even out the skin tone: madecassoside.
Keep in mind that you would need to apply any topical skincare targetted at hypigmentation consistently for a couple of months to get a result. No topical skincare product can help get rid of hyperpigmentation (including post-acne marks and age spots) instantly.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Moisturizing
What does the product description say?
Each ingredient mixed in madecell solution provides synergy for moisturizing, hydration, and soothing.
Source: N/A
This product can help improve hydration of the skin with the two types of ingredients.
The first type is called “humectants”:
these ingredients help attract water.
When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from
within deeper layers of the skin. The following ingredients in this product do the job:
glycerin, sodium hyaluronate.
This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: caprylic/capric triglyceride, squalane.
The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: madecassoside, niacinamide, panthenol
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A type of silicone that helps to create a nice product texture and soften the upper layer of the skin
Helps soften the upper layer of the skin
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Helps to soften the upper layer of the skin and might have some anti-oxidant effect
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
Helps attract water to the upper layer of the skin and can help improve skin barrier function
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
Helps to soften the upper layer of the skin
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
An emollient that helps soften the skin and creates a thicker product texture
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
Helps to soften the upper layer of the skin and create a nice product texture
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
How honest is this product?
| Promise | Can it deliver? |
|---|---|
| Moisturizing | |
| Evens skin tone | |
| Anti-blemish |
Total Promises Fulfilled score: 100/100.
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Potential irritants
Comedogenic ingredients
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Key Actives
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps to soften the upper layer of the skin and might have some anti-oxidant effect
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Helps soften the upper layer of the skin
A type of silicone that helps to create a nice product texture and soften the upper layer of the skin
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
Potential irritants
Essential oil that can be irritating
A plant extract that might have antibacterial effect and help neutralize free radicals
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
An emollient that helps soften the skin and creates a thicker product texture
Helps oil and water mix together. Can be used as a cleansing agent
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Comedogenic ingredients
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
All ingredients
One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant
Helps to dissolve other ingredients in a formulation. Slows down the rate of product drying
Helps to soften the upper layer of the skin and create a nice product texture
A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin
A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture
An oil naturally present in skin. Works as an emollient to soften the skin and form a protective layer on its surface without a greasy feeling.
Is proven to be effective in reducing blemishes, evening out skin tone and helping to improve lines and wrinkles. It helps the skin to repair sun damage, calm down inflammation and keep maintain good levels of moisture. The concentration of about 2% is effective for supporting the skin barrier and evening out the skin tone. Concentration of 4-6% is better for helping with acne and balancing the sebum production
An emollient that helps soften the skin and creates a thicker product texture
Helps attract water to the upper layer of the skin and can help improve skin barrier function
Helps to soften the upper layer of the skin and might have some anti-oxidant effect
An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together
A type of silicone that helps to create a nice product texture and soften the upper layer of the skin
Increases thickness of a product. Texture enhancer for oil-in-water emulsions
Might help improve cell turnover and reduce inflammation in skin. One study shows that the ingredients might be able to help reduce dynamic wrinkles (for example, in the corners of the eyes or on the forehead)
Helps oil and water mix together. Can be used as a cleansing agent
One of the best moisturizing ingredients. Attracts water into the upper layer of the skin
An antioxidant that is typically derived from plant Centella Asiatica. It can help neutralize free radicals in skin and support skin barrier function. It could, however, itself be irritating. It is often unstable in formulations
Essential oil that can be irritating
A plant extract that might have antibacterial effect and help neutralize free radicals
Used to create a nice product texture and help delivery of other ingredients. Might be somewhat helpful in attracting water to the upper layer of the skin
A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.
Ingredient list view
Water, Glycerin, Dipropylene glycol, Hydrogenated polydecene, Caprylic/capric triglyceride, Cetearyl alcohol, Polyglyceryl-3 methylglucose distearate, Squalane, Niacinamide, Cetyl ethylhexanoate, 1,2-hexanediol, Panthenol, Mangifera indica seed butter, Glyceryl stearate, Diisostearyl malate, Microcrystalline wax, Synthetic beeswax, Vinyl dimethicone, Hydroxyacetophenone, Ammonium acryloyldimethyltaurate/vp copolymer, Sodium polyacryloyldimethyl taurate, Adenosine, Disodium edta, Caprylyl/capryl glucoside, Sodium hyaluronate, Salvia sclarea extract, Madecassoside, Lavandula angustifolia flower extract, Hyacinthus orientalis extract, Chamomilla recutita flower/leaf extract, Centaurea cyanus flower extract, Butylene glycol, Borago officinalis extract, Centella asiatica extract, Ethylhexylglycerin
- Glycerol and the skin: holistic approach to its origin and functions
- Safety Assessment of Polyene Group as Used in Cosmetics
- Niacinamide - mechanisms of action and its topical use in dermatology
- Gehring, W. (2004). Nicotinic acid/niacinamide and the skin. Journal of Cosmetic Dermatology, 3(2), 88–93. doi:10.1111/j.1473-2130.2004.00115.x
- The influence of alkane chain length on the skin irritation potential of 1,2-alkanediols
- Skin moisturizing effects of panthenol-based formulations
- Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
- Extraction and Characteristics of Seed Kernel Oil from Mango
- Promising features of mango (Mangifera indica L.) kernel oil: a review
- Evaluation of the fatty acid composition of the seeds of Mangifera indica L. and their application
- Evaluation of anti-wrinkle efficacy of adenosine-containing products using the FOITS technique
- Hyaluronic acid: A key molecule in skin aging
- Hyaluronan (Hyaluronic Acid): a natural moisturizer for skin care
- Centella asiatica in Dermatology: An Overview
- Protective effect of madecassoside on H2O2-induced oxidative stress and autophagy activation in human melanocytes
- Madecassoside, a triterpenoid saponin isolated from Centella asiatica herbs, protects endothelial cells against oxidative stress
- Madecassoside Inhibits Melanin Synthesis by Blocking Ultraviolet-Induced Inflammation
- Contact dermatitis due to Madecassol
- The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial
- Stability Study of the Active Constituents in the Centella asiatica Extract Formulations
- Evaluation of Skin Irritation and Acute and Subacute Oral Toxicity of Lavandula angustifolia Essential Oils in Rabbit and Mice
- Assessment report on Lavandula angustifolia Mill., aetheroleum and Lavandula angustifolia Mill., flos
- Anti-Inflammatory Effect of Titrated Extract of Centella asiatica in Phthalic Anhydride-Induced Allergic Dermatitis Animal Model
- Centella asiatica in cosmetology
- Triterpene Composition and Bioactivities of Centella asiatica
- Asiaticoside induction for cell-cycle progression, proliferation and collagen synthesis in human dermal fibroblasts
- Assessment report on Centella asiatica (L.) Urban, herba
- Contact dermatitis due to Madecassol