Sesderma Factor G Renew Anti-Ageing Regenerating Cream

Sesderma Factor G Renew Anti-Ageing Regenerating Cream

Efficacy87/100IrritancyMedium

Works for

Moisturizing
Caprooyl tetrapeptide-3, Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1 + 14 more
Works well
What the product description says
“Leaving dry skin thoroughly moisturised with a brighter, more invigorated finish, the Sesderma Factor G Renew Anti-Ageing Regenerating Cream helps to create a more youthful illusion across your face.”
Source: Lookfantastic

This product can help improve hydration of the skin with the two types of ingredients.

The first type is called “humectants”:
these ingredients help attract water. When humectants are on the surface of the skin, they “pull in” the moisture from the outside environment, or from within deeper layers of the skin. The following ingredients in this product do the job: dextran, glycerin.

This product also contains ingredients called “occlusives”. They help reduce the speed with which our skin loses moisture to the outside environment. These ingredients also help soften the upper layer of the skin, so it feels less tight and nicer to the touch. The following ingredients in this product do the job: butyrospermum parkii butter extract, caprylic/capric triglyceride.

The following ingredients in this product are especially good for supporting the skin barrier and helping with the hydration level: caprooyl tetrapeptide-3, nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, palmitoyl tripeptide-5

Caprooyl tetrapeptide-3Hero· EmollientEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%
Palmitoyl tripeptide-5HeroEffect: HighA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Caprylic/capric triglycerideKey active· Emollient, OcclusiveEffect: HighA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin~5.4–6.6%
Prunus amygdalus dulcis oilKey active· EmollientEffect: MediumAn emollient that softens the skin~4.2–5.2%
Butyrospermum parkii butter extractKey active· Emollient, OcclusiveEffect: HighA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals~2.4–3%
DimethiconeKey active· Emollient, OcclusiveEffect: HighA silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish~2–2.4%
Cetyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together~1.4–1.7%
Cetearyl alcoholKey active· EmollientEffect: MediumA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture~0.7–1.05%
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76Key activeEffect: HighA fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization~0.45–0.7%
Centella asiatica extractKey activeEffect: HighA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.55%
GlycerinKey active· HumectantEffect: HighOne of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant~0.25–0.45%
DextranKey active· HumectantEffect: HighHelps attract water to the most upper layer of the skin. Derived from sugar~0.2–0.4%
Glyceryl stearate· EmollientEffect: LowAn emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together~1.6–2%
Lecithin· EmollientEffect: LowUsed mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin~1.1–1.4%
Anti-aging
Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, Caprooyl tetrapeptide-3 + 5 more
May help
What the product description says
“This can result in collagen and elastin production being tripled, leaving your complexion with a suppler feel while also helping to improve the appearance of wrinkles.”
Source: Lookfantastic

This product contains caprooyl tetrapeptide-3, centella asiatica extract, nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, palmitoyl tripeptide-5. These ingredients might be able to help reduce and prevent fine lines and wrinkles, improve skin elasticity and firmness, but there is not enough evidence that it actually works.

Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.6%
Caprooyl tetrapeptide-3Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.35–0.65%
Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.55%
Palmitoyl tripeptide-5Key activeEffect: MediumA type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles~0.2–0.4%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~4.2–5.2%
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76Effect: LowA fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization~0.45–0.7%
Anti-oxidation
Side benefit · Centella asiatica extract, Quercetin + 4 more
May help

This product contains antioxidants (centella asiatica extract, quercetin) that might be able to help neutralize free radicals in skin to lessen the damage it gets from the UV light (sun). There is not enough evidence to confirm their effectiveness in skin though.

Centella asiatica extractKey activeEffect: MediumA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.~0.3–0.55%
QuercetinKey activeEffect: MediumMight be able to help neutralize free radicals in skin~0.15–0.3%
Prunus amygdalus dulcis oilEffect: LowAn emollient that softens the skin~4.2–5.2%
Tocopheryl acetateEffect: LowA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.~0.8–1.2%
Resveratrol dimethyl etherEffect: LowA more stable derivative of anti-oxidant resveratrol. There is not enough research to confirm its efficacy in skin~0.15–0.3%
ErgothioneineUnder-dosedCan help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking~0.2–0.35%

Can it cause trouble?

Irritancy
2 strong irritants: Alcohol, Parfum
Medium risk
We flagged 11 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
AlcoholCan be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial propertiesHigh~0.35–0.65%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~0.15–0.3%est.
Caprylic/capric triglycerideA good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerinMedium~5.4–6.6%est.
Tocopheryl acetateA more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.Medium~0.8–1.2%est.
Centella asiatica extractA plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.Medium~0.3–0.55%est.
Ceteth-20Helps water and oil mix togetherMedium~0.35–0.65%est.
Disodium edtaStabilizes the product formulationMedium~0.2–0.35%est.
EthylhexylglycerinA preservativeMedium~0.2–0.35%est.
Peg-75 stearateHelps water and oil mix togetherMedium~0.2–0.35%est.
Steareth-20Helps oil and water mix togetherMedium~0.25–0.45%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.15–0.25%est.
Comedogenic
2 ingredients rated 2 or more on the 0–5 pore-clogging scale
2 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Butyrospermum parkii butter extractA great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals3/5~2.4–3%est.
Cetearyl alcoholA non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture2/5~0.7–1.05%est.

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Ingredients

Filter by role to see what each ingredient is doing.

Water~45–55%
Formula
Irritation risk
Low

Plain old water

More about Water
Caprylic/capric triglyceride~5.4–6.6%
Key activeIrritant · medium
Irritation risk
Medium
Works for
Moisturizing

A good mix of fatty acids that forms a protective layer on the skin. Improves the shelf life of products. Derived from coconut and glycerin

More about Caprylic/capric triglyceride
Prunus amygdalus dulcis oil~4.2–5.2%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-oxidationAnti-aging

An emollient that softens the skin

More about Prunus amygdalus dulcis oil
Propanediol~3.1–3.8%
Formula
Irritation risk
Low

Acts as a solvent for other ingredients. Speeds up the absorption of other ingredients into the skin

More about Propanediol
Butyrospermum parkii butter extract~2.4–3%
Key activeComedogenic 3/5
Irritation risk
Low
Comedogenicity
3/5
Works for
Moisturizing

A great moisturising ingredient that softens the skin and reduces water loss from its upper layer. It also can be helpful in protecting skin from free radicals

More about Butyrospermum parkii butter extract
Dimethicone~2–2.4%
Key active
Irritation risk
Low
Works for
MoisturizingMattifying

A silicone that helps to reduce water loss from the surface of the skin. Can temporarily "fill in" lines and wrinkles, absorb oil, and create a nice product finish

More about Dimethicone
Glyceryl stearate~1.6–2%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

An emollient that softens the skin and forms a protective layer on its surface. Helps water and oil mix together

More about Glyceryl stearate
Cetyl alcohol~1.4–1.7%
Key active
Irritation risk
Low
Works for
CleansingMoisturizing

A non-drying alcohol that works to soften the skin and stabilize product formulations helping oil and water mix together

More about Cetyl alcohol
Lecithin~1.1–1.4%
Formula
Irritation risk
Low
Works for
CleansingMoisturizing

Used mostly for creating emulsions - helping oil and water mix together. Helps soften the upper layer of the skin

More about Lecithin
Tocopheryl acetate~0.8–1.2%
Irritant · medium
Irritation risk
Medium
Works for
Anti-oxidation

A more stable but less bio-available form of vitamin E compared to Tocopherol. Might help moisturize and protect the skin from free radicals, but mostly used in low concentrations to stabilize other ingredients.

More about Tocopheryl acetate
Cetearyl alcohol~0.7–1.05%
Key activeComedogenic 2/5
Irritation risk
Low
Comedogenicity
2/5
Works for
CleansingMoisturizing

A non-drying alcohol. Works as an emollient. Helps water and oil mix together and creates a nice product texture

More about Cetearyl alcohol
Malus domestica fruit cell culture extract~0.5–0.75%
Formula
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76~0.45–0.7%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging

A fusion peptide that combines peptides produced by human and plant cells. It might have anti-aging effect in skin and can help the skin moisturization

More about Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76
Nicotiana benthamiana hexapeptide-40 sh-polypeptide-2~0.4–0.6%
Formula
Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1~0.35–0.6%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1
Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40~0.35–0.65%
Key active
Irritation risk
Low
Works for
MoisturizingAnti-aging
More about Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40
Alcohol~0.35–0.65%
Irritant · high
Irritation risk
High
Works for
Antibacterial

Can be drying and contribute to skin irritation. Used in formulars to dissolve other ingredients, create a thinner product consistency or for its antibacterial properties

More about Alcohol
Caprooyl tetrapeptide-3~0.35–0.65%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Caprooyl tetrapeptide-3
Carbomer~0.3–0.55%
Formula
Irritation risk
Low
Works for
Cleansing

Helps create a thicker or gel-like product texture. It is not a surfactant but can be used in gentle cleansing formulations

More about Carbomer
Centella asiatica extract~0.3–0.55%
Key activeIrritant · medium
Irritation risk
Medium
Works for
MoisturizingAnti-inflammatoryReduces rednessReduces irritationAnti-oxidationAnti-agingAnti-blemish

A plant extract that has been shown to be able to reduce inflammation in skin, support restoration of skin barrier function, as well as support collagen production. Contains active compounds called centelloids: asiaticoside, madecasosside, asiatic acid and madecassic acid. Might be helpful in preventing stretch marks. It can be itself be irritating though.

More about Centella asiatica extract
Ceteth-20~0.35–0.65%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Ceteth-20
Dextran~0.2–0.4%
Key active
Irritation risk
Low
Works for
Moisturizing

Helps attract water to the most upper layer of the skin. Derived from sugar

More about Dextran
Dipotassium phosphate~0.2–0.35%
Formula
Irritation risk
Low

Used to adjust the pH of the product

More about Dipotassium phosphate
Disodium edta~0.2–0.35%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Ergothioneine~0.2–0.35%
Under-dosed
Irritation risk
Low
Works for
Anti-oxidation

Can help neutralize free radicals in skin. Preliminary studies show that it can be more effective than coenzyme Q10 but studies on effective concentration for topical applications are lacking

More about Ergothioneine
Ethylhexylglycerin~0.2–0.35%
Irritant · medium
Irritation risk
Medium

A preservative

More about Ethylhexylglycerin
Glycerin~0.25–0.45%
Key active
Irritation risk
Low
Works for
Moisturizing

One of the best moisturizing ingredients. Naturally present in skin. It attracts water to the upper layer of the skin working as a humectant

More about Glycerin
Hydrochloric acid~0.2–0.35%
Formula
Nicotiana benthamiana sh-oligopeptide-2
Not recognized
Nicotiana benthamiana sh-polipedtide-45~0.2–0.35%
Formula
Nicotiana benthamiana sh-polypedtide-7~0.2–0.35%
Formula
Palmitoyl tripeptide-5~0.2–0.4%
Hero · Moisturizing
Irritation risk
Low
Works for
MoisturizingAnti-aging

A type of peptide. Peptides are excellent moisturizers and might be able support collagen production reducing fine lines and wrinkles

More about Palmitoyl tripeptide-5
Parfum~0.15–0.3%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Peg-75 stearate~0.2–0.35%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps water and oil mix together

More about Peg-75 stearate
Phenoxyethanol~0.2–0.35%
Formula
Irritation risk
Low

A preservative. It helps prevent bacterial growth in cosmetic products

More about Phenoxyethanol
Polysorbate 20~0.2–0.35%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Potassium phosphate~0.2–0.35%
Formula
Irritation risk
Low

Helps regulate the pH of the formulation

More about Potassium phosphate
Quercetin~0.15–0.3%
Key active
Irritation risk
Low
Works for
Anti-oxidation

Might be able to help neutralize free radicals in skin

More about Quercetin
Resveratrol dimethyl ether~0.15–0.3%
Formula
Irritation risk
Low
Works for
Evens skin toneAnti-oxidation

A more stable derivative of anti-oxidant resveratrol. There is not enough research to confirm its efficacy in skin

More about Resveratrol dimethyl ether
Sodium chloride~0.15–0.3%
Formula
Irritation risk
Low

Used to stabilize mixtures of oil and water, and create thicker, gel-like product textures

More about Sodium chloride
Sodium cholate~0.15–0.25%
Formula
Irritation risk
Low
More about Sodium cholate
Steareth-20~0.25–0.45%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Helps oil and water mix together

More about Steareth-20
Triethanolamine~0.15–0.25%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Tromethamine~0.1–0.15%
Formula
Irritation risk
Low

Helps adjust pH in products

More about Tromethamine
Xanthan gum~0.1–0.15%
Formula
Irritation risk
Low
Works for
Cleansing

Used to create a thicker product consistency

More about Xanthan gum
Ingredient list view

Water, Caprylic/capric triglyceride, Prunus amygdalus dulcis oil, Propanediol, Butyrospermum parkii butter extract, Dimethicone, Glyceryl stearate, Cetyl alcohol, Lecithin, Tocopheryl acetate, Cetearyl alcohol, Malus domestica fruit cell culture extract, Nicotiana benthamiana hexapeptide-40 sh-polypeptide-76, Nicotiana benthamiana hexapeptide-40 sh-polypeptide-2, Nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1, Nicotiana benthamiana sh-polypeptide-15 hexapeptide-40, Alcohol, Caprooyl tetrapeptide-3, Carbomer, Centella asiatica extract, Ceteth-20, Dextran, Dipotassium phosphate, Disodium edta, Ergothioneine, Ethylhexylglycerin, Glycerin, Hydrochloric acid, Unknown, Nicotiana benthamiana sh-polipedtide-45, Nicotiana benthamiana sh-polypedtide-7, Palmitoyl tripeptide-5, Parfum, Peg-75 stearate, Phenoxyethanol, Polysorbate 20, Potassium phosphate, Quercetin, Resveratrol dimethyl ether, Sodium chloride, Sodium cholate, Steareth-20, Triethanolamine, Tromethamine, Xanthan gum

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
SesdermaFactor G Renew Anti-Ageing Regenerating CreamYOUR PRODUCTStriVectinMulti-Action Restorative CreamDRMTLGYPeptide Night CreamDermstore CollectionDay Cream
Match—43%40%40%
Price—$60.23$46.00$33.00
Shared key ingredients—4 of 125 of 125 of 12
Key difference—Acetyl Tetrapeptide-2Ceramide ApCeramide Ap
Irritancy Medium Low Medium Medium
Drying alcohol Contains drying alcohol ———
View product Shop Shop Shop

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Product summary

"Sesderma - Factor G Renew Anti-Ageing Regenerating Cream" is effective for: Moisturizing

This product could be helpful for: Anti-aging and Anti-oxidation, but its actives are not the most effective or are not well-studied.

Ingredient callouts

  • Peptides (palmitoyl tripeptide-5 0.20% - 0.40%, caprooyl tetrapeptide-3 0.35% - 0.65% and nicotiana benthamiana hexapeptide-40 sh-oligopeptide-1 0.35% - 0.60%). Peptides are a very big group of ingredients. They all consist of a different combination of aminoacids. Our skin produces Peptides naturally. Some of them work as natural antibiotics, promote wound-healing and production of collagen. The scientists are still studying how effective the topical application of Peptides is, but it is very likely that theynare helpful. Peptides might be able to support skin barrier restoration and even have an anti-aging benefit. At the very least, they certainly help attract water to the skin and support the hydration in this way.
  • Humectants (glycerin 0.25% - 0.45% and dextran 0.20% - 0.40%). These ingredients help attract water to the upper layer of the skin and improve the skin hydration.

Price

The product retails for 23.00£ in the United Kingdom.

For a detailed price comparison: click here.

Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 15 studies and safety reviews.

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Sesderma Factor G Renew Anti-Ageing Regenerating Cream
SesdermaFactor G Renew Anti-Ageing Regenerating Cream

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