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Replenix Acne Solutions Gly Sal 10-2 Cleanser
Replenix

Replenix Acne Solutions Gly Sal 10-2 Cleanser

Efficacy100/100IrritancyMedium
See all ingredients

Works for

Cleansing
Cocamidopropyl betaine, Polysorbate 20 + 3 more
Cleanses gently
What the product description says
“Acne Solutions Gly Sal 10-2 Cleanser”
From product name

This product works by removing dirt and oil from the surface of the skin. It uses a combination of mild cleansing agents (cocamidopropyl betaine, polysorbate 20, sodium c12-15 pareth-15 sulfonate, sodium c14-16 olefin sulfonate, triethanolamine) and should be able to cleanse the skin gently. Still keep in mind that any cleansing can disrupt the skin barrier, and most people do not need to cleanse their skin more than once per day.

Even though this formulation is mild, the following cleansing agents could trigger an irritation or allergy for some people: cocamidopropyl betaine, sodium c14-16 olefin sulfonate

Cocamidopropyl betaineEffect: HighHelps water and oil mix together. Used as a cleansing ingredient. Could be an allergen~7.8–11.7%
Polysorbate 20Effect: HighHelps oil and water mix together~1.6–2.4%
Sodium c12-15 pareth-15 sulfonateEffect: High~0.5–1.15%
Sodium c14-16 olefin sulfonateEffect: HighHelps oil and water mix together and used as a cleansing agent. Can be irritating and is better avoided for sensitive skin~0.4–1%
TriethanolamineEffect: HighUsed to adjust pH of the product and can help improve the product's smell~0.15–0.5%
Anti-blemish
Salicylic acid, Glycolic acid + 2 more
Works well
What the product description says
“Acne Solutions Gly Sal 10-2 Cleanser”
From product name

This product can help reduce breakouts and clogged pores because it contains the following ingredient: salicylic acid. This ingredient is used for treating acne and can have a noticeable effect.

The following ingredient (ingredients) in this product might be helpful, but there is no evidence to confirm that it actually works: glycolic acid, zinc pca

Salicylic acidHeroEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)2%
Glycolic acidKey activeEffect: MediumAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid10%
Zinc pcaKey activeEffect: MediumA compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing~0.05–0.25%
Camellia sinensis leaf extractEffect: LowCan contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation~23–34%
Exfoliation
Glycolic acid, Salicylic acid
Works well
What the product description says
“Experience a skin-refining cleanse with Topix Gly Sal 10-2 Cleanser , a professional strength cleanser that works to lift away dirt and impurities whilst performing gentle exfoliation.”
Source: Lookfantastic US

This product can help exfoliate the skin. In other words, it helps break down the bonds between dead cells on the surface of the skin and speed up the skin turnover. Skin often appears softer and brighter after exfoliation, but overdoing it can result in disrupted skin barrier. The following ingredient is doing the exfoliating job in this product: glycolic acid, salicylic acid.

Glycolic acidKey activeEffect: HighAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid10%
Salicylic acidKey activeEffect: HighUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)2%

Can it cause trouble?

Irritancy
2 strong irritants: Parfum, Glycolic acid
Medium risk
We flagged 9 ingredients with irritancy potential. Severity depends on your sensitivity threshold; the table lists the worst offenders first.
IngredientFunctionIrritationEst. amount
Salicylic acidUsed for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)High2%
Cocamidopropyl betaineHelps water and oil mix together. Used as a cleansing ingredient. Could be an allergenHigh~7.8–11.7%est.
ParfumAn aromatic blend of unspecified and possibly irritating ingredientsHigh~3–4.6%est.
Glycolic acidAn alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acidHigh10%
Ci 16035A red dyeHigh~0.85–1.25%est.
Sodium c14-16 olefin sulfonateHelps oil and water mix together and used as a cleansing agent. Can be irritating and is better avoided for sensitive skinHigh~0.4–1%est.
Ci 19140A yellow dyeHigh~0.05–0.2%est.
Disodium edtaStabilizes the product formulationMedium~0.5–1%est.
TriethanolamineUsed to adjust pH of the product and can help improve the product's smellMedium~0.15–0.5%est.
Comedogenic
1 ingredient rated 2 or more on the 0–5 pore-clogging scale
1 flagged
These ingredients have a comedogenic rating of 2 or more on a 0–5 scale; the table shows each one's rating. In leave-on products they can clog pores in acne-prone skin.
IngredientFunctionRatingEst. amount
Ci 16035A red dye3/5~0.85–1.25%est.
Alternatives
The closest match we found
Foaming AHA/BHA Acne Treatment Cleanser
Dr. Bailey Skin Care Foaming AHA/BHA Acne Treatment Cleanser
Closest match95% match
View all alternatives

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Ingredients

Filter by role to see what each ingredient is doing.

Salicylic acid2%
Hero · Anti-blemishIrritant · high
Irritation risk
High
Works for
Anti-blemishExfoliationAnti-inflammatoryAntibacterialEvens skin tone

Used for skin exfoliation. It has an anti-inflammatory and anti-bacterial effect, helps to unclog pores, prevent blemishes and speed up healing of the existing ones. Sometimes referred to as a BHA (beta-hydroxy acid)

More about Salicylic acid
Camellia sinensis leaf extract~23–34%
Formula
Irritation risk
Low
Works for
Anti-oxidationAntibacterialAnti-agingAnti-blemishEvens skin toneMoisturizing

Can contain potent anti-oxidant compounds (abbreviated ECG, GCG, EGC, and EGCG) that might help protect the skin from free radicals. Can help calm down inflammation and has some anti-bacterial properties. Unfortunately, these antioxidants are unstable and lose their effectiveness very quickly in products. The concentration of the antioxidant compounds in the extract also tends to be low to be effective in topical formulation

More about Camellia sinensis leaf extract
Cocamidopropyl betaine~7.8–11.7%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps water and oil mix together. Used as a cleansing ingredient. Could be an allergen

More about Cocamidopropyl betaine
Disodium edta~0.5–1%
Irritant · medium
Irritation risk
Medium

Stabilizes the product formulation

More about Disodium edta
Parfum~3–4.6%
Irritant · high
Irritation risk
High

An aromatic blend of unspecified and possibly irritating ingredients

More about Parfum
Glycolic acid10%
Key activeIrritant · high
Irritation risk
High
Works for
Evens skin toneAnti-agingExfoliationAnti-blemish

An alpha-hydroxy acid (AHA) that helps to remove the dead skin cells on the surface of the skin reveling a more even, smoother complexation. It is also able to stimulate collagen production with long-term use. Could help to reduce pore congestion. It can be irritating to the skin. Apply sunscreen daily if using products with glycolic acid

More about Glycolic acid
Linoleamidopropyl pg-dimonium chloride phosphate~2.2–3.3%
Formula
Irritation risk
Low
More about Linoleamidopropyl pg-dimonium chloride phosphate
Polysorbate 20~1.6–2.4%
Formula
Irritation risk
Low
Works for
Cleansing

Helps oil and water mix together

More about Polysorbate 20
Water~1.1–1.6%
Formula
Irritation risk
Low

Plain old water

More about Water
Ci 16035~0.85–1.25%
Comedogenic 3/5Irritant · high
Irritation risk
High
Comedogenicity
3/5

A red dye

More about Ci 16035
Sodium c12-15 pareth-15 sulfonate~0.5–1.15%
Formula
Irritation risk
Low
Works for
Cleansing
More about Sodium c12-15 pareth-15 sulfonate
Sodium c14-16 olefin sulfonate~0.4–1%
Irritant · high
Irritation risk
High
Works for
Cleansing

Helps oil and water mix together and used as a cleansing agent. Can be irritating and is better avoided for sensitive skin

More about Sodium c14-16 olefin sulfonate
Triethanolamine~0.15–0.5%
Irritant · medium
Irritation risk
Medium
Works for
Cleansing

Used to adjust pH of the product and can help improve the product's smell

More about Triethanolamine
Ci 19140~0.05–0.2%
Irritant · high
Irritation risk
High

A yellow dye

More about Ci 19140
Zinc pca~0.05–0.25%
Key active
Irritation risk
Low
Works for
Anti-inflammatoryMoisturizingAnti-blemishAnti-oxidationAnti-aging

A compound that combines zinc with a hydrating ingredient PCA. Might to be helpful against acne and clogged pores. Can help calm down inflammation in skin. Could be helpful in reducing the formation of free radicals in skin. Might help to reduce fine lines in wrinkles, but solid evidence is missing

More about Zinc pca
Ingredient list view

Salicylic acid, Camellia sinensis leaf extract, Cocamidopropyl betaine, Disodium edta, Parfum, Glycolic acid, Linoleamidopropyl pg-dimonium chloride phosphate, Polysorbate 20, Water, Ci 16035, Sodium c12-15 pareth-15 sulfonate, Sodium c14-16 olefin sulfonate, Triethanolamine, Ci 19140, Zinc pca

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Worth comparing, line by line.

Match % combines shared ingredients, the first five ingredients, shared actives and hero ingredients, irritancy (lower counts in the alternative's favour), texture and body area. Only products in the same routine step are compared.

Side-by-side comparison of this product against its closest alternatives
ReplenixAcne Solutions Gly Sal 10-2 CleanserYOUR PRODUCTDr. Bailey Skin CareFoaming AHA/BHA Acne Treatment CleanserMuradMini AHA/BHA Exfoliating CleanserNeutrogenaDeep Clean Purifying Cooling Gel Scrub
Match—95%81%79%
Price——$19.00$8.49
Shared key ingredients—8 of 94 of 94 of 9
Key difference——Lactic AcidAcrylates Crosspolymer-4
Irritancy Medium Medium Low Medium
Drying alcohol————
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Sources cited in this review

Every concentration estimate and effectiveness label is anchored to one of these 11 studies and safety reviews.

  1. 1
    Salicylic acid as a peeling agent: a comprehensive reviewncbi.nlm.nih.gov
  2. 2
    Beta Hydroxy Acidsfda.gov
  3. 3
    A review of toxicity from topical salicylic acid preparationssciencedirect.com
  4. 4
    Glycolic Acid Peels Versus Salicylic–Mandelic Acid Peels in Active Acne Vulgaris and Post‐Acne Scarring and Hyperpigmentation: A Comparative Studyonlinelibrary.wiley.com
  5. 5
    Photoprotective and antiinflammatory effects of topical glycolic acidncbi.nlm.nih.gov
  6. 6
    Glycolic acid peel therapy – a current reviewncbi.nlm.nih.gov
Replenix Acne Solutions Gly Sal 10-2 Cleanser
ReplenixAcne Solutions Gly Sal 10-2 Cleanser
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As an Amazon Associate, WIMJ earns from qualifying purchases.